Influence of manipulative skills on quality of life and activities of daily living in multiple sclerosis
CONCLUSIONS: The findings of this study point to the fact that patients diagnosed with multiple sclerosis have a decrease in prey strength, pinch strength, manipulative dexterity, quality of life and autonomy in activities of daily living compared to the healthy population.PMID:38618668 | DOI:10.33588/rn.7808.2023297 (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: S Rodr íguez-Menéndez R M Mart ínez-Piédrola M Men éndez-González M P érez-de-Heredia-Torres Source Type: research

Effects on cognitive processes of dual-task training in people with Parkinson's disease: a systematic review
CONCLUSIONS: Increased research and standardized intervention programmes are essential. Longitudinal and randomized controlled studies in representative samples which provide conclusions that are applicable to other contexts are also important.PMID:38618669 | DOI:10.33588/rn.7808.2024049 (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: M J Dur án-Navarrete M J Soto-Voitmann G Torres-Araneda L D Lagos-Guti érrez Source Type: research

Guide for the treatment of acute altered mental status. Iberoamerican Academy of Pediatric Neurology
Rev Neurol. 2024 Apr 16;78(8):229-235. doi: 10.33588/rn.7808.2023302.ABSTRACTIn pediatric patients, an acute altered mental status refers to a sudden and significant change in a child's brain function and level of consciousness. It may manifest as confusion, disorientation, agitation, lethargy or even a loss of consciousness. This condition is a medical emergency, and requires immediate evaluation and attention. There are several causes of acute altered mental status in children, including infections of the central nervous system such as meningitis or encephalitis, traumatic brain injury, metabolic disorders, seizures and ...
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: D L ópez F Espinel E Andrade A S Aguirre Source Type: research

The importance of adherence to treatment in control of epilepsy
Rev Neurol. 2024 Apr 16;78(8):237. doi: 10.33588/rn.7808.2024079.ABSTRACTTITLE: Relevancia de la adhesión al tratamiento en el control de la epilepsia.PMID:38618671 | DOI:10.33588/rn.7808.2024079 (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: J J Poza-Aldea Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research