Effect of cement type on vertical marginal discrepancy and residual excess cement in screwmentable and cementable implant-supported monolithic zirconia crowns
AbstractThe purpose of this study was to investigate the vertical marginal discrepancy (VMD) and residual excess cement (REC) of cementable and screwmentable monolithic zirconia crowns cemented with different types of cement. Abutments were attached to 40 implant analogues. Crowns were created using computer-aided design/computer-aided manufacturing technology from monolithic zirconia blocks, either with or without a screw access hole (SAC). Crowns created both ways were split into two groups and cemented with resin and zinc polycarboxylate cement under a 5-kg weight. VMD and REC values were evaluated using an X20 zoom ste...
Source: Odontology - April 18, 2024 Category: Dentistry Source Type: research
Peri-implantitis with a potential axis to brain inflammation: an inferential review
This study found similarities between PI and PD development, maintenance, and in the bacterial agents located around the teeth (periodontitis) or dental implants (peri-implantitis). Through the cardiovascular system, these pathologies may also affect blood-brain barrier permeability. Furthermore, scientific evidence has suggested that microorganisms from PI (as in PD) can be recognized by trigeminal fiber endings and start inflammatory responses into the trigeminal ganglion. In addition, bacteria can traverse from the mouth to the brain through the lymphatic system. Consequently, the immune system increases inflammatory me...
Source: Odontology - April 17, 2024 Category: Dentistry Source Type: research
The role of MicroRNAs in the diagnosis and treatment of oral premalignant disorders
AbstractOral premalignant disorders (OPMDs) are a group of potentially malignant conditions that pose a significant health burden globally. MicroRNAs (miRNAs), small non-coding RNA molecules, have emerged as crucial regulators of gene expression and have been implicated in various biological processes, including carcinogenesis. This review synthesizes existing knowledge to provide a comprehensive understanding of the molecular mechanisms underlying OPMDs and to highlight the potential of miRNAs as promising biomarkers and therapeutic targets. Additionally, this review seeks to explore the potential of miRNA-based diagnosti...
Source: Odontology - April 15, 2024 Category: Dentistry Source Type: research
A cycle generative adversarial network for generating synthetic contrast-enhanced computed tomographic images from non-contrast images in the internal jugular lymph node-bearing area
In conclusion, synthetic CECT images created by cycleGAN appeared to have the potential to provide effective information in patients who could not receive contrast enhancement. (Source: Odontology)
Source: Odontology - April 12, 2024 Category: Dentistry Source Type: research
Effect of initial periodontal therapy on metallothionein levels in smokers and non-smokers with periodontitis
In conclusion, smoking and periodontitis are associated with higher MT expression which decreases after NSPT. MT as an oxidative stress biomarker and its therapeutic role in perio dontitis should be investigated in future studies.Clinical trial registration: The study was prospectively registered at Clinical Trials Registry —India (ctri.nic.in) as CTRI/2018/08/015427 on August 23, 2018. (Source: Odontology)
Source: Odontology - April 8, 2024 Category: Dentistry Source Type: research
Increased SEC14L2 expression is associated with clinicopathological features and worse prognosis in oral squamous cell carcinoma
AbstractAbnormal expression of SEC14L2 has been implicated in many human cancers. However, the role of SEC14L2 in oral squamous cell carcinoma (OSCC) remains unclear. Therefore, this study aimed to evaluate the expression and prognostic roles of SEC14L2 in OSCC. OSCC tumors and adjacent non-tumors were collected from OSCC patients and used forSEC14L2 mRNA expression by quantitative reverse transcription PCR (RT-qPCR). Additionally, the expression ofSEC14L2 was further analyzed using The Cancer Genome Atlas —Head Neck Squamous Cell Carcinoma (TCGA-HNSCC) dataset to identify its relationship with HNSCC clinical characteris...
Source: Odontology - April 4, 2024 Category: Dentistry Source Type: research
Role of macrophage polarization in periodontitis promoting atherosclerosis
AbstractPeriodontitis is a chronic inflammatory destructive disease occurring in periodontal supporting tissues. Atherosclerosis(AS) is one of the most common cardiovascular diseases. Periodontitis can promote the development and progression of AS. Macrophage polarization is closely related to the development  and progression of the above two diseases, respectively. The purpose of this animal study was to evaluate the effect of periodontitis on aortic lesions in atherosclerotic mice and the role of macrophage polarization in this process. 45 ApoE-/-male mice were randomly divided into three groups: con trol (NC), atheros...
Source: Odontology - April 4, 2024 Category: Dentistry Source Type: research
The efficacy of Er,Cr:YSGG laser and contemporary universal adhesive systems on composite resin repair bond strength: an in vitro study
AbstractThe aim of this study is to investigate the repair bond strength of composite resin following three different surface treatments (bur-grinding, silanization, and Er,Cr:YSGG laser irradiation) using various universal adhesives. A total of 160 resin composite specimens, produced in cylindrical form (6  × 2 mm) with a nanohybrid composite resin within metal molds, were subjected to 5000 cycles of aging in a thermocycler. The aged samples were categorized into four groups based on surface treatments: control, bur, silane, and Er,Cr:YSGG laser. Following surface treatments, the specimens under went repair using th...
