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(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

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(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

Editorial Boardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

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(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

Correctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Due to a printer error, the figure in a letter to the Editor for the June 2008 issue of Otolaryngology-Head and Neck Surgery was distorted. Della Santina CC. Cochleostomy placement and vestibular injury. Otolaryngol Head Neck Surg. 2008 Jun;138(6):812-3. Please see the correct here. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Corrections Source Type: journals

Correctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The following article, which also ran in the April 2007 issue of Otolaryngology-Head and Neck Surgery, contained the same typographical error noted in the previous correction. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Corrections Source Type: journals

Correctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The following article, which ran in the April 2007 issue of Otolaryngology-Head and Neck Surgery, contained an error. “Biofilm formation in cochlear implants with cochlear drug delivery channels in an in vitro model” by TA Johnson, KA Loeffler, RA Burne, CN Jolly, and PJ Antonelli, pages 577-582. Under the Materials and Methods section, page 579, Quantitative Microbiology subheading, “… and plating 100 mL on 5% sheep blood agar.” should have been “… and plating 100 μL on 5% sheep blood agar.” (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Tags: Corrections Source Type: journals

Modification of the mandibular genial osteotomy for “drop down” access to the base of the tongueemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe our modification of the pedicled genial osteotomy during mandibular lingual releasing access. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Bagrat Lalabekyan, Colin Hopper, Paul Norris, Francis Vaz, Nicholas Kalavrezos Tags: Clinical Techniques and Technology Source Type: journals

Prevention of unplanned pharyngocutaneous fistula in salvage laryngectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present the formula used by the senior author at the Downstate Medical Center and affiliated hospitals in his last 11 cases, in which healing occurred without unplanned fistula formation, and length of stay was 10 days. Prior to the introduction of the formula, out of nine salvage laryngectomies (historical controls), the same surgeon had six cases of wound dehiscence and unplanned occurrence of a pharyngocutaneous fistula (67%). In these nine cases, one or more components of the formula were not used. Results using this fistula reduction formula appear superior to other reported attempts at fistula rate reduction and t...
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Krishnamurthi Sundaram, Jared M. Wasserman Tags: Clinical Techniques and Technology Source Type: journals

Additional diagnostic value of 18F-FDG PET-CT in detecting retropharyngeal nodal metastasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: 18F-FDG PET-CT, when used in combination with CT/MRI, increases diagnostic efficacy in the detection of RPLN metastases and may therefore be useful in screening high-risk patients. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Hyung Ro Chu, Jin Hwan Kim, Dae Young Yoon, Hee Sung Hwang, Young-Soo Rho Tags: Head and Neck Surgery Source Type: journals

2D-DIGE proteomic characterization of head and neck squamous cell carcinomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Downregulation of cornulin is a prominent feature of the molecular signature of HNSCC identified by comparative proteomics. Cornulin may represent a link between HNSCC and other pathologies arising in stratified squamous epithelium. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Mark A. Merkley, Paul M. Weinberger, Lana L. Jackson, Robert H. Podolsky, Jeffrey R. Lee, William S. Dynan Tags: Head and Neck Surgery Source Type: journals

Volume and distances of the maxillary sinus in craniofacial deformities with midfacial hypoplasiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: There were differences in the structure of the maxillary sinuses among patients with different CFDs. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Seung Yong Song, Jong Won Hong, Tai Suk Roh, Yong Oock Kim, Deok Won Kim, Beyoung Yun Park Tags: Sinonasal Disorders Source Type: journals

In vitro testing of tympanostomy tube occlusionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The in vitro TT chamber simulates the in vivo environment and yields results consistent with in vivo observations. This model system may allow for rapid prototyping and evaluation of new TTs that may be less vulnerable to occlusion. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Ethan G. Sherman, Patrick J. Antonelli, Roger Tran-Son-Tay Tags: Pediatric Otolaryngology Source Type: journals

Complications/adverse effects of maxillomandibular advancement for the treatment of OSA in regard to outcomeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Maxillomandibular advancement can induce local adverse effects and cosmetic changes, but they seem to be considered as secondary to the patients according to the surgical outcome. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Marc B. Blumen, Isabelle Buchet, Pierre Meulien, Chantal Hausser Hauw, Helene Neveu, Frédéric Chabolle Tags: Sleep Medicine Source Type: journals

