Pediatric Allergy and ImmunologyThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Egg white specific IgE levels in serum as clinical reactivity predictors in the course of egg allergy follow-upEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Montesinos E, Martorell A, Félix R, Cerdá JC. Egg white specific IgE levels in serum as clinical reactivity predictors in the course of egg allergy follow-up.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S It is thought that the natural evolution of egg allergy has a good tolerance prognosis. However, there are few follow-up studies that determine the exact probability of tolerance. The aim of this study was to determine the likelihood that children younger than 2,5 years of age with allergy to egg would eventually have tolerance to it and to analyze if monitoring egg white[ndash]specific IgE level over time c...
Source: Pediatric Allergy and Immunology - November 20, 2009 Category: Allergy & Immunology Authors: Elena Montesinos, Antonio Martorell, Rubén Félix, Juan Carlos Cerdá Source Type: journals

Children with frequent infections: A proposal for a stepwise assessment and investigation of the immune systemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cassimos DC, Liatsis M, Stogiannidou A, Kanariou MG. Children with frequent infections: A proposal for a stepwise assessment and investigation of the immune system. 'The immune defense to foreign invaders' Symphony. Which instrument is out of tune?Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Although many children develop frequent infections, only a few have an underlying immune disorder. Children with dysfunction of the immune system develop frequent infections and/or recurrent, persistent, severe, and rare infections. The aim of this review is to provide to the clinician a valuable tool for recognizing any ...
Source: Pediatric Allergy and Immunology - November 17, 2009 Category: Allergy & Immunology Authors: Dimitrios C. Cassimos, Manolis Liatsis, Anastasia Stogiannidou, Maria G. Kanariou Source Type: journals

Detection of pulmonary complications in common variable immunodeficiencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Touw CML, van de Ven AA, de Jong PA, Terheggen-Lagro S, Beek E, Sanders EAM, van Montfrans JM. Detection of pulmonary complications in common variable immunodeficiency.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Pulmonary complications are frequently observed in common variable immunodeficiency (CVID). We reviewed the literature related to radiologic imaging techniques and pulmonary function tests (PFT) for diagnosing pulmonary complications in CVID. Scientific publications related to CVID (or primary hypogammaglobulinemia), pulmonary complications, PFT, chest X-ray (CXR), and high-resolution computed tomogr...
Source: Pediatric Allergy and Immunology - November 13, 2009 Category: Allergy & Immunology Authors: Catharina M. L. Touw, Annick A. van de Ven, Pim A. de Jong, Suzanne Terheggen-Lagro, Erik Beek, Elisabeth A. M. Sanders, Joris M. van Montfrans Source Type: journals

Wheeze in children: the impact of parental education on atopic and non-atopic symptomsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
de Meer G, Reijneveld SA, Brunekreef B. Wheeze in children: the impact of parental education on atopic and non-atopic symptoms.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S There is conflicting evidence for the relationship between parental socioeconomic position and their children's asthma. The aim of this study was to investigate relationships between parental education and respiratory symptoms in their children, distinguishing atopic and non-atopic symptoms. A cross-sectional survey among 3262 elementary school children (age 8[ndash]13) was performed; data on parental education were obtained for 3213 childr...
Source: Pediatric Allergy and Immunology - November 13, 2009 Category: Allergy & Immunology Authors: Gea de Meer, Sijmen A Reijneveld, Bert Brunekreef Source Type: journals

Lung function at 10 yrs is not improved by early corticosteroid treatment in asthmatic childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lødrup Carlsen KC, Devulapalli CS, Mowinckel P, Håland G, Munthe-Kaas MC, Carlsen K-H. Lung function at 10 yrs is not improved by early corticosteroid treatment in asthmatic children.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Early intervention with inhaled corticosteroid (ICS) treatment for lung function development in childhood is debated. In view of lung function at birth, we aimed to assess if early use of ICS influenced lung function at 10 yrs of age. A 10-yr follow-up study of 614/802 children (mean age 10.9 ± 0.9 yrs) with lung function measurements at birth in the Environment and Childhood Asthma...
Source: Pediatric Allergy and Immunology - November 13, 2009 Category: Allergy & Immunology Authors: Karin C. Lødrup Carlsen, Chandra Sekhar Devulapalli, Petter Mowinckel, Geir Håland, Monica Cheng Munthe-Kaas, Kai-Håkon Carlsen Source Type: journals

Changes in faecal microbiota of infants with cow's milk protein allergy – a Spanish prospective case–control 6-month follow-up studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thompson-Chagoyan OC, Vieites JM, Maldonado J, Edwards C, Gil A. Changes in faecal microbiota of infants with cow's milk protein allergy [ndash] a Spanish prospective case[ndash]control 6-month follow-up study.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Major differences have been found in gut microbiota between healthy and allergic children, and a possible association between allergy and altered microbiota patterns have been postulated. The main object of the study was to compare the faecal microbiota between healthy and cow's milk protein allergy (CMPA) infants at the baseline immediately after the diagnos...
Source: Pediatric Allergy and Immunology - November 2, 2009 Category: Allergy & Immunology Authors: Oscar C. Thompson-Chagoyan, Jose M. Vieites, Jose Maldonado, Christine Edwards, Angel Gil Source Type: journals

