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C3 contributes to the cross-protective immunity induced by Babesia gibsoni phosphoriboprotein P0 against a lethal B. rodhaini infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have studied the impact of complement component 3 (C3) deficiency on the progression of lethal Babesia rodhaini infection in immune mice. A B. gibsoni ribosomal phosphoprotein P0 (BgP0) previously reported to be a cross-protective antigen against Babesia infection was used to immunize C57BL/6 wild-type (WT) and C3-deficient (C3[ndash]/[ndash]) mice. Test mice were immunized intraperitoneally (i.p.) with recombinant BgP0 (rBgP0), while controls either were immunized with PBS or did not receive any immunization. Following the immunization regime, test WT mice induced a specifically strong humoral response consisting of mi...
Source: Parasite Immunology - September 10, 2008 Category: Parasitology Authors: M. A. TERKAWI, G. ZHANG, H. JIA, G. ABOGE, Y. K. GOO, Y. NISHIKAWA, N. YOKOYAMA, I. IGARASHI, S. I. KAWAZU, K. FUJISAKI, X. XUAN Source Type: journals

Inflammation and structural changes of splenic lymphoid tissue in visceral leishmaniasis: A study on naturally infected dogsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to identify splenic immuno-inflammatory patterns associated with natural infection by Leishmania chagasi. Spleen samples were obtained from 72 stray dogs from an endemic area of visceral leishmaniasis. The animals were grouped into four categories as follows: (i) potentially resistant to visceral leishmaniasis, with a positive leishmanin skin test result, and negative splenic culture for Leishmania parasites (ii) potentially susceptible to visceral leishmaniasis, with a negative leishmanin skin test and positive splenic culture for Leishmania (iii) infected with undefined susceptibility status, wi...
Source: Parasite Immunology - August 6, 2008 Category: Parasitology Authors: C. C. SANTANA, J. VASSALLO, L. A. R. DE FREITAS, G. G. S. OLIVEIRA, L. C. PONTES-DE-CARVALHO, W. L. C. DOS-SANTOS Source Type: journals

Control of pathogenic CD8+ T cell migration to the brain by IFN-γ during experimental cerebral malariaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Previous studies have shown that IFN-[gamma] is essential for the pathogenesis of cerebral malaria (CM) induced by Plasmodium berghei ANKA (PbA) in mice. However, the exact role of IFN-[gamma] in the pathway (s) leading to CM has not yet been described. Here, we used 129P2Sv/ev mice which develop CM between 7 and 14 days post-infection with PbA. In this strain, both CD4+ and CD8+ T cells were involved in the effector phase of CM. When 129P2Sv/ev mice deficient in the IFN-[gamma] receptor [alpha] chain (IFN-[gamma]R1) were infected with PbA, CM did not occur. Migration of leucocytes to the brain at the time of CM was observ...
Source: Parasite Immunology - July 28, 2008 Category: Parasitology Authors: E. BELNOUE, S. M. POTTER, D. S. ROSA, M. MAUDUIT, A. C. GRÜNER, M. KAYIBANDA, A. J. MITCHELL, N. H. HUNT, L. RÉNIA Source Type: journals

Complement-mediated killing of Philasterides dicentrarchi (Ciliophora) by turbot serum: relative importance of alternative and classical pathwaysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study was carried out to elucidate the in vitro killing activity of turbot complement and specific antibodies against the ciliate parasite Philasterides dicentrarchi. Fresh serum from nonimmunized fish showed a moderate ability to kill the parasite, which indicates that P. dicentrarchi is able to activate the alternative complement pathway (ACP). Fresh serum from immunized fish, which contained high levels of specific antibodies, showed greater killing activity. Heat-inactivated serum, with or without antibodies, and antibodies alone did not have any effect on parasite viability, which indicates that serum main...
Source: Parasite Immunology - July 28, 2008 Category: Parasitology Authors: J. LEIRO, M. C. PIAZZÓN, B. BUDIÑO, M. L. SANMARTÍN, J. LAMAS Source Type: journals

Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study finds negligible difference in the cellular and humoral immune response to T. muris adult and third stage larva(e) (L3) ES during a primary T. muris infection, but identifies high molecular weight proteins in both adult and L3 ES as potential vaccine candidates.
Source: Parasite Immunology - July 13, 2008 Category: Parasitology Authors: H. DIXON, C. E. JOHNSTON, K. J. ELSE Source Type: journals

Lymphocyte hyporesponsiveness during filarial nematode infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A frequently observed feature of active infection with filarial nematodes is the presence of lymphocytes in the bloodstream that have impaired responsiveness to antigen. It is generally accepted that such a defect in lymphocyte function could contribute to the failure of the immune system to eliminate filarial nematodes. For this reason, understanding the mechanism underlying lymphocyte 'hyporesponsiveness' is an important goal for immunologists who study filarial nematodes. Thus, although there has long been an interest in answering questions such as what stage(s) of the nematode causes hyporesponsiveness, more recently, ...
Source: Parasite Immunology - June 28, 2008 Category: Parasitology Authors: W. HARNETT, M. M. HARNETT Source Type: journals

Protective immunity induced by daily bites from irradiated mosquitoes infected with Plasmodium yoeliiEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Individuals in malaria endemic regions do not develop fully protective immune responses against Plasmodium liver stage infections. In high transmission areas, individuals can be exposed to more than two infective mosquito bites daily. Their exposure to Plasmodium sporozoites, therefore, is in the form of small and frequent doses. This is very different from individuals studied in controlled immunization trials where the delivery of large numbers of radiation-attenuated sporozoites in a limited number of doses can induce sterile protective immunity. Using irradiated mosquitoes infected with Plasmodium yoelii 17XNL, we teste...
Source: Parasite Immunology - June 28, 2008 Category: Parasitology Authors: K. A. WONG, A. ZHOU, A. RODRIGUEZ Source Type: journals

Protective immunity induced by daily bites from irradiated mosquitoes infected with Plasmodium yoeliiEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Individuals in malaria endemic regions do not develop fully protective immune responses against Plasmodium liver stage infections. In high transmission areas, individuals can be exposed to more than two infective mosquito bites daily. Their ...
Source: Parasite Immunology - June 20, 2008 Category: Parasitology Tags: article Source Type: journals

Lymphocyte hyporesponsiveness during filarial nematode infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY A frequently observed feature of active infection with filarial nematodes is the presence of lymphocytes in the bloodstream that have impaired responsiveness to antigen. It is generally accepted that such a defect in lymphocyte function could ...
Source: Parasite Immunology - June 19, 2008 Category: Parasitology Tags: article Source Type: journals

Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Trichuriasis, caused by the whipworm Trichuris trichiura, is endemic in tropical and subtropical areas, affecting approximately 1 billion people. Child anthelminthic treatment programmes are being implemented but repeated treatments are costly, ...
Source: Parasite Immunology - June 19, 2008 Category: Parasitology Tags: article Source Type: journals

The predicted impact of immunosuppression upon population age–intensity profiles for schistosomiasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The slow development of acquired immunity is thought to be responsible for the characteristic convex age–intensity curve seen in human schistosome infection, which peaks earlier in more heavily infected populations (this is described as a peak ...
Source: Parasite Immunology - June 3, 2008 Category: Parasitology Tags: article Source Type: journals

C3 contributes to the cross-protective immunity induced by Babesia gibsoni phosphoriboprotein P0 against a lethal B. rodhaini infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 6-7, Page 365-370, June/July 2008. SUMMARY We have studied the impact of complement component 3 (C3) deficiency on the progression of lethal Babesia rodhaini infection in immune mice. A B. gibsoni ribosomal phosphoprotein P0 (BgP0) previously reported to be a cross-protective antigen ...
Source: Parasite Immunology - June 3, 2008 Category: Parasitology Tags: article Source Type: journals

Mast cells are activated by Leishmania mexicana LPG and regulate the disease outcome depending on the genetic background of the hostEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a comparative analysis of TLR2 membrane expression, TNF-α, IL-10 and MIP-1α production, and granule release of bone marrow-derived mast cells (BMMCs) ...
Source: Parasite Immunology - May 28, 2008 Category: Parasitology Tags: article Source Type: journals

Toxocara canis larval excretory/secretory proteins impair eosinophil-dependent resistance of mice to Nippostrongylus brasiliensisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Survival of parasitic helminths within a host requires immune evasion and excretory/secretory (ES) proteins may contribute to this process. Eosinophils are important effector cells in immunity of mice to the nematode Nippostrongylus brasiliensis ...
Source: Parasite Immunology - May 28, 2008 Category: Parasitology Tags: article Source Type: journals

Towards a differential definition of atopy: Anisakis simplex and the relationship between parasites and arthropods in respiratory allergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Protective as well as enhancing effects of parasite infections on allergic disease have been postulated. Previous studies on this relationship focused frequently on skin test reactivity against aeroallergens, being house dust mites (HDM) the main ...
Source: Parasite Immunology - May 26, 2008 Category: Parasitology Tags: article Source Type: journals

Demonstration of strain-specific CD8 T cell responses to Theileria annulataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The present study set out to examine the nature and specificity of the bovine CD8 T cell response at the clonal level in a group of eight animals immunized with a cloned population of Theileria annulata. The results demonstrated that immunized ...
Source: Parasite Immunology - May 22, 2008 Category: Parasitology Tags: article Source Type: journals

Trichomonas vaginalis-induced neutrophil apoptosis causes anti-inflammatory cytokine production by human monocyte-derived macrophagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Neutrophils are the predominant inflammatory cells found in the vaginal discharge of patients with a Trichomonas vaginalis infection. Neutrophils have a shorter life span than other leucocytes. Our previous study indicated that live T. vaginalis ...
Source: Parasite Immunology - May 20, 2008 Category: Parasitology Tags: article Source Type: journals

Selenium supplementation enhances the protective response to Toxocara canis larvae in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The effect of oral and intraperitoneal supply of sodium selenite on the immune response to, and the course of T. canis larvae infection in mice were determined. The number of worms in the host tissue was reduced but the migratory route of larvae ...
Source: Parasite Immunology - May 15, 2008 Category: Parasitology Tags: article Source Type: journals

Distinct pattern of class and subclass antibodies in immune complexes of children with cerebral malaria and severe malarial anaemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Plasmodium falciparum infection can lead to deadly complications such as severe malaria-associated anaemia (SMA) and cerebral malaria (CM). Children with severe malaria have elevated levels of circulating immune complexes (ICs). To further ...
Source: Parasite Immunology - May 7, 2008 Category: Parasitology Tags: article Source Type: journals

Elevated levels of IgG3 and IgG4 subclass in paediatric cases of kala azarEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Visceral leishmaniasis (VL) or Kala azar (KA) is a systemic disease caused by the parasites of the Leishmania donovani complex. Control measures rely on treatment with antileishmanial agents, however, fraught with problems such as toxicity or ...
Source: Parasite Immunology - May 7, 2008 Category: Parasitology Tags: article Source Type: journals

Characterization of bovine lymphocytes stimulated in vitro by Dictyocaulus viviparus homogenateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Adult Dictyocaulus viviparus homogenate induced proliferation of lymphocytes from naïve cattle. We characterized the responding cells by carboxyfluorescein diacetate succinimidyl ester (CFSE) loading, for detection of proliferation, and antibody ...
Source: Parasite Immunology - April 28, 2008 Category: Parasitology Tags: article Source Type: journals

Processing of the circumsporozoite protein in infected hepatocytes is not dependent on aspartic proteasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY CD8+ T cells play a major role in the protective immune response against the liver stage of malaria. It was previously shown that the circumsporozoite protein (CSP) is processed and presented to specific T cells by both traversed and infected ...
Source: Parasite Immunology - April 28, 2008 Category: Parasitology Tags: article Source Type: journals