Direct drug application to the round window: A comparative study of ototoxicity in ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Situating a sponge soaked in kanamycin and furosemide on the round window membrane through the ventral approach is a reliable method to provoke local ototoxicity in rats. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Silvia Murillo-Cuesta, Fernando García-Alcántara, Elena Vacas, Jon Alexander Sistiaga, Guadalupe Camarero, Isabel Varela-Nieto, Teresa Rivera Tags: Otology and Neurotology Source Type: journals

Hearing outcomes of daily intratympanic dexamethasone alone as a primary treatment modality for ISSHLemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: IT dexamethasone might be a good primary treatment method for ISSHL; but, for the management of ISSHL, we should keep in mind the differences in hearing outcomes with regard to frequency. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Seok Min Hong, Chan Hum Park, Jun Ho Lee Tags: Otology and Neurotology Source Type: journals

Biofilm presence in humans with chronic suppurative otitis mediaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Biofilms were statistically more common in patients with CSOM compared with control patients. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Michael Robert Lee, Karen Sue Pawlowski, Amber Luong, Alexis Dorian Furze, Peter Sargent Roland Tags: Otology and Neurotology Source Type: journals

Unexpected consequences of proton pump inhibitor useemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Proton pump inhibitors (PPIs) are among the most widely prescribed classes of medications for gastroesophageal and laryngopharyngeal reflux diseases. There is emerging evidence that the pathogenesis of disease in laryngeal mucosa is not just related to refluxed acid, but also the presence of pepsin and acidic microenvironments. The widespread use of PPIs is also calling into question potential complications of PPI use. This commentary expands upon these issues with other potential unexpected consequences, and considers the importance of determining a proper approach to patient management. (Source: Otolaryngology ...
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Kenneth W. Altman, James A. Radosevich Tags: Commentary Source Type: journals

Pepsin as a causal agent of inflammation during nonacidic refluxemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Exposure of hypopharyngeal cells to pepsin in a nonacidic environment induces the expression of several pro-inflammatory cytokines and receptors, including those known to be involved in inflammation of esophageal epithelium in response to reflux and which contribute to the pathophysiology of reflux esophagitis. These data indicate that refluxed pepsin may contribute to laryngeal inflammation associated with nonacidic gastric reflux, including that experienced by patients despite maximal acid suppression therapy. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 27, 2009 Category: ENT & OMF Authors: Tina L. Samuels, Nikki Johnston Tags: Laryngology and Neurolaryngology Source Type: journals

Oropharyngeal flora changes after tonsillectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Oropharyngeal anaerobic bacterial flora decreases after tonsillectomy in recurrent tonsillitis patients. The isolation rate for bacteria of the normal flora and potentially pathogenic bacteria does not change. Tonsils with recurrent infections may become a nidus for anaerobic bacteria. In patients with chronic recurrent tonsillitis, tonsillectomy may help change anaerobic bacterial oropharyngeal flora to the normal flora found in healthy individuals. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 1, 2009 Category: ENT & OMF Authors: Emin Karaman, Ozgun Enver, Yalcin Alimoglu, Nevriye Gonullu, Hrisi Bahar, Muzeyyen Mamal Torun, Huseyin Isildak Tags: Pediatric Otolaryngology Source Type: journals

Construct validity of a simulator for myringotomy with ventilation tube insertionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our model is a valid platform for simulating myringotomy with ventilation tube insertion. The model discriminates novices from non-novices, has a learning curve, and is perceived to be a valuable and realistic teaching tool by users. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 1, 2009 Category: ENT & OMF Authors: Peter G. Volsky, Brian B. Hughley, Shayn M. Peirce, Bradley W. Kesser Tags: Pediatric Otolaryngology Source Type: journals

Clinical efficacy of initial intratympanic steroid treatment on sudden sensorineural hearing loss with diabetesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: ITSI is as effective as systemic steroid treatment for sudden SNHL patients with diabetes and it can avoid undesirable side effects. Therefore, we consider ITSI to be a more reasonable alternative as an initial treatment for sudden SNHL patients with diabetes. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 1, 2009 Category: ENT & OMF Authors: Chi-Sung Han, Jong-Ryul Park, Sung-Hyun Boo, Joon-Man Jo, Kyung-Won Park, Won-Yong Lee, Joong-Gi Ahn, Myung-Koo Kang, Byung-Gun Park, Hyun Lee Tags: Otology and Neurotology Source Type: journals