DNA damage and glutathione level in children with asthma bronchiale: Effect of antiasthmatic therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, oxidative DNA damage (strand breaks and Fpg-sensitive sites) is at a high level in children with asthma. DNA damage parameters and GSH level were found to be decreased after therapy. Our findings imply that antiasthmatic therapy including glucocorticosteroids not only controls asthma but also decreases mutation risk in children with asthma bronchiale. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - October 14, 2009 Category: Allergy & Immunology Authors: Canan Hasbal, Bagdagul Y. Aksu, Solen Himmetoglu, Yildiz Dincer, Eylem E. Koc, Sami Hatipoglu, Tulay Akcay Source Type: journals

Treatment of severe vernal keratoconjunctivitis with 1% topical cyclosporine in an Italian cohort of 197 childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tesse R, Spadavecchia L, Fanelli P, Rizzo G, Procoli U, Brunetti L, Cardinale F, Miniello VL, Bellizzi M, Armenio L. Treatment of severe vernal keratoconjunctivitis with 1% topical cyclosporine in an Italian cohort of 197 children.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The purpose of our study was to verify the efficacy of prolonged cycles of 1% topical cyclosporine in improving severe form of vernal keratoconjunctivitis (VKC) in childhood and investigate for factors affecting the response to therapy. We conducted an open trial involving 197 children with severe VKC, who received topical cyclosporine 1%...
Source: Pediatric Allergy and Immunology - October 14, 2009 Category: Allergy & Immunology Authors: Riccardina Tesse, Laura Spadavecchia, Pietro Fanelli, Giovanna Rizzo, Ugo Procoli, Luigia Brunetti, Fabio Cardinale, Vito L. Miniello, Mario Bellizzi, Lucio Armenio Source Type: journals

Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM, Ji GE. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Controversy exists regarding the preventive effect of probiotics on the development of eczema or atopic dermatitis. We investigated whether supplementation of probiotics prevents the development of eczema in infants at high risk. In a randomized, double-blind, placebo-controlled trial, 112 pregnant women w...
Source: Pediatric Allergy and Immunology - October 14, 2009 Category: Allergy & Immunology Authors: Ji Yeun Kim, Jung Hyun Kwon, So Hyun Ahn, Sang Il Lee, Young Shin Han, Young Ok Choi, Soo Young Lee, Kang Mo Ahn, Geun Eog Ji Source Type: journals

Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohortEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sucharew H, Ryan PH, Bernstein D, Succop P, Khurana Hershey GK, Lockey J, Villareal M, Reponen T, Grinshpun S, LeMasters G. Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Though studies have investigated the association between air pollution and respiratory health outcomes in children, few have focused on night cough. The study objective was to simultaneously evaluate family factors (i.e., race, gender, maternal and paternal asthma, and breastfeeding), health (allergen sensitization and wheezing symptoms), home factors (...
Source: Pediatric Allergy and Immunology - October 11, 2009 Category: Allergy & Immunology Authors: Heidi Sucharew, Patrick H. Ryan, David Bernstein, Paul Succop, Gurjit K. Khurana Hershey, James Lockey, Manuel Villareal, Tiina Reponen, Sergey Grinshpun, Grace LeMasters Source Type: journals

The prognosis of wheat hypersensitivity in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, almost all children with wheat hypersensitivity can tolerate wheat by adolescence. Sensitization to gliadin is associated with a slower achievement of tolerance and an increased risk of asthma. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - September 29, 2009 Category: Allergy & Immunology Authors: Anne Kotaniemi-Syrjänen, Kati Palosuo, Tuomas Jartti, Mikael Kuitunen, Anna S. Pelkonen, Mika J. Mäkelä Source Type: journals

Eosinophil activity in infants hospitalized for wheezing and risk of persistent childhood asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hyvärinen MK, Kotaniemi-Syrjänen A, Reijonen TM, Piippo-Savolainen E, Korppi M. Eosinophil activity in infants hospitalized for wheezing and risk of persistent childhood asthma.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Eosinophilic inflammation has a central role in the pathogenesis of asthma. We aimed to elucidate whether elevated blood eosinophil count (B-EOS), eosinophil cationic protein in serum (S-ECP) or in nasopharyngeal aspirate (NPA-ECP) predict later asthma after hospitalization for wheezing in infancy. In 1992[ndash]1993, 100 infants aged (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - September 29, 2009 Category: Allergy & Immunology Authors: Mari K. Hyvärinen, Anne Kotaniemi-Syrjänen, Tiina M. Reijonen, Eija Piippo-Savolainen, Matti Korppi Source Type: journals

Residential proximity to main roads during pregnancy and the risk of allergic disorders in Japanese infants: The Osaka Maternal and Child Health StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Miyake Y, Tanaka K, Fujiwara H, Mitani Y, Ikemi H, Sasaki S, Ohya Y, Hirota Y. Residential proximity to main roads during pregnancy and the risk of allergic disorders in Japanese infants: The Osaka Maternal and Child Health Study. Pediatr Allergy Immunol 2009. © 2009 John Wiley & Sons A/S The role of traffic-related air pollution in the initiation of allergic disorders in children is still not clearly understood. The present prospective study examined the relation between proximity of the home during pregnancy to the nearest main road, which was used as a surrogate for traffic-related air pollutants, and the risk of aller...
Source: Pediatric Allergy and Immunology - September 26, 2009 Category: Allergy & Immunology Authors: Yoshihiro Miyake, Keiko Tanaka, Hiroshi Fujiwara, Yasuhiro Mitani, Hiroaki Ikemi, Satoshi Sasaki, Yukihiro Ohya, Yoshio Hirota Source Type: journals

Non-invasive markers of airway inflammation and remodeling in childhood asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows that the presence of bronchial inflammation is detectable in the airways of some IA, as well as in the airways of MA, despite the regular ICS treatment. This study also proposes the need to perform large prospective studies to confirm the importance of measuring specific biomarkers in induced sputum, concomitantly to FeNO analyses, to assess sub-clinical airway inflammation and disease control in children with asthma. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - September 24, 2009 Category: Allergy & Immunology Authors: Rosalia Gagliardo, Stefania La Grutta, Pascal Chanez, Mirella Profita, Alessandra Paternò, Fabio Cibella, Jean Bousquet, Giovanni Viegi, Mark Gjomarkaj Source Type: journals

Development of atopic dermatitis in the DARC birth cohortEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eller E, Kjaer HF, Høst A, Andersen KE, Bindslev-Jensen C. Development of Atopic Dermatitis in the DARC birth cohort.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The aim was to describe the relapsing pattern, sensitization and prognosis of atopic dermatitis (AD) in the first 6 yr in a population-based, prospective birth cohort. The DARC cohort includes 562 children with clinical examinations, specific-IgE and skin prick test at all follow-ups. All children were examined for the development of AD using Hanifin-Rajka criteria and for food hypersensitivity by oral challenges. Severity of AD was measured by obje...
Source: Pediatric Allergy and Immunology - September 23, 2009 Category: Allergy & Immunology Authors: Esben Eller, Henrik Fomsgaard Kjaer, Arne Høst, Klaus Ejner Andersen, Carsten Bindslev-Jensen Source Type: journals

Prevalence of rhinitis-related symptoms in Latin American children – Results of the International Study of Asthma and Allergies in Childhood (ISAAC) phase threeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Solé D, Mallol J, Camelo-Nunes IC, Wandalsen GF, Latin American ISAAC Study Group. Prevalence of rhinitis-related symptoms in Latin American children [ndash] Results of the International Study of Asthma and Allergies in Childhood (ISAAC) phase three.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The aim of this study was to evaluate the prevalence of rhinitis-related symptoms among children living in different parts of Latin America (LA) considering all centers involved in ISAAC Phase Three (Ph3). 93,851 children (6[ndash]7 yr-old) from 35 centers in 14 LA countries and 165,917 adolescents (13[ndash]14 yr-old)...
Source: Pediatric Allergy and Immunology - September 23, 2009 Category: Allergy & Immunology Authors: Dirceu Solé, Javier Mallol, Inês C Camelo-Nunes, Gustavo F Wandalsen Source Type: journals

CD14 polymorphisms in mother and infant, soluble CD14 in breast milk and atopy development in the infant (KOALA Study)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Snijders BEP, Stelma FF, Reijmerink NE, Thijs C, van der Steege G, Damoiseaux JGMC, van den Brandt PA, van Ree R, Postma DS, Koppelman GH. CD14 polymorphisms in mother and infant, soluble CD14 in breast milk and atopy development in the infant (KOALA Study).Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Different CD14 polymorphisms have been associated with atopic phenotypes in infants. In addition, CD14 genotypes of breastfeeding mothers have been associated with soluble CD14 (sCD14) levels in breast milk. The role of CD14 genotypes of infant and mother and their interaction with sCD14 levels in breast milk in...
Source: Pediatric Allergy and Immunology - September 14, 2009 Category: Allergy & Immunology Authors: Bianca E. P. Snijders, Foekje F. Stelma, Naomi E. Reijmerink, Carel Thijs, Gerrit van der Steege, Jan G. M. C. Damoiseaux, Piet A. van den Brandt, Ronald van Ree, Dirkje S. Postma, Gerard H. Koppelman Source Type: journals

Association of nutrient intake and wheeze or asthma in a Greek pre-school populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Emmanouil E, Manios Y, Grammatikaki E, Kondaki K, Oikonomou E, Papadopoulos N, Vassilopoulou E. Association of nutrient intake and wheeze or asthma in a Greek pre-school population.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The rise of asthma prevalence in children observed the last years might be related to several dietary factors/components as suggested by several researchers. We aimed to evaluate the potential relationship between certain nutrients intake and asthma occurrence in a population of pre-school children. In the framework of the cross-sectional study 'Growth, Exercise and Nutrition Epidemiolog...
Source: Pediatric Allergy and Immunology - September 8, 2009 Category: Allergy & Immunology Authors: Evdokia Emmanouil, Yannis Manios, Evangelia Grammatikaki, Katerina Kondaki, Evdokia Oikonomou, Nikolaos Papadopoulos, Emilia Vassilopoulou Source Type: journals

Current management of allergic rhinitis in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Georgalas C, Terreehorst I, Fokkens W. Current management of allergic rhinitis in children.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Over the last 20 years, there has been significant progress in our understanding of the pathophysiology of allergic rhinitis, including the discovery of new inflammatory mediators, the link between asthma and allergic rhinitis ('one airway[ndash]one disease' concept) and the introduction of novel therapeutic modalities. These new insights have been documented in the Allergic Rhinitis and its Impact on Asthma guidelines and have led to the creation of evidence-based management...
Source: Pediatric Allergy and Immunology - September 8, 2009 Category: Allergy & Immunology Authors: Christos Georgalas, Ingrid Terreehorst, Wytske Fokkens Source Type: journals

Diseases mimicking allergic rhinitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present three case histories and discussion of several other diagnoses which should be considered. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - September 8, 2009 Category: Allergy & Immunology Authors: S. B. C. Gane, G. K. Scadding Source Type: journals

Depressive symptoms amongst asthmatic children's caregiversEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Szabó A, Mezei G, Kővári É, Cserháti E. Depressive symptoms amongst asthmatic children's caregivers.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S We wanted to find out, whether the number of depressive symptoms is higher amongst asthmatic children's caregivers, compared to international data, to the Hungarian population average, and to parents of children with chronic renal disease. Are these depressive symptoms connected to the children's psychological status, asthma severity or current asthma symptoms? One-hundred and eight, 7- to 17-yr-old asthmatic children were enrolled, who have been treated a...
Source: Pediatric Allergy and Immunology - September 8, 2009 Category: Allergy & Immunology Authors: Alexandra Szabó, Györgyi Mezei, Éva Kővári, Endre Cserháti Source Type: journals

The association between early sensitization patterns and subsequent allergic disease. The DARC birth cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study describes the natural course of sensitization as measured by skin prick test (SPT) and specific immunoglobulin E (S-IgE) and analyses the association between early sensitization patterns and subsequent allergic disease at 6 yr of age. In an ongoing population-based birth cohort study of 562 children, follow-up visits were performed at 0, 3, 6, 9, 12, 18, 36, and 72 months. Visits included an interview, physical examination, SPTs, and S-IgE measurements for 12 food and inhalant allergens. The frequency of S-IgE sensitization to [ge]1 inhalant allergen was constant from 0 to 6 months (9[ndash]10%), decreased at 12...
Source: Pediatric Allergy and Immunology - September 7, 2009 Category: Allergy & Immunology Authors: Henrik Fomsgaard Kjaer, Esben Eller, Klaus Ejner Andersen, Arne Høst, Carsten Bindslev-Jensen Source Type: journals

Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneouslyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Omalizumab represents an important clinical advance in the management of allergic diseases and can be considered to be safe in children. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - September 2, 2009 Category: Allergy & Immunology Authors: Wolfgang Kamin, Matthias Volkmar Kopp, Frank Erdnuess, Uwe Schauer, Stefan Zielen, Ulrich Wahn Source Type: journals

Serum leptin and adiponectin levels correlate with severity of allergic rhinitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hsueh K-C, Lin Y-J, Lin HC, Lin C-Y. Serum leptin and adiponectin levels correlate with severity of allergic rhinitis.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The aim of this study was to evaluate the roles of leptin and adiponectin, which are adipokines produced by adipose tissue, in childhood allergic rhinitis (AR), and their association with severity of AR, parameters of atopy and pro-/anti-inflammatory cytokines. Serum levels of leptin, adiponectin, mite allergen-specific and total immunoglobulin E, eosinophil cationic protein (ECP), and pro- and anti-inflammatory cytokines were analysed in 97 non-ast...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Kai-Chung Hsueh, Ying-Ju Lin, Hsiao Chuan Lin, Ching-Yuang Lin Source Type: journals

Urinary nitric oxide excretion in infants with eczemaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Devenney I, Norrman G, Forslund T, Fälth-Magnusson K, Sundqvist T. Urinary nitric oxide excretion in infants with eczema.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Eczema is characterized by inflammation of the skin and is commonly associated with food allergy. It has been suggested that nitric oxide (NO) is an important player in eczema, food allergy and intestinal inflammation. The aim of this study was to assess the levels of urinary NO breakdown products in infants with eczema and the effect of eczema treatment on NO levels. Ninety-four infants with eczema, 58 boys and 36 girls, with a mean age of 7.5 ...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Irene Devenney, Gunilla Norrman, Tony Forslund, Karin Fälth-Magnusson, Tommy Sundqvist Source Type: journals

Early exposure to antibiotics and infections and the incidence of atopic eczema: A population-based cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study describes the complex relationship between early exposure to infections, anti-infectious treatment with antibiotics, and incident AE. Using a German population-based administrative health-care and prescription database, we established a cohort of 370 children not diagnosed as having AE during their first year of life. For each individual child we identified all infections and prescriptions of antibiotics within the first year as well as incident AE within the second year of life. Crude analyses suggested that early infections and exposure to antibiotics are risk factors for AE. However, stratified analyses indic...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Jochen Schmitt, Natalie M. Schmitt, Wilhelm Kirch, Michael Meurer Source Type: journals