Resistance of the Echinococcus granulosus cyst wall to complement activation: analysis of the role of InsP6 depositsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The larva of the cestode Echinococcus granulosus (hydatid cyst) is protected by the acellular laminated layer (LL). The mechanisms that make this thick coat a poor activator of host complement are incompletely understood. The structure binds, ...
Source: Parasite Immunology - April 28, 2008 Category: Parasitology Tags: article Source Type: journals

Cellular immune responses to recombinant Plasmodium vivax tryptophan-rich antigen (PvTRAg) among individuals exposed to vivax malariaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Plasmodium vivax, the most widespread species of human malaria parasite responsible for 70–80 million cases each year requires a vaccine. In recent years, many potential vaccine candidate antigens have been identified from P. vivax including ...
Source: Parasite Immunology - April 24, 2008 Category: Parasitology Tags: article Source Type: journals

Control of Toxoplasma gondii infection by athymic LEW-Whnrnu ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY In immunocompetent rats and humans infection with Toxoplasma gondii remains mostly without overt clinical symptoms, but can be fatal, if the T-cell response is impaired. For a better understanding of the lack of control of T. gondii infection ...
Source: Parasite Immunology - April 21, 2008 Category: Parasitology Tags: article Source Type: journals

Haemonchus contortus calreticulin binds to C-reactive protein of its host, a novel survival strategy of the parasiteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Calreticulin (CalR), a Ca2+ binding multifunctional protein, is secreted by the parasitic nematode Haemonchus contortus. We have earlier observed binding of this protein to a 24-kDa polypeptide (p24) present in an enriched preparation of ...
Source: Parasite Immunology - April 16, 2008 Category: Parasitology Tags: article Source Type: journals

Effect of GPI anchor moiety on the immunogenicity of DNA plasmids encoding the 19-kDa C-terminal portion of Plasmodium falciparum MSP-1Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The glycosylphosphatidylinositol (GPI)-anchored Plasmodium falciparum merozoite surface protein 1 (MSP-1) is a widely studied malaria vaccine candidate. The C-terminal 19-kDa portion of MSP-1 (MSP-119) is of particular interest because this ...
Source: Parasite Immunology - April 15, 2008 Category: Parasitology Tags: article Source Type: journals

Statistical consideration of the role of potential confounders on the association between immunological responses and diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 5, Page 268-270, May 2008.
Source: Parasite Immunology - April 9, 2008 Category: Parasitology Tags: article Source Type: journals

Exposure confounding causes dominance of antiplasmodial IgG3 subclass antibody responses in uncomplicated malariaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 5, Page 267, May 2008.
Source: Parasite Immunology - April 9, 2008 Category: Parasitology Tags: article Source Type: journals

C3 contributes to the cross-protective immunity induced by Babesia gibsoni phosphoriboprotein P0 against a lethal B. rodhaini infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY We have studied the impact of complement component 3 (C3) deficiency on the progression of lethal Babesia rodhaini infection in immune mice. A B. gibsoni ribosomal phosphoprotein P0 (BgP0) previously reported to be a cross-protective antigen ...
Source: Parasite Immunology - March 31, 2008 Category: Parasitology Tags: article Source Type: journals

Transgenesis and neuronal ablation in parasitic nematodes: revolutionary new tools to dissect host–parasite interactionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 4, Page 203-214, April 2008. SUMMARY Ease of experimental gene transfer into viral and prokaryotic pathogens has made transgenesis a powerful tool for investigating the interactions of these pathogens with the host immune system. Recent advances have made this approach feasible for ...
Source: Parasite Immunology - March 6, 2008 Category: Parasitology Tags: article Source Type: journals

Genetically modified parasites and the immune responseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 4, Page 191-193, April 2008.
Source: Parasite Immunology - March 6, 2008 Category: Parasitology Tags: article Source Type: journals

