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ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Tags: This Issue At a Glance Source Type: journals

This Issue At A GlanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Baltimore Pediatric Eye Disease Survey assessed the prevalence of strabismus and amblyopia among African-American and white preschool children aged 6 months through 71 months living in Baltimore city and adjacent Baltimore county. Among 4,132 children identified, 3,990 eligible children (97%) were enrolled and 2,546 (62%) were examined. Friedman et al (p. 2128) found that overall prevalence of strabismus was 2.1% in African Americans and 3.3% in whites, which was not a statistically significant difference. Exotropia and esotropia were found equally often in both racial groups, and were about 3 times more frequent in ch...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Lori Baker Schena, John Kerrison Tags: This Issue At a Glance Source Type: journals

Editorial BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Tags: Frontmatter Source Type: journals

Systems-Based CompetencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dr. Lum and Dr. Schachat emphasized in their recent editorial the need to foster a culture of safety and transparency in order to reduce or preferably eliminate “never events” in ophthalmology (e.g., wrong site surgery or wrong intraocular lens). In a parallel process, the Accreditation Council for Graduate Medical Education (ACGME) has mandated that all residency programs in the U.S. teach and assess 6 general competencies. One of these competencies is systems-based practice (SBP), which the ACGME defines as follows: “Residents must demonstrate an awareness of and responsiveness to the larger context and system of h...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Andrew G. Lee Tags: Letters to the Editor Source Type: journals

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We are grateful to Cannon et al for their valuable comments on our study. For the patient's management it is important to differentiate between solid and fibrous basal cell carcinoma (BCC). We emphasize that we routinely re-excise cases with incompletely excised BCC, as we've recommended in our discussion. Even in solid BCC, when the histological margins are small (under 80 μm), we prefer to re-excise rather than leave a small histological safety margin. However, we believe our study's results could serve as a basis for discussing alternative approaches deserving of consideration when clinicians have to treat patients who...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Claudia Auw-Haedrich, Stefanie Frick, Daniel Boehringer, Hans Mittelviefhaus Tags: Letters to the Editor Source Type: journals

Basal Cell CarcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We read with interest the recent article by Auw-Haedrich et al in which they set out to recommend an appropriate and reliable histological safety margin in the surgical excision of periorbital basal cell carcinoma (BCC). The authors conclude that in certain cases of incomplete excision where re-excision may lead to functional or cosmetic morbidity it may be reasonable to observe. This conclusion is based on their data of 11 patients with incompletely excised tumors of which 27% recurred. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Paul S. Cannon, Shyamala C. Huilgol, Dinesh Selva, Raman Malhotra Tags: Letters to the Editor Source Type: journals

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We thank Dr. Garibaldi and colleagues for their comments regarding our recent publication and would like to comment on several issues raised in their correspondence. First, we do not claim to be the first to publish the “sutureless” technique for orbital fracture repair. In our paper, we clearly cite the work of Ho and colleagues, who described this technique in the repair of 26 isolated orbital floor fractures. Our series expanded the indications to include more complex orbital and midfacial fractures. As to the contention that this technique has been used by others, we have no way to confirm or refute this, except to...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: K.A. Lane, J.R. Bilyk, D. Taub, E.A. Pribitkin Tags: Letters to the Editor Source Type: journals

Repair of Orbital FracturesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We read with interest the article by Lane et al presenting the “sutureless” repair of orbital floor and rim fractures. We agree that this widely used technique has long been a successful alternative to multilayered conjunctival and periosteal closure in the repair of orbital fractures and were surprised to discover that it had not been previously described in detail. To the authors' 38 “pure” orbital floor fractures we would add 191 patients with isolated floor fractures who underwent successful repair using this approach and had been previously reported in papers discussing 2 distinct alloplastic implants. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Daniel C. Garibaldi, Shannath L. Merbs, Michael P. Grant Tags: Letters to the Editor Source Type: journals

Bevacizumab Local ComplicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bevacizumab (Avastin, Genetech, San Francisco, CA) is a recombinant monoclonal antibody (IgG1) that selectively binds and neutralizes the biological activity of vascular endothelial growth factor. Its intravenous administration was approved by the Food and Drug Administration (FDA) in February 2004 as a first-line therapy for metastatic colorectal cancer. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Maximiliano Gordon-Angelozzi, Raul Velez-Montoya, Jans Fromow-Guerra, Gerardo García-Aguirre, Jose Luis Guerrero-Naranjo, Hugo Quiroz-Mercado, Virgilio Morales-Cantón Tags: Letters to the Editor Source Type: journals

Angiographic Changes after BevacizumabEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Intravitreal bevacizumab (IVB) (Avastin, Genentech Inc, South San Francisco, CA) is currently one of the most widely used treatments for myopic choroidal neovascularization (mCNV). IVB can improve and preserve vision in many patients at 1 year. However, the impact of IVB on the choroid/retinal pigment epithelium (RPE) is still uncertain. For example, marginal crack formation around the mCNV has been reported after treatment for mCNV. Indocyanine green angiography (ICGA) using a confocal system is useful for evaluating the RPE or choroidal damage in highly myopic eyes. We investigated the status of the RPE/choroid after IVB...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Yasushi Ikuno, Kaori Soga, Taku Wakabayashi, Fumi Gomi Tags: Letters to the Editor Source Type: journals

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I read attentively Bhatia and Narayanan's comments questioning the gold standard used in our study. They suggest that funduscopic examination (the gold standard for posterior vitreous detachment [PVD] evaluation) should have been performed by 1 or 2 retina specialists in a standardized manner instead of general ophthalmologists. In agreement with their comments, in the introduction and discussion sections, we have recognized that indirect ophthalmoscopy with indentation is the gold standard technique to examine the peripheral retina in PVD cases. Our approach to validate the index test was based on the following assumption...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: José Lorenzo-Carrero Tags: Letters to the Editor Source Type: journals

USG B Scan for Retinal Tears in PVDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We read with interest the article by Lorenzo-Carrero et al entitled, “B-scan ultrasonography to screen for retinal tears in acute symptomatic age-related posterior vitreous detachment.” We offer a few comments. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Kapil Bhatia, Raja Narayanan Tags: Letters to the Editor Source Type: journals

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We would like to thank Dr. Brown for her interest in our paper and allowing us to more fully describe our low-light pupil testing protocol. We measured the low-light pupils with the infrared pupillometer incorporated into the Nidek auto-refractor (Nidek, Gamagori, Japan). All patients followed a specific testing protocol which began when they were brought into a dimly lit testing room and allowed to dark adapt for several minutes. The room light level was specifically matched to the luminance of the night driving simulator (1 cd/m2), which represented the reflection of headlights off of the pavement. The patients were the...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Steve Schallhorn, Dave Tanzer, Sandor Kaupp, Mitch Brown Tags: Letters to the Editor Source Type: journals

Night Driving After LASIKEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
I read with interest the article by Schallhorn et al comparing night driving performance after conventional (c-) and wavefront-guided (w-) laser in situ keratomileusis (LASIK). Testing was performed with a night driving simulator (NDS), and I have personally undergone this fascinating process. I congratulate the authors for using a legitimate assessment of an important life function as opposed to an inadequate proxy such as self-reported difficulty on a satisfaction survey. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Sandra Brown Tags: Letters to the Editor Source Type: journals

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We appreciate the interest and important comments from Dr. Weiss regarding our article on Schnyder corneal dystrophy. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Akira Kobayashi, Kazuhisa Sugiyama, Akira Murakami, Keiko Fujiki Tags: Letters to the Editor Source Type: journals

More on Schnyder Corneal DystrophyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
I write concerning the recent report of Kobayashi et al. The authors solely credit Orr et al with identification of the UBIAD1 gene as the cause of Schnyder corneal dystrophy (SCD), but I would like to point out that our group independently discovered and published the finding that mutations in UBIAD1 gene caused SCD. Although the figure legends for the slit lamp photographs emphasize the central disciform opacity, crystalline deposits, and arcus lipoides; all of their patients also demonstrate the classic midperipheral corneal haze that is noted in patients 40 years of age and older but is often not appreciated. The autho...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Jayne S. Weiss Tags: Letters to the Editor Source Type: journals

Smoking and Corneal BiomechanicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Changes in the biomechanical properties of the human cornea play an important role in the pathogenesis of corneal dystrophies such as pellucid marginal corneal degeneration and keratoconus. The latter primarily affects young people and is a leading cause of severe visual impairment. Keratoconus is characterized by weakened corneal biomechanics that leads to progressive bulging and thinning of the cornea. Spoerl et al have shown recently that the incidence of keratoconus is distinctly reduced in smokers suggesting that smoking improves the biomechanical properties of the cornea. This hypothesis is further supported by studi...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Farhad Hafezi Tags: Letters to the Editor Source Type: journals