Probiotics for allergic respiratory diseases – Putting it into perspectiveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Singh M, Das RR. Probiotics for allergic respiratory diseases [ndash] Putting it into perspective.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Respiratory allergies include allergic rhinitis, sinusitis and asthma. Increasing attention on pathogenesis of allergic airway diseases has given rise to "atopic march" hypothesis i.e. clinical features of atopic eczema occur first and precede the development of asthma and allergic rhinitis. The "hygiene hypothesis" proposes that the increase in allergic diseases reflects a decrease in infections during childhood. Clinical trials also suggest that the exposure to micro...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Meenu Singh, Rashmi Ranjan Das Source Type: journals

Aberrant responses to TLR agonists in pediatric IBD patients; the possible association with increased production of Th1/Th17 cytokines in response to candida, a luminal antigenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined responses to TLR agonists in children with inflammatory bowel disease (IBD). Peripheral blood mononuclear cells (PBMC) obtained from children with IBD [Crohn's disease (CD, n = 10), ulcerative colitis (UC, n = 10)], children with non-IgE-mediated food allergy (NFA, n = 20), and controls (n = 15) were tested for their production of proinflammatory and counter-regulatory cytokines with TLR agonists in comparison with their cytokine production against milk protein and candida. IBD patients were all in the inactive state. IBD PBMC produced more IL-6 with all the TLR agonists tested than controls. CD PBMC produced m...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Harumi Jyonouchi, Lee Geng, Agnes Cushing-Ruby, Iona M. Monteiro Source Type: journals

Relationship between infant weight gain and later asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Paul IM, Camera L, Zeiger RS, Guilbert TW, Bacharier LB, Taussig LM, Morgan WJ, Covar RA, Krawiec M, Bloomberg GR, Mauger DT. for the Childhood Asthma Research and Education (CARE) Network. Relationship between infant weight gain and later asthma.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Like obesity, the prevalence of asthma has increased over the past several decades. Accelerated patterns of infant growth have been associated with obesity and its co-morbidities. We aimed to determine if infant weight gain pattern is associated with asthma development later in childhood. Birth weight, growth, pulmonary fu...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: Ian M. Paul, Lindsay Camera, Robert S. Zeiger, Theresa W. Guilbert, Leonard B. Bacharier, Lynn M. Taussig, Wayne J. Morgan, Ronina A. Covar, Marzena Krawiec, Gordon R. Bloomberg, David T. Mauger Source Type: journals

Childhood evaluation of salmeterol tolerance – A double-blind randomized controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Carroll WD, Jones PW, Boit P, Clayton S, Cliff I, Lenney W. Childhood evaluation of salmeterol tolerance [ndash] a double-blind randomized controlled trial.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Long acting [beta]2-agonists (LABA) are widely used in children with asthma. Data from adults suggest that there is tachyphylaxis particularly to the bronchoprotective effects of LABA. There are no data in children. To determine whether LABA are subject to tachyphylaxis in school-aged children. Children were eligible for participation if they remained symptomatic on 400 [mu]g of beclometasone dipropionate equiva...
Source: Pediatric Allergy and Immunology - August 29, 2009 Category: Allergy & Immunology Authors: W. D. Carroll, P. W. Jones, P. Boit, S. Clayton, I. Cliff, W. Lenney Source Type: journals

Serological and clinical characteristics of children with peanut sensitization in an Asian communityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chiang WC, Pons L, Kidon MI, Liew WK, Goh A, Wesley Burks A. Serological and clinical characteristics of children with peanut sensitization in an Asian community.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S In the past two decades, peanut allergy prevalence has increased in the West but has been perceived as having remained low in Asia. To review the clinical presentation of Asian children with peanut hypersensitivity and measure their IgE responses to major peanut allergens. We enrolled 31 children presenting with various allergies and a positive skin prick test to peanut from the Children's hospital outpati...
Source: Pediatric Allergy and Immunology - August 20, 2009 Category: Allergy & Immunology Authors: Wen Chin Chiang, Laurent Pons, Mona Iancovici Kidon, Woei Kang Liew, Anne Goh, A. Wesley Burks Source Type: journals

Teenagers' experiences of living with food hypersensitivity: A qualitative studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed to describe the lived experiences of teenagers with food hypersensitivity. Individual semi-structured interviews were conducted with 21 teenagers (13[ndash]18 yr) with food hypersensitivity to a variety of foods and analysed using a phenomenological approach. Teenagers described living with (or coming to know) food hypersensitivity (FHS) as a way of life but still found living with food hypersensitivity to be burdensome. A necessary part of living with food hypersensitivity was coping with associated burden; a variety of coping strategies were employed to this effect. Teenagers described ways in which the ...
Source: Pediatric Allergy and Immunology - August 20, 2009 Category: Allergy & Immunology Authors: Heather MacKenzie, Graham Roberts, Darren van Laar, Taraneh Dean Source Type: journals

