Retraction Note: Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular A β1-42 rat model of Alzheimer's disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway
Pharmacol Rep. 2023 Jul 21. doi: 10.1007/s43440-023-00511-2. Online ahead of print.NO ABSTRACTPMID:37477845 | DOI:10.1007/s43440-023-00511-2 (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 21, 2023 Category: Drugs & Pharmacology Authors: Noorul Hasan Saima Zameer Abul Kalam Najmi Suhel Parvez Mohammad Shahar Yar Mohd Akhtar Source Type: research

Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem mass spectrometry analytical method development, cross-validation, and clinical application
CONCLUSIONS: This study is the first development of a triple matrix-based LC-MS/MS method for MPA determination in the pediatric population after renal transplantation. For the first time, the developed methods were cross-validated with routinely used HPLC-DAD protocol.PMID:37452967 | DOI:10.1007/s43440-023-00509-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 15, 2023 Category: Drugs & Pharmacology Authors: Arkadiusz Kocur Jacek Rubik Pawe ł Czarnowski Agnieszka Czajkowska Dorota Marsza łek Maciej Sierakowski Marta G órska Tomasz Pawi ński Source Type: research

Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem mass spectrometry analytical method development, cross-validation, and clinical application
CONCLUSIONS: This study is the first development of a triple matrix-based LC-MS/MS method for MPA determination in the pediatric population after renal transplantation. For the first time, the developed methods were cross-validated with routinely used HPLC-DAD protocol.PMID:37452967 | DOI:10.1007/s43440-023-00509-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 15, 2023 Category: Drugs & Pharmacology Authors: Arkadiusz Kocur Jacek Rubik Pawe ł Czarnowski Agnieszka Czajkowska Dorota Marsza łek Maciej Sierakowski Marta G órska Tomasz Pawi ński Source Type: research

Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem mass spectrometry analytical method development, cross-validation, and clinical application
CONCLUSIONS: This study is the first development of a triple matrix-based LC-MS/MS method for MPA determination in the pediatric population after renal transplantation. For the first time, the developed methods were cross-validated with routinely used HPLC-DAD protocol.PMID:37452967 | DOI:10.1007/s43440-023-00509-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 15, 2023 Category: Drugs & Pharmacology Authors: Arkadiusz Kocur Jacek Rubik Pawe ł Czarnowski Agnieszka Czajkowska Dorota Marsza łek Maciej Sierakowski Marta G órska Tomasz Pawi ński Source Type: research

Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem mass spectrometry analytical method development, cross-validation, and clinical application
CONCLUSIONS: This study is the first development of a triple matrix-based LC-MS/MS method for MPA determination in the pediatric population after renal transplantation. For the first time, the developed methods were cross-validated with routinely used HPLC-DAD protocol.PMID:37452967 | DOI:10.1007/s43440-023-00509-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 15, 2023 Category: Drugs & Pharmacology Authors: Arkadiusz Kocur Jacek Rubik Pawe ł Czarnowski Agnieszka Czajkowska Dorota Marsza łek Maciej Sierakowski Marta G órska Tomasz Pawi ński Source Type: research

Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem mass spectrometry analytical method development, cross-validation, and clinical application
CONCLUSIONS: This study is the first development of a triple matrix-based LC-MS/MS method for MPA determination in the pediatric population after renal transplantation. For the first time, the developed methods were cross-validated with routinely used HPLC-DAD protocol.PMID:37452967 | DOI:10.1007/s43440-023-00509-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - July 15, 2023 Category: Drugs & Pharmacology Authors: Arkadiusz Kocur Jacek Rubik Pawe ł Czarnowski Agnieszka Czajkowska Dorota Marsza łek Maciej Sierakowski Marta G órska Tomasz Pawi ński Source Type: research

Tanshinone IIA targeting cell signaling pathways: a plausible paradigm for cancer therapy
Pharmacol Rep. 2023 Jul 13. doi: 10.1007/s43440-023-00507-y. Online ahead of print.ABSTRACTNatural compounds originating from plants offer a wide range of pharmacological potential and have traditionally been used to treat a wide range of diseases including cancer. Tanshinone IIA (Tan IIA), a bioactive molecule found in the roots of the Traditional Chinese Medicine (TCM) herb Salvia miltiorrhiza, has been shown to have remarkable anticancer properties through several mechanisms, such as inhibition of tumor cell growth and proliferation, metastasis, invasion, and angiogenesis, as well as induction of apoptosis and autophagy...
Source: Pharmacological Reports - July 13, 2023 Category: Drugs & Pharmacology Authors: Syed Sahajada Mahafujul Alam Arijit Samanta Faizan Uddin Safdar Ali Mehboob Hoque Source Type: research

Tanshinone IIA targeting cell signaling pathways: a plausible paradigm for cancer therapy
Pharmacol Rep. 2023 Jul 13. doi: 10.1007/s43440-023-00507-y. Online ahead of print.ABSTRACTNatural compounds originating from plants offer a wide range of pharmacological potential and have traditionally been used to treat a wide range of diseases including cancer. Tanshinone IIA (Tan IIA), a bioactive molecule found in the roots of the Traditional Chinese Medicine (TCM) herb Salvia miltiorrhiza, has been shown to have remarkable anticancer properties through several mechanisms, such as inhibition of tumor cell growth and proliferation, metastasis, invasion, and angiogenesis, as well as induction of apoptosis and autophagy...
Source: Pharmacological Reports - July 13, 2023 Category: Drugs & Pharmacology Authors: Syed Sahajada Mahafujul Alam Arijit Samanta Faizan Uddin Safdar Ali Mehboob Hoque Source Type: research

Tanshinone IIA targeting cell signaling pathways: a plausible paradigm for cancer therapy
Pharmacol Rep. 2023 Jul 13. doi: 10.1007/s43440-023-00507-y. Online ahead of print.ABSTRACTNatural compounds originating from plants offer a wide range of pharmacological potential and have traditionally been used to treat a wide range of diseases including cancer. Tanshinone IIA (Tan IIA), a bioactive molecule found in the roots of the Traditional Chinese Medicine (TCM) herb Salvia miltiorrhiza, has been shown to have remarkable anticancer properties through several mechanisms, such as inhibition of tumor cell growth and proliferation, metastasis, invasion, and angiogenesis, as well as induction of apoptosis and autophagy...
Source: Pharmacological Reports - July 13, 2023 Category: Drugs & Pharmacology Authors: Syed Sahajada Mahafujul Alam Arijit Samanta Faizan Uddin Safdar Ali Mehboob Hoque Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research

Pharmacovigilance in the Caribbean Countries: an Overview
Curr Pharmacol Rep. 2023 May 18:1-11. doi: 10.1007/s40495-023-00320-4. Online ahead of print.ABSTRACTPURPOSE OF OVERVIEW: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such produ...
Source: Pharmacological Reports - June 26, 2023 Category: Drugs & Pharmacology Authors: Kingsley E W Walker Reshma Bankay Satish Jankie Sameer Dhingra Source Type: research