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29 records returned

Digestemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Lithium and cognition: meta-analysisBipolar disorder has been associated with cognitive impairment but it has been unclear what the contribution of medication may be. US investigators tackled the problem with a metaanalysis. They looked at 12 double-blind trials (from a possible 586 publications) in 539 healthy volunteers or patients (n=326) reporting the cognitive effects of lithium (J Clin Psychiatry 2009;doi:10.4088/ JCP.08r04972). Among patients, the mean duration of lithium use was 3.9 years and the mean serum concentration was 0.82mEq per litre. In volunteers, mean lithium exposure was 2.5 weeks and the mean serum le...
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Tags: Digest Source Type: journals

Adherence to risperidone long-acting injection dosing recommendationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The pharmacokinetic profile of risperidone long-acting injection (RLAI) has lead to specific recommendations for its treatment initiation. A team of Mental Health Nurse Advisers conducted this audit in a cohort of 1647 patients from 32 centres in the UK to assess to what extent treatment with RLAI is initiated according to these recommendations and how this affects treatment adherence. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: Brian Mangan, Clive Rogers, Kristina Wilton Tags: Audit Source Type: journals

Keynote Lecture: treating eating disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The Keynote Lecture at the eighth LatestAdvances in Psychiatry Symposium, held in London in March, was given by Professor Gerald Russell, Emeritus Professor of Psychiatry at the Institute of Psychiatry in London. He noted that eating disorders are sometimes associated with a markedly excess mortality. A high crude mortality rate (2.2 per cent per annum) was recorded in a UK series of compulsorily treated anorexia patients, in keeping with these patients, dogged resistance to treatment.1 While bulimia nervosa may respond to fluoxetine, there is no effective pharmacological treatment for anorexia nervosa. Nevertheless,psycho...
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: Mark Greener Tags: Keynote Lecture Source Type: journals

Management of migraine during pregnancyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr MacGregor discusses the effect of pregnancy on migraine and the treatment choices available to women during pregnancy and lactation. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: Anne MacGregor Tags: In Pregnancy Source Type: journals

Efficacy of iterative learning control for stroke rehabilitationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the April 2008 issue of Progress,we featured an article describing a new technique for improving arm movement following stroke developed at the University of Southampton.The technique involves the use of a robotic workstation delivering precisely controlled electrical stimulation mediated by iterative learning control to improve task performance.Here,the scientists who developed the system discuss the promising results of their pilot clinical study using this technique. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: Ann-Marie Hughes, Jane Burridge, Chris Freeman, Paul Chappell, Paul Lewin, Maggie Donovan-Hall, Bridget Dibb, Eric Rogers Tags: Research Updates Source Type: journals

Should neurologists wait and see or see and treat RRMS?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Early and aggressive treatment of rheumatoid arthritis (RA) is now regarded as best practice to limit irreversible joint damage. However, in the case of relapsing remitting multiple sclerosis (RRMS), current guidelines recommend that disease modifying therapy should only be initiated in patients with evidence of actively progressing disease. Here, the authors present the key findings of the Programme Identifying and Observing Novel Therapy Adoption in Chronic Diseases (PIONEER) study to examine the reasons for these different management approaches. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: David Bates, John Isaacs Tags: Original Research Source Type: journals

Dangers of diagnostic labels in patients with mental health issuesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Progress is pleased to bring readers key articles from the charity Primary Care Mental Health and Education (Primhe), which covers issues relating particularly to mental health in the primary care setting. On our website, , this month Dr Robinson, a GP with a special interest in mental health,describes how an encounter with a patient led her to re-evaluate her approach to patients with mental health issues. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 28, 2009 Category: Neurology Authors: A Robinson Tags: Primhe Source Type: journals

Mental health care - let's focus on the person, not the diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
When something does not work, we have a tendency to believe we just need to do more of the same, ie try harder. Mental health treatment is an example of this. When our patients fail to heed what we are saying, we often blame them for not listening, instead of asking why they are not compliant to our best intentions. The reality is that, for our patients and society in general, we lack credibility, as there is a general belief that treatments for mental health problems do not work. We reinforce this by maintaining people in secondary care services, rather than actively working to discharge them back into primary care servic...
Source: Progress in Neurology and Psychiatry - September 1, 2009 Category: Neurology Authors: Ian Walton Tags: Comments Source Type: journals

Digestemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Antidepressant RCTs meaningful?The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial of sequenced anti-depressant therapy recruited a broad population of patients representative of outpatients with depression seeking treatment. By contrast, most randomised controlled trials (RCTs) have more restrictive eligibility criteria. STAR*D investigators have now used their data to assess the impact of this aspect of trial design (Am J Psychiatry 2009;166:599-67).They divided 2855 STAR*D participants into a group meeting standard eligibility criteria based on HAM-D score >19, lack of comorbidity and duration of c...
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Tags: Digests Source Type: journals

Variations in anti-dementia drug prescribingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the context of a project to benchmark anti-dementia drug prescribing practice against standards derived from evidence-based guidelines, the authors sought to estimate the proportion of people with dementia who were receiving treatment with an anti-dementia drug and whether this varied across Primary Care Trust (PCT) populations.They also explored the relative proportion of prescriptions for each anti-dementia drug, and the source of these prescriptions - GPs,Mental HealthTrusts or acuteTrusts. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Authors: Sri Perecherla, Carol Paton, Amber Shingleton-Smith, Thomas RE Barnes Tags: Audit Source Type: journals

Treating generalised anxiety disorder: room to improveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In a Pfizer-sponsored satellite meeting at the Latest Advances in Psychiatry Symposium in London in March, Dr David Baldwin, Reader in Psychiatry and Honorary Consultant Psychiatrist at University of Southampton, reviewed the drug treatment of generalised anxiety disorder. Medical writer, Mark Greener, reports. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Authors: Mark Greener Tags: Satellite Meetings Source Type: journals

Readers pose their questions to Primary Care Mental Health and Educationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
No Abstract. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Tags: Ask Primhe Source Type: journals

Pharmacological treatments for ADHDemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the fourth of this series on the major psychiatric drug groups, Caroline Parker discusses the use of drug treatments in the management of attention deficit hyperactivity disorder (ADHD), including their indications, efficacy, adverse effects and recommended dosing regimens. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Authors: Caroline Parker Tags: Reviews Source Type: journals

Borderline personality disorder and sensory processing impairmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Sensory processing disorder (SPD) is a term advocated by some occupational therapists to describe a range of problems that might be amenable to particular treatment strategies, and has mainly been applied within the fields of paediatrics and learning disability.In this article,the authors investigate whether there could be a common ground between borderline personality disorder (BPD) and SPD and describe an extension of the treatment strategies for SPD to those with BPD in their acute inpatient unit. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - August 6, 2009 Category: Neurology Authors: Stephen Brown, Rohit Shankar, Kathryn Smith Tags: Original Research Source Type: journals

Time to reinvent the wheel in Primary Care Mental Healthemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
No Abstract. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - June 30, 2009 Category: Neurology Authors: Ian Walton Tags: Comments Source Type: journals

Digestemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Safety of ramelteonThere is great interest in the role of melatonin agonists as treatments for insomnia. Ramelteon is already available in the USA, where it is used to reduce sleep latency associated with primary insomnia. Licensing in Europe has been delayed after the European Medicines Agency questioned its efficacy. Two studies now report on the safety of ramelteon over one year.The first study enrolled 1213 adults taking ramelteon 16mg (18-64 year age group) or 8mg (over-65 years) and were considered compliant if they took it at least three nights per week (J Clin Psychiatry 2009; pii:ej07m03834). In the younger group ...
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Tags: Digest Source Type: journals

Mood stabilisers in the management of bipolar disorderemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
IIn the third of this series on the major psychiatric drug groups, the author discusses the choice and use of mood stabilisers in the management of bipolar affective disorder. Pharmacology, interactions and side-effects, as well as information to give to patients are described. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Authors: Michele Sie Tags: Reviews Source Type: journals

Agomelatine: a new approach to depressionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In a Servier-sponsored satellite meeting at the Latest Advances in Psychiatry Symposium in London in March, Professor Bill Deakin, Professor of Psychiatry and Director of the Neuroscience and Psychiatry Unit at the University of Manchester, reviewed a recent addition to the antidepressant armamentarium - agomelatine - a drug that that shows a unique pharmacological profile. Medical writer, Mark Greener, reports. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Authors: Mark Greener Tags: Satellite Meetings Source Type: journals

Parkinson's Disease Society research conferenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Progress: Advancing Parkinson's Research, the Parkinson's Disease Society research conference dedicated to showcasing the work of young Parkinson's disease researchers, was held in York in November 2008, attracting nearly 200 delegates. Neil Archibald, Parkinson's Disease Society Research Fellow, reports on some of the highlights of the conference, including stem cell and gene therapy research, the role of Lewy bodies in dementia and the use of deep brain stimulation in the treatment of Parkinson's disease. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Authors: Neil Archibald Tags: Conference Source Type: journals

Prevention and treatment of cluster headacheemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cluster headache is an excruciatingly painful primary headache syndrome with rapid onset attacks that are relatively short, typically up to three hours. Management strategies involve avoidance of possible triggers to attacks, such as alcohol and naps, and pharmacological treatments aimed at either quickly aborting acute attacks, or preventive therapies to suppress the attacks entirely, or reduce their frequency, severity or duration. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Authors: Anna S Cohen, Peter J Goadsby Tags: Reviews Source Type: journals

Does Parkinson's disease increase mortality?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Whether Parkinson's disease (PD) increases mortality remains something of a moot point. Some studies suggest that mortality among PD patients is more than three'fold higher than the death rates in the general population. Other studies suggest there's no difference. Changes in mortality over time are also inconsistent.However,some researchers detect a decline in mortality beginning during the 1970s,around the time that levodopa entered clinical practice.1 Now a new study2 that followed PD patients for 20 years helps clarify this sometimes controversial relationship. Freelance medical writer, Mark Greener, reports. Copyright...
Source: Progress in Neurology and Psychiatry - June 23, 2009 Category: Neurology Authors: Mark Greener Tags: News Reviews Source Type: journals

A clinical approach to managing somatoform disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Somatoform disorders, or medically unexplained symptoms, present a significant challenge to the clinician, who needs to establish and reassure the patient that the complaint is not serious, while at the same time try to avoid the symptoms being iatrogenically maintained. Here, Dr Hadler and Dr Poole suggest a practical approach to the management of such disorders. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 30, 2009 Category: Neurology Authors: Andrew Hadler, Norman A Poole Tags: Opinion Source Type: journals

Digestemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
'Real life' experience with rivastigmineThe Swedish Alzheimer Treatment Study is a non-blinded investigation of the long-term use of cholinesterase inhibitors for Alzheimer's disease in routine clinical practice (Acta Neurol Scand 2009;119:180-5). In a subgroup of 217 patients with mild to moderate disease (mean baseline Mini-Mental State Examination (MMSE) score 22.9, Alzheimer's Disease Assessment Scale - cognitive sub-scale (ADAS-cog) 18.5), treatment with rivastigmine was associated with an initial increase in MMSE score at two months, followed by a steady decline with a final difference of 1.84 points below baseline o...
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Tags: Digest Source Type: journals

Medicine taking behaviour in depression - part 2email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Medicine taking behaviour in depression is erratic, resulting in poor outcomes and increased cost to society.Indeed,the illness itself has been shown to be a risk factor for poor adherence.The first article of this two-part series (Progress issue 1, 2009) explored poor adherence with antidepressant treatment and effect on outcome. In this article treatment variables that may affect adherence are explored alongside some of the interventions that have been proposed to improve medicine taking behaviour in patients with depression.The effect these had on outcome is examined and recommendations, based on current evidence, are m...
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Authors: Celia Feetam Tags: Reviews Source Type: journals

Antipsychotics in the treatment of schizophreniaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the second of a new series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacists, the author discusses the use of antipsychotics through a review of the clinical literature. Pharmacology, interactions and side-effects as well as drug choice and information to give to patients are discussed. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Authors: Caroline Parker Tags: Reviews Source Type: journals

MND Associationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Few disorders are as devastating as motor neurone disease (MND). Imagine a healthy and alert mind trapped inside a body that cannot move: that's the reality of MND. Mel Barry, Communications Manager at the MND Association, discusses how the association is helping to support and improve the lives of people affected by the illness. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Tags: Patient Groups Source Type: journals

Use of atomoxetine in children and adolescents with ADHDemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Atomoxetine is a non-stimulant drug licensed for use in the treatment of attention deficit-hyperactivity disorder (ADHD).Dr Banerjee describes a study that was carried out over a two-year period in the three ADHD clinics in East Kent Hospitals NHS Trust to evaluate the current practice on the use of atomoxetine in ADHD in children and adolescents. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Authors: Somnath Banerjee Tags: Original Research Source Type: journals

Management of depression during pregnancyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr Osborne and Dr O'Keane discuss the risks discuss the risk factors for the development of depression during pregnancy, its possible impact on the developing foetus and the current recommended management. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 3, 2009 Category: Neurology Authors: Sarah Osborne, Veronica O'Keane Tags: In Pregnancy Source Type: journals

National dementia strategy could force rethink about resourcingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I welcome the Department of Health's National Dementia strategy.1 It rightly encourages early diagnosis in dementia and potetially the identification of a huge number of patients currently not recognised as having dementia. It should, by doing so, bring to attention the severe lack of resources for dementia patients and their carers and start to force the introduction of adequate services for a very needy and under-resourced group. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - March 1, 2009 Category: Neurology Authors: Ian Walton Tags: Comments Source Type: journals