Impaired interleukin ‐4 signalling promotes establishment of Haemonchus contortus in sheep
SummaryReduced worm burden in St. Croix (STC) sheep duringHaemonchus contortus (Hc) infection is predicated on rapid interleukin ‐4 (IL‐4) signalling and T helper type 2 immune (Th2) response. The aim of these studies was to further elucidate differences in Th2 responses by STC and Suffolk (SUF) sheep. Ten days after challenge Hc infection, peripheral blood mononuclear cells (PBMC) were collected and cultured with larval (HcLA) and adult worm (HcWA) antigen. STC PBMC produced nearly twice as much IL‐4 as SUF (823.57 pg/mL vs 454.28 pg/mL) at 6 hours of HcLA culture despite no difference inIL ‐4 gene expression a...
Source: Parasite Immunology - November 25, 2018 Category: Parasitology Authors: Jesica R. Jacobs,
Scott P. Greiner,
Scott A. Bowdridge Tags: ORIGINAL ARTICLE Source Type: research
Sambucus ebulus extract stimulates cellular responses in cutaneous leishmaniasis
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - November 25, 2018 Category: Parasitology Authors: Maryam Heidari ‐Kharaji,
Vahid Fallah‐Omrani,
Alireza Badirzadeh,
Behnam Mohammadi‐Ghalehbin,
Mohammad Ali Nilforoushzadeh,
Leila Masoori,
Hossein Montakhab‐Yeganeh,
Mehrak Zare Tags: Original Paper Source Type: research
How does Toxoplasmosis affect the maternal ‐fetal immune interface and pregnancy?
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - November 24, 2018 Category: Parasitology Authors: Margarida Borges,
T ânia Magalhães Silva,
Carina Brito,
Natércia Teixeira,
Craig W. Roberts Tags: Commissioned Review or Article Source Type: research
Population level changes in schistosome specific antibody levels following chemotherapy
ConclusionThe study results are consistent with praziquantel treatment boosting anti ‐worm antibody responses. However, there is considerable heterogeneity in post‐treatment changes in specific antibody levels that is related to host age and pre‐treatment infection intensity.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - November 22, 2018 Category: Parasitology Authors: Mizuho Fukushige,
Francisca Mutapi,
Mark E.J. Woolhouse Tags: Review Source Type: research
High macrophage activities are associated with advanced periductal fibrosis in chronic Opisthorchis viverrini infection
This article is protected by copyright. All rights reserved (Source: Parasite Immunology)
Source: Parasite Immunology - November 18, 2018 Category: Parasitology Authors: Kanin Salao,
Krongkarn Watakulsin,
Eimorn Mairiang,
Sutas Suttiprapa,
Sirikachorn Tangkawattan,
Steven W. Edwards,
Banchob Sripa Tags: Original Paper Source Type: research
Schistosoma haematobium Cercarial Infection Alters Subsequent Systemic Immune Responses to Eggs But Has Minimal Impact on Immune Responses to Egg Injection of the Bladder
Conclusioncercarial exposure altered systemic responses of several cytokines in bladder egg ‐injected mice, but surprisingly, only modified leptin expression in bladder tissue. This suggests that depending on the specific application, cercarial exposure may not be strictly necessary to model local immune responses in the bladder wall egg injection mouse model of urogenital schistosomiasi s.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - November 11, 2018 Category: Parasitology Authors: Loc Le,
Evaristus Mbanefo,
George Khludenev,
Olivia Lamanna,
Nirad Banskota,
Michael H. Hsieh Tags: Original Paper Source Type: research
Hepcidin mediated iron homeostasis as immune regulator in visceral leishmaniasis patients
ConclusionThe iron homeostasis by hepcidin can serves as one of the crucial determinants for regulating immune cell signaling therefore, targeting iron metabolism, specifically hepcidin alone or in combination with agonists can serve to clear infection.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - November 6, 2018 Category: Parasitology Authors: Bhawana Singh,
Siddharth Sankar Singh,
Shyam Sundar Tags: Original Paper Source Type: research
Maternal helminth infections and the shaping of offspring immunity
Parasite Immunology,Volume 0, Issue ja, -Not available-. (Source: Parasite Immunology)
Source: Parasite Immunology - October 29, 2018 Category: Parasitology Authors: Benjamin G. Dewals,
Laura E. Layland,
Clarissa Prazeres da Costa,
William G. Horsnell Source Type: research
Schistosoma mansoni schistosomula antigens induce Th1/Pro ‐inflammatory cytokine responses
Parasite Immunology, EarlyView. (Source: Parasite Immunology)
Source: Parasite Immunology - October 22, 2018 Category: Parasitology Authors: Moses Egesa,
Lawrence Lubyayi,
Edridah M. Tukahebwa,
Bernard S. Bagaya,
Iain W. Chalmers,
Shona Wilson,
Cornelis H. Hokke,
Karl F. Hoffmann,
David W. Dunne,
Maria Yazdanbakhsh,
Lucja A. Labuda,
Stephen Cose Source Type: research
Application of Dirofilaria immitis Immunoreactive Proteins in Serodiagnosis
Parasite Immunology,Volume 0, Issue ja, -Not available-. (Source: Parasite Immunology)
Source: Parasite Immunology - October 18, 2018 Category: Parasitology Authors: Majid Khanmohammadi,
Reza Falak,
Ahmad Reza Meamar,
Elham Razmjou,
Kobra Mokhtarian,
Mehdi Arshadi,
Nasrin Shayanfar,
Lame Akhlaghi Source Type: research
Impaired IL ‐4 signaling promotes establishment of Haemonchus contortus in sheep
Parasite Immunology,Volume 0, Issue ja, -Not available-. (Source: Parasite Immunology)
Source: Parasite Immunology - October 16, 2018 Category: Parasitology Authors: Jesica R. Jacobs,
Scott P. Greiner,
Scott A. Bowdridge Source Type: research
Immunotherapy of alveolar echinococcosis via PD ‐1/PD‐L1 immune checkpoint blockade in mice
Parasite Immunology,Volume 0, Issue ja, -Not available-. (Source: Parasite Immunology)
Source: Parasite Immunology - October 13, 2018 Category: Parasitology Authors: Junhua Wang,
Fadi Jebbawi,
Anne ‐Pauline Bellanger,
Guido Beldi,
Laurence Millon,
Bruno Gottstein Source Type: research
Cover Image
Parasite Immunology,Volume 40, Issue 11, November 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - October 12, 2018 Category: Parasitology Authors: Sarah M. Gunter,
Leroy Versteeg,
Kathryn M. Jones,
Brian P. Keegan,
Ulrich Strych,
Maria Elena Bottazzi,
Peter J. Hotez,
Eric L. Brown Source Type: research
Issue Information
Parasite Immunology,Volume 40, Issue 11, November 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - October 12, 2018 Category: Parasitology Source Type: research
Leishmania infection activates host mTOR for its survival by M2 macrophage polarization
Parasite Immunology,Volume 40, Issue 11, November 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - October 12, 2018 Category: Parasitology Authors: Ajay Kumar,
Sushmita Das,
Abhishek Mandal,
Sudha Verma,
Kumar Abhishek,
Ashish Kumar,
Vinod Kumar,
Ayan Kumar Ghosh,
Pradeep Das Source Type: research