Happy 50th BirthdayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In mid-November, 1959 the first human fluorescein angiogram was performed on me, and photographs of my right eye were taken. An original 8×10 inch glossy print of that event with a copy of the paper Harold Novotny and I wrote for the journal Circulation is in the Museum of Vision of the American Academy of Ophthalmology. (Source: Ophthalmology)
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: David Alvis Tags: Letters to the Editor Source Type: journals

Phakic Intraocular Lens Implantation for the Correction of Myopia: A Report by the American Academy of OphthalmologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Phakic IOL implantation is effective in the correction of myopia and myopic astigmatism. In cases of high myopia of −8 diopters or more, pIOLs may provide a better visual outcome than keratorefractive surgeries and better safety than refractive lens exchange. The short-term rates of complications and loss of BSCVA are acceptable. Comprehensive preoperative evaluation and long-term postoperative follow-up examinations are needed to monitor for and prevent serious complications, and to establish long-term safety.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (S...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: David Huang, Steven C. Schallhorn, Alan Sugar, Ayad A. Farjo, Parag A. Majmudar, William B. Trattler, David J. Tanzer Tags: Ophthalmic Technology Assessment Source Type: journals

Demographics, Etiology, and Behavior of Conjunctival Squamous Cell Carcinoma in the 21st CenturyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The cancer of the squamous epithelium was labeled as “epithelioma” by Rudolph Virchow in the 1850s, but over the course of a century, its name gradually changed to squamous cell carcinoma (SCC). Although ophthalmologists deal with many primary, secondary, and metastatic forms of SCC in the eye and ocular adnexae, they tend to consider SCC arising in the conjunctiva as their “own” disease and typically assume responsibility for diagnosis and management of this disorder. Between the turn of the 20th century and the mid-1960s, this lesion underwent an identity crisis in which it was given many different names, includi...
Source: Ophthalmology - November 1, 2009 Category: Opthalmology Authors: Zeynel A. Karcioglu, Michael D. Wagoner Tags: Editorial Source Type: journals

Five-year Results of a Randomized Trial with Open-label Extension of Triamcinolone Acetonide for Refractory Diabetic Macular EdemaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The majority of eyes that initially improved with IVTA maintained their gain after 5 years. No new safety concerns were identified. IVTA treatment may be considered in carefully selected cases of impaired vision caused by advanced DME that are unresponsive to other interventions.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)
Source: Ophthalmology - October 1, 2009 Category: Opthalmology Authors: Mark C. Gillies, Judy M. Simpson, Christine Gaston, Grace Hunt, Haipha Ali, Meidong Zhu, Florian Sutter Tags: Original Articles Source Type: journals

ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Tags: This Issue At A Glance Source Type: journals

This Issue At A GlanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study used data from the fourth round of SEE to assess the impact of glaucomatous visual field loss on driving cessation and limitation. Multivariable regression analysis showed that bilateral, but not unilateral, glaucoma patients were more likely to no longer be driving when compared with those without glaucoma. The odds that bilateral glaucoma patients were no longer driving doubled for every 5 decibels (dB) of visual field (VF) worsening in the better eye. The researchers conclude these findings indicate a significant social impact caused by glaucomatous VF loss. Consequently, preventing glaucoma from progressing ...
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Lori Baker Schena, John Kerrison Tags: This Issue At A Glance Source Type: journals

Editorial BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Tags: Frontmatter Source Type: journals

Independent Auditors' Report and Consolidated Financial StatementsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Tags: Academy Financial Statements Source Type: journals

Orbital Cyst: Prenatal DiagnosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an unusual case of prenatally detected primary conjunctival epithelial cyst of the orbit. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Arun D. Singh, Elias I. Traboulsi, Janet Reid, Donna Patno, Jeffrey Chapa, Ricardo Rodriguez, Sabine Iben, Lynn Schoenfield Tags: Letters to the Editor Source Type: journals

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The article by Samarawickrama, Huynh, and Mitchell confirms prior reports describing neuroretinal abnormalities in eyes presumed to be amblyopic. Their findings demonstrate that the availability of new objective quantitative devices, such as magnification corrected retinal imaging and the optical coherence tomography (OCT) instruments that they used, change the context for diagnosing vision impairments in children. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Philip Lempert Tags: Letters to the Editor Source Type: journals

