Relationships between the Spinal Dural Pulsations and the Short-Term Efficacy of Lumbar Epidural Steroid Injection
CONCLUSION: The ESI was effective in patients with spinal stenosis in short-term follow-up. Dural pulsation of the spinal cord was a positive predictive factor for the ESI effect, but the grade of spinal stenosis severity had no effect on the effectiveness of ESI.PMID:38528984 | PMC:PMC10963105 | DOI:10.1155/2024/1824269 (Source: Pain Research and Management)
Source: Pain Research and Management - March 26, 2024 Category: Anesthesiology Authors: Chan Hong Park Sang Ho Lee Source Type: research

Relationships between the Spinal Dural Pulsations and the Short-Term Efficacy of Lumbar Epidural Steroid Injection
CONCLUSION: The ESI was effective in patients with spinal stenosis in short-term follow-up. Dural pulsation of the spinal cord was a positive predictive factor for the ESI effect, but the grade of spinal stenosis severity had no effect on the effectiveness of ESI.PMID:38528984 | PMC:PMC10963105 | DOI:10.1155/2024/1824269 (Source: Pain Research and Management)
Source: Pain Research and Management - March 26, 2024 Category: Anesthesiology Authors: Chan Hong Park Sang Ho Lee Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research

NGF Signaling Exacerbates KOA Peripheral Hyperalgesia via the Increased TRPV1-Labeled Synovial Sensory Innervation in KOA Rats
CONCLUSION: This study showed the activation of the NGF/TrKA signaling pathway in KOA promoted the release of pain mediators, increased the innervation of sensory nerve fibers in the synovium, and worsened peripheral hyperalgesia. It also showed increased TRPV1 positive sensory innervation in KOA was mediated by NGF/TrKA signaling and exacerbated peripheral hyperalgesia.PMID:38410126 | PMC:PMC10896652 | DOI:10.1155/2024/1552594 (Source: Pain Research and Management)
Source: Pain Research and Management - February 27, 2024 Category: Anesthesiology Authors: Zixiu Liu Mingchao Li Li Zhang Xiaoqing Shi Taiyang Liao Lishi Jie Likai Yu Peimin Wang Source Type: research