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Lymphoproliferative Disorders in Patients Receiving Thiopurines for Inflammatory Bowel Disease: A Prospective Observational Cohort StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients receiving thiopurines for inflammatory bowel disease have an increased risk of developing lymphoproliferative disorders. Background: Reports of an increased risk of lymphoproliferative disorders... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 19, 2009 Category: Cancer & Oncology Source Type: journals

Clinical Experiences With Bisphosphonate-Associated Osteonecrosis of the Jaws: Analysis of 21 CasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The majority of the cases affected the mandible and were associated with IV zoledronate treatment for bone metastasis. Dentoalveolar trauma to the mandible appeared to be a contributing factor. Conservative... Purpose:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 18, 2009 Category: Cancer & Oncology Source Type: journals

Comparative Survival With Diverse Chemotherapy Regimens for Cancer of Unknown Primary Site: Multiple-Treatments Meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No type of chemotherapy has been solidly proven to prolong survival in patients with cancer of unknown primary site. However, some analyses favour platinum- or taxane-based regimens. Objectives: To synthesize... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Fluorouracil, Epirubicin, and Cyclophosphamide With Either Docetaxel or Vinorelbine, With or Without Trastuzumab, as Adjuvant Treatments of Breast Cancer: Final Results of the FinHer TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this open, phase III, prospective, multicenter trial of adjuvant chemotherapy in patients with node–positive or high-risk node-negative breast cancer, docetaxel was more effective than vinorelbine in... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Bortezomib and High Dose Melphalan as Conditioning Regimen Before Autologous Stem Cell Transplantation in Patients With de Novo Multiple MyelomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this phase II study of 54 patients with newly diagnosed multiple myeloma, pre-transplant conditioning with bortezomib plus high-dose melphalan was safe and effective, resulting in a post-transplant... Autologous... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Relapse Risk After Umbilical Cord Blood Transplantation: Enhanced Graft-Versus-Leukemia Effect in Recipients of 2 UnitsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
UCB transplant with 2 partially HLA-matched units enhances graft-vs-leukemia effect and lowers the risk of relapse. Umbilical cord blood (UCB) transplantation is potentially curative for acute leukemia.... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Adjuvant Capecitabine in Combination With Docetaxel and Cyclophosphamide Plus Epirubicin for Breast Cancer: An Open-Label, Randomised Controlled TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recurrence-free survival at 3 years was superior for treatment with a capecitabine regimen over standard agents (93% vs 89%). Adverse effects frequently caused discontinuation of capecitabine, but most... Background:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 17, 2009 Category: Cancer & Oncology Source Type: journals

Clinical Relevance of HER2 Overexpression/Amplification in Patients With Small Tumor Size and Node-Negative Breast CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this retrospective analysis of 150 patients with HER2-positive pT1a/bN0M0 breast cancer and 229 matched controls, HER2-positive status was associated with a significantly higher risk of recurrence than... Related... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 14, 2009 Category: Cancer & Oncology Source Type: journals

High Risk of Recurrence for Patients With Breast Cancer Who Have Human Epidermal Growth Factor Receptor 2–Positive, Node-Negative Tumors 1 cm or SmallerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this retrospective study of 935 patients, T1a/T1b HER2-positive breast cancer was associated with more aggressive biology and higher risk of recurrence. The results were validated in a separate cohort... Related... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 14, 2009 Category: Cancer & Oncology Source Type: journals

A Prospective Cohort Study Shows Unique Epigenetic, Genetic, and Prognostic Features of Synchronous Colorectal CancersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Synchronous CRC tumors were more likely than solitary cancers to have BRAF mutations, high microsatellite instability, and CIMP. Background & Aims: Synchronous colorectal neoplasias (2 or more primary... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 12, 2009 Category: Cancer & Oncology Source Type: journals

Calibration and Discriminatory Accuracy of Prognosis Calculation for Breast Cancer With the Online Adjuvant! Program: A Hospital-Based Retrospective Cohort StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Large-scale Dutch study validated Adjuvant! as accurately predicting 10-year outcomes in patients with breast cancer. Background: Adjuvant! is a web-based program that calculates individualised 10-year... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 12, 2009 Category: Cancer & Oncology Source Type: journals

Neurocognition in Patients With Brain Metastases Treated With Radiosurgery or Radiosurgery Plus Whole-Brain Irradiation: A Randomised Controlled TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients with newly diagnosed brain metastasis who were randomly assigned to SRS plus WBRT (28) were more likely to show a significant drop in HVLT–R total recall at 4 months than were patients randomly... Background:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 12, 2009 Category: Cancer & Oncology Source Type: journals

