Persons with allergy symptoms use alternative medicine more often.
CONCLUSIONS: The occurrence of allergic diseases and asthma influences the frequency of alternative medicine use. However the frequency of alternative medicine use does not depend on allergic disease or asthma being confirmed by a doctor. PMID: 27672066 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kłak A, Raciborski F, Krzych-Fałta E, Opoczyńska-Świeżewska D, Szymański J, Lipiec A, Piekarska B, Sybilski A, Tomaszewska A, Samoliński B Tags: Pneumonol Alergol Pol Source Type: research

Effect of obesity and metabolic syndrome on severity, quality of life, sleep quality and inflammatory markers in patients of asthma in India.
CONCLUSIONS: The present study has shown that obese asthmatics especially with metabolic syndrome represent a subtype of asthmatic population. Hence, the treatment of metabolic syndrome may be necessary in addition to asthma to achieve optimal control. PMID: 27672067 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Singh M, Gupta N, Kumar R Tags: Pneumonol Alergol Pol Source Type: research

Centrilobular nodules in high resolution computed tomography of the lung in IPAH patients - preliminary data concerning clinico-radiological correlates.
CONCLUSION: Centrilobular nodules in IPAH were combined with lack of PFO, higher mRAP and younger age of patients. PMID: 27672068 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Szturmowicz M, Kacprzak A, Burakowska B, Skoczylas A, Bestry I, Kuś J, Fijałkowska A, Torbicki A, Kurzyna M Tags: Pneumonol Alergol Pol Source Type: research

The incidence of tuberculosis transmission among family members and outside households.
CONCLUSIONS: The analysis confirmed the transmission of tuberculosis among members of 53 families. In the remaining 6 families the source of infection were people outside the households. In all families with young children, strains isolated from them have identical DNA patterns as strains obtained from their adult caregivers. To confirm the transmission of TB in the study population of patients, epidemiological analysis required the addition of a genotyping methods characterised by high discriminatory power. PMID: 27672069 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kozińska M, Augustynowicz-Kopeć E Tags: Pneumonol Alergol Pol Source Type: research

Musculosceletal tuberculosis with involvement of tendon sheaths and formation of synovial cyst.
We present a case of patient on immunosuppressive therapy due to myositis, in whom we diagnosed musculoskeletal tuberculosis in form of involvement of tendon sheath and formation of synovial cyst. PMID: 27672070 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Zieliński M, Mazur-Zielińska H, Kozielski J Tags: Pneumonol Alergol Pol Source Type: research

Hemoptysis in a patient with multifocal primary pulmonary angiosarcoma.
We present a case report of 70 year-old man, active cigarette-smoker, with a 2-month history of non-massive hemoptysis. The thorax CT revealed several solid pulmonary nodules surrounded by areas of ground glass opacity. As bronchoscopy failed to deliver adequate tissue samples, video assisted thoracic surgery (VATS) with pleura and lung biopsy was necessary. Histopathological findings were consistent with pulmonary angiosarcoma. Since no extrapulmonary lesions were demonstrated, the final diagnosis of primary pulmonary angiosarcoma was made. The patient died three months after the onset of symptoms. Our case report highlig...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Piechuta A, Przybyłowski T, Szołkowska M, Krenke R Tags: Pneumonol Alergol Pol Source Type: research

The role of the TGF-SMAD signalling pathway in the etiopathogenesis of severe asthma.
Abstract Asthma is a chronic inflammatory heterogeneous disease of the lower respiratory tract characterised by the occurrence of bronchial hyper-responsiveness and paroxysmal, changeable bronchial obstruction. Transforming growth factor-beta (TGF-b) is one of the cytokines involved in mediating airway inflammation and remodelling. The level of TGF-b1 gene expression correlates with severity of symptoms. Alterations in the main SMAD signal transmission, overexpression of TGF-b genes and changes in the transcriptome cause excessive secretion of TGF-b and its increased expression in target cells, which clini...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Koćwin M, Jonakowski M, Przemęcka M, Zioło J, Panek M, Kuna P Tags: Pneumonol Alergol Pol Source Type: research

Obstructive sleep apnea syndrome and hypothyroidism - merely concurrence or causal association?
Abstract The prevalence of obstructive sleep apnea-hypopnea syndrome (OSAHS) ranges from 4 to 7% in men and from 2 to 5% in women. Its deleterious consequences such as traffic accidents, cardiovascular complications increasing morbidity and mortality, make it a major health problem. Apart from obesity (a major risk factor for OSAHS), hypothyroid patients are prone to reveal this phenotype. Although hypothyroidism seems an acknowledged risk factor for OSAHS, some authors report the lack of clinically relevant association. The argument partly depends on the increased prevalence of hypothyroidism in OSAHS pat...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kuczyński W, Gabryelska A, Mokros Ł, Białasiewicz P Tags: Pneumonol Alergol Pol Source Type: research

Chronic obstructive pulmonary disease in Poland - a need for population-based epidemiological studies.
PMID: 27435345 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Zejda J, Brożek G Tags: Pneumonol Alergol Pol Source Type: research

Quality of life in adults with cystic fibrosis: the Greek experience.
CONCLUSION: More than half Greek adult CF patients report that they are capable to participate in social activities but most of them are worried about the outcome of their disease and its effect on their lives. PMID: 27435346 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Stofa M, Xanthos T, Ekmektzoglou K, Chalkias A, Barouxis D, Pantazopoulos I, Iacovidou N Tags: Pneumonol Alergol Pol Source Type: research

Effects of depression and anxiety on asthma-related quality of life.
CONCLUSIONS: Anxiety and depression are found in asthma patients, with higher severity observed in patients with uncontrolled asthma. Female gender, the level of asthma control, asthma severity, smoking, as well as diagnoses of anxiety and depression are predictors of a significantly lower quality of life in asthma. PMID: 27435347 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Lomper K, Chudiak A, Uchmanowicz I, Rosińczuk J, Jankowska-Polanska B Tags: Pneumonol Alergol Pol Source Type: research

Can pancreatic tissue cause haemoptysis?
Abstract A mature teratoma is a tumour of primary germ cells. It is often found in the mediastinum. The authors describe a case of a young man who demonstrated haemoptysis as the only symptom of a mediastinal tumour. The tumour was removed operatively, sent for histopathological examination and immunohistochemistry. The removed tumour was a mature teratoma including elements of the pancreas. The authors revealed the presence of trypsin in the pancreatic acinar cells. The proteolytic activity of the tumour was taken as the cause of haemoptysis because of enzymatic erosion of lung tissue intimately attached ...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Bubel A, Rogoziński P, Bruliński K Tags: Pneumonol Alergol Pol Source Type: research

The pharmaceutical care in asthma - Polish and global perspective.
Abstract The pharmaceutical care is a pharmacist's contribution to the care of individual patients and leads to optimize the use of drugs. The pharmaceutical care may improve adherence, clinical effectiveness of providing therapy and improve the health-related quality of life. The conducted literature review confirmed that pharmaceutical care and advanced pharmaceutical services are clinical effective in asthma. The implementation of pharmaceutical care under Polish conditions is currently insufficient and remains challenging for the future. Herein we should admit, that the polish government has recently p...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Swieczkowski D, Poniatowski P, Merks P, Jaguszewski M Tags: Pneumonol Alergol Pol Source Type: research

The effect of omalizumab on eosinophilic inflammation of the respiratory tract in patients with allergic asthma.
Abstract Bronchial asthma is characterised by high levels of immunoglobulin E (IgE) and overproduction of pro-inflammatory cytokines, including interleukins IL-4, IL-13 and IL-5 needed for, amongst other things, the production of IgE and the differentiation, maturation, migration and survival of eosinophils. Eosinophils are one of the most important cells in allergic inflammation. Their presence in tissue is linked to the persistence of inflammatory infiltrate, tissue damage and remodelling. Although these cells are very sensitive to corticosteroids, some asthmatic patients do not respond to high doses of ...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Kupryś-Lipińska I, Molińska K, Kuna P Tags: Pneumonol Alergol Pol Source Type: research

Fatigue syndrome in sarcoidosis.
Abstract Sarcoidosis is an inflammatory disease of unknown etiology. Most commonly it results in the formation of non-caseating granulomas in intrathoracic lymph nodes and lung parenchyma, but the clinical course and picture may be complicated by extrapulmonary involvement and many non-respiratory signs and symptoms which are directly related to the disease. In addition, sarcoidosis patients may suffer from a plethora of symptoms of uncertain or unknown origin. Fatigue is one of these symptoms, and according to some authors it is reported by the majority of patients with active sarcoidosis, but also by a s...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Górski W, Piotrowski WJ Tags: Pneumonol Alergol Pol Source Type: research