Allergic status of schoolchildren with food allergy to eggs, milk or wheat in infancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Kusunoki T, Morimoto T, Nishikomori R, Heike T, Fujii T, Nakahata T. Allergic status of schoolchildren with food allergy to eggs, milk or wheat in infancy.Pediatr Allergy Immunol 2009.© 2009 The AuthorsJournal compilation © 2009 John Wiley & Sons A/S Although children allergic to eggs, milk or wheat in infancy tend to become tolerant by school age, the allergic status of these children at school age has not been well evaluated. To investigate the allergic status of schoolchildren who avoided eggs, milk or wheat because of an immediate-type allergic reaction at (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - August 20, 2009 Category: Allergy & Immunology Authors: Takashi Kusunoki, Takeshi Morimoto, Ryuta Nishikomori, Toshio Heike, Tatsuya Fujii, Tatsutoshi Nakahata Source Type: journals

Parental anxiety before and after food challenges in children with suspected peanut and hazelnut allergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Zijlstra WT, Flinterman AE, Soeters L, Knulst AC, Sinnema G, L'Hoir MP, Pasmans SG. Parental anxiety before and after food challenges in children with suspected peanut and hazelnut allergy.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S As ingestion of peanut and hazelnut by allergic children is potentially life threatening, parents of these children need to be vigilant about their child's dietary intake. This may cause high levels of anxiety. To assess parental anxiety about food-allergic reaction in their child (state anxiety) and their personal disposition to anxiety (trait anxiety). Parental anxiety was inve...
Source: Pediatric Allergy and Immunology - August 16, 2009 Category: Allergy & Immunology Authors: Wieneke T. Zijlstra, Annebeth E. Flinterman, Lotte Soeters, André C. Knulst, Gerben Sinnema, Monique P. L'Hoir, Suzanne G. Pasmans Source Type: journals

Comparability of a hand-held nitric oxide analyser with online and offline chemiluminescence-based nitric oxide measurementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Schiller B, Hammer J, Barben J, Trachsel D. Comparability of a hand-held nitric oxide analyser with online and offline chemiluminescence-based nitric oxide measurement.Pediatr Allergy Immunol 2009.© 2009 The AuthorsJournal compilation © 2009 Blackwell Munksgaard Practicability is crucial for successful implementation of fractional exhaled nitric oxide (FeNO) measurement into asthma management. The study aimed at comparing a conventional chemiluminescence NO analyser (EcoMedics®) with a hand-held device (NIOX MINO®) and offline FeNO measurement using a commercially available system in an unselected cohort of children ag...
Source: Pediatric Allergy and Immunology - August 12, 2009 Category: Allergy & Immunology Authors: Barbara Schiller, Juerg Hammer, Juerg Barben, Daniel Trachsel Source Type: journals

Induction of IL-10+ CD4+ CD25+ regulatory T cells with decreased NF-κB expression during immunotherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tsai Y-G, Chiou Y-L, Chien J-W, Wu H-P, Lin C-Y. Induction of IL-10+ CD4+ CD25+ regulatory T cells with decreased NF-[kappa]B expression during immunotherapy.Pediatr Allergy Immunol 2009.© 2009 The AuthorsJournal compilation © 2009 Blackwell Munksgaard MyD88 is a major toll-like receptor (TLR) adaptor to activate NF-[kappa]B, which acts as a mater switch for allergic inflammation disease. Sterile hust dust extracts have been reported with TLR-dependent immunostimulatory activities. The aim of this study was to evaluate whether Dermatophagoides pteronyssinus (Der p) immunotherapy may increase IL-10+ CD4+ CD25+ T cells wit...
Source: Pediatric Allergy and Immunology - August 12, 2009 Category: Allergy & Immunology Authors: Yi-Giien Tsai, Ya-Ling Chiou, Jien-Wen Chien, Han-Ping Wu, Ching-Yuang Lin Source Type: journals

Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sørensen M, Allermann L, Vogel U, Andersen PS, Jespersgaard C, Loft S, Raaschou-Nielsen O. Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children.Pediatr Allergy Immunol 2009.© 2009 The AuthorsJournal compilation © 2009 John Wiley & Sons A/S Persistent wheeze in childhood is associated with airway inflammation. The present study investigated relationships between polymorphisms in inflammatory genes, exposure to tobacco smoke and furred pets and risk of recurrent wheeze in children. Within a birth cohort of 101,042 children we identified 1111 eighteen month old cases with recurrent whee...
Source: Pediatric Allergy and Immunology - August 5, 2009 Category: Allergy & Immunology Authors: Mette Sørensen, Leila Allermann, Ulla Vogel, Paal Skytt Andersen, Cathrine Jespersgaard, Steffen Loft, Ole Raaschou-Nielsen Source Type: journals

Allergic rhinitis in the child and associated comorbiditiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sih T, Mion O. Allergic rhinitis in the child and associated comorbidities.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Allergic rhinitis (AR) typically presents after the second year of life, but the exact prevalence in early life is unknown. AR affects 10[ndash]30% of the population, with the greatest frequency found in children and adolescents. It appears that the prevalence has increased in the pediatric population. As the childs' immune system develops between the 1st and 4th yr of life, those with an atopic predisposition begin to express allergic disease with a clear Th2 response to allergen exposure, ...
Source: Pediatric Allergy and Immunology - August 1, 2009 Category: Allergy & Immunology Authors: Tania Sih, Olavo Mion Source Type: journals