Retinal Structure in AmplyopiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The recent article by Philip Lempert is a welcome contribution to the growing literature on amblyopia, and possible structural differences between amblyopic and normal eyes. The author created a novel numeric description of the neural connectivity of retinal cells, the retinal area to optic disc rim area ratio, and showed that amblyopic eyes had decreased neural connectivity relative to their fellow eyes, which was in turn lower than in normal eyes. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Chameen Samarawickrama, Son C. Huynh, Paul Mitchell Tags: Letters to the Editor Source Type: journals

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We thank Dr. Brown for her interest in our article. The author was right that there was a typographical error in the text of the results. The axial length was 25.16 mm rather than 24.16 mm. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Louis Tong, Wei Han Chua Tags: Letters to the Editor Source Type: journals

Atropine Treatment for MyopiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report provides data through year 3, or 1 year after treatment was discontinued. I would like to discuss an overlooked issue in this and similar trials of myopia “reduction.” (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Sandra M. Brown Tags: Letters to the Editor Source Type: journals

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We thank Cheung et al for their comments on our original article. Cheung and colleagues have made 9 points. We address them in the order they were presented. Cheung et al indicated that the diagnoses of acute angle closure (AAC) were uncertain. In fact, all cases were diagnosed by an ophthalmologist and were confirmed by a fellowship-trained glaucoma specialist. Space constraints did not allow us to document every detail. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Katherine Masselos, Allan Bank, Ian C. Francis Tags: Letters to the Editor Source Type: journals

Angle Closure GlaucomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the case series regarding corneal indentation for early management of acute angle closure glaucoma reported by Masselos et al, the authors concluded that corneal indentation (CI) is an effective first-line treatment of acute angle closure (AAC). It also suggested its failure in lowering intraocular pressure (IOP) indicated failure of laser peripheral iridotomy in subsequent management of AAC. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Janice J.C. Cheung, Jeffrey C.F. Pong, Catherine H.Y. Chan, Jimmy S.M. Lai Tags: Letters to the Editor Source Type: journals

Topical CyclosporineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A successfully performed keratoplasty with a clear corneal graft may fail due to repeated episodes of endothelial rejection, a major cause of graft failure worldwide. Topical cyclosporine-A 2% has been considered a potential therapy for treating and preventing corneal graft rejection. Efficacy has been reported for oral cyclosporine and tacrolimus in high-risk keratoplasty, but potential systemic toxicity may limit their use. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Rajesh Sinha, Sreenivas Vishnu, Namrata Sharma, Rasik B. Vajpayee Tags: Letters to the Editor Source Type: journals

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We would like to thank Dr. Alan N. Carlson for his meticulous analysis of eye-rubbing behavior among keratoconic patients. We did recommend to all our keratoconic patients not to rub their eyes during the first eye examination in an attempt to minimize progression. In addition, we have been treating all our keratoconic patients with ocular allergic signs and symptoms with appropriate medications. However, despite our treatment and advice many patients progressed. (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Paolo Vinciguerra, Elena Albé Tags: Letters to the Editor Source Type: journals

KeratoconusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the article entitled, “Refractive, Topographic, Tomographic, and Aberrometric Analysis of Keratoconic Eyes Undergoing Corneal Cross-Linking,” by Vinciguerra et al, I noted the authors' success in stabilizing the progression of keratoconus (KCN) by strengthening the cornea through collagen cross-linking. Given the increased attention and effort directed toward methods and merits of strengthening the ectatic cornea, I would like to elevate awareness of external mechanical factors that appear to accelerate the progression of KCN. These factors are preventable, yet they frequently escape the clinician's attention. While...
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Alan N. Carlson Tags: Letters to the Editor Source Type: journals

Internet Eye QuestionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Each day tens of millions of people visit internet healthcare websites and forums. Until recently there have been no published ophthalmic studies based on data derived from internet eye forums. In order to try to understand why people visit eye health websites, we are categorizing questions posted at the 2 eyecare forums sponsored by the American Academy of Ophthalmology (AAO) at Medhelp.org (www.medhelp.org). (Source: Ophthalmology)
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: John C. Hagan, Michael J. Kutryb Tags: Letters to the Editor Source Type: journals