Readability analysis of patient information on the American Academy of Otolaryngology–Head and Neck Surgery websiteemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This analysis has shown that the average reading level for each article on the AAO–HNS site was higher than the recommended sixth grade reading level. Although the AAO–HNS site is written at a higher level than that suggested for the general public, it is important to realize that readability is just one consideration in the evaluation of OHI comprehension. Physicians need to be cognizant of their patients' ability to read and comprehend written information and tailor their educational material appropriately. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - October 1, 2009 Category: ENT & OMF Authors: Jewel Greywoode, Eric Bluman, Joseph Spiegel, Maurits Boon Tags: General Otolaryngology Source Type: journals

Going to the next level: Health care's evolving expectations for evidenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Rhinologic literature has historically relied on lower levels of evidence to make prescriptive recommendations for use of new technology and procedures. However, as the medical profession has moved to embrace the principles of evidence-based medicine, expectations for minimum standards of evidence have risen. The resulting high-quality efficacy outcomes data have become the linchpin of informed decision making by physicians, payers, and health care systems. While many challenges remain in this transition to higher evidence expectations, none are insurmountable. It has become the responsibility of the organized me...
Source: Otolaryngology - Head and Neck Surgery - October 1, 2009 Category: ENT & OMF Authors: Bradley F. Marple, Scott P. Stringer, Pete S. Batra, Neil Bhattacharyya, Alexander G. Chiu, Martin J. Citardi, Joseph K. Han, Robert C. Kern, Todd T. Kingdom, Andrew P. Lane, Richard R. Orlandi, Matthew W. Ryan, Brent A. Senior, Michael G. Stewart, Task F Tags: Commentary Source Type: journals

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(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

Society Pageemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

Editorial Boardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

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(Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Tags: Frontmatter Source Type: journals

Toward a multidisciplinary approach to the treatment of obstructive sleep apnea in the obese childemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Costa and Mitchell concluded that adenotonsillectomy cured less than half of obese children with obstructive sleep apnea (OSA). Although the authors recommend studies on the efficacy of additional treatments, no implications for daily practice were given. I would therefore like to suggest some practical conclusions. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Stijn Verhulst Tags: Letter to the Editor Source Type: journals

Local steroid injections in the management of skin growth over the abutment in Baha patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Bone-anchored cochlear stimulator (Baha system; Cochlear Bone Anchored Solutions, AB Mölnlycke, Göteborg, Sweden) has offered safe and successful rehabilitation for patients with various types of hearing loss. Major complications are rare, but the percutaneous nature of the Baha system predisposes the surgical site for soft tissue complications after surgery. Skin overgrowth around the abutment is one example and has been reported in a few series, with a frequency of five to 23 percent. Patients presenting with skin overgrowth over the abutment are usually treated conservatively with topical and oral antibiotics in addit...
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Soha N. Ghossaini, Jaclyn B. Spitzer Tags: Clinical Techniques and Technology Source Type: journals

Visual analog scale (VAS) and nasal obstruction in persistent allergic rhinitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The use of VAS for assessing the nasal obstruction appears clinically relevant in that it allows, with good reliability, the quantification of this symptom in the absence of rhinomanometry. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Giorgio Ciprandi, Francesco Mora, Michele Cassano, Anna Maria Gallina, Renzo Mora Tags: Short Scientific Communication Source Type: journals

Voice outcomes following repeated surgical resection of laryngeal papillomata in childrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: This is the first study to use perceptual and objective acoustic evaluations to compare voice outcomes following microdebrider or CO2 laser treatment of JORRP. The results of this study suggest that treatment with the microdebrider results in a better immediate and early postoperative voice outcome. Moreover, the data demonstrate a correlation of worsening voice quality with increased exposure to the CO2 laser. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Theresa Holler, Jennifer Allegro, Neil K. Chadha, Michael Hawkes, Robert V. Harrison, Vito Forte, Paolo Campisi Tags: Pediatric Otolaryngology Source Type: journals

Proposal for staging airway hemangiomasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: This method of airway hemangioma staging may be applicable to treatment planning and used to measure treatment outcomes. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Jonathan A. Perkins, Eunice Y. Chen, Fredric A. Hoffer, Scott C. Manning Tags: Pediatric Otolaryngology Source Type: journals

Topical clindamycin in post-adenotonsillectomy analgesia in children: A double-blind, randomized clinical trialemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The use of topical clindamycin was beneficial in reducing pain on the first postoperative day, without effect on subsequent days. Future investigations could examine the use of topical clindamycin not only in the first 12 hours but also during five days of follow-up. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Mauricio Schreiner Miura, Catia Saleh, Marina de Andrade, Melina Assmann, Lucélia Hernandes Lima, José Faibes Lubianca Neto Tags: Pediatric Otolaryngology Source Type: journals

Mutation analysis of SLC26A4 in mainland Chinese patients with enlarged vestibular aqueductemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our data confirm the high prevalence of SLC26A4 mutations in Chinese patients with SNHL and EVA. We could not establish any relationship between genotype and phenotype. However, the high incidence of asymmetric, progressive, and fluctuating hearing loss found in the current study indicates that patients with those features should be routinely screened for SLC26A4 mutation in addition to diagnosis of EVA using CT or MRI. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Samuel Reyes, Guojian Wang, Xiaomei Ouyang, Bing Han, Li Lin Du, Hui Jun Yuan, Denise Yan, Pu Dai, Xue-Zhong Liu Tags: Otology Source Type: journals

Comparison of LigaSure vessel sealing system, harmonic scalpel, and conventional hemostasis in total thyroidectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Total thyroidectomy using the harmonic scalpel was the fastest procedure because it was bloodless, and hemostasis and sectioning were controlled with a single instrument; it was, therefore, the most inexpensive procedure because of the reduction of operative time and staff cost. The operative safety was similar for all three procedures. In our series, the harmonic scalpel and the LVSS caused less pain than the conventional hemostasis. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Yoann Pons, Jérome Gauthier, Elsa Ukkola-Pons, Philippe Clément, Eric Roguet, Jean-Luc Poncet, Claude Conessa Tags: Endocrine Surgery Source Type: journals

Progesterone receptors identified in vascular malformations of the head and neckemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our data suggest that PR, but not ER, is expressed in AVMs, VMs, and LMs of the head and neck. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Landon J. Duyka, Chun Y. Fan, Jean M. Coviello-Malle, Lisa Buckmiller, James Y. Suen Tags: Head and Neck Surgery Source Type: journals

Increased microsatellite instability and epigenetic inactivation of the hMLH1 gene in head and neck squamous cell carcinomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Promoter hypermethylation of the hMLH1 gene could be detected early in head and neck squamous carcinogenesis and may be associated with increased MSI and poor survival in HNSCC. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Chunlai Zuo, Haihong Zhang, Horace J. Spencer, Emre Vural, James Y. Suen, Steven A. Schichman, Bruce R. Smoller, Mimi S. Kokoska, Chun-Yang Fan Tags: Head and Neck Surgery Source Type: journals

Prognostic relevance of CD105-assessed microvessel density in laryngeal carcinomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: To examine immunohistochemical expression of CD105 among patients with laryngeal cancer and investigate the prognostic significance of CD105-assessed microvessel density (MVD).Study Design: Cross-sectional study.Setting: University hospital.Subjects and Methods: The study comprised 80 patients with laryngeal squamous cell carcinoma who underwent complete excision. Clinicopathological data were collected retrospectively. Immunohistochemical analysis was performed with CD105 (endoglin) antibody. Positive-stained microvessels for CD105 were counted on hot spots of tumors at ×200 magnification.Results: Av...
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Elvir Zvrko, Anton Mikic, Ljiljana Vuckovic, Vojko Djukic, Milan Knezevic Tags: Head and Neck Surgery Source Type: journals

Planned neck dissection following primary chemoradiation for advanced-stage head and neck canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Planned neck dissection in the setting of advanced neck disease following chemoradiation should remain an important consideration when counseling patients presenting with advanced cervical metastasis from squamous cell head and neck cancer. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Peter R. Sabatini, Yadranko Ducic Tags: Head and Neck Surgery Source Type: journals

HER2 expression predicts improved survival in patients with cervical node–positive head and neck squamous cell carcinomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: HER2 may be associated with longer survival in node-positive patients with HNSCC. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Gary M. Tse, Kwok Hung Yu, Anthony W.H. Chan, Ann D. King, George G. Chen, Ka-Tak Wong, Raymond K.Y. Tsang, Amy B.W. Chan Tags: Head and Neck Surgery Source Type: journals

Role of acidic mammalian chitinase and chitotriosidase in nasal polypsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: AMCase and ChT may be important mediators in the pathogenesis of nasal polyps. Nasal polyps appear to have elevated levels of chitinases, and the presence or growth of chitin-containing pathogens might enhance chitinase expression, resulting in nasal polyp formation and growth in susceptible individuals. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Seong Kook Park, Hong Wook Cho, Kyung Wook Heo, Dae Young Hur, Hyun-Kyung Lee Tags: Sinonasal Disorders Source Type: journals

