A descriptive epidemiological study on the treatment options for head and neck cancer: Transition before and after approval of cetuximab
ConclusionThis study showed the current practices in concomitant medication used in chemoradiotherapy for HNC patients in Japan, the transition in anticancer drugs used before and after cetuximab approval, and the factors affecting the selection of concomitant drugs. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 23, 2018 Category: Drugs & Pharmacology Authors: Shuhei Yamada, Izumi Sato, Koji Kawakami Tags: ORIGINAL REPORT Source Type: research

Statin use and survival in patients with gastric cancer in two independent population ‐based cohorts
ConclusionsIn two independent UK cohorts, there was some evidence that statin use was associated with reduced cancer ‐specific mortality. However, these associations were weak in magnitude and did not follow a clear dose response, and we cannot rule out confounding by stage. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 20, 2018 Category: Drugs & Pharmacology Authors: Andrew D. Spence, John Busby, Carmel M. Hughes, Brian T. Johnston, Helen G. Coleman, Chris R. Cardwell Tags: ORIGINAL REPORT Source Type: research

Direct oral anticoagulant use and subsequent start of proton pump inhibitors as proxy for gastric complaints
ConclusionsProton pump inhibitor initiation occurred frequently in incident DOAC users but more often in patients treated with dabigatran than in those treated with rivaroxaban or apixaban. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 15, 2018 Category: Drugs & Pharmacology Authors: G. Denise Zielinski, Martina Teichert, Frederikus A. Klok, Frits R. Rosendaal, Menno V. Huisman, Suzanne C. Cannegieter, Willem M. Lijfering Tags: ORIGINAL REPORT Source Type: research

Use of tumor necrosis factor ‐alpha inhibitors during pregnancy among women who delivered live born infants
ConclusionThere was a preference for etanercept among pregnancies with AS/JIA/PsA/PsO/RA, despite the availability of other TNFis. Decline in TNFi use after the first trimester may be related to the desire to reduce TNFis transplacental transfer and to minimize infection risk to the fetus or baby associated with live vaccine immunizations after birth. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 14, 2018 Category: Drugs & Pharmacology Authors: Efe Eworuke, Genna Panucci, Margie Goulding, Rosemarie Neuner, Sengwee Toh Tags: ORIGINAL REPORT Source Type: research

Overall and cause ‐specific mortality in the Sentinel system: A power analysis
ConclusionsThis was the first study to investigate mortality data in the Sentinel death tables. We found that all ‐cause mortality appeared well powered for use as a safety outcome and cause‐specific mortality outcomes may be adequately powered in certain circumstances. Further investigation into the quality of the Sentinel death data is needed. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 13, 2018 Category: Drugs & Pharmacology Authors: Richard S. Swain, Lockwood G. Taylor, Tiffany S. Woodworth, Candace C. Fuller, Andrew B. Petrone, Talia J. Menzin, Nicole R. Haug, Sengwee Toh, Andrew D. Mosholder Tags: ORIGINAL REPORT Source Type: research

Increases in controlled ‐release oxycodone utilisation following the subsidy of oxycodone with naloxone formulations: An Australian population‐based study
ConclusionsAfter its subsidy, the uptake of low ‐dose oxycodone/naloxone CR was greater than expected if it were substituting the single‐ingredient oxycodone CR, resulting in an expansion of the oxycodone CR market. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 13, 2018 Category: Drugs & Pharmacology Authors: Andrea L. Schaffer, Emily A. Karanges, Nicholas A. Buckley, Andrew Wilson, Louisa Degenhardt, Briony Larance, Sallie ‐Anne Pearson Tags: ORIGINAL REPORT Source Type: research

“Methotrexate and NSAIDs in rheumatoid arthritis—Confirmation of a known NSAIDs adverse effect rather than a dangerous combination”
Pharmacoepidemiology and Drug Safety, EarlyView. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 13, 2018 Category: Drugs & Pharmacology Authors: Orwah Al ‐Khalili, Ted R. Mikuls, James R. O'Dell, Bryant R. England Tags: LETTER TO THE EDITOR Source Type: research

Predictive model algorithms identifying early and advanced stage ER+/HER2 − breast cancer in claims data
ConclusionWe conducted a validation study and developed predictive models to identify in a claims database cohorts of women with ER+/HER2 − ESBC and ASBC. The models identified large cohorts in the claims data that can be used to characterize indications in the evaluation of targeted therapies. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 9, 2018 Category: Drugs & Pharmacology Authors: Daniel C. Beachler, Cynthia Luise, Ruihua Yin, Kelsey Gangemi, Philip T. Cochetti, Stephan Lanes Tags: ORIGINAL REPORT Source Type: research

Understanding multi ‐pill ingestion of prescription opioids: Prevalence, characteristics, and motivation
ConclusionsThese results indicate that the ingestion of multiple opioid pills/tablets is extremely common among treatment ‐seeking opioid users. This, and other forms of non‐medical oral use of prescription opioids, should be taken under consideration when developing prevention and intervention efforts targeting the opioid epidemic. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 9, 2018 Category: Drugs & Pharmacology Authors: Matthew S. Ellis, Theodore J. Cicero, Richard C. Dart, Jody L. Green Tags: BRIEF REPORT Source Type: research

Diagnostic accuracy of the International Classification of Diseases, Tenth Revision, codes of heart failure in an administrative database
Pharmacoepidemiology and Drug Safety, EarlyView. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 5, 2018 Category: Drugs & Pharmacology Authors: Pauline Bosco ‐Lévy, Stéphanie Duret, François Picard, Pierre Dos Santos, Etienne Puymirat, Véronique Gilleron, Patrick Blin, Gilles Chatellier, Vincent Looten, Nicholas Moore Source Type: research

Generation of a pregnancy cohort for medicine utilisation and medicine safety studies in New Zealand
Pharmacoepidemiology and Drug Safety, EarlyView. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 5, 2018 Category: Drugs & Pharmacology Authors: Sarah Donald, David Barson, Simon Horsburgh, Katrina Sharples, Lianne Parkin Source Type: research

Issue Information
Pharmacoepidemiology and Drug Safety,Volume 27, Issue 11, Page 1293-1293, November 2018. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 5, 2018 Category: Drugs & Pharmacology Source Type: research

Issue Information
Pharmacoepidemiology and Drug Safety,Volume 27, Issue 11, Page 1-4, November 2018. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - November 5, 2018 Category: Drugs & Pharmacology Source Type: research

Who diagnosed and prescribed what? Using provider details to inform observational research
Pharmacoepidemiology and Drug Safety, EarlyView. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - October 31, 2018 Category: Drugs & Pharmacology Authors: Greta A. Bushnell, Til St ürmer, Christina Mack, Virginia Pate, Matthew Miller Source Type: research

Assessment of prior opioid tolerance among new users of fentanyl transdermal system in FDA's Sentinel System
Pharmacoepidemiology and Drug Safety, EarlyView. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - October 31, 2018 Category: Drugs & Pharmacology Authors: Noelle M. Cocoros, Marc R. Larochelle, Jennifer Popovic, Andrew B. Petrone, Cynthia Kornegay, Jing Ju, Judith A. Racoosin Source Type: research