Does Eye Muscle Surgery Improve Vision in Patients with Infantile Nystagmus Syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clinical and electrophysiologic data collected for more than 50 years supports the novel hypothesis that eye muscle surgery improves vision and visual function (other than binocularity) in patients with infantile nystagmus syndrome (INS). Infantile nystagmus syndrome, formerly called congenital nystagmus, occurs in approximately 1 in 600 to 1 in 5000 children. Eye muscle operations for nystagmus can be classified into 9 types. The goals of the first 8 are to improve both the nystagmus and anomalous head or eye position, and include moving or removing parts of 1 to 3 muscles or tendons per eye. The ninth operation improves ...
Source: Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Richard W. Hertle Tags: Editorial Source Type: journals

Sentinel Lymph Node Biopsy for Ocular Adnexal Melanoma: Experience in 30 PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Sentinel lymph node biopsy is effective for identifying nodal micrometastasis in patients with ocular adnexal melanoma and provides important prognostic information. The false-negative event rate in our series improved in the last 4 years, most likely because of a better technique and better patient selection for SLNB. We recommend consideration of SLNB for patients with intermediate-thickness ocular adnexal melanoma and those with ulceration.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 22, 2009 Category: Opthalmology Authors: Aaron Savar, Merrick I. Ross, Victor G. Prieto, Doina Ivan, Stella Kim, Bita Esmaeli Tags: Original Articles Source Type: journals

Characteristics of Traumatic Globe Rupture after KeratoplastyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objective: To analyze risk factors of traumatic wound rupture after penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK).Design: Retrospective case series.Participants: A total of 1962 consecutive cases were included.Methods: A review of consecutive patients undergoing either PKP (1776 eyes) or DALK (186 eyes) at 1 regional center between 1998 and 2006 was carried out to determine the incidence of traumatic globe rupture after keratoplasty. Ophthalmic and demographic factors were analyzed. A comparison with previous literature was performed.Main Outcome and Measures: Incidence, causes, and final vis...
Source: Ophthalmology - September 22, 2009 Category: Opthalmology Authors: Motoko Kawashima, Tetsuya Kawakita, Shigeto Shimmura, Kazuo Tsubota, Jun Shimazaki Tags: Original Articles Source Type: journals

Ocular Manifestation in Treated Multibacillary Hansen's DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Patients who have completed treatment for multibacillary HD continue to have significant ocular morbidity. A history of specific eye symptoms can be the basis for referral by field staff.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)
Source: Ophthalmology - September 22, 2009 Category: Opthalmology Authors: Rajul Parikh, Saju Thomas, Jayaprakash Muliyil, Shefali Parikh, Ravi Thomas Tags: Original Articles Source Type: journals

Prevalence of Amblyopia and Strabismus in White and African American Children Aged 6 through 71 Months: The Baltimore Pediatric Eye Disease StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Manifest strabismus affected 1 in 30 white and 1 in 47 African American preschool-aged children. The prevalence of amblyopia was (Source: Ophthalmology)
Source: Ophthalmology - September 16, 2009 Category: Opthalmology Authors: David S. Friedman, Michael X. Repka, Joanne Katz, Lydia Giordano, Josephine Ibironke, Patricia Hawse, James M. Tielsch Tags: Original Articles Source Type: journals

Methotrexate for Ocular Inflammatory DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our data suggest that adding methotrexate to an anti-inflammatory regimen not involving other noncorticosteroid immunosuppressive drugs is moderately effective for management of inflammatory activity and for achieving corticosteroid-sparing objectives, although many months may be required for therapeutic success. Methotrexate was well tolerated by most patients, and seems to convey little risk of serious side effects during treatment.Financial Disclosure(s): The authors have no proprietary or commercial interests in any of the materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 14, 2009 Category: Opthalmology Authors: Sapna Gangaputra, Craig W. Newcomb, Teresa L. Liesegang, R. Oktay Kaçmaz, Douglas A. Jabs, Grace A. Levy-Clarke, Robert B. Nussenblatt, James T. Rosenbaum, Eric B. Suhler, Jennifer E. Thorne, C. Stephen Foster, John H. Kempen, Systemic Immunosuppressive Tags: Original Articles Source Type: journals

Photodynamic Therapy and Intravitreal Triamcinolone for Neovascular Age-Related Macular Degeneration: A Randomized Clinical TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: There was no visual benefit to the addition of intravitreal triamcinolone to VPDT. Combination therapy, however, can reduce the number of VPDT treatments required by subjects who have predominantly classic CNV owing to AMD. This reduced treatment quantity needs to be weighed against potential side effects. (ClinicalTrials.gov number, NCT00148551).Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)
Source: Ophthalmology - September 14, 2009 Category: Opthalmology Authors: David Maberley, Canadian Retinal Trials Group Tags: Original Articles Source Type: journals

