Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study
ConclusionUse of KD is safe and feasible, but the effect on survival has to be proven in a larger cohort of children who start the KD earlier after diagnosis, preferably as adjuvant therapy to fractionated radiotherapy. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 28, 2018 Category: Cancer & Oncology Authors: Elles J.T.M. der Louw,
Roel E. Reddingius,
Joanne F. Olieman,
Rinze F. Neuteboom,
Coriene E. Catsman ‐Berrevoets Tags: RESEARCH ARTICLE Source Type: research
Erratum
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 27, 2018 Category: Cancer & Oncology Tags: ERRATUM Source Type: research
Patients with “ALPS‐like phenotype” diagnosed with immune dysregulation due to LRBA deficiency
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Karen S. Fern ández,
Reuben Antony,
Ashish Kumar Tags: LETTER TO THE EDITOR Source Type: research
Outcomes of observation without empiric intravenous antibiotics in febrile, nonneutropenic pediatric oncology patients
AbstractThere are no consensus guidelines for management of pediatric oncology patients presenting with fever and nonneutropenia, with limited research into the outcomes of withholding empiric i.v. antibiotics. We conducted a prospective cohort study assessing the safety and efficacy of observing well ‐appearing patients presenting with fever and nonneutropenia (absolute neutrophil count ≥ 500 cells/mm3). Of 238 episodes, 82.7% patients were observed with no infectious complications and low overall incidence of bacteremia (3.4%). There were no significant differences in individual clinical variables. We propose that ob...
Source: Pediatric Blood and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Natalie Wu,
William Muller,
Elaine Morgan Tags: BRIEF REPORT Source Type: research
The challenge of defining “ultra‐high‐risk” neuroblastoma
AbstractGiven the biological and clinical heterogeneity of neuroblastoma, risk stratification is vital to determining appropriate treatment. Historically, most patients with high ‐risk neuroblastoma (HR‐NBL) have been treated uniformly without further stratification. Attempts have been made to identify factors that can be used to risk stratify these patients and to characterize an “ultra‐high‐risk” (UHR) subpopulation with particularly poor outcome. However, amon g published data, there is a lack of consensus in the definition of the UHR population and heterogeneity in the endpoints and statistical methods used...
Source: Pediatric Blood and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Daniel A. Morgenstern,
Rochelle Bagatell,
Susan L. Cohn,
Michael D. Hogarty,
John M. Maris,
Lucas Moreno,
Julie R. Park,
Andrew D. Pearson,
Gudrun Schleiermacher,
Dominique Valteau ‐Couanet,
Wendy B. London,
Meredith S. Irwin Tags: REVIEW Source Type: research
Pediatric cancer care can be complicated by language barriers: A case involving parents with limited Japanese proficiency
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Kumiko Chino,
Yuya Sasaki,
Naoyuki Miyagawa,
Bryn Meredith,
Kara ‐Marie Delaney,
Hiroaki Goto,
Frances Rosario Tags: LETTER TO THE EDITOR Source Type: research
Novel mutation of the TINF2 gene resulting in severe phenotypic Revesz syndrome
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Anusak Sakwit,
Duangnate Rojanaporn,
Pimsiri Mekjaruskul,
Wiboon Suriyajakryuththana,
Werasak Sasanakul,
Nongnuch Sirachainan Tags: LETTER TO THE EDITOR Source Type: research
Understanding care and outcomes in adolescents and young adults with cancer: A review of the AYA HOPE study
AbstractHistorically, adolescents and young adults (AYA) diagnosed with cancer have been an understudied population, and their unique care experiences, needs, and outcomes were not well understood. Thus, 10 years ago, the National Cancer Institute supported the fielding of the Adolescent and Young Adult Health Outcomes and Patient Experiences (AYA HOPE) study to address this gap. We recruited individuals diagnosed at ages 15 to 39 with germ cell, Hodgkin and non ‐Hodgkin lymphoma, acute lymphoblastic leukemia, and sarcoma from Surveillance, Epidemiology, and End Results cancer registries into the first multicenter popula...
Source: Pediatric Blood and Cancer - November 21, 2018 Category: Cancer & Oncology Authors: Ashley Wilder Smith,
Theresa Keegan,
Ann Hamilton,
Charles Lynch,
Xiao ‐Cheng Wu,
Stephen M. Schwartz,
Ikuko Kato,
Rosemary Cress,
Linda Harlan,
AYA HOPE Study Collaborative Group Tags: AYA ONCOLOGY: REVIEW Source Type: research
ASPHO Review Course (see http://aspho.org/meetings/2019-review-course/overview)
Pediatric Blood&Cancer, Volume 66, Issue 1, January 2019. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 21, 2018 Category: Cancer & Oncology Tags: ASPHO REVIEW COURSE Source Type: research
Issue Information
Pediatric Blood&Cancer, Volume 66, Issue 1, January 2019. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 21, 2018 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research
Erratum
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 17, 2018 Category: Cancer & Oncology Tags: ERRATUM Source Type: research
Hydroxyurea for Primary Stroke Prevention: The time draweth nigh
Pediatric Blood&Cancer, EarlyView. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 14, 2018 Category: Cancer & Oncology Authors: Marvin E Reid Tags: COMMENTARY Source Type: research
Using the Patient ‐Reported Outcomes Measurement Information System (PROMIS) to measure symptom burden reported by patients with brain tumors
ConclusionsSignificant associations were found between PROMIS and SDS as well as clinical and demographic characteristics. Brief ‐yet‐precise PROMIS CATs can be used to systematically assess symptom burden experienced by children with brain tumors. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 14, 2018 Category: Cancer & Oncology Authors: Jin ‐Shei Lai,
Mary Jo Kupst,
Jennifer L. Beaumont,
Peter E. Manley,
John Han‐Chih Chang,
William F. Hartsell,
Young Kwok,
Allison Piazza Fisher,
Stewart Goldman Tags: RESEARCH ARTICLE Source Type: research
Social adjustment of adolescent cancer patients transitioning off active treatment: A short ‐term prospective mixed methods study
ConclusionsMost adolescent cancer patients are socially well adjusted as they transition off treatment, although a subset have elevated concerns. Interviews provide insight into complex social experiences not captured on questionnaires. Patients may benefit from screening and support during this unique time. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - November 14, 2018 Category: Cancer & Oncology Authors: Sherilynn F. Chan,
Jennifer A. Hoag,
Jeffrey S. Karst,
Kristin M. Bingen Tags: RESEARCH ARTICLE Source Type: research
