Practical Diabetes International
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Orlistat
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: M Hall, M Fisher, G McKay Tags: Drug Notes Source Type: journals
Delivery of U-500 insulin by CSII in a patient with type 2 diabetes and extreme insulin resistance
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We present a case of extreme insulin resistance in a female patient whose glycaemic control improved remarkably using insulin pump. She also reported subjective improvement in her quality of life. Copyright © 2009 John Wiley & Sons. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: V Hundia, A Pettit, R Pope, J Egerton Tags: Case Reports Source Type: journals
News
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Tags: News Source Type: journals
The Diabetes Foot Care Master Class
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: CD Wroe Tags: Conference Source Type: journals
Severe reversible chorea complicating non-ketotic hyperglycaemia
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We report the case of an 87-year-old lady who presented with chorea complicating non-ketotic hyperglycaemia, and this was confirmed with MRI brain imaging demonstrating the classical feature of this condition. A high T1-weighted signal in the putamen is quite characteristic of this condition. Copyright © 2009 John Wiley & Sons. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: V Chikthimmah, C Hopkins, P Wai, C Soh, M Silverdale Tags: Case Reports Source Type: journals
Successful treatment of diabetic autonomic diarrhoea with monthly subcutaneous lanreotide
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A 29-year-old woman, with 15 years of poorly controlled type 1 diabetes and established diabetic autonomic diarrhoea, presented with worsening diarrhoea and diabetic ketoacidosis. Frequency of bowel opening was up to 40 times per 24 hours. Octreotide was started, rapidly decreasing bowel motion frequency. Due to previous intolerable side effects of rotten odour breath and flatus, she converted to once-monthly subcutaneous lanreotide (Somatuline Autogel). Her diarrhoea remained controlled without any side effects, until her demise a year later from severe diabetic ketoacidosis.To our knowledge this is the first published re...
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: TJ Ulahannan, A Amaratunga Tags: Case Reports Source Type: journals
The current state of general practicediabetes care in the West of Ireland
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This study aimed to assess the care provided to patients with diabetes in general practices in the West of Ireland. A postal questionnaire was sent to all 103 general practices in County Galway. The questionnaire assessed diabetes prevalence and maintenance of a diabetes register, use of guidelines for the care of diabetes, appointments systems and the provision of specialised diabetes clinics in general practice, referrals to the hospital specialist team, and opportunities for developing diabetes care.The response rate was 76%. Mean estimated prevalence of diabetes was 2.7% (range 0.1-9.5%). A diabetes register was mainta...
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: DS Evans, E O'Connell, M O'Donnell, L Hurley, M Glacken, AW Murphy, SF Dinneen Tags: Original Articles Source Type: journals
Understanding, knowledge and attitudes towards current UK driving advice in insulin treated diabetic patients
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UK driving licences are issued and controlled by a government body, the DVLA (Driver and Vehicle Licensing Agency). Diabetic drivers must inform the DVLA and their motor insurer about their condition. Current advice is to test the capillary blood glucose level before driving. If symptomatic hypoglycaemia occurs during driving, the driver should stop, take carbohydrate, and wait 45 minutes after euglycaemia to allow brain function to recover before driving on. Previous studies have shown that diabetic drivers are good at informing both the DVLA and their insurer, but not good at following advice regarding testing and hypogl...
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: DMS Bodansky, HJ Bodansky Tags: Original Articles Source Type: journals
Principles of safe driving on insulin: the message is still not getting across
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: K Shaw Tags: Commentaries Source Type: journals
What has QoF ever done for diabetes?
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 26, 2009 Category: Endocrinology Authors: R Gadsby Tags: Leaders Source Type: journals
Swine flu and diabetes
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 1, 2009 Category: Endocrinology Authors: K Shaw Tags: Leaders Source Type: journals
Ivabradine
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: M Reed, G McKay, M Fisher Tags: Drug Notes Source Type: journals
Preconception care in people with knowndiabetes and those at risk in primary care
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: Steve Chaplin Tags: Conference Source Type: journals
Forward to the past: quality and audit for diabetes in primary care for the 21st century
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: J Richards Tags: State of the Art Lectures Source Type: journals
Polypharmacy in diabetes and solutions for greater adherence
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: Lubna Kerr Tags: Personal Comments Source Type: journals
Marked improvement in glycaemic control in a type 2 diabetes patient following a liver transplant for cirrhotic steatohepatitis
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We present the case of a 58-year-old woman with poorly controlled, insulin-treated type 2 diabetes mellitus who underwent a liver transplant for cirrhosis due to non-alcoholic fatty liver disease complicated by encephalopathy and portal hypertension. Within four months of surgery she exhibited marked improvement in insulin sensitivity, as evidenced by reduced exogenous insulin requirement, with cessation of insulin therapy at 11 months and a consequent dramatic improvement in glycaemic control, eventually achieving an optimal glycosylated haemoglobin concentration on no specific diabetes treatment aside from dietary advice...
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: V Parker, M Smith Tags: Case Reports Source Type: journals
Patients' preference for subsequent therapy following secondary failure of metformin and sulphonylurea
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We surveyed 205 type 2 diabetic patients with glycated haemoglobin 7.5-10.0% on maximum metformin and sulphonylurea to determine their choice for further glycaemic therapy. In all, 54.6% of patients requested pioglitazone, 21.9% basal insulin, and 23.4% preferred exenatide. South Asians generally preferred non-injectables, and more overweight patients preferred exenatide.Despite physician preference for insulin, most patients prefer additional oral agents over injectables. Copyright © 2009 John Wiley & Sons, Ltd. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: H Khan, FM Coyle, TA Chowdhury Tags: Original Short Reports Source Type: journals
A tribute to Dr Ken MacLeod
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: Ken Shaw Tags: Anniversary Reviews Source Type: journals
Is diabetes a disease for general practice?
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: PRW Tasker Tags: Anniversary Reviews Source Type: journals
JDRF News Column
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Tags: JDRF News Source Type: journals
News update
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Tags: Diabetes UK News Source Type: journals
Diabetes care in general practice 25 years on: key developments and the future
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: PRW Tasker Tags: Commentaries Source Type: journals
Genetic testing clarifies diagnosis and treatment in a family with both HNF1A and type 1 diabetes
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Confirming a diagnosis of diabetes may often be straightforward but identifying the actual type of diabetes may not always be obvious, particularly in those with a family history of diabetes. Use of non-genetic tests, such as pancreatic antibodies, may assist in the classification of diabetes but is not routine practice. The introduction of molecular genetic testing may confirm a diagnosis of monogenic diabetes but may be considered by some health care professionals to be expensive and unnecessary, particularly if treatment change is unlikely. However, a positive genetic result may lead to successful transfer from insulin ...
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: M Shepherd Tags: Original Articles Source Type: journals
IFCC standardised HbA1c - a paradigm shift
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: Sath Nag Tags: Letters Source Type: journals
Metformin and anaemia: myth or reality?
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This study set out to determine if there is an association between metformin treatment and anaemia in a large population with diabetes mellitus.A total of 520 consecutive patients with diabetes were studied. Anaemia was defined by World Health Organization criteria of Hb (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: OR Adetunji, H Mani, C Morgan, GV Gill Tags: Original Short Reports Source Type: journals
Patients' understanding is the key to effective communication
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: J Murfin, O Hulson, C Rajeswaran Tags: Diabetes Vignette Source Type: journals
ABCD response to possible link between risk of cancer and use of insulin glargine
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Tags: Position Statements Source Type: journals
Shared practice: integrating diabetes care
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: M Rossi Tags: Diabetes UK Initiative Source Type: journals
Insulin glargine and cancer: cause and effect unproven
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2009 Category: Endocrinology Authors: DR Owens, J Rosenstock, GB Bolli Tags: Leaders Source Type: journals
Rimonabant
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: A Anderson, M Fisher, G McKay Tags: Drug Notes Source Type: journals
Glibenclamide controls ketosis-prone diabetes in a 38-year-old woman with Kir6.2 mutation
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We report the case of a patient with KCNJ11 S3C mutation, who is the oldest patient with neonatal diabetes to have successfully transferred from insulin to sulphonylureas. She was diagnosed with diabetes at the age of four and was treated as having type 1 diabetes mellitus. Her glycaemic control was always sub-optimal; she had had several admissions with diabetic ketoacidosis. Her daughter who developed diabetes at six weeks was found to have neonatal diabetes, which led to her genetic testing. Our patient was also diagnosed with the same KCNJ11 mutation as her daughter. At 38 years of age, after outpatient assessment, she...
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: B Jose, U Griffiths, T Barrett PhD, AT Hattersley, JJ Milles Tags: Case Reports Source Type: journals
News
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Tags: News Source Type: journals
What do women with diabetes know about pregnancy and contraception?
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In conclusion, two-thirds of women of child bearing age were unable to recall having had a discussion regarding pregnancy or contraception. There was poor understanding of the risks associated with pregnancy. A previous pregnancy and antenatal care did not improve knowledge. New educational strategies for preconceptual care are needed for women with diabetes, regardless of parity. Copyright © 2009 John Wiley & Sons, Ltd. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: A Cartwright, M Wallymahmed, I Macfarlane, I Casson Tags: Original Articles Source Type: journals
Primary care, secondary care or both: is there a consensus on long term management of diabetes mellitus?
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The aim of this study was to test the hypothesis that specific referral guidelines are unhelpful because of wide variations in individual clinical practice.A series of representative diabetes case studies were given to a group of primary care, general practice (GP) clinicians for comment. The same cases were given to a group of secondary care clinicians. The suggested management strategies were compared.Overall the results show very little agreement among either primary care or secondary care clinicians for a series of commonly presenting clinical cases. Approximately a third of GP responses for each group of cases suggest...
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: DE Flanagan, A Craig, PJ English Tags: Original Articles Source Type: journals
Management of people with diabetes as emergency medical admissions to hospital
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: Alison E Honan, John W Foote, Brian M Frier Tags: Original Papers Source Type: journals
Mindfulness Based Stress Reduction: effect on emotional distress in diabetes
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Psychological distress is common in patients with diabetes. Little is known about the impact of Mindfulness Based Stress Reduction (MBSR), a non-traditional, cognitive behavioural intervention designed to improve stress management skills, in patients with diabetes.The purpose of this retrospective analysis was to evaluate the impact of MBSR training on mood states in 25 individuals with diabetes. All participants completed the Profile of Mood States Short Form (POMS-SF) at baseline and following eight weeks of MBSR. Overall psychological distress measured by the total mood score (TMS) and six subscales - including tension/...
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: LA Young, AR Cappola, MJ Baime Tags: Original Short Reports Source Type: journals
Is mindfulness based training a cognitive behaviour technique?
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: Katarzyna M Zinken Tags: Commentaries Source Type: journals
Sinus headache with diabetic ketoacidosis
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: E-K Reed, P Davison, PJ Murphy, S Croxson Tags: Diabetes Vignette Source Type: journals
Practice-based commissioning in type 2 diabetes management: a successful joint health care practice/industry working model
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: M Davis, D Kane Tags: Leaders Source Type: journals
Clinical research in diabetes: a practical resource to assist with participant understanding and recruitment
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 3, 2009 Category: Endocrinology Authors: DR Matthews, P Chester, ED Kennedy, K Winkley Tags: Leaders Source Type: journals
Gabapentin
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: A MacEwan, G McKay, M Fisher Tags: Drug Notes Source Type: journals
Olanzapine-induced hyperglycaemic, hyperchloraemic, hyperosmolar state
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: Manjusha S Rathi, Michael W Mansfield Tags: Letters Source Type: journals
Community diabetes consultants: the case for additional training
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: Gillian Hawthorne, Waqar Malik, Felix Burden, Chris Walton, Jill Hill Tags: Letters Source Type: journals
Quality of diabetes care in India, China, Brazil, Mexico and Russia
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Employing US national standards, baseline data for type 2 diabetes were collected in India, China, Brazil, Mexico and Russia prior to Staged Diabetes Management implementation.In all, 5507 patients (India 2778, China 489, Brazil 1106, Mexico 925, and Russia 209) were evaluated. No site sample met the US standard for HbA1c or blood pressure. China, India and Mexico achieved criteria for LDL [ge] 130 mg/dL. Post-programme data from Russian sites showed significant improvement in HbA1c (p < 0.00001). In Brazil a trend toward improvement in blood pressure and blood glucose was also noted.Assessing current diabetes care employi...
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: ES Strock, RS Mazze Tags: Original Articles Source Type: journals
ABCD position statement on incretin mimetics and DPP-4 inhibitors -2009
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The Association of British Clinical Diabetologists (ABCD) currently recommends a limited place for exenatide and the gliptins in obese type 2 diabetes. Exenatide requires careful patient selection and continued specialist support, particularly to avoid initiation in individuals at risk of pancreatitis or for those who are already on insulin therapy. Hypoglycaemic and weight reduction efficacy may vary depending on baseline levels of HbA1c and body mass index. Continuation of therapy beyond six months should be determined by changes in weight and/or HbA1c. Gliptins should be reserved for less obese, less hyperglycaemic case...
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: CMB Edwards, PH Winocour, on behalf of the Association of British Clinical Diabetologists (ABCD) Tags: Position Statements Source Type: journals
News
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Tags: News Source Type: journals
The role of incretin-based therapies in the management of type 2 diabetes
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In patients with type 2 diabetes mellitus (T2DM), goals for blood glucose and other cardiovascular risk factors, such as blood pressure and body weight, can be difficult to achieve. Recent clinical trials indicate that incretin-based therapies - dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 (GLP-1) agonists - help to achieve glycaemic goals and are generally well tolerated, with a low prevalence of hypoglycaemia. GLP-1 agonists also improve weight, blood pressure and markers of [beta]-cell function. Addition of an incretin-based agent may be appropriate for selected patients with T2DM and unsatisfactory gly...
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: D Russell-Jones Tags: Reviews Source Type: journals
Treatment options for type 2 diabetes:introducing the incretin-based therapies
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In type 2 diabetes mellitus (T2DM), glycaemic control is often difficult to maintain and current treatments can produce adverse effects. The incretin-based therapies - dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 (GLP-1) agonists - improve glycaemic control when added to conventional therapies and are well tolerated, with a low incidence of hypoglycaemia. In addition, the GLP-1 agonists reduce body weight and systolic blood pressure and improve surrogates of [beta]-cell function. Incretin-based therapies may be appropriate for selected patients with T2DM when first-line therapy does not maintain glycaemic ...
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: AH Barnett Tags: Reviews Source Type: journals
The National Clinical Director for Diabetes: one year on
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - July 5, 2009 Category: Endocrinology Authors: Rowan Hillson Tags: Leaders Source Type: journals
Twenty-five years on [hellip]
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No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - June 30, 2009 Category: Endocrinology Authors: K Shaw Tags: Editorials Source Type: journals