The Ice Pack Test in the Differential Diagnosis of Myasthenic DiplopiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The ice pack test demonstrated high specificity and an acceptable sensitivity in the differential diagnosis of myasthenic diplopia. Data from this series suggest that a partial rather than a complete response to the ice pack test may be expected for myasthenic diplopia. Standardization of the method of application of the ice pack is critical for the interpretation of its effect.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Klio I. Chatzistefanou, Tassos Kouris, Evangelos Iliakis, Georgios Piaditis, Georgios Tagaris, Nikolaos Katsikeris, Grigorios Kaltsas, Michael Apostolopoulos Tags: Original Articles Source Type: journals

Lacrimal Excretory System Concretions: Canalicular and Lacrimal SacEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Purpose: To characterize the demographics of patients with dacryolithiasis and to compare patients who have canalicular concretions with patients who have lacrimal sac and duct dacryoliths.Design: Comparative case series study and literature review.Participants: A total of 327 consecutive patients undergoing external dacryocystorhinostomy (DCR) between 1998 and 2008 at the University of Wisconsin-Madison. Fifteen consecutive patients with the diagnosis of canaliculitis during this period were also included.Methods: The charts of all patients were reviewed for age, sex, laterality, duration of symptoms, history of dacryocys...
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Daniel J. Repp, Cat N. Burkat, Mark J. Lucarelli Tags: Original Articles Source Type: journals

Cilial Entropion: Surgical Outcome with a New Modification of the Hotz ProcedureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our modification of the Hotz procedure is based on identifying and dividing the anterior layer of the lower eyelid retractors and reinforcing the skin to the lower border of the inferior tarsal plate and lower eyelid retractors. This is a useful and predictive technique for cilial entropion repair and results in a high success rate.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Hirohiko Kakizaki, Dinesh Selva, Igal Leibovitch Tags: Original Articles Source Type: journals

Malignant Transformation of Congenital Hypertrophy of the Retinal Pigment EpitheliumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Congenital hypertrophy of the retinal pigment epithelium, once considered to be a benign and stationary lesion, may spawn a malignant neoplasm.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Jerry A. Shields, Ralph C. Eagle, Carol L. Shields, Gary C. Brown, Sara E. Lally Tags: Original Articles Source Type: journals

Adjuvant Interferon Therapy for Patients with Uveal Melanoma at High Risk of MetastasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Interferon-alfa-2a has no material influence on survival in patients with choroidal melanoma.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Anne Marie Lane, Kathleen M. Egan, David Harmon, Amy Holbrook, John E. Munzenrider, Evangelos S. Gragoudas Tags: Original Articles Source Type: journals

Congenital Toxoplasmosis in Southeastern Brazil: Results of Early Ophthalmologic Examination of a Large Cohort of NeonatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: A high prevalence of CT was encountered (1/770) with high rates of early retinochoroidal involvement (∼80%) and many active lesions (in ∼50%), indicating a possibly more severe ocular involvement by CT in Brazil than in other parts of the world. The hypotheses of higher parasite virulence and increased individual susceptibility are being currently investigated.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Daniel Vitor Vasconcelos-Santos, Danuza O. Machado Azevedo, Wesley R. Campos, Fernando Oréfice, Gláucia M. Queiroz-Andrade, Éricka V. Machado Carellos, Roberta M. Castro Romanelli, José Nelio Januário, Luciana Macedo Resende, Olindo Assis Martins-Fil Tags: Original Articles Source Type: journals

Blindness in a 25-Year Follow-up of a Population-Based Cohort of Danish Type 1 Diabetic PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Purpose: To assess the long-term incidence of blindness and to evaluate risk factors for blindness in a population-based cohort of type 1 diabetic patients.Design: Retrospective cohort study.Participants: A population-based cohort of 573 type 1 diabetic patients, all of whom participated in a clinical ophthalmologic examination in 1981 and 1982 and were followed up for 25 years.Methods: At the baseline examination in 1981 and 1982, visual acuity, level of retinopathy, maculopathy, hemoglobin A1 (HbA1), proteinuria, smoking habits, and blood pressure were evaluated and related to the subsequent development of blindness. Bli...
Source: Ophthalmology - September 10, 2009 Category: Opthalmology Authors: Jakob Grauslund, Anders Green, Anne Katrin Sjølie Tags: Original Articles Source Type: journals