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Role of PPARα in control of torpor through FGF21–NPY pathway: From circadian clock genes to seasonal change and cardiovascular diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In nature, hibernating animals experience fasting, cold temperature, and short day seasonally. Torpor is a state of decreased physiological activity in an animal, usually characterized by a reduced body temperature and rate of metabolism to adapt to such a severe environment. Ablation of the central clock synchronizer, the suprachiasmatic nucleus in brain, abolishes torpor, a hibernation-like state, implicating the circadian clock involved in this seasonal change. Biologists know well that the energy source of daily heterotherms/hibernators change from glucose to lipids in winter. Here we review several lines of evidence o...
Source: Sleep and Biological Rhythms - November 4, 2009 Category: Neurology Authors: Norio K ISHIDA, Daisuke UCHIDA, Ryosuke DOI, Katsutaka OISHI, Sachiko CHIKAHISA, Hiroyoshi SEI, Yasutaka HAMASAKA, Takahiro SUZUKI, Shuji HANAI Source Type: journals

Restricted feeding-induced entrainment of activity rhythm and peripheral clock rhythmEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Daily restricted feeding entrains the circadian rhythm of mouse clock gene expression in the central nervous system excluding the suprachiasmatic nucleus, as well as in the peripheral tissues such as the liver, lungs, and heart. In addition to entrainment of the clock gene, daily restricted feeding induces a locomotor activity increase 2[ndash]3 h before the restricted feeding time. The increase of activity is called the food anticipatory activity (FAA). At present, the mechanisms for restricted feeding-induced entrainment are still unknown. In this review, we describe the role of the central nervous system and peripheral ...
Source: Sleep and Biological Rhythms - November 4, 2009 Category: Neurology Authors: Shigenobu SHIBATA, Akiko HIRAO, Yu TAHARA Source Type: journals

Impact of age on human non-visual responses to lightEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ageing is associated with increased disturbances in the timing, duration, and quality of sleep. These disruptions may reflect changes in the circadian timing system and/or the sleep homeostat which are both necessary to produce consolidated sleep at an appropriate time. In addition, it is possible that age-related alterations in the detection and transmission of the photic signal responsible for synchronizing the circadian clock may play a role. Ageing is accompanied by many changes within the eye including alterations in pupil size, lens transmission, and number of photoreceptors. The observed increase in ocular lens dens...
Source: Sleep and Biological Rhythms - November 4, 2009 Category: Neurology Authors: Victoria L REVELL, Debra J SKENE Source Type: journals

Molecular mechanisms of circadian timekeeping in DrosophilaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Molecular and genetic studies in the fruit fly Drosophila melanogaster have revealed that the circadian timekeeping mechanism is based on feedback loops in gene expression. These feedback loops, which are highly conserved in mammals, can be divided into temporally distinct transcriptional activation, repression, and reactivation phases. Determining how different phases of the transcriptional feedback cycle are controlled and integrated is necessary to understand the molecular basis of circadian timekeeping. In Drosophila, feedback loop function is initiated when hypophosphorylated CLOCK (CLK) forms a heterodimer with CYCLE...
Source: Sleep and Biological Rhythms - September 30, 2009 Category: Neurology Authors: Paul E HARDIN Source Type: journals

CIPC-dependent phosphorylation of CLOCK and NPAS2 in circadian clockworkEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Circadian rhythms are generated by the cell-autonomous circadian clock, in which the clock genes form a transcription/translation-based negative feedback loop. Basic helix-loop-helix (bHLH)-PAS (Period-Arylhydrocarbon receptor nuclear translocator-Single minded) transcription factors, CLOCK and BMAL1, form a complex and bind to E-box elements for activation of the transcription, which is suppressed by circadian binding with a variety of negative regulators. We found that CLOCK protein is mostly kept in the phosphorylated form over the day and is hyperphosphorylated in the suppression phase of E-box-dependent transcription....
Source: Sleep and Biological Rhythms - September 29, 2009 Category: Neurology Authors: Hikari YOSHITANE, Yoshitaka FUKADA Source Type: journals

SymposiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 23, 2009 Category: Neurology Tags: Visions of the Night: Sleep, Science and Research on the World Stage. Australasian Sleep Association and Australasian Sleep Technologies Association 21st Annual Scientific Meeting, 8 & #x2013;10 October 2009, Sofitel Hotel, Melbourne, Victoria, Austra Source Type: journals

RNA interference is a powerful tool for chronobiological study in the cricketEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Circadian rhythms are periodic phenomena recurring with a period of about 24 h that are observed in a variety of physiological functions. The rhythms are driven by an endogenous timing system involving the circadian clock. While recent molecular studies promoted understanding the oscillatory mechanism of the clock in model organisms such as Drosophila, its applicability to other insects still remains to be examined. RNA interference (RNAi) becomes a powerful method to dissect the clock and clock-related mechanisms in non-model insects. Crickets are particularly suitable for the application of RNAi, because a single injecti...
Source: Sleep and Biological Rhythms - September 10, 2009 Category: Neurology Authors: Kenji TOMIOKA, Tomoaki SAKAMOTO, Yoshiyuki MORIYAMA Source Type: journals

Circadian regulation of olfaction and olfactory learning in the cockroach Leucophaea maderaeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Olfaction is a dominant sensory cue in both vertebrates and invertebrates and, particularly in insects, it often provides critical information utilized in a variety of well-studied behaviors including reproduction, feeding, host-identification, and intra-specific competition. Here I review recent studies on circadian regulation of olfactory receptors and olfactory behaviors in the cockroach Leucophaea maderae. Cockroaches exhibit a robust circadian rhythm in the olfactory response of the antenna, measured by electroantennogram or single-sensillum recording, to both food-related odors and sex pheromone components. Interesti...
Source: Sleep and Biological Rhythms - September 10, 2009 Category: Neurology Authors: Terry L PAGE Source Type: journals

Author IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 8, 2009 Category: Neurology Tags: Visions of the Night: Sleep, Science and Research on the World Stage. Australasian Sleep Association and Australasian Sleep Technologies Association 21st Annual Scientific Meeting, 8 & #x2013;10 October 2009, Sofitel Hotel, Melbourne, Victoria, Austra Source Type: journals

Poster presentationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 8, 2009 Category: Neurology Tags: Visions of the Night: Sleep, Science and Research on the World Stage. Australasian Sleep Association and Australasian Sleep Technologies Association 21st Annual Scientific Meeting, 8 & #x2013;10 October 2009, Sofitel Hotel, Melbourne, Victoria, Austra Source Type: journals

Oral presentationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 8, 2009 Category: Neurology Tags: Visions of the Night: Sleep, Science and Research on the World Stage. Australasian Sleep Association and Australasian Sleep Technologies Association 21st Annual Scientific Meeting, 8 & #x2013;10 October 2009, Sofitel Hotel, Melbourne, Victoria, Austra Source Type: journals

Hastatoside and verbenalin are sleep-promoting components in Verbena officinalisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we examined the sleep-promoting activity of hastatoside, verbenalin, and verbascoside, which are the major iridoids (hastatoside and verbenalin) and polyphenol (verbascoside) components responsible for the pharmacological activity of V. officinalis, by electroencephalographic analysis of rats after oral administration of the compounds. Hastatoside (0.64 mmol/kg of body weight) and verbenalin (1.28 mmