Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research

Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research

Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research

Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research

Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research

Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research

Do Longer Exhalations Increase HRV During Slow-Paced Breathing?
Appl Psychophysiol Biofeedback. 2024 Mar 20. doi: 10.1007/s10484-024-09637-2. Online ahead of print.ABSTRACTSlow-paced breathing at an individual's resonance frequency (RF) is a common element of heart rate variability (HRV) biofeedback training (Laborde et al. in Psychophysiology 59:e13952, 2022). Although there is strong empirical support for teaching clients to slow their respiration rate (RR) to the adult RF range between 4.5 and 6.5 bpm (Lehrer & Gevirtz, 2014), there have been no definitive findings regarding the best inhalation-to-exhalation (IE) ratio to increase HRV when breathing within this range. Three meth...
Source: Physiological Research - March 20, 2024 Category: Physiology Authors: Zachary M Meehan Fred Shaffer Source Type: research

Health-promoting benefits of lentils: Anti-inflammatory and anti-microbial effects
Curr Res Physiol. 2024 Mar 5;7:100124. doi: 10.1016/j.crphys.2024.100124. eCollection 2024.ABSTRACTThis paper describes how lentils (Lens culinaris species) can positively affect health by reducing inflammation, providing antioxidants, and displaying antimicrobial properties. Lentils are rich in proteins, essential amino acids, minerals, and fibers, making them a valuable source of nutrition, particularly in low and middle-income countries. Lentils have many health benefits, including positive effects on diabetes management, support for cardiovascular health, and antioxidative properties. The antioxidative properties of le...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Rachel Alexander Abdullah Khaja Nicholas Debiec Alex Fazioli Mary Torrance Mohammed S Razzaque Source Type: research

Investigating the role of CFTR in human and mouse myometrium
CONCLUSION: These results demonstrate decreased myometrial function when CFTR is inhibited, which may have implications on pregnancy and labour outcome and therapeutic decisions for labour in CF patients.PMID:38501132 | PMC:PMC10945125 | DOI:10.1016/j.crphys.2024.100122 (Source: Physiological Research)
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Clodagh Prendergast Susan Wray Daniella Dungate Christine Martin Andra Vaida Elizabeth Brook Cecilia Ani Chioma Helen Wallace Source Type: research

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire
Exp Physiol. 2024 Mar 19. doi: 10.1113/EP091784. Online ahead of print.ABSTRACTMany animal species do not breathe in a continuous, rhythmic fashion, but rather display a variety of breathing patterns characterized by prolonged periods between breaths (inter-breath intervals), during which the heart continues to beat. Examples of intermittent breathing abound across the animal kingdom, from crustaceans to cetaceans. With respect to human physiology, intermittent breathing-also termed 'periodic' or 'episodic' breathing-is associated with a variety of pathologies. Cardiovascular phenomena associated with intermittent breathin...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Warren Burggren Andreas Fahlman William Milsom Source Type: research