Source: Odontology - April 3, 2024 Category: Dentistry Source Type: research
Tooth whitening: current status and prospects
AbstractAs a safe, effective, economical, and convenient technique, tooth whitening is one of the most popular treatments for improving tooth discoloration. This review summarizes the theoretical and recent research developments in the classification and mechanisms of tooth discoloration, as well as the principles, agents, effects, and side effects of tooth whitening techniques. The aim is to provide a basis for the clinical treatment of tooth whitening techniques and to suggest possible new ideas for further research. The accepted mechanism of whitening is the redox reaction of oxides in the whitening reagent, and the whi...
Source: Odontology - April 3, 2024 Category: Dentistry Source Type: research
The current overview of the devices of temporary anchorage placed on the palatal bone: CBCT study
AbstractTemporary anchorage devices (TADs) are frequently applied to different anatomic areas with different protocols to increase skeletal effects and anchorage in orthodontic treatment planning. It has been reported in many literatures that primary stability for orthodontic TADs is significant for long-term survival rate. For this reason, different areas of the palatal region, which has many indications, have been widely used in the studies. In this evaluation where bone quality and thickness are important, density, bone thickness, and fractal dimension (FD) on cone beam computed tomography (CBCT) will provide more predi...
Source: Odontology - April 2, 2024 Category: Dentistry Source Type: research
Bacterial contamination potential of personal protective equipment itself in dental aerosol-producing treatments
AbstractPersonal protective equipment (PPE) has long been a high priority in dental aerosol-producing treatments. Since COVID-19 pandemic, its importance has increased yet again. While importance of PPE in preventing transmission and thus possible infection of pathogens is well known, contamination potential of PPE after treatment itself is less investigated. This review aims to give an overview of the current literature and contamination potential (viral, blood, bacterial) of components of protective equipment itself. The literature search was performed using the Medline database; furthermore, a hand search was conducted....
Source: Odontology - March 11, 2024 Category: Dentistry Source Type: research
Videofluoroscopic analysis of the laryngeal movement of older adults in swallowing
This study analyzed age-related changes in laryngeal movement in older adults. The study population consisted of 10 volunteers in their 80s and six in their 20s. A videofluoroscopic study of 3 and 10 Â mL barium swallows was performed laterally using a digital fluorographic. The recorded images were retrieved to a personal computer and analyzed frame-by-frame using video analysis software. The movement of the larynx during swallowing, barium's pharyngeal transit time (PTT), and laryngeal elevati on delay time (LEDT) were analyzed. Results were compared between the 20s and 80s age groups using statistical analyses. The PTT ...
Source: Odontology - March 11, 2024 Category: Dentistry Source Type: research
Influence of systemic antibiotic therapy on the development and progression of induced apical periodontitis in Wistar rats
AbstractThe aim of this study was to investigate the influence of systemic antibiotic therapy on the development and progression of induced apical periodontitis (AP) in Wistar rats. Fifty-six rats were submitted to pulp exposure of the lower left first molar for the induction of AP. On the same day, intraperitoneal antibiotic therapy was administered once a day, for 15  days, until euthanasia. The groups were formed according to the different treatments (n = 8): C—control; GEN—treated with gentamicin (10 mg/Kg); AC—treated with amoxicillin (100 mg/Kg); MZ—treated with metronidazole (40 mg/Kg); AMP—treated...
Source: Odontology - March 8, 2024 Category: Dentistry Source Type: research
Associations between immune-inflammatory markers, age, and periodontal status: a cross-sectional study
This study suggests a significant increase in host response to periodontal disease as the disease progresses, with the levels of cytokines and TLR expression exhibiting an increasing trend with age. Increased IL-17, IL-18, TLR2, TLR4, and TNF-α levels in elderly individuals in all periodontal health subgroups might suggest the role of these cytokines and TLR pathway in the pathogenesis of periodontal diseases. (Source: Odontology)
Source: Odontology - March 6, 2024 Category: Dentistry Source Type: research
Postoperative pain of minimally invasive root canal treatment:a randomized clinical trial
AbstractThis randomized clinical trial compared postoperative pain between a minimally invasive (MP) and conventional root canal treatment protocol (CP). A total of 170 mature permanent teeth (either with vital or necrotic pulp), were randomly assigned into two groups. In the CP group, ProTaper Gold (Dentsply Sirona, Ballaigues, Switzerland) and a continuous wave of condensation technique were used, whereas, in the MP group, TruNatomy (Dentsply Sirona), ultrasonic-assisted irrigation (UI), calcium hydroxide, and a sealer-based obturation technique were used. Patients recorded preoperative and postoperative pain using a 0 â...
Source: Odontology - March 1, 2024 Category: Dentistry Source Type: research
