Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform
Lab Chip, 2024, Advance Article DOI: 10.1039/D4LC00016A, PaperEthan J. Lockhart, Lisa F. Horowitz, Ad án Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert Folch A microfluidic platform was developed that hydrodynamically traps microdissected cuboids for selective drug treatments and isolates conditions with thermoplastic valves. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 23, 2024 Category: Chemistry Authors: Ethan J. Lockhart Source Type: research

Correction: Direct laser writing-enabled 3D printing strategies for microfluidic applications
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. Sochol To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 22, 2024 Category: Chemistry Authors: Olivia M. Young Source Type: research

Automated Dynamic Inlet Microfluidics System: 3D Printer Adaptation for Cost-Effective, Low Volume, On-Demand Multi-Analyte Droplet Generator
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00075G, PaperAbdul Basit Zia, Justin Farrell, Ian G. Foulds The paper demonstrates an adaptation of a 3D printer (Prusa Mini+) with novel modules to develop a droplet generation system that generates combinatorial droplets from a standard 96 well plate.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 22, 2024 Category: Chemistry Authors: Abdul Basit Zia Source Type: research

Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00149D, PaperSunil Shrestha, Vinod Kumar Reddy Lekkala, Prabha Acharya, Soo-Yeon Kang, Manav Goud Vanga, Moo-Yeal Lee Human liver organoids (HLOs) hold significant potential for recapitulating the architecture and function of liver tissues in vivo. However, conventional culture methos of HLOs, forming Matrigel domes in 6-/24-well plates,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 20, 2024 Category: Chemistry Authors: Sunil Shrestha Source Type: research

High-resolution low-cost LCD 3D printing for microfluidic and organ-on-a-chip devices
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Houda Shafique, Vahid Karamzadeh, Geunyong Kim, Molly L. Shen, Yonatan Morocz, Ahmad Sohrabi Kashani, David Juncker The fabrication of microfluidic devices has progressed from cleanroom manufacturing to replica molding in polymers, and more recently to direct manufacturing by subtractive (e.g., laser machining) and additive (e.g., 3D... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 19, 2024 Category: Chemistry Authors: Houda Shafique Source Type: research

Microflow sensing and control using an in-channel birefringent biomembrane
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Nan Jia, Tianyang Deng, Charles Larouche, Tigran Galstian, Andr é Bégin-Drolet, Jesse Greener We report a flow sensitive birefringent in-channel chitosan micromembrane. Using a simple cross-polarizer and a calibration curve, the membrane functions as a flow rate meter, which also works as a feedback element for a flow control system. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 19, 2024 Category: Chemistry Authors: Nan Jia Source Type: research

Advanced sequencing-based high-throughput and long-read single-cell transcriptome analysis
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00105B, Critical ReviewShanqing Huang, Weixiong Shi, Shiyu Li, Qian Fan, Chaoyong Yang, Jiao Cao, Lingling Wu Cells are the fundamental building blocks of living systems, exhibiting significant heterogeneity. The transcriptome connects the cellular genotype and phenotype, and profiling single-cell transcriptome is critical for uncovering distinct cell... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 19, 2024 Category: Chemistry Authors: Shanqing Huang Source Type: research

A microfluidic microalgae detection system for cellular physiological response based on object detection algorithm
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC00941F, PaperShizheng Zhou, Tianhui Chen, Edgar S. Fu, Liuyong Shi, Teng Zhou, Hong YAN The composition of species and the physiological status of microalgal cells serve as significant indicators for monitoring marine environments. Symbiotic with corals, Symbiodiniacea are more sensitive to the environmental response.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 18, 2024 Category: Chemistry Authors: Shizheng Zhou Source Type: research

Development of a microfluidic device to enrich and detect zearalenone in food using quantum dot-embedded molecularly imprinted polymers
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00193A, PaperMarti Hua, Shenmiao Li, Roopesh Syamaladevi, Xiaonan Lu Mycotoxins are secondary metabolites of certain moulds, prevalent in 60-80% of food crops and many processed products but challenging to eliminate. Consuming mycotoxin-contaminated food and feed can lead to various... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 17, 2024 Category: Chemistry Authors: Marti Hua Source Type: research

Investigation of air bubble behaviour after gas embolism events induced in a microfluidic network mimicking microvasculature
This study conductedin vitro experimentation using microvascular tissue-like structures to examine the dynamics of interfacial forces leading to gas bubble cessation, with the objective of providing a medical guideline for preventing gas embolism. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 16, 2024 Category: Chemistry Authors: Mohammad Mahdi Mardanpour Source Type: research

Study on the hemodynamic effects of different pulsatile working modes of a rotary blood pump using a microfluidic platform that realizes in vitro cell culture effectively
Lab Chip, 2024, Advance Article DOI: 10.1039/D4LC00159A, PaperLixue Liang, Xueying Wang, Dong Chen, Palaniappan Sethu, Guruprasad A. Giridharan, Yanxia Wang, Yu Wang, Kai-Rong Qin The best pulsation frequency mode of the RBP would be one that changes every 2 –3 times of the cardiac cycle. The proposedin vitro microfluidic model could provide an effective platform to select the best working mode of the RBP for heart failure. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 16, 2024 Category: Chemistry Authors: Lixue Liang Source Type: research

Multiplex nanozymatic biosensing of Salmonella on a finger-actuated microfluidic chip
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00291A, PaperNana Jin, Fan Jiang, Fengzhen Yang, Ying Ding, Ming Liao, Yanbin Li, Jianhan Lin A colorimetric biosensor was elaboratively designed for fast, sensitive and multiplex bacterial detection on a single microfluidic chip using immune magnetic nanobeads for specific bacterial separation, immune gold@platinum palladium nanoparticles... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 16, 2024 Category: Chemistry Authors: Nana Jin Source Type: research

Dielectrophoretic characterization and selection of non-spherical flagellate algae in parallel channels with right-angle bipolar electrodes
Lab Chip, 2024, Advance Article DOI: 10.1039/D4LC00165F, PaperXiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu, Zhipeng Song, Yong Zhao We develop a microfluidic device with closed right-angle bipolar electrodes to realize dielectrophoretic characterization and selection of non-spherical flagellate algae. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 15, 2024 Category: Chemistry Authors: Xiaoming Chen Source Type: research

Portable platform for leukocyte extraction from blood using sheath-free microfluidic DLD
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00132J, PaperOriana Gerallin Chavez-Pineda, Roberto Rodriguez-Moncayo, Alan Mauricio Gonzalez-Suarez, Pablo Enrique Guevara-Pantoja, Jose Luis Maravillas-Montero, Jose L. Garcia-Cordero Leukocyte count is routinely performed for diagnostic purposes and is rapidly emerging as a significant biomarker for a wide array of diseases. Additionally, leukocytes have demonstrated considerable promise in novel... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 15, 2024 Category: Chemistry Authors: Oriana Gerallin Chavez-Pineda Source Type: research

Rocking- and diffusion-based culture of tumor spheroids-on-a-chip
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC01116J, PaperDuomei Tian, Zheng Mao, Li Wang, Xiaochen Huang, Wei Wang, Haoyue Luo, Juan Peng, Yong Chen Tumor spheroids are now intensively investigated toward preclinical and clinical applications, necessitating the establishment of accessible and cost-effective methods for routine operations. Without losing the advantage of organ-chip technologies, we... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 15, 2024 Category: Chemistry Authors: Duomei Tian Source Type: research