Pediatric DermatologyThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Allopurinol-Induced DRESS Syndrome in an Adolescent PatientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A 16-year-old male patient, with a history of essential hypertension enrolled in an experimental drug protocol using allopurinol, presented to our emergency department with a 10-day history of fever. Initial laboratory evaluation revealed leukocytosis, eosinophilia, and transaminitis. After extensive work-up and exclusion of infectious and oncologic etiologies, the diagnosis of allopurinol-induced drug reaction and eosinophilia with systemic symptoms syndrome was carried out. The patient responded to administration of IV methylprednisolone, with complete resolution of symptoms and improvement of laboratory abnorm...
Source: Pediatric Dermatology - October 4, 2009 Category: Dermatology Authors: Ashvin K. Dewan, Ricardo A. Quinonez Source Type: journals

Infant Skin Microstructure Assessed In Vivo Differs from Adult Skin in Organization and at the Cellular LevelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Functional differences between infant and adult skin may be attributed to putative differences in skin microstructure. The purpose of this study was to examine infant skin microstructure in vivo and to compare it with that of adult skin. The lower thigh area of 20 healthy mothers (ages 25[ndash]43) and their biological children (ages 3[ndash]24 months) was examined using in vivo noninvasive methods including fluorescence spectroscopy, video microscopy, and confocal laser scanning microscopy. Stratum corneum and supra-papillary epidermal thickness as well as cell size in the granular layer were assessed from the c...
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Georgios N. Stamatas, Janeta Nikolovski, Michael A. Luedtke, Nikiforos Kollias, Benjamin C. Wiegand Source Type: journals

Comparative Study on the Efficacy, Safety, and Acceptability of Imiquimod 5% Cream versus Cryotherapy for Molluscum Contagiosum in ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: To compare the efficacy, safety and acceptability of imiquimod (IMQ) 5% cream with cryotherapy for the treatment of molluscum contagiosum (MC) in children. Prospective, randomized, comparative, observer blinded study. A total of 74 children, with MC were divided randomly to receive treatment with either IMQ 5% cream (group A) 5 days a week or cryotherapy (group B) once a week until clinical cure or up to a maximum of 16 weeks. All the patients were followed up weekly during active treatment. The patients were followed-up for 6 months after clinical cure to look for recurrence. In the IMQ group (group A), the over...
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Nawaf Al-Mutairi, Azari Al-Doukhi, Shahat Al-Farag, Ahmad Al-Haddad Source Type: journals

Childhood Vitiligo: A Long-term Study of Localized Vitiligo Treated by Noncultured Cellular GraftingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Segmental type was the second most commonly reported in childhood vitiligo. No significant difference has been reported in the prevalence of childhood and adult focal vitiligo. However, the prevalence of segmental vitiligo has been found to be higher in children compared with that in adults. All available medical and phototherapy options are limited by adverse effects or unsatisfactory efficacy. Surgical techniques may be preferred but are not recommended for children as they are time consuming and associated with technical difficulties. In a retrospective review, 25 children aged 4 to 16 years were treated by au...
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Sanjeev V. Mulekar, Abdullah Al Eisa, Mohamed Bilal Delvi, Ahmed Al Issa, Abdul Hamid Al Saeed Source Type: journals

Steroid-induced Periorificial Dermatitis in Children—Clinical Features and Response to Azelaic AcidEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study elaborates the clinical features of periorificial dermatitis in children as well as possible pathogenetic factors and the response to 20% azelaic acid cream. A total of 10 children aged 3 to 12 (mean 7.7) years suffering from nongranulomatous periorificial dermatitis for 3 to 7 (mean 4.9) months were evaluated, and dermatologic examination was carried out. Pretreatment was documented. Skin prick tests with a panel of six common inhalative allergens and patch tests with the European Standard Series were performed. An association between atopy and periorificial dermatitis was evaluated, and patients were screened ...
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Thomas Jansen, Bodo C. Melnik, Dirk Schadendorf Source Type: journals

Eccrine Squamous Metaplasia and Periadnexal Granulomas: New Cutaneous Histopathologic Findings in Cardiofaciocutaneous SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 4-year-old boy who has cardiofaciocutaneous syndrome with previously unreported histopathologic findings of eccrine squamous metaplasia and periadnexal granuloma. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - October 3, 2009 Category: Dermatology Authors: Michelle L. Jeffries, Kyrieckos A. Aleck, Richard A. Bernert, Ronald C. Hansen Source Type: journals

A Case of Ankyloblepharon, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Ectrodactyly: Are the p63 Syndromes Distinct After All?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of an infant with ankyloblepharon, cleft palate, scalp dermatitis, and ectrodactyly. She is unique for having a novel p63 mutation that has not been previously reported. Her case also points to the significant overlap between the p63-associated ectodermal dysplasias and challenges the traditional diagnostic schema for these rare syndromes. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - September 30, 2009 Category: Dermatology Authors: Yvonne E. Chiu, Beth A. Drolet, Kelly J. Duffy, Kristen E. Holland Source Type: journals

Acute Hemorrhagic Edema of Infancy: A Case ReportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Acute hemorrhagic edema of infancy is a rare vasculitic syndrome affecting young children. Although presentation is dramatic and striking, it is a benign disorder. A 9-month-old boy with fever, rinorrhea, edema, and purpuric lesions involving the face, oral mucosa, ears, and extremities was presented. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - July 20, 2009 Category: Dermatology Authors: OYA HALICIOGLU, SEZIN ASIK AKMAN, SEMRA SEN, SUMER SUTCUOGLU, UMIT BAYOL, HAYRUNNISA KARCI Source Type: journals

Halo Congenital Nevocellular Nevi Associated with Extralesional Vitiligo: A Case Series with Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we present nine cases of patients with congenital nevi and vitiligo who uniquely developed both halo formation around the nevi in addition to vitiligo formation in distinctly separate locations. While the precise etiology of halo formation and vitiligo remains uncertain, several theories suggest that both phenomena result from an immunologic response to pigment cells, whether in the "normal" skin of vitiligo or in the excessively pigmented congenital nevus. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - July 19, 2009 Category: Dermatology Authors: Sarah C. Stierman, Emily P. Tierney, Tor A. Shwayder Source Type: journals

Management of Nevus Sebaceous and the Risk of Basal Cell Carcinoma: An 18-Year ReviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Nevus sebaceous (NS) is a common congenital hamartoma of the skin, usually found on the head and neck. It may undergo malignant transformation to basal cell carcinoma (BCC). However the incidence and lifetime risk of malignant transformation is unknown. We performed an 18-year review of all NS excisions at our institution, to report the number of cases of BCC and other neoplasms within excised NS. The aim is to inform physicians who must weigh the risks in recommending excision of a NS in a pediatric patient population with the risk of malignancy. After a database query for years 1990[ndash]2008, charts were revi...
Source: Pediatric Dermatology - July 19, 2009 Category: Dermatology Authors: Heather Rosen, Birgitta Schmidt, Herman P. Lam, John G. Meara, Brian I. Labow Source Type: journals

Assessment of Elementary School Students' Sun Protection BehaviorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Sun exposure at school poses a significant risk to student health and more needs to be carried out to promote the use of a wide-brimmed hat and limiting student sun exposure. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - July 19, 2009 Category: Dermatology Authors: Seft Hunter, Kristen J. Wells, Paul B. Jacobsen, Ji-Hyun Lee, David Boulware, Kymia Love-Jackson, Rania Abdulla, Richard G. Roetzheim Source Type: journals

Extensive Neonatal DermatophytosesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 25-day-old boy who was referred to our dermatology unit for evaluation of extensive annular erythematous lesions on his body. We initially considered the differential diagnoses of candidiasis and neonatal lupus erythematosus but investigations revealed the case as tinea corporis due to a relatively uncommon causative agent, Microsporum gypseum. To the best of our knowledge it is the first case of extensive neonatal dermatophytoses caused by this organism. The possible causes and the role of steroids in producing the clinical picture in our patient are discussed. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - July 19, 2009 Category: Dermatology Authors: Amol Metkar, Anuja Joshi, Vishwanath Vishalakshi, Autar K. Miskeen, Raghunandan Govind Torsekar Source Type: journals