Protective effect of a multiantigenic DNA vaccine against Toxoplasma gondii with co-delivery of IL-12 in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we constructed a multiantigenic DNA vaccine, pSAG1-ROP2-SAG2 and examined its effect with co-delivery of a plasmid encoding IL-12 (pIL-12) as an adjuvant in BALB/c mice against Toxoplasma gondii. After a lethal challenge of T. ...
Source: Parasite Immunology - March 4, 2008 Category: Parasitology Tags: article Source Type: journals

Mucosal antibody responses in experimental hookworm infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Hookworms are bloodfeeding nematodes that reside in the intestinal mucosa. These parasites secrete proteins that induce robust systemic immune responses in humans and experimental animals. By contrast, mucosal immune responses in and around the ...
Source: Parasite Immunology - February 29, 2008 Category: Parasitology Tags: article Source Type: journals

Failure of ES-62 to inhibit T-helper type 1 responses to other filarial nematode antigensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY ES-62 is a secreted protein of filarial nematodes that possesses multiple immunomodulatory activities. A full characterization of these activities awaits elucidation but to date it has been shown that ES-62 can inhibit pro-inflammatory/Th1 immune ...
Source: Parasite Immunology - February 29, 2008 Category: Parasitology Tags: article Source Type: journals

Abnormal IFN-γ-dependent immunoproteasome modulation by Trypanosoma cruzi-infected macrophagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Proteasomes are the main producers of Ag loaded onto MHC class I molecules. Following IFN-γ stimulation however, the constitutive subunits of the proteasome are replaced by the immunosubunits low molecular weight protein 2 (LMP2), multicatalytic ...
Source: Parasite Immunology - February 26, 2008 Category: Parasitology Tags: article Source Type: journals

Transgenic Leishmania and the immune response to infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Genetic manipulation of single-celled organisms such as the Leishmania parasite enables in depth analysis of the consequences of genotypic change on biological function. In probing the immune responses to infection, use of transgenic Leishmania ...
Source: Parasite Immunology - February 4, 2008 Category: Parasitology Tags: article Source Type: journals

Mechanisms of leucocyte recruitment to the inflamed large intestine: redundancy in integrin and addressin usageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 3, Page 163-170, March 2008. SUMMARY The caecal-dwelling nematode Trichuris muris provides a natural model of human whipworm infection. Resistance to T. muris is dependent on a host Th2 response, and CD4+ Th2 cells migrate to the gut-associated lymphoid tissue (GALT) to elicit ...
Source: Parasite Immunology - January 30, 2008 Category: Parasitology Tags: article Source Type: journals

The influence of glutathione modulators on the course of Leishmania major infection in susceptible and resistant miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 3, Page 171-174, March 2008. SUMMARY Glutathione (GSH) has an important dual role in parasite–host relationship in Leishmania major infection. Our previous studies showed that both antioxidant systems, glutathione and trypanothione/trypanothione reductase, participate in the ...
Source: Parasite Immunology - January 30, 2008 Category: Parasitology Tags: article Source Type: journals

Humoral immune response in IL-12 and IFN-γ deficient mice after infection with Cryptosporidium parvumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 3, Page 151-161, March 2008. SUMMARY Infection with Cryptosporidium spp. causes diarrhoeal disease and has become an important medical and veterinary problem especially in the immunocompromised host. The importance of the adaptive immune response, with CD4+ T-lymphocytes being the ...
Source: Parasite Immunology - January 30, 2008 Category: Parasitology Tags: article Source Type: journals

Cytokine gene expression and NF-κB activation following infection of intestinal epithelial cells with Eimeria bovis or Eimeria alabamensis in vitroEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 3, Page 175-179, March 2008. SUMMARY In cattle, Eimeria produces clinical disease with different degrees of severity, depending on the dominant species. Eimeria bovis triggers severe intestinal damage, while E. alabamensis causes minimal damage. Cytokines and other factors derived ...
Source: Parasite Immunology - January 30, 2008 Category: Parasitology Tags: article Source Type: journals

Identification of antigenic proteins from Echinostoma caproni (Trematoda) recognized by mouse immunoglobulins M, A and G using an immunoproteomic approachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Antigenic proteins of Echinostoma caproni (Trematoda) against mouse IgM, IgA, IgG, IgG1 and IgG2a were investigated by immunoproteomics. Excretory/secretory products (ESP) of E. caproni separated by two-dimensional (2D) gel electrophoresis were ...
Source: Parasite Immunology - January 23, 2008 Category: Parasitology Tags: article Source Type: journals

What can transgenic parasites tell us about the development of Plasmodium-specific immune responses?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Malaria infects 500 million people and kills an estimated 2·7 million annually, representing one of the most significant diseases in the world. However, efforts to develop effective vaccines have met with limited success. One reason is our lack ...
Source: Parasite Immunology - January 23, 2008 Category: Parasitology Tags: article Source Type: journals

Genetic manipulation of African trypanosomes as a tool to dissect the immunobiology of infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY The variant surface glycoprotein (VSG) coat of African trypanosomes exhibits immunobiological functions distinct from its prominent role as a variant surface antigen. In order to address questions regarding immune stealth effects of VSG switch-...
Source: Parasite Immunology - January 18, 2008 Category: Parasitology Tags: article Source Type: journals

Advances in the use of genetically engineered parasites to study immunity to Toxoplasma gondiiEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Studying in vivo biology and the host immune response to Toxoplasma gondii has yielded many insights into the pathogenesis of this parasitic organism. It is recognized that this infection in immune competent hosts elicits a strong Th1-type ...
Source: Parasite Immunology - January 8, 2008 Category: Parasitology Tags: article Review Articles Source Type: journals

Emerging technologies and their applications in interactions between nutrition and immunity to gastrointestinal parasites in sheepEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 2, Page 101-111, February 2008. SUMMARY Despite the plethora of evidence on the consequences of host nutrition on their immune responses to gastrointestinal parasites, the identity of molecules and mechanisms that drive the manifestations of immunity under nutrient abundance are not ...
Source: Parasite Immunology - January 7, 2008 Category: Parasitology Tags: article Review Articles Source Type: journals

Trade-offs and benefits: implications of promoting a strong immunity to gastrointestinal parasites in sheepEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 2, Page 123-132, February 2008. SUMMARY The search for sustainable control regimes for gastrointestinal nematode parasites in grazing livestock has resulted in strategies that include assisting sheep to promote a strong immune response. However, the immune response imposes a ...
Source: Parasite Immunology - January 7, 2008 Category: Parasitology Tags: article Review Articles Source Type: journals

Influence of periparturient nutritional demand on resistance to parasites in livestockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 2, Page 113-121, February 2008. SUMMARY Periparturient relaxation of immunity (PPRI) to gastrointestinal nematode parasites may have a nutritional basis, as the increasing nutrient demand at times of nutrient scarcity during late pregnancy and subsequent lactation may result in a ...
Source: Parasite Immunology - January 7, 2008 Category: Parasitology Tags: article Review Articles Source Type: journals

Manipulating host immunity to improve nematode parasite control – Quo vaditEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 30, Issue 2, Page 71-77, February 2008.
Source: Parasite Immunology - January 7, 2008 Category: Parasitology Tags: article Review Articles Source Type: journals

Determination of the relative avidity of the specific IgG antibodies in human toxocariasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parasite Immunology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SUMMARY Human toxocariasis is a zoonosis caused by infection with larvae of the ascarid nematode Toxocara canis and, less frequently, T. cati. Our study developed a method for distinguishing distant from recent human toxocariasis by assessing the avidity ...
Source: Parasite Immunology - January 5, 2008 Category: Parasitology Tags: article Brief Definitive Reports Source Type: journals