Relationship between clinical measures and histopathologic findings in chronic rhinosinusitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Mucosal eosinophilia correlates with objective disease severity as defined by CT, endoscopy, and SIT scores. Although other histologic markers of inflammation are present, none show similar correlations. The presence of mucosal eosinophils does not correlate with quality-of-life scores. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Zachary M. Soler, David A. Sauer, Jess Mace, Timothy L. Smith Tags: Sinonasal Disorders Source Type: journals

Biofilms correlate with TH1 inflammation in the sinonasal tissue of patients with chronic rhinosinusitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Sinonasal bacterial biofilms correlate to a TH1 skewed local but not systemic inflammatory response in CRS. This difference is abrogated by the use of oral steroids. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Adrianna M. Hekiert, Jennifer M. Kofonow, Laurel Doghramji, David W. Kennedy, Alexander G. Chiu, James N. Palmer, Jeffery G. Leid, Noam A. Cohen Tags: Sinonasal Disorders Source Type: journals

Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The presence of AR may enhance the expression of MMP-9, MMP-2, and TIMP-1 associated with airway remodeling in nasal polyposis. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Hyun-Woo Shin, Doo Hee Han, Yune Sung Lim, Hye Jung Kim, Dong-Young Kim, Chul Hee Lee, Yang-Gi Min, Chae-Seo Rhee Tags: Allergy Source Type: journals

Extracts from The Cochrane Library: Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: The “Cochrane Corner” is a quarterly section in the Journal that highlights systematic reviews relevant to otolaryngology–head and neck surgery, with invited commentary to aid clinical decision making. This installment features a Cochrane Review entitled “Erythropoietin as an adjuvant treatment with (chemo) radiation therapy for head and neck cancer,” which concludes that erythropoietin should not be administered as an addition to radiation therapy outside the experimental setting. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Martin J. Burton, Daniel G. Deschler, Richard M. Rosenfeld Tags: The Cochrane Corner Source Type: journals

Reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
As research accumulates at an astounding pace, the inevitable question arises: “What does it all mean?” Clinicians and consumers often turn to review articles for an answer, seeking the advice and perspective of seasoned experts. This publishing genre has gradually changed from simple review of research to research in itself, much to the chagrin of authors seeking easy fame in publishing. I hope you find the saga of one such author instructive. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 28, 2009 Category: ENT & OMF Authors: Richard M. Rosenfeld Tags: Editorial Source Type: journals

Anatomical variations of the spinal accessory nerve and its relevance to level IIb lymph nodesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our results may help to minimize the incidence of injuring the SAN in the upper neck during ND. Neck level IIb would contain more LNs if the course of the nerve leans toward the ventral side. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 18, 2009 Category: ENT & OMF Authors: Sang Hyuk Lee, Jong Kyu Lee, Sung Min Jin, Jin Hwan Kim, Il Seok Park, Hyung Ro Chu, Hwoe Young Ahn, Young Soo Rho Tags: Head and Neck Surgery Source Type: journals

Penetrating facial injury from a wooden chopstickemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 46-year-old man presented to the emergency room with a stab injury inflicted one hour earlier by a wooden chopstick during a quarrel with his friends. He complained of throat pain radiating to the left ear and difficulty swallowing. Neurological examination on arrival revealed no deficit. A 1-cm-long skin laceration was present in the left preauricular area (). On inspection of the throat, part of the wooden chopstick protruding through the posterior oropharyngeal wall was visible. Neck CT revealed a low-density object extending from the preauricular skin to the oropharynx (). The object pierced the skin and passed throu...
Source: Otolaryngology - Head and Neck Surgery - September 7, 2009 Category: ENT & OMF Authors: Min-Su Kim, Jeong Hun Jang, Min-Hyun Park Tags: Clinical Photographs Source Type: journals

Postoperative monitoring in free tissue transfer patients: Effective use of nursing and resident staffemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: A monitoring protocol utilizing trained nursing staff has no detrimental effect on free tissue transfer outcomes. This may be used to optimize resident time within the current duty-hour restrictions. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - September 7, 2009 Category: ENT & OMF Authors: Ryan S. Jackson, Ronald J. Walker, Mark A. Varvares, Michael J. Odell Tags: Facial Plastic and Reconstructive Surgery Source Type: journals