Disseminated Varicella Zoster Virus in an Immunized Child as the Acquired Immunodeficiency Syndrome-defining IllnessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a 10-year-old boy previously immunized to Varicella who presented with herpes zoster with hematogenous dissemination as the Acquired Immunodeficiency Syndrome-defining illness. Disseminated VZV is more commonly seen in human immunodeficiency virus (HIV)-infected individuals with more advanced disease, as was the case with our patient. Disseminated VZV infection in a previously immunized child should raise suspicion for underlying immunosuppression. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - July 19, 2009 Category: Dermatology Authors: Katherine Chilek, Shannon Routhouska, Joan Tamburro Source Type: journals

Quantitative Assessment of Combination Bathing and Moisturizing Regimens on Skin Hydration in Atopic DermatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study quantified cutaneous hydration status after various combination bathing and moisturizing regimens. Four bathing/moisturizer regimens were evaluated in 10 subjects, five pediatric subjects with atopic dermatitis and five subjects with healthy skin. The regimens consisted of bathing alone without emollient application, bathing and immediate emollient application, bathing and delayed application, and emollient application alone. Each regimen was evaluated in all subjects, utilizing a crossover design. Skin hydration was assessed with standard capacitance measurements. In atopic dermatitis subjects, emollient alone ...
Source: Pediatric Dermatology - May 7, 2009 Category: Dermatology Authors: Charles Chiang, Lawrence F. Eichenfield Source Type: journals

Speckled Lentiginous Nevus Syndrome Associated with Musculoskeletal AbnormalitiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 9-year-old boy with a large speckled lentiginous nevus on his trunk, bilateral upper extremities, and neck associated with hyperhidrosis and nonspecific pain in the distribution of the nevus in addition to prominent upper extremity asymmetry and scoliosis. Similar musculoskeletal abnormalities have been reported in patients with phacomatosis pigmentovascularis and phacomatosis pigmentokeratotica which feature speckled lentiginous nevus; however, this patient demonstrates striking musculoskeletal abnormalities in the absence of coexisting vascular lesions or nevus sebaceous. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 3, 2009 Category: Dermatology Authors: Paras Ramolia, Patricia Treadwell, Anita Haggstrom Source Type: journals

Morphea, Diabetes Mellitus Type I, and Celiac Disease: Case Report and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: An 11-year-old girl with a history of diabetes mellitus type I and celiac disease presented with multiple, depressed patches of purple-brown skin on the right lower extremity and central back, with histopathologic features of early morphea. Though morphea may coexist with other autoimmune diseases, its presentation with both diabetes mellitus type I and celiac disease has not yet been described. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 3, 2009 Category: Dermatology Authors: Elnaz F. Firoz, Hideko Kamino, Thomas J.A. Lehman, Seth J. Orlow Source Type: journals

Knowledge, Attitudes, and Behaviors of Elementary School Students Regarding Sun Exposure and Skin CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The aim of this study was to assess baseline knowledge of skin cancer, sun protection practices, and perceptions of tanning among third through fifth grade elementary students in Florida. A total of 4,002 students in nineteen elementary schools in Palm Beach County, Florida were surveyed. SunSmart America[trade] curriculum pretest responses were the main outcome measures. Overall students' knowledge using a students' mean knowledge scale scores of skin cancer and sun protection were low ( (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 3, 2009 Category: Dermatology Authors: Panta Rouhani, Yisrael Parmet, Ann G. Bessell, Tamika Peay, Alina Weiss, Robert S. Kirsner Source Type: journals

Familial Auriculotemporal Nerve (Frey) SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe two Caucasian sisters with bilateral Frey syndrome, neither of whom was delivered with forceps assistance, and highlight its distinction from food allergy. Frey syndrome may occur in a familial pattern, and in the absence of a history of perinatal trauma. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 3, 2009 Category: Dermatology Authors: Gomathy Sethuraman, Anthony J. Mancini Source Type: journals

