An Overview of Recent Patents and Patented Technology Platforms based on Co-processed Excipients.
CONCLUSION: In this work, the authors have focussed on recent patents and commercial technologies on co-processed excipient. A better understanding of this will help researchers and pharmaceutical industries to select the appropriate platform, or to develop new innovative co-processed excipients with improved tableting characteristics. PMID: 33397276 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - January 7, 2021 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Techniques of Mucilage and Gum Modification and their Effect on Hydrophilicity and Drug Release.
CONCLUSION: The present manuscript highlight the advantages, modifications of gum and mucilage, their effects on hydrophilicity and drug release as well as aspects of the natural gums which can be assumed to be bifunctional excipient because of their concentration-dependent effect on drug release and their high degree of swellability. PMID: 33280600 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - December 9, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Oral Disintegrating Tablets - An Updated Patent Perspective.
Authors: Sharma S, Singh K Abstract Current development in drug delivery system has been employed with an endeavour of enhancing the bioavailability, mask the taste of drug, rapid onset of action and improve patient compliance. An alternative approach of conventional dosage form is being employed to triumph over all these issues named as Orodispersible system. Over past three decades this novel dosage form gain a considerable attention as compared to other conventional solid dosage form such as tablet and capsules. ODTs dissolved or disintegrate within few seconds to a minute when put on the tongue, withou...
Source: Recent Patents on Drug Delivery and Formulation - November 26, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Increasing Progenitor Cell Proliferation in the Sub-Ventricular Zone: A Therapeutic Treatment for Progressive Multiple Sclerosis?
CONCLUSION: There are innate gender differences in progenitor cell proliferation at the Sub-Ventricular Zone at middle age in rats, possibly due to loss of estrogen in females. We also see notable gender differences in progenitor cell proliferation in the Sub ventricular Zone in the response to common drugs, such as fluoxetine, simvastatin and Vitamin C (ascorbic acid). PMID: 33208084 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - November 20, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Preface.
Authors: Giovagnoli S PMID: 33054700 [PubMed - in process] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - October 20, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Progresses and Challenges of Fast Dissolving/Disintegrating Dosage Forms in Manufacturing, Formulation Screening, Preclinical Testing and Drug Delivery.
Authors: Saharan VA PMID: 33054701 [PubMed - in process] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - October 20, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Study and Development of an Anthroposophical Formula Based on Phosphorus and Formica rufa for Onychomycosis ´s Treatment.
Study and Development of an Anthroposophical Formula Based on Phosphorus and Formica rufa for Onychomycosis´s Treatment. Recent Pat Drug Deliv Formul. 2020 Sep 17;: Authors: Rodrigues AM, de Figueiredo SM, La Santrer EFR, Assunção CB, de Abreu ASG, Johann S, Caligiorne RB Abstract Onychomycosis is a fungal infection of the nail plate or nail bed that leads to gradual destruction of the nail. The main difficulties in the treatment of onychomycosis refer to the duration of treatments and their side effects. Thus, it becomes relevant to look for new therapeutic alternatives in the...
Source: Recent Patents on Drug Delivery and Formulation - September 20, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

A Review on Recent Technologies and Patents on Silica Nanoparticles for Cancer Treatment and Diagnosis.
CONCLUSION: An ideal nano-carrier must have high loading efficiency, easily detectable, and must have stimuli's sensitive, site-specific drug release. The patent study explores new dimensions on MSNs synthesis by claiming new cost-effective templates and silica source, a more safe environment for synthesis, reducing synthesis steps, duration of reaction, effective loading of low solubility drugs by magnetized nanocarriers, pathogen-specific release and development of novel photoluminescent rechargeable MSNs under mild conditions. It's a challenging task for researchers to successfully translate their prototypes to industri...
Source: Recent Patents on Drug Delivery and Formulation - September 17, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Patent Perspective on Orodispersible Films.
Authors: Gupta S, Kumar TP, Gowda DV Abstract The traditional oral dosage forms (tablets, capsules, syrups, and elixirs) suffer from various disadvantages. They are pretty challenging to administer to patients with dysphagia, mucositis, and vomiting tendency. Therefore, gaining patient compliance using conventional dosage forms is highly cumbersome. One of the most transformative and innovative approaches to overcome such challenges is Orodispersible Films, a Novel Drug Delivery System. They are easy to consume, no need to chew or swallow and they don't even require water for consumption. Therefore, severa...
Source: Recent Patents on Drug Delivery and Formulation - September 6, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Surface modified polymeric nanoparticles for drug delivery: preparation and applications.
Authors: Joshi G, Sawant K, Patel M, Chaudhary D Abstract Nanotechnology is one of the emerging fields in the drug delivery for targeting the drug to the site of action. The polymeric nanoparticles as drug delivery systems have gained importance for the last few decades. They offer advantages over liposomes, dendrimers, emulsions etc. Surface engineering of polymeric nanoparticles is widely utilized to effectively target the cells in various diseases such as cancer, HIV infection. Surface modified nanoparticles offer various advantages such as targeted drug delivery, reduction in side effects, dose reducti...
Source: Recent Patents on Drug Delivery and Formulation - September 6, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Formulation Development and Evaluation of Herbal Effervescent Mouthwash Tablet containing Azadirachta Indica (Neem) and Curcumin for the Maintenance of Oral Hygiene.
CONCLUSION: The developed herbal formulation (F3) has a good potential to maintain oral hygiene as compared to alcoholic mouthwash and further studies may be necessary to confirm the efficacy of the formulation since a single bacterial strain was assayed. PMID: 32819253 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - August 22, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Recent Approaches on Novel Topical Delivery Systems for Atopic Dermatitis Treatment.
Authors: Kahraman E, Aydilek N, Güngör S Abstract Atopic dermatitis is a chronic inflammatory disease of the skin, which is characterized by itching, erythema and eczematous lacerations. It affects about 10 % of adults and approximately 15-20 % of children in the worldwide. As a result of genetic, immunologic and environmental factors, the disease manifests itself with impaired stratum corneum barrier and then immunological responses. Topical administration of corticosteroids and calcineurin inhibitors are currently used as the first strategy in the management of disease. However, they have low skin bioa...
Source: Recent Patents on Drug Delivery and Formulation - August 22, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Novel Nanolipoidal Systems for the Management of Skin Cancer.
Authors: Singh A, Srivastava N Abstract Skin cancer, among the various kinds of cancer, is a type that emerges from skin due to the incident growth of abnormal cells. These cells are capable of spreading and invading the other parts of body. The occurrence of non-melanoma and melanoma, which are the major types of skin cancer, has increased over the past decades. Exposure to ul-traviolet radiations (UV) is the main associative cause of skin cancer. UV exposure can inactivate tumor suppressor genes while activating various oncogenes. The conventional techniques like surgical removal, chemotherapy and radiat...
Source: Recent Patents on Drug Delivery and Formulation - August 19, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Development, Characterization and Pharmacological Evaluation of Anti-blemish Cream Containing Herbal Oils.
CONCLUSION: Thus, it was concluded that the developed antiblemish cream containing herbal oils possess significant antiblemish potential. This study necessitates further evaluations in human subjects as it could have highly positive therapeutic value in the treatment of hyperpigmentation. PMID: 32479252 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - June 2, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Pharmaceutical Manipulations for Ocular Drug Delivery.
Authors: Tiwary AK PMID: 32400325 [PubMed - in process] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - May 16, 2020 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research