VMP (Bortezomib, Melphalan, and Prednisone) Is Active and Well Tolerated in Newly Diagnosed Patients With Multiple Myeloma With Moderately Impaired Renal FunctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cohort analysis of the VISTA data showed that VMP was well tolerated and was superior to MP in patients with moderate renal impairment, reversing impairment in 44%. Related Links: Access this article... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 10, 2009 Category: Cancer & Oncology Source Type: journals

Long Term Outcome of EBV Specific T-Cell Infusions to Prevent or Treat EBV-Related Lymphoproliferative Disease in Transplant RecipientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
EBV-specific cytotoxic T lymphocytes safely prevented or treated lymphoproliferative disease in SCT recipients. T-cell immunotherapy that takes advantage of Epstein-Barr virus (EBV)-stimulated immunity... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 10, 2009 Category: Cancer & Oncology Source Type: journals

High-Dose Cytarabine Plus High-Dose Methotrexate Versus High-Dose Methotrexate Alone in Patients With Primary CNS Lymphoma: A Randomised Phase 2 TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The complete remission rate was 46% with high-dose cytarabine plus high-dose methotrexate compared with 18% for high-dose methotrexate alone in patients with in CNS lymphoma. Background: Chemotherapy... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 10, 2009 Category: Cancer & Oncology Source Type: journals

Development and Validation of a Prognostic Nomogram for Recurrence-Free Survival After Complete Surgical Resection of Localised Primary Gastrointestinal Stromal TumourEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nomogram based on tumor size, location, and mitotic index predicts RFS after resection of localized primary GIST. Background: Adjuvant imatinib mesylate prolongs recurrence-free survival (RFS) after resection... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 10, 2009 Category: Cancer & Oncology Source Type: journals

Epidemiological Study on Survival of Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL) Patients With BCR-ABL T315I MutationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients with BCR-ABL–positive (Ph+) leukemia, the T315I mutation is associated with a high degree of resistance to imatinib, dasatinib, and nilotinib. Little published information exits regarding the... The... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 7, 2009 Category: Cancer & Oncology Source Type: journals

Advances in Imaging in the Work-Up of Head and Neck Cancer PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Current roles of CT and MRI in diagnosing HNSCC are discussed, along with the value of FDG-PET-CT in detecting occult LN metastases. Accurate staging at the time of the diagnosis of head and neck squamous... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 7, 2009 Category: Cancer & Oncology Source Type: journals

Surgical Management of Liver Metastases From Uveal Melanoma: 16 Years' Experience at the Institut CurieEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
R0 surgical resection almost doubled survival, to 27 months, in this single-institution experience. Background: Uveal melanoma is characterised by a high prevalence of liver metastases and a poor prognosis. Aim:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 5, 2009 Category: Cancer & Oncology Source Type: journals

Predictive Value of FIGO and AJCC Staging Systems in Patients With Uterine LeiomyosarcomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Neither the FIGO nor the AJCC system adequately classifies ULMS patients into clinically meaningful prognostic groups. Background: Cancer staging systems aim to identify patient cohorts with different... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 5, 2009 Category: Cancer & Oncology Source Type: journals

Cancer During Pregnancy: An Analysis of 215 Patients Emphasizing the Obstetrical and the Neonatal OutcomesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this observational study of pregnancy outcomes in 215 women with invasive cancer, a substantial percentage of babies (54.2%) were born preterm. The majority of the preterm babies (85.2%) required admission... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 31, 2009 Category: Cancer & Oncology Source Type: journals

Randomized Phase III Trial on Gemcitabine Versus Mytomicin in Recurrent Superficial Bladder Cancer: Evaluation of Efficacy and ToleranceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite adjuvant BCG therapy after transurethral resection for superficial bladder cancer, recurrence often occurs. In this randomized, phase III study of 109 patients with recurrent stage T1/T1a bladder... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 31, 2009 Category: Cancer & Oncology Source Type: journals

Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this phase II study of 73 patients with untreated, Ph+, early-phase CML, nilotinib 400 mg twice daily was associated with a 1-year complete cytogenetic response rate of 96% and a major molecular response... Nilotinib... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics and outcome from the large randomised prospective trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No standard of care exists for patients with adult T-lineage acute lymphoblastic leukemia (ALL). In this prospective, randomized trial of 356 patients, Marks et al describe clinical features, cytogenetics... The... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

Evidence of serum immunoglobulin abnormalities up to 9.8 years prior to diagnosis of chronic lymphocytic leukemia: a prospective studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study of 109 patients who were identified during the PLCO Cancer Screening Trial, abnormal free light chain ratio and M-protein level preceded diagnosis of CLL by to 10 years. Hypogammaglobinemia... Immune-related... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In vitro studies conducted in progenitor cells from patients with chronic-phase chronic myeloid leukemia demonstrated that transient Bcr-Abl inhibition using dasatinib or nilotinib induced apoptosis. This... Pioneering... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

