White dreams are made of colours: What studying contentless dreams can teach about the neural basis of dreaming and conscious experiences
Reports of white dreams, the feeling of having had a dream experience without being able to specify this experience any further, make up almost one third of all dream reports, yet this phenomenon —until very recently—had not yet been in the focus of targeted investigations. White dreams are typically interpreted as forgotten dreams, and are sidelined as not being particularly informative with regard to the nature of dreaming. In this review article, we propose a paradigm shift with respe ct to the status of white dreams arguing that focusing on this phenomenon can reveal fundamental insights about the neural processes ...
Source: Sleep Medicine Reviews - November 13, 2018 Category: Sleep Medicine Authors: Peter Fazekas, Georgina Nemeth, Morten Overgaard Tags: Theoretical Review Source Type: research

What are the determinants of children ’s sleep behavior? A systematic review of longitudinal studies
To develop evidence-based healthy sleep interventions for children, this review provides insight into the behavioral determinants of sleep behavior. Hence the objective of this review is to systematically review the longitudinal evidence on determinants of children ’s sleep behavior.Studies were identified from searches in PubMed, PsycINFO, and Web of Science, until January 2017. Longitudinal studies investigating the association between potential determinants and sleep behavior (duration, quality and timing) in healthy children aged 4-12 years were included . (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 12, 2018 Category: Sleep Medicine Authors: Laura S. Belmon, Maartje M. van Stralen, Vincent Busch, Irene A. Hamsen, Mai J.M. Chinapaw Tags: Clinical Review Source Type: research

Local Sleep
The historic sleep regulatory paradigm invokes “top-down” imposition of sleep on the brain by sleep regulatory circuits. While remaining conceptually useful, many sleep phenomena are difficult to explain using that paradigm, including, unilateral sleep, sleep-walking, and poor performance after sleep deprivation. Further, all animals sleep a fter non-lethal brain lesions, regardless of whether the lesion includes sleep regulatory circuits, suggesting that sleep is a fundamental property of small viable neuronal/glial networks. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 12, 2018 Category: Sleep Medicine Authors: James M. Krueger, Joseph T. Nguyen, Cheryl J. Dykstra-Aiello, Ping Taishi Tags: Theoretical Review Source Type: research

Insomnia and mortality: a meta-analysis
The purpose of this review was to evaluate the strength of evidence for a relationship between risk of mortality and frequent and ongoing insomnia using a meta-analytic strategy.Seventeen studies, including a total of 36,938,981 individuals followed up for a mean of 11.6 years, reporting the investigation of the association between mortality and frequent ( ≥3 nights/week), ongoing (≥1 month) insomnia were identified.There was no difference in the odds of mortality for those individuals with symptoms of insomnia when compared to those without symptoms (OR= 1.06, 95%CI=0.61-1.84, p=.84). (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 11, 2018 Category: Sleep Medicine Authors: Nicole Lovato, Leon Lack Tags: Clinical Review Source Type: research

The neurophysiological and neurochemical effects of alcohol on the brain are inconsistent with current evidence based models of sleepwalking
The DSM-5 and ICSD-3 have removed alcohol from the list of potential triggers for sleepwalking due to the lack of empirical evidence. Recent imaging and EEG based studies of sleepwalking and confusional arousals have provided a more data-based method of examining if alcohol is compatible with what is known about the neurophysiology and neurochemistry of sleepwalking. These studies have demonstrated a deactivation of the frontal areas of the brain, while the cingulate or motor cortex remains active and characterized activation in the form of beta EEG. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 10, 2018 Category: Sleep Medicine Authors: Mark R. Pressman Tags: Clinical Review Source Type: research

The Importance of Sleep for Governmental Sectors, General Population and Industry – Asia-Pacific Economic Cooperation (APEC) Sleep Technology Agenda
Sleep is a field of study that encompasses several areas relevant to many of every country ’s governmental sectors, as well as industry and general population. The focus of this Letter will be to address how researching sleep can reduce health expenses, increase national productivity, bring awareness to public safety and facilitate health and medical related industry development based o n the Sleep Technology Agenda (STA) [1] presented at the Asia-Pacific Economic Cooperation (APEC) meeting in Ho-Chi-Ming City, Vietnam, August 2017. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 9, 2018 Category: Sleep Medicine Authors: Rayleigh Ping-Ying Chiang, Chien-Fu Lin, Yu-Chuan (Jack) Li, Min-Huei Hsu Tags: Letter to the editor Source Type: research

Neurobiological and Immunogenetic Aspects of Narcolepsy: Implications for Pharmacotherapy
Excessive daytime sleepiness (EDS) and cataplexy are common symptoms of narcolepsy, a sleep disorder associated with the loss of hypocretin/orexin (Hcrt) neurons. Although only a few drugs have received regulatory approval for narcolepsy to date, treatment involves diverse medications that affect multiple biochemical targets and neural circuits. Clinical trials have demonstrated efficacy for the following classes of drugs as narcolepsy treatments: alerting medications (amphetamine, methylphenidate, modafinil/armodafinil, solriamfetol [JZP-110]), antidepressants (tricyclic antidepressants, selective serotonin reuptake inhib...
Source: Sleep Medicine Reviews - November 8, 2018 Category: Sleep Medicine Authors: Steven T. Szabo, Michael J. Thorpy, Geert Mayer, John H. Peever, Thomas S. Kilduff Tags: Physiological Review Source Type: research

The risk of neurodegeneration in REM Sleep Behavior Disorder: A systematic review and meta-analysis of longitudinal studies
Several studies report an association between REM Sleep Behavior Disorder (RBD) and neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD precedes the development of neurodegeneration by several years. This review and meta-analysis aims to establish the rate of conversion of RBD into neurodegenerative diseases. Longitudinal studies were searched from the PubMed, Web of Science, and SCOPUS databases. Using random-effect modeling, we performed a meta-analysis on the rate of RBD conversions into neurodegeneration. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 8, 2018 Category: Sleep Medicine Authors: Andrea Galbiati, Laura Verga, Enrico Giora, Marco Zucconi, Luigi Ferini-Strambi Tags: Clinical Review Source Type: research

What works for jetlag? A systematic review of non-pharmacological interventions
Jetlag is a combination of travel fatigue and circadian misalignment resulting from air travel across time zones. Routinely recommended interventions based on circadian science include timely exposure to light and darkness (scheduled sleep), but the real-world effectiveness of these and other non-circadian strategies is unknown. We systematically reviewed the evidence for non-pharmacological interventions for jetlag. PubMed, EMBASE, Scopus, and Web of Science were searched. Studies reviewed (i) involved human participants undergoing air travel with a corresponding shift in the external light-dark cycle; (ii) administered a...
Source: Sleep Medicine Reviews - November 7, 2018 Category: Sleep Medicine Authors: Yu Sun Bin, Svetlana Postnova, Peter A. Cistulli Tags: Clinical Review Source Type: research

The Effect of Non-Pharmacological Sleep Interventions on Depression Symptoms: A Meta-Analysis of Randomised Controlled Trials
Poor sleep is a significant risk factor for depression across the lifespan and sleep problems have been hypothesised to contribute to the onset and maintenance of depression symptoms. However, sleep problems are usually not a direct target of interventions for depression. A range of non-pharmacological treatments can reduce sleep problems but it is unclear whether these interventions also reduce other depression symptoms. The aim of this review was to examine whether non-pharmacological interventions for sleep problems are effective in reducing symptoms of depression. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 5, 2018 Category: Sleep Medicine Authors: Brioney Gee, Faith Orchard, Emmet Clarke, Ansu Joy, Tim Clarke, Shirley Reynolds Tags: Clinical Review Source Type: research

Comments on: "Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis ”
We read an article written by Shi et al. (1) with interest. The authors performed a systematic review and meta-analysis of 18 longitudinal studies to determine whether sleep disturbances (including insomnia, sleep disordered breathing, and other sleep problems) increase the risk of dementia. The meta-analysis was done by computing overall relative risk (RR) of incident dementia. The main findings from this study showed that sleep disturbances might increase risk of all-cause dementia, Alzheimer's disease, and vascular dementia. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 5, 2018 Category: Sleep Medicine Authors: Anawin Sanguankeo, Sikarin Upala Tags: Letter to the editor Source Type: research

Editorial Board
(Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 4, 2018 Category: Sleep Medicine Source Type: research

Reply to Sanguankeo and Upala on “Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis
Recently the putative role of sleep problems in the incidence and development of dementia attracted considerable attention [1]. We previously reported on this relationship in a systematic review and meta-analysis [2]. In a commentary on our work, Drs. Sanguankeo and Upala proposed two points that might strengthen our meta-analysis [3]. We thank them for these suggestions and appreciate their efforts in improving the quality of our work. However, we should point out that in our meta-analysis, we had already taken the comments they offered into consideration. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 3, 2018 Category: Sleep Medicine Authors: Le Shi, Yan-Ping Bao, Si-Jing Chen, Meng-Ying Ma, Ying Han, Yu-Mei Wang, Jie Shi, Michael V. Vitiello, Lin Lu Tags: Letter to the editor Source Type: research

The Psychological Wellbeing Outcomes of Nonpharmacological Interventions for Older Persons with Insomnia Symptoms: A Systematic Review and Meta-Analysis
Nonpharmacological treatment of insomnia in older persons has been associated with reduced insomnia symptoms and increased psychological wellbeing. This systematic review and meta-analysis examined whether nonpharmacological interventions can promote wellbeing indicators in older persons who experience insomnia symptoms and investigated the components of these interventions. Twenty studies met inclusion criteria. Psychological wellbeing outcomes included symptoms of depression, anxiety, mental health-related quality of life, and fatigue. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 27, 2018 Category: Sleep Medicine Authors: Rotem Perach, Courtney K. Allen, Ioanna Kapantai, Juan J. Madrid-Valero, Eleanor Miles, Rebecca A. Charlton, Alice M. Gregory Tags: Clinical Review Source Type: research

Sleep and the human impacts of climate change
In this issue of Sleep Medicine Reviews, Rifkin and colleagues (referred subsequently as RLP) [1] report on a systematic review of the literature – and present a conceptual framework for – the potential impacts of climate change on human sleep. Their review spans literature from 1980-2017 and results in 16 studies matching the authors’ selection criteria. Across these studies, RLP report a tendency of exposure to warmer temperatures, ex treme weather events, floods, or wildfires to associate with diminished total sleep times as well as incidences of sleep disruption. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 24, 2018 Category: Sleep Medicine Authors: Nick Obradovich, Robyn Migliorini Tags: Guest editorial Source Type: research