Effect of bisphosphonates and statins on the in vitro radiosensitivity of breast cancer cell lines
CONCLUSIONS: Our findings show that pretreatment with ZOPRA can decrease the radioresistance of breast cancer cells at the molecular and cellular levels. The fact that ZOPRA was previously shown to radioprotect normal tissues, makes it a good candidate to become a therapeutic window-widening drug.PMID:38151641 | DOI:10.1007/s43440-023-00560-7 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 27, 2023 Category: Drugs & Pharmacology Authors: Larry Bodgi Jolie Bou-Gharios Joyce Azzi Rafka Challita Charbel Feghaly Khanom Baalbaki Hussein Kharroubi Fatima Chhade Fady Geara Wassim Abou-Kheir Zeina Ayoub Source Type: research

Weighted gene co-expression network analysis for hub genes in colorectal cancer
CONCLUSIONS: CLCA1, CLCA4, and CPT1A express at low levels in CRC and function as core anti-tumor genes. As a gene set, they can predict prognosis well.PMID:38150140 | DOI:10.1007/s43440-023-00561-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 27, 2023 Category: Drugs & Pharmacology Authors: Zheng Xu Jianing Wang Guosheng Wang Source Type: research

Effect of bisphosphonates and statins on the in vitro radiosensitivity of breast cancer cell lines
CONCLUSIONS: Our findings show that pretreatment with ZOPRA can decrease the radioresistance of breast cancer cells at the molecular and cellular levels. The fact that ZOPRA was previously shown to radioprotect normal tissues, makes it a good candidate to become a therapeutic window-widening drug.PMID:38151641 | DOI:10.1007/s43440-023-00560-7 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 27, 2023 Category: Drugs & Pharmacology Authors: Larry Bodgi Jolie Bou-Gharios Joyce Azzi Rafka Challita Charbel Feghaly Khanom Baalbaki Hussein Kharroubi Fatima Chhade Fady Geara Wassim Abou-Kheir Zeina Ayoub Source Type: research

Weighted gene co-expression network analysis for hub genes in colorectal cancer
CONCLUSIONS: CLCA1, CLCA4, and CPT1A express at low levels in CRC and function as core anti-tumor genes. As a gene set, they can predict prognosis well.PMID:38150140 | DOI:10.1007/s43440-023-00561-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 27, 2023 Category: Drugs & Pharmacology Authors: Zheng Xu Jianing Wang Guosheng Wang Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research