Clinical Outcome of Dose-Escalated Image-Guided Radiotherapy for Spinal MetastasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Excellent local control of spinal metastases and paraspinal tumors was achieved with dose-escalated irradiation. Purpose: To evaluate the outcomes after dose-escalated radiotherapy (RT) for spinal metastases... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

Preoperative Intensity-Modulated Radiotherapy Combined with Temozolomide for Locally Advanced Soft-Tissue SarcomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Intensity-modulated radiotherapy plus temozolomide was safe and effective before surgery for soft-tissue sarcoma. Purpose: To evaluate the toxicity and efficacy of preoperative intensity-modulated radiotherapy... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 27, 2009 Category: Cancer & Oncology Source Type: journals

Alpha-Fetoprotein Response After Locoregional Therapy for Hepatocellular Carcinoma: Oncologic Marker of Radiologic Response, Progression, and SurvivalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
AFP response was a prognostic indicator for radiologic tumor response and OS in patients receiving locoregional therapy for HCC. Access this article » ... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 24, 2009 Category: Cancer & Oncology Source Type: journals

Local Excision Alone Without Irradiation for Ductal Carcinoma in Situ of the Breast: A Trial of the Eastern Cooperative Oncology GroupEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this prospective analysis, women with low- and intermediate-grade ductal carcinoma in situ of the breast (n = 565) were at low risk (6%) for recurrence at 5 years after excision without radiation therapy.... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 24, 2009 Category: Cancer & Oncology Source Type: journals

Pegylated Interferon Alfa-2a Yields High Rates of Hematologic and Molecular Response in Patients With Advanced Essential Thrombocythemia and Polycythemia VeraEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this prospective, open-label, single-center, phase II trial of PEGIFN-2a in 70 patients with advanced ET or PV, PEGIFN-2a was effective and well tolerated at 90 µg weekly. PEG-IFN-2a was associated... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 24, 2009 Category: Cancer & Oncology Source Type: journals

Venous Thromboembolism in Lymphoma: How Effectively Are We Treating Patients?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Warfarin treatment in lymphoma patients was linked with a 30% rate of recurrent thrombosis and a 13% rate of major bleeding. Introduction: Patients with solid tumors and venous thromboembolic episodes... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 21, 2009 Category: Cancer & Oncology Source Type: journals

Multinational, Double-Blind, Phase III Study of Prednisone and Either Satraplatin or Placebo in Patients With Castrate-Refractory Prostate Cancer Progressing After Prior ChemotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This randomized phase III study of 950 patients with castrate-refractory prostate cancer compared the efficacy of satraplatin plus prednisone with that of prednisone alone. Satraplatin plus prednisone... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 20, 2009 Category: Cancer & Oncology Source Type: journals

Phase III Trial of Casopitant, a Novel Neurokinin-1 Receptor Antagonist, for the Prevention of Nausea and Vomiting in Patients Receiving Moderately Emetogenic ChemotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of this randomized, controlled, parallel-group, phase III clinical trial of 1933 patients showed that addition of casopitant to ondansetron and dexamethasone was effective in preventing chemotherapy-induced... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 20, 2009 Category: Cancer & Oncology Source Type: journals

AML1/RUNX1 Mutations in 470 Adult Patients With de Novo Acute Myeloid Leukemia: Prognostic Implication and Interaction With Other Gene AlterationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
RUNX1 mutation was an independent prognostic factor for poor overall survival in patients with de novo AML. Somatic mutation of AML1/RUNX1(RUNX1) gene is seen in acute myeloid leukemia (AML) M0 subtype... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 20, 2009 Category: Cancer & Oncology Source Type: journals

Surgery With Curative-Intent in Patients Treated With First-Line Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer. First BEAT and the Randomised Phase-III NO16966 TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two studies, First BEAT and NO16966 Trial, evaluated the safety and survival effect of bevacizumab in patients undergoing surgery for metastatic colorectal cancer. Background: Complete resection of metastases... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 20, 2009 Category: Cancer & Oncology Source Type: journals

Allogeneic Stem Cell Transplantation After Reduced-Intensity Conditioning in Patients With MyelofibrosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The prospective multicenter phase II study evaluated the use of reduced intensity conditioning (RIC) with busulfan plus fludarabine in patients with primary myelofibrosis. RIC was followed by allogeneic... From... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 20, 2009 Category: Cancer & Oncology Source Type: journals

Risk of Bleeding With Vascular Endothelial Growth Factor Receptor Tyrosine-Kinase Inhibitors Sunitinib and Sorafenib: A Systematic Review and Meta-analysis of Clinical TrialsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this meta-analysis of nearly 7000 patients, sunitinib and sorafenib significantly increased the risk of bleeding. Clinicians should be aware of the possibility of increased bleeding, especially in patients... Background:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 17, 2009 Category: Cancer & Oncology Source Type: journals