The impact of ambient NO on online measurements of exhaled and nasal NO: The PIAMA studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gehring U, Oldenwening M, Brunekreef B, Wieringa MH, Kerkhof M, Smit HA, van der Ent CK, De Jongste JC. The impact of ambient NO on online measurements of exhaled and nasal NO: The PIAMA study.Pediatr Allergy Immunol 2009.© 2009 The AuthorsJournal compilation © 2009 John Wiley & Sons A/S The guidelines of the American Thoracic Society (ATS) and the European Respiratory Society (ERS) for standardized measurements of exhaled nitric oxide (NO) state that for online measurements the inhaled air should be free of NO. As it is not always possible to create an NO-free environment, inhalation through an NO-scrubber is used. To d...
Source: Pediatric Allergy and Immunology - July 16, 2009 Category: Allergy & Immunology Authors: Ulrike Gehring, Marieke Oldenwening, Bert Brunekreef, Marjan H. Wieringa, Marjan Kerkhof, Henriette A. Smit, Cornelis K. van der Ent, Johan C. De Jongste Source Type: journals

Oral desensitization to milk: how to choose the starting dose!Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion the end point skin prick test procedure results safe and easy to be performed in each single child in order to find out the starting dose for oral desensitization to milk, also by taking into account the individual variability. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - July 12, 2009 Category: Allergy & Immunology Authors: Francesca Mori, Neri Pucci, Maria Elisabetta Rossi, Maurizio de Martino, Chiara Azzari, Elio Novembre Source Type: journals

A systematic review of the importance of milk TGF-β on immunological outcomes in the infant and young childEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Oddy WH, Rosales F. A systematic review of the importance of milk TGF-[beta] on immunological outcomes in the infant and young child.Pediatr Allergy Immunol 2009.© 2009 Mead Johnson Nutrition. Journal compilation © 2009 John Wiley & Sons A/S Cytokines in milk like transforming growth factor-beta (TGF-[beta]) have been shown to induce oral tolerance in experimental animal studies. However, human studies are less consistent with these findings. The primary objective of this review was to conduct a systematic review of published studies on the association between TGF-[beta] identified in human milk and immunological outcome...
Source: Pediatric Allergy and Immunology - July 8, 2009 Category: Allergy & Immunology Authors: Wendy H. Oddy, Francisco Rosales Source Type: journals

A probiotic dairy product containing L. gasseri CECT5714 and L. coryniformis CECT5711 induces immunological changes in children suffering from allergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Martínez-Cañavate A, Sierra S, Lara-Villoslada F, Romero J, Maldonado J, Boza J, Xaus J, Olivares M. A probiotic dairy product containing L. gasseri CECT5714 and L. coryniformis CECT5711 induces immunological changes in children suffering from allergy.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The increase in the prevalence of allergic diseases in children has been attributed to an unbalanced immune response probably due to environmental factors. The immunoregulatory properties of probiotic bacteria could balance the disequilibrium in the immune response causing the allergic response. The aim of this stud...
Source: Pediatric Allergy and Immunology - July 7, 2009 Category: Allergy & Immunology Authors: Ana Martínez-Cañavate, Saleta Sierra, Federico Lara-Villoslada, Julio Romero, José Maldonado, Julio Boza, Jordi Xaus, Mónica Olivares Source Type: journals

Contact to cat or dog, allergies and parental educationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Apfelbacher CJ, Ollert M, Ring J, Behrendt H, Krämer U. Contact to cat or dog, allergies and parental education.Pediatr Allergy Immunol 2009. © 2009 John Wiley & Sons A/S Whether or not associations between animal contact and allergy/atopy are homogeneous across social strata has not yet been investigated. The aim of this study was to estimate the association between animal contact (cat, dog) and allergy/atopy in 6-yr-old school beginners, stratified by parental educational level. A total of 30794, 6-yr old children participated in cross-sectional studies between 1991 and 2000 in Germany. Allergic sensitization to common...
Source: Pediatric Allergy and Immunology - July 7, 2009 Category: Allergy & Immunology Authors: Christian Joachim Apfelbacher, Markus Ollert, Johannes Ring, Heidrun Behrendt, Ursula Krämer Source Type: journals

The Prevalence of food hypersensitivity in young adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study estimated the prevalence of FHS to the most common allergenic foods in an unselected population of young adults. We investigated a cohort of 1272 young adults 22 years of age by questionnaire, skin prick test (SPT) and histamin release (HR) followed by oral challenge to the most common allergenic foods. FHS was divided into primary and secondary FHS. Primary FHS was defined as being independent of pollen sensitization, whereas secondary FHS was defined as reactions to pollen related fruits and vegetables in pollen allergic patients. The questionnaire was returned by 77.1%. Primary FHS was reported by 19.6% and s...
Source: Pediatric Allergy and Immunology - July 6, 2009 Category: Allergy & Immunology Authors: M. Osterballe, C. G. Mortz, T. K. Hansen, K. E. Andersen, C. Bindslev-Jensen Source Type: journals

