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[ASAP] Automated Image-Based Color Analysis as an Accessible and Widely Applicable PAT Tool
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00097 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - July 5, 2023 Category: Chemistry Authors: Simon Smolders, Huibo Sheng, Matthew P. Mower, Aditi Potdar, and Jan Dijkmans Source Type: research

[ASAP] Development of Pd-Catalyzed Asymmetric Allylic Alkylation with Low Catalyst Loading for Large-Scale Production of Ethyl ( < italic toggle="yes" > R < /italic > ) ‑1-Allyl-2-oxocyclohexane-1-carboxylate
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00160 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - July 4, 2023 Category: Chemistry Authors: Yongda Zhang, Jada A. H. White, Eugene Chong, Suttipol Radomkit, Yibo Xu, Jing Liu, and Jon C. Lorenz Source Type: research

[ASAP] Poly(dimethylsiloxane)-Based Recyclable Tablet Catalysts Bearing Gold N ‑Heterocyclic Carbene Complexes for Alkyne Hydration Reactions
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00064 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 30, 2023 Category: Chemistry Authors: Zeynep Tunali, Sidal Dagistanli, Sevval Kubalas, and Bengi Ozgun Ozturk Source Type: research

[ASAP] Drug-Linkers in Antibody –Drug Conjugates: Perspective on Current Industry Practices
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00136 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 29, 2023 Category: Chemistry Authors: Paul G. Bulger, David A. Conlon, Russell D. Cink, Lara Fernandez-Cerezo, Qunying Zhang, Srinath Thirumalairajan, Thomas Raglione, Ruiting Liang, Jinsheng Zhou, and Arun Chalgeri ⧫ Source Type: research

[ASAP] Considerations for Starting Material Designation for Drug-Linkers in Antibody –Drug Conjugates
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00140 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 28, 2023 Category: Chemistry Authors: Michael T. Jones, Olivier Dirat, David A. Conlon, Charles Melucci, Kate Schrier, Thomas Raglione, Qunying Zhang, and Paul G. Bulger Source Type: research

[ASAP] Practical Synthesis of Reactive Immuno-PET Linker-Chelator (1 < italic toggle="yes" > R < /italic > ,2 < italic toggle="yes" > R < /italic > ) ‑RESCA-TFP
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00149 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 28, 2023 Category: Chemistry Authors: Nicholas Wong, Eileen Zhao, Jiangyin Bao, Stefan G. Koenig, Carmela Molinaro, Jacob C. Timmerman, Haiming Zhang, C. Gregory Sowell, and Francis Gosselin Source Type: research

[ASAP] Optimized Process and Quality Evaluation for Ketamine Hydrochloride
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00082 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 26, 2023 Category: Chemistry Authors: Bibo Jiang, Haibo Pan, Jiajia Liu, Xiaojie Zhang, Qian Wang, Tao Zhang, and Fuli Zhang Source Type: research

[ASAP] Development of a Scalable Electrophilic Amination Protocol for the Multi-kg Production of 5 ‑Methyl-2-pyridinesulfonamide: A Regulatory Starting Material of Endothelin Receptor Antagonist Clazosentan
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00131 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 23, 2023 Category: Chemistry Authors: Gabriel Scha ̈fer, Tony Fleischer, Matthias Kastner, Reinhard Karge, Qi Huang, Bruce Libang Wu, Jun Tang, and Iris Aiglstorfer Source Type: research

[ASAP] Elevating 1- < italic toggle="yes" > tert < /italic > -Butyl-3-ethylcarbodiimide (TBEC) as a Reagent for Sustainable Peptide Synthesis: Quality Assessment and Minimizing Racemization, Precipitation, and Radical-Induced Side Reactions by TBEC/Oxyma Couplings in an Environmentally Sensible Solvent
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00120 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 23, 2023 Category: Chemistry Authors: Jan Pawlas, Ji-Hyung Choi, Christoph von Bargen, Sheila Maibom-Thomsen, Jon H. Rasmussen, and Olivier Ludemann-Hombourger Source Type: research

[ASAP] Correction to “Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis”
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00138 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 22, 2023 Category: Chemistry Authors: Vijayagopal Gopalsamuthiram, Appasaheb L. Kadam, Jeffrey M. Noble, David R. Snead, Corshai Williams, Timothy F. Jamison, Chris Senanayake, Ajay K. Yadaw, Sarabindu Roy, Gopal Sirasani, B. Frank Gupton, Justina Burns, Daniel W. Cook, Rodger W. Stringham, S Source Type: research

[ASAP] High-Throughput Crystallization Screening Technique with Transmission PXRD Analysis
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00091 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 20, 2023 Category: Chemistry Authors: Victor W. Rosso, Zhiwei Yin, Heba Abourahma, Ariel Furman, Shasad Sharif, Andrew Werneth, Jason M. Stevens, Frederick Roberts, Darpandeep Aulakh, Roger Sommer, and Amy A. Sarjeant Source Type: research

[ASAP] Development of a Trimethylamine-Catalyzed Novel Synthesis of Azoxystrobin
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00033 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 16, 2023 Category: Chemistry Authors: Binglian Yang, Wuping Xue, Baoqing Yu, Huailin Pang, Le Yu, Qingling Wang, and Dianhu Zhu Source Type: research

[ASAP] Energetic Material Synthesis: Scale-up Using a Novel Modular Microflow Reactor Setup
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00398 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 16, 2023 Category: Chemistry Authors: Konstantin Karaghiosoff, Thomas M. Klapo ̈tke, and Maurus B. R. Völkl Source Type: research

[ASAP] Practical and Scalable Method for Manufacturing AZD4604, A Potent and Selective JAK1 Inhibitor
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00077 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 15, 2023 Category: Chemistry Authors: Subhash Pithani, Carl-Johan Aurell, Marika Lindhagen, Michael Nunn, Kristina Berggren, and Hans Emtena ̈s Source Type: research

[ASAP] Thermodynamic and Kinetic Mechanism of the Phase Transition from Aztreonam Dihydrate to Anhydrates
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00046 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - June 14, 2023 Category: Chemistry Authors: Ziwei Feng, Beiqian Tian, Guangyan Li, Li Wang, Na Wang, Xin Huang, Lina Zhou, Shuangxi Li, Hao Wang, Ting Wang, and Hongxun Hao Source Type: research