AML With Mutated NPM1 Carrying a Normal or Aberrant Karyotype Show Overlapping Biologic, Pathologic, Immunophenotypic, and Prognostic FeaturesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results of this study of 631 patients with AML strongly suggest that the NPM1 gene mutation, which is present in 30% of adult AML cases, is at the root of the underlying disease mechanism in AML. Concomitant... Acute... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 17, 2009 Category: Cancer & Oncology Source Type: journals

Sentinel Lymph Node Surgery After Neoadjuvant Chemotherapy Is Accurate and Reduces the Need for Axillary Dissection in Breast Cancer PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study of 3746 women with node-negative T1-T3 breast cancer, sentinel lymph node surgery after neoadjuvant chemotherapy had similar detection rates and false-negative rates when compared with surgery... Objective:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 17, 2009 Category: Cancer & Oncology Source Type: journals

A Population-Based Analysis of the Rate of Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma in the United StatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although cytoreductive nephrectomy improves survival in patients with mRCC, racial and geographic variability in its use is worrisome. Objective: To examine temporal, geographic, socioeconomic, and clinical... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 14, 2009 Category: Cancer & Oncology Source Type: journals

Abnormal Serum Free Light Chain Ratio in Patients With Multiple Myeloma in Complete Remission Has Strong Association With the Presence of Oligoclonal Bands: Implications for Stringent Complete Remission DefinitionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The correlation between abnormal FLC ratio and oligoclonal bands in patients with MM in complete response may have implications for the current definition of stringent CR. The prevalence of an abnormal... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 14, 2009 Category: Cancer & Oncology Source Type: journals

Chronic Myeloid Leukemia: A Prospective Comparison of Interphase Fluorescence in Situ Hybridization and Chromosome Banding Analysis for the Definition of Complete Cytogenetic ResponseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Interphase-FISH is more sensitive than chromosome banding analysis and can be used to monitor complete cytogenetic response. The cut-off value of Interphase-FISH may be established at 1%. In chronic myeloid... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 14, 2009 Category: Cancer & Oncology Source Type: journals

High Id1 Expression Is Associated With Poor Prognosis in 237 Patients With Acute Myeloid LeukemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients with AML, especially those age 60 years, high Id1 expression independently predicted shorter DFS and OS. Id1 expression may thus be a new molecular marker useful in risk classification. Inhibitors... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 14, 2009 Category: Cancer & Oncology Source Type: journals

Can Chemotherapy Be Discontinued in Unresectable Metastatic Colorectal Cancer? The GERCOR OPTIMOX2 StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The results of the OPTIMAX2 study showed that maintenance therapy with simplified LV5FU2 between induction and reintroduction with mFOLFOX7 reduced the risk of oxaliplatin failure by 29% when compared... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 13, 2009 Category: Cancer & Oncology Source Type: journals

Defining Prior Therapy in Myelodysplastic Syndromes and Criteria for Relapsed and Refractory Disease: Implications for Clinical Trial Design and EnrollmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The recent approval of 3 drugs for the treatment of myelodysplastic syndromes (MDSs) has resulted in a revolution in therapeutic options that was absent a decade ago. At the same time, the changing MDS... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 8, 2009 Category: Cancer & Oncology Source Type: journals

Factors Associated With Clinical Benefit From Epidermal Growth Factor Receptor Inhibitors in Recurrent and Metastatic Squamous Cell Carcinoma of the Head and NeckEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Older age, better performance status, and rash were related to clinical benefit from EGFR treatment for head and neck cancer. Single agent epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 8, 2009 Category: Cancer & Oncology Source Type: journals

Association of Age and Survival in Patients With Gastroesophageal Cancer Undergoing Surgery With or Without Preoperative TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this retrospective analysis of 600 patients with esophageal cancer, patients >60 years of age and especially those >70 years had shorter long-term OS and DFS and more postoperative complications than... Background:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 8, 2009 Category: Cancer & Oncology Source Type: journals

Dasatinib Treatment of Chronic Phase Chronic Myeloid Leukemia: Analysis of Responses According to Preexisting BCR-ABL MutationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study of 1043 patients, dasatinib was associated with durable responses in patients with chronic phase CML who had progressive disease after prior imatinib treatment, regardless of BCR-ABL mut... Dasatinib... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - October 6, 2009 Category: Cancer & Oncology Source Type: journals

Cost of a 5-Year Lung Cancer Survivor: Symptomatic Tumour Identification vs Proactive Computed Tomography ScreeningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The cost per 5-year survivor was considerably lower with CT screening than with the symptom-detected approach, especially for patients over age 60, and the number of 5-year survivors was greater. Background:... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - September 29, 2009 Category: Cancer & Oncology Source Type: journals