Allergic rhinitis in school-aged children with asthma – still under-diagnosed and under-treated? A retrospective study in a children's hospitalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ruokonen M, Kaila M, Haataja R, Korppi M, Paassilta M. Allergic rhinitis in school-aged children with asthma [ndash] still under-diagnosed and under-treated? A retrospective study in a children's hospital.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Allergic rhinitis (AR) and asthma can be considered as manifestations of the same disease entity. The treatment of AR may improve also asthma symptoms. The aim of the study was to evaluate, how often AR is diagnosed and treated in patients with asthma. A retrospective chart review in the allergy and asthma unit of a secondary paediatric hospital. From 903 eligible...
Source: Pediatric Allergy and Immunology - July 4, 2009 Category: Allergy & Immunology Authors: M. Ruokonen, M. Kaila, R. Haataja, M. Korppi, M. Paassilta Source Type: journals

Antigenic proteins of Lactobacillus acidophilus that are recognised by serum IgG antibodies in children with type 1 diabetes and coeliac diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Prangli A-L, Utt M, Talja I, Sepp E, Mikelsaar M, Rajasalu T, Uibo O, Tillmann V, Uibo R. Antigenic proteins of Lactobacillus acidophilus that are recognized by serum IgG antibodies in children with type 1 diabetes and coeliac disease.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Immune responses to lactobacilli have been so far insufficiently investigated in patients with autoimmune diseases. We used whole-cell lysate of an indigenous Lactobacillus acidophilus strain isolated from an Estonian child to study serum IgG antibodies in children groups with type 1 diabetes [insulin dependent diabetes mellitus (IDDM...
Source: Pediatric Allergy and Immunology - July 1, 2009 Category: Allergy & Immunology Authors: Anna-Liisa Prangli, Meeme Utt, Ija Talja, Epp Sepp, Marika Mikelsaar, Tarvo Rajasalu, Oivi Uibo, Vallo Tillmann, Raivo Uibo Source Type: journals

Probiotics and prebiotics in atopic dermatitis: review of the theoretical background and clinical evidenceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, at this moment there is not enough evidence to support the use of pro-, pre- or synbiotics for prevention or treatment of AD in children in clinical practice. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - July 1, 2009 Category: Allergy & Immunology Authors: Leontien B. van der Aa, Hugo S.A. Heymans, Wim M.C. van Aalderen, Aline B. Sprikkelman Source Type: journals

Specific oral tolerance induction (SOTI) in pediatric age: Clinical research or just routine practice?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Miceli Sopo S, Onesimo R, Giorgio V, Fundarò C. Specific oral tolerance induction (SOTI) in pediatric age: Clinical research or just routine practice?Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Specific Oral Tolerance (SOTI) is a promising therapy of food allergy, specially for IgE-mediated cow milk allergy (CMA) in pediatric age. Randomized controlled trials have reported that about 35% of children, at least 5 years of age, became full tolerant to cow milk proteins after SOTI. Regard to the safety, literature describes about 200 children who underwent SOTI, with no fatal events. Nevertheless, a considerabl...
Source: Pediatric Allergy and Immunology - July 1, 2009 Category: Allergy & Immunology Authors: Stefano Miceli Sopo, Roberta Onesimo, Valentina Giorgio, Carlo Fundarò Source Type: journals

Effects of pet exposure in the first year of life on respiratory and allergic symptoms in 7-yr-old children. The SIDRIA-2 studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lombardi E, Simoni M, La Grutta S, Viegi G, Bisanti L, Chellini E, Dell'Orco V, Migliore E, Petronio MG, Pistelli R, Rusconi F, Sestini P, Forastiere F, Galassi C and the SIDRIA-2 Collaborative Group. Effects of pet exposure in the first year of life on respiratory and allergic symptoms in 7-yr-old children. The SIDRIA-2 study.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S The effects of pet exposure on the development of respiratory symptoms have recently been the matter of vivid discussion. Our objective was to determine the effects of exposure to cat or dog in the first year of life on subsequent respiratory...
Source: Pediatric Allergy and Immunology - July 1, 2009 Category: Allergy & Immunology Authors: Enrico Lombardi, Marzia Simoni, Stefania La Grutta, Giovanni Viegi, Luigi Bisanti, Elisabetta Chellini, Valerio Dell'Orco, Enrica Migliore, Maria Grazia Petronio, Riccardo Pistelli, Franca Rusconi, Piersante Sestini, Francesco Forastiere, Claudia Galassi Source Type: journals

Early exposure to solid foods and the development of eczema in children up to 4 years of ageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sariachvili M, Droste J, Dom S, Wieringa M, Hagendorens M, Stevens W, van Sprundel M, Desager K, Weyler J. Early exposure to solid foods and the development of eczema in children up to 4 years of age.Pediatr Allergy Immunol 2009.© 2009 John Wiley & Sons A/S Early exposure to solid foods in infancy has been associated with the development of allergic diseases. However, scientific evidence for this is conflicting. The aim of this study was to examine the association between early exposure to solid foods in the infant's diet and the development of eczema up to 4 years of age. We conducted an etiologic case[ndash]control stud...
Source: Pediatric Allergy and Immunology - June 30, 2009 Category: Allergy & Immunology Authors: Manana Sariachvili, Jos Droste, Sandra Dom, Marjan Wieringa, Margo Hagendorens, Wim Stevens, Marc van Sprundel, Kristien Desager, Joost Weyler Source Type: journals