Serum Levels of Vascular Endothelial Growth Factor and Basic Fibroblastic Growth Factor in Children with Hemangiomas and Vascular Malformations—Preliminary ReportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here our preliminary results of serum vascular endothelial growth factor and basic fibroblastic growth factor levels as an aid in the diagnosis of hemangiomas and in the follow up of patients with this lesion. Twenty two children with infantile hemangioma (13 with proliferating hemangiomas, nine with involuting lesions), five children with vascular malformations, and 25 healthy children study group. Vascular endothelial growth factor and basic fibroblastic growth factor serum levels were analyzed by an ELISA assay. The serum vascular endothelial growth factor concentrations in children with proliferating hemangio...
Source: Pediatric Dermatology - May 3, 2009 Category: Dermatology Authors: Przemyslaw Przewratil, Anna Sitkiewicz, Krystyna Wyka, Ewa Andrzejewska Source Type: journals

A Newborn with Acanthosis Nigricans: Can It Be Crouzon Syndrome with Acanthosis Nigricans?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a 10-hour-old newborn who presented with bilateral choanal atresia, craniosynostosis and acanthosis nigricans. Molecular tests identified the FGFR3 Ala391Glu substitution confirming the diagnosis of CAN. Of the 35 cases of CAN reported in literature till date, only one child had acanthosis nigricans at birth. This is the first case from India to have been reported with this mutation. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 17, 2009 Category: Dermatology Authors: Sheetal Sharda, Inusha Panigrahi, Kirti Gupta, Sunit Singhi, Rakesh Kumar Source Type: journals

Corticosteroids' Effect on the Height of Atopic Dermatitis Patients: A Controlled Questionnaire StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: To investigate if children treated with topical corticosteroids have a significantly shorter height than the height of children not treated with corticosteroids and to see if corticosteroids affect the ability for treated children to meet growth potential defined as midparental height. Parents of patients attending the UNC's Dermatology clinic completed the survey. The patient's height and siblings' heights were measured by staff. Parents' heights were self reported as were the child's diagnosis of atopic dermatitis, and duration of use of corticosteroids. The patient's height was standardized using CDC charts. A...
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: Meghan W. Thomas, A. T. Panter, Dean S. Morrell Source Type: journals

Childhood Pityriasis RoseaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Pityriasis rosea (PR) is an acute, self-limiting papulosquamous disorder of unknown etiology. Published studies of childhood PR are scarce and most are reviews. The aim of this study was to determine the demographic and clinical features of childhood PR. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: ÖZGE GÜNDÜZ, SIBEL ERSOY-EVANS, AYŞEN KARADUMAN Source Type: journals

Onychomadesis: A Rare Side-Effect of Valproic Acid Medication?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a child with onychomadesis as a possible side-effect of treatment with VPA. Normal nail growth was observed after stopping VPA. The pathomechanism of onychomadesis due to VPA treatment remains unclear. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: ANDREA PORETTI, ULRICH LIPS, MARCO BELVEDERE, BERNHARD SCHMITT Source Type: journals

A First Case of Trimethoprim-Sulfamethoxazole Induced Sweet's Syndrome in a ChildEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: Aida Khaled, Monia Kharfi, Becima Fazaa, Monia Kourda, Asma Bouaziz, Sarrah Kastalli, Mohamed Ridha Kamoun Source Type: journals

Experience with Cyclosporine in Children with Chronic Idiopathic UrticariaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our experience in children is consistent with a previous controlled clinical trial in adults and supports the efficacy and safety of cyclosporine for CIU. However, we recommend that it be reserved for those whose CIU that is resistant to conventional measures and that patients be carefully monitored with cyclosporine serum concentrations and measures of renal function. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: Devang R. Doshi, Miles M. Weinberger Source Type: journals

Retrospective Analysis of 32 Pediatric Patients with Anticonvulsant Hypersensitivity Syndrome (ACHSS)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The ACHSS is a distinct clinical entity which may occur in pediatric patients treated with anticonvulsants, and may have potentially life-threatening consequences. Involvement of multiple organ systems, including the hematologic, hepatic, renal, and pulmonary systems was common. Treatment varied widely, but ranged from supportive care to systemic corticosteroids. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 9, 2009 Category: Dermatology Authors: Brandon D. Newell, Maryam Moinfar, Anthony J. Mancini, Amy Jo Nopper Source Type: journals

Congenital Disseminated Pyogenic GranulomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report two newborns with congenital disseminated PG who were otherwise healthy. In both of these cases, negative GLUT-1 staining supported the proper diagnosis. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 7, 2009 Category: Dermatology Authors: John C. Browning, Karen W. Eldin, Harry P. W. Kozakewich, John B. Mulliken, Alanna F. Bree Source Type: journals

Autosomal Dominant Epidermodysplasia Verruciformis Lacking a Known EVER1 or EVER2 MutationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present epidermodysplasia verruciformis in a father and a son with typical histologic and clinical findings that occur in the absence of mutations in EVER1 or EVER2. Epidermodysplasia verruciformis in this father/son pair in a nonconsanguinous pedigree is consistent with autosomal dominant inheritance. This is the first report of autosomal dominant transmission of epidermodysplasia verruciformis, providing further evidence of the genetic heterogeneity of epidermodysplasia verruciformis. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 2, 2009 Category: Dermatology Authors: David F. McDermott, Bryan Gammon, Peter J. Snijders, Ihunanya Mbata, Beth Phifer, A. Howland Hartley, Chyi-Chia Richard Lee, Philip M. Murphy, Sam T. Hwang Source Type: journals

Knowledge and Perception of Melanocytic Nevi and Sunburn in Young ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Children aged from 6 to 10 years know exactly why they had suffered from sunburn, can describe the sunburn and how to avoid it. They do not feel bothered by their nevi and are alert to the appearance of new nevi. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 2, 2009 Category: Dermatology Authors: Erika Richtig, Erika Jung, Katharina Asbäck, Michael Trapp, Rainer Hofmann-Wellenhof Source Type: journals

Fluocinolone Acetonide 0.01% in Peanut Oil: Safety and Efficacy Data in the Treatment of Childhood Atopic Dermatitis in Infants as Young as 3 Months of AgeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Fluocinolone acetonide 0.01% in a blend of refined peanut and mineral oils has been established as effective and safe treatment for atopic dermatitis in patients 2 years and older, including those with peanut sensitivity, for several years. We sought to study the safety of fluocinolone acetonide 0.01% oil and its potential for adrenal axis suppression in infants as young as 3 months of age. A controlled, open-label study was performed in children aged 3 months to 2 years with moderate to severe atopic dermatitis at two academic pediatric dermatology centers. Patients received topical fluocinolone acetonide 0.01% ...
Source: Pediatric Dermatology - April 2, 2009 Category: Dermatology Authors: Magdalene A. Dohil, Elisabeth Alvarez-Connelly, Lawrence F. Eichenfield Source Type: journals

Systematized Contact Dermatitis and Montelukast in an Atopic BoyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a 9-year-old Caucasian boy with a history of mild atopic dermatitis that experienced severe systematized dermatitis after being started on montelukast chewable tablets containing aspartame. Patch testing revealed multiple chemical sensitivities which included a positive reaction to formaldehyde. Notably, resolution of his systemic dermatitis only occurred with discontinuation of the montelukast chewables. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 2, 2009 Category: Dermatology Authors: Mari Paz Castanedo-Tardan, Mercedes E. González, Elizabeth A. Connelly, Kelly Giordano, Sharon E. Jacob Source Type: journals

A Phase II, Open-Label Study of the Efficacy and Safety of Imiquimod in the Treatment of Superficial and Mixed Infantile HemangiomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Treatment of infants with infantile hemangioma with imiquimod up to seven times per week for 16 weeks was generally well tolerated with low systemic exposure. Improvement was observed in hemangioma coloration, but not lesion size, suggesting effects were limited to the superficial component. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 2, 2009 Category: Dermatology Authors: Catherine C. McCuaig, Josée Dubois, Julie Powell, Claude Belleville, Michèle David, Élisabeth Rousseau, Roxanne Gendron, Fatemeh Jafarian, Isabelle Auger Source Type: journals

Pyogenic Granuloma in Ten Children Treated with Topical ImiquimodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a series of 10 children, highlighting the safety and efficacy of topical 5% Imiquimod as an alternative noninvasive treatment of pyogenic granuloma. Ten children with a mean age of 2.5 years and 10.8 week duration of facial pyogenic granuloma lesion were recruited. Treatment regime with topical Imiquimod 5% cream varied in frequency of application and duration according to clinical response. Clinical outcome in the majority of the children was satisfactory. Three had no evidence of disease and five had small hypopigmented or erythematous lesions which were continuing to improve and more acceptable then a surgical...
Source: Pediatric Dermatology - March 29, 2009 Category: Dermatology Authors: Sara M. Tritton, Saxon Smith, Li-Chuen Wong, Samuel Zagarella, Gayle Fischer Source Type: journals

Lyme Disease as a Cause of Acropapular Dermatitis of ChildhoodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a child with typical findings of acropapular dermatitis of childhood whose serologic workup revealed an acute Lyme infection. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 20, 2009 Category: Dermatology Authors: CAITLIN E. KENNEDY, RAHAT S. AZFAR, PAUL J. HONIG Source Type: journals

Extensive Tinea in a Patient With Severe Combined ImmunodeficiencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We reported a case of SCID which was associated with a widespread skin infection with Trichophyton mentagrophytes. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 18, 2009 Category: Dermatology Authors: RAFAEL JIMÉNEZ-PUYA, C. VÁZQUEZ-BAYO, A. RODRIGUEZ-BUJALDÓN, F. GÓMEZ GARCÍA, JOSÉ CARLOS MORENO-GIMÉNEZ Source Type: journals

Cantharidin Use Among Pediatric Dermatologists in the Treatment of Molluscum ContagiosumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Cantharidin is cited often in the dermatology and pediatric literature as a valuable treatment option for molluscum contagiosum (MC). However, there have been no prospective, randomized, vehicle-controlled trials that have been able to quantify cantharidin's efficacy in MC. The purpose of this study was to determine the breadth of usage of cantharidin, most frequently used protocols, and common side effects seen with use of cantharidin. An eighteen question survey was administered to the Society of Pediatric Dermatology. The survey sought to evaluate treatments used in MC and experiences with cantharidin includin...
Source: Pediatric Dermatology - March 18, 2009 Category: Dermatology Authors: Jacquelyn Coloe, Dean S. Morrell Source Type: journals

Metastatic Cutaneous Crohn's Disease in Children: Case Report and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a 13½-year-old girl whose initial symptom of Crohn's disease was asymptomatic labial swelling. An overview of metastatic cutaneous Crohn's disease in childhood is also provided. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 18, 2009 Category: Dermatology Authors: Susan Keiler, Patrice Tyson, Joan Tamburro Source Type: journals

A Novel Gel Formulation of 0.25% Tretinoin and 1.2% Clindamycin Phosphate: Efficacy in Acne Vulgaris Patients Aged 12 to 18 YearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study reports the efficacy data from the 1,716 12- to 18-year-old adolescents with mild to severe acne included in the trials. The multicenter, double-blind, randomized, vehicle-controlled studies evaluated efficacy by assessing changes in inflammatory, noninflammatory, and total lesion counts over a 12-week study interval. The adolescents treated with CLIN/RA gel had statistically greater reductions in mean inflammatory, noninflammatory, and total lesions than tretinoin, clindamycin, or vehicle. The combination formulation appears efficacious in 12 to 18 year olds and is more effective than the individual constituent...
Source: Pediatric Dermatology - March 18, 2009 Category: Dermatology Authors: Lawrence F. Eichenfield Source Type: journals

Two Pediatric Cases of Primary Cutaneous B-cell Lymphoma and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe two cases of marginal zone primary cutaneous B-cell lymphoma in young boys. Thus far, both have been managed with local therapy. We review the literature of this rare malignancy. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 14, 2009 Category: Dermatology Authors: Victoria Sharon, Patricia S. Mecca, Peter G. Steinherz, Tanya M. Trippett, Patricia L. Myskowski Source Type: journals

5% 5-Fluorouracil Cream for Treatment of Verruca Vulgaris in ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Warts are a common pediatric skin disease. Most treatments show only modest benefit, and some are poorly tolerated because of pain. 5-fluorouracil interferes with deoxyribonucleic acid and ribonucleic acid synthesis, and is used to treat genital warts in adults. Efficacy, safety, and tolerability of topical 5% 5-fluorouracil for treatment of common warts were examined in an open-label pilot study with pediatric patients. Thirty-nine children who have at least two hand warts applied 5% 5-fluorouracil cream (Efudex, Valeant Pharmaceuticals International) once or twice daily, under occlusion for 6 weeks. Assessment ...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Julie Akiko Gladsjo, Alessandra B. Alió Sáenz, James Bergman, Greg Kricorian, Bari B. Cunningham Source Type: journals

The Prevalence, Characteristics of and Risk Factors for Eczema in Belgian SchoolchildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Childhood eczema is common in infants, but its nature and extent during later childhood remains unclear. In this cross-sectional study we examined the prevalence and characteristics of eczema in an unbiased community population of 2,021 Belgian schoolchildren, aged 3.4 to 14.8 years with skin prick testing and parental questionnaires. Our study identified an eczema prevalence of 23.3% and a considerable allergic co-morbidity, mainly in sensitized children. The reported prevalence of eczema in infancy was 18.5% and for current eczema 11.6%. The overall sensitization rate (33.2%) as well as sensitization rates for ...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Elke Govaere, Dirk Van Gysel, Katia M.C. Verhamme, Erenik Doli, Arnold P. Oranje, Frans De Baets Source Type: journals

Gadolinium-Associated Nephrogenic Systemic Fibrosis in a 9-Year-Old BoyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 9-year-old boy on chronic hemodialysis who presented with hyperpigmented, tightly bound-down, indurated plaques of his bilateral lower extremities. Pertinent history included a recent series of magnetic resonance imaging tests utilizing gadolinium-based contrast media. Histopathology showed widened septae with increased fibroblasts and collagen in the subcutis consistent with nephrogenic systemic fibrosis. Nephrogenic systemic fibrosis is a unique fibrosing disorder characterized by skin thickening of the extremities and trunk, resembling that seen in systemic sclerosis. The majority of cases have been report...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Clare Foss, Jeff K. Smith, Luis Ortiz, Coral Hanevold, Loretta Davis Source Type: journals

Acrodermatitis Enteropathica-Like Eruption in Metabolic Disorders: Acrodermatitis Dysmetabolica Is Proposed as a Better TermEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this study, acrodermatitis enteropathica-like eruption was noted in various metabolic disorders, including organic acidemias. We suggest that acrodermatitis dysmetabolica might be a better term for acrodermatitis enteropathica-like eruption occurring secondary to metabolic disorders other than acquired zinc deficiency. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Duru Tabanlıoğlu, Sibel Ersoy-Evans, Ayşen Karaduman Source Type: journals

Clinical Demonstration of Skin Mildness and Suitability for Sensitive Infant Skin of a New Baby WipeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: A cleansing baby wipe with sufficient pH buffering capacity may help to restore the pH balance of skin following exposure to urine and feces in the diaper environment and maintain skin health.Objective: To evaluate the skin effects of a novel baby wipe formulation with increased pH buffering.Subjects and Methods: A series of clinical studies was designed and conducted to evaluate the skin effects of the new baby wipe, including a 21-day cumulative skin irritation patch study in adults (n = 31), a 4-week study in babies with medically confirmed atopic dermatitis (n = 32), a 2-week study comparing skin ...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Ralf Adam, Baerbel Schnetz, Petra Mathey, Marc Pericoi, Yves de Prost Source Type: journals

Premenarchal Vulvar Ulceration: Is Chronic Irritation a Causative Factor?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Girls with vulvar ulcerations who have deny being sexually active should be thoroughly evaluated for infections, Behcet's disease, and other health problems, but, in addition, should be questioned about use of tight-fitting clothing in the perineal area. We hypothesize that chronic irritation because of tight clothing may play a role in causing vulvar ulcerations in this setting. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Fatma Bahar Cebesoy, Ozcan Balat, Serhat Inaloz Source Type: journals

An 18-year-old Male with Severe Bilateral Cataracts and Atopic Dermatitis—A Case Report and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Lisa Mondzelewski, Catherine Hagan, Andrew White Source Type: journals

What Is "High Risk"? A Systematic Review of Atopy Risk and Implications for Primary PreventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Atopic diseases are common and becoming more prevalent. Efforts have focused on primary disease prevention by identifying high-risk children and applying preventative strategies. Our aim was to evaluate methods used to identify high-risk children in atopy prevention studies. A literature search for relevant articles published between 1986 and 2006 was conducted, and all abstracts were reviewed. The search yielded 1,535 publications, 133 were reviewed in detail, and 57 met inclusion criteria. High risk was defined by 30 different methods. First-degree relatives with an atopic disorder were included in all methods,...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Sarah L. Chamlin, Kellee Kaulback, Anthony J. Mancini Source Type: journals

Treatment of Juvenile Pemphigus Vulgaris with Intravenous Immunoglobulin TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the clinical response and follow-up on eight patients with juvenile pemphigus vulgaris treated with intravenous immunoglobulin. Six Caucasian females and two Caucasian males ages 15 to 18 (mean 15.5) were treated with intravenous immunoglobulin based on a published protocol. The indications were lack of response and development of serious side-effects to conventional therapy in four, lack of response to dapsone in two, and parental choice in two patients. In seven patients, a prolonged clinical remission was achieved. They received a mean of 28.5 cycles of intravenous immunoglobulin in a mean of 43.4 months and w...
Source: Pediatric Dermatology - March 11, 2009 Category: Dermatology Authors: Adam Asarch, A. Razzaque Ahmed Source Type: journals

Successful Treatment of Severe Iatrogenic Calcinosis Cutis with Intravenous Sodium Thiosulfate in a Child Affected by T-Acute Lymphoblastic LeukemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 5-year-old boy with acute lymphoblastic leukemia who developed severe calcinosis cutis in the right forearm and hand, and in the left leg and foot after extravasation of calcium gluconate during treatment for tumor-lysis-syndrome-related hypocalcaemia. Surgical debridement, local wound care, hyperbaric oxygen therapy, and sodium thiosulfate infusion achieved a complete healing of all lesions in an eight-month period with a short discontinuation of chemotherapy. No functional or sensitive impairment remained. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - December 12, 2008 Category: Dermatology Authors: Colombatti Raffaella, Calò Annapaola, Iacopetti Tullio, Rosolen Angelo, Lombardi Giuseppe, Cesaro Simone Source Type: journals

Diffuse Nonscarring Alopecia of Scalp: An Indicator of Early Infantile Scurvy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: An infant with diffuse nonscarring alopecia of scalp and radiologic features of scurvy responded dramatically to oral vitamin C therapy. The characteristic cutaneous manifestations of scurvy are usually not seen in infancy. The manifestations of initial stage of scurvy that are not related to collagen synthesis, as in the present case, should alert to the possibility of this potentially fatal condition. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - October 25, 2008 Category: Dermatology Authors: SHIVANNA RAGUNATHA, ARUN C. INAMADAR, APARNA PALIT, VISHWANATH V. SAMPAGAVI, NIRANJAN S. DESHMUKH Source Type: journals