Basic aspects in selecting a suitable transgenic rodent model for Alzheimer's disease.
Authors: Balmus IM, Ciobica A, Negura A, Negura L, Anton E
Abstract
Due to Alzheimer's disease (AD) great aggressiveness, many worldwide health associations began to globalize research efforts in order to find a suitable treatment and to clarify once and for all its controversial aetiology. Moreover, the animal modelling research is one of the best tools to evaluate molecular mechanisms and to correlate them with clinical features and behaviours. However, in order to provide valuable scientific data correlated to low error sources, a rigorous algorithm of selecting the proper animal model for testing is re...
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Altered pain perception in self-injurious behavior and the association of psychological elements with pain perception measures: a systematic review.
CONCLUSIONS: Pain perception was altered in participants with NSSI. Pain perception was associated to emotional dysregulation, self-criticism, neuroticism and painful and provocative experiences. Because of the small number of studies reviewed, results should be seen as guidelines for further studies. They should be replicated on a bigger sample of studies. Further research should focus on pain perception measures in participants with NSSI and an excluded personality disorder.
PMID: 26609646 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Evidence-based Neuro Linguistic Psychotherapy: a meta-analysis.
CONCLUSION: Neuro-Linguistic Psychotherapy as a psychotherapeutic modality grounded in theoretical frameworks, methodologies and interventions scientifically developed, including models developed by NLP, shows results that can hold its ground in comparison with other psychotherapeutic methods.
PMID: 26609647 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Treatment effectiveness in patients with schizophrenia as measured by the ASSESS battery - first longitudinal data.
CONCLUSIONS: This pilot study revealed that ASSESS is easy to apply in clinical practice and is a suitable tool for psychiatrists since it covers all the relevant aspects of the course of schizophrenia in a compact form.
PMID: 26609648 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Exploring the association between the Iowa Gambling Task and community functioning in people with schizophrenia.
CONCLUSIONS: DM impairment may represent an important contributor to poor functional outcomes in people with schizophrenia. Interventions targeting decision making and higher order cognitive problems in people with schizophrenia may have a greater impact on functional difficulties.
PMID: 26609649 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Metabolic syndrome in schizophrenia - who is more to blame: FGA polypharmacy or clozapine monotherapy?
CONCLUSION: Compared to polypharmacy with first generation antipsychotics, the higher prevalence of metabolic syndrome is found in patients treated with Clozapine alone. The most prevalent metabolic disorder is dyslipidemia.
PMID: 26609650 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
COX-2 gene variants in bipolar disorder-I.
CONCLUSIONS: It seems that there is a protective role of COX-2-1195A→G G+ genotype against BD-I (p:0.000). In addition, there was a weak linkage disequilibrium between COX-2-765G→C and COX-2-1195A→G polymorphisms. Our findings suggest that COX-2-1195A→G AA genotype may faciliate the development of BD-I.
PMID: 26609651 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Temperament and character traits in patients with conversion disorder and their relations with dissociation.
CONCLUSIONS: Low NS temperament traits may be associated with conversion disorder. High HA and low RD temperament traits and low SD and high ST character traits may be associated with pathological dissociation in patients with conversion disorder.
PMID: 26609652 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Symptom Dimensions, Smoking and Impulsiveness in Obsessive-Compulsive Disorder.
CONCLUSIONS: OCD is a heterogeneous disorder in terms of smoking. Impulsiveness, which does not significantly vary across distinct symptom dimensions, cannot explain this heterogeneity. The severity of addiction does not differ in smokers with OCD across symptom dimensions.
PMID: 26609653 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Fatigue during multiple sclerosis relapse and its relationship to depression and neurological disability.
CONCLUSION: Fatigue is a frequent symptom during multiple sclerosis relapse. Depression and, to a lesser degree, disability but not relapse severity are independently related to the presence of fatigue. Depression and fatigue should be recognized and treated during standard relapse treatment. Further research might focus on other factors influencing fatigue during multiple sclerosis relapse including evaluation of fatigue at the different time points.
PMID: 26609654 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Effects of exercise dependence on psychological health of Chinese college students.
CONCLUSIONS: Exercise dependence adversely affects the psychological health of college students. Further research using multi-dimensional exercise addiction scales should be conducted to identify all the negative effects of exercise addiction factors on psychological health.
PMID: 26609655 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Could alexithymia predict suicide attempts - a study of Croatian war veterans with post-traumatic stress disorder.
CONCLUSIONS: These results point out that alexithymia can be considered as a potential risk factor for suicide in this population, suggesting that it may also be used as an indicator of worsening psychological status and attempted suicide in other population groups with higher alexithymia prevalence.
PMID: 26609656 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Severe acute pancreatitis, neuroleptic malignant syndrome and grand mal seizures associated with elevated amisulpride and low clozapine serum levels.
Authors: Bonnet U, Taazimi B, Montag M, Ronge R, Gespers H, Kuhlmann R, Grabbe D, Jahn J
PMID: 26609657 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Late diagnosis of Asperger syndrome in Croatia - a low-income country.
Authors: Petković ZB, Maršanić VB, Divčić B, Ercegović N
PMID: 26609658 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
Koro, Othello and Capgras syndromes in one patient with drug induced psychosis.
Authors: Gama Marques J
PMID: 26609659 [PubMed - as supplied by publisher] (Source: Psychiatria Danubina)
Source: Psychiatria Danubina - November 27, 2015 Category: Psychiatry Tags: Psychiatr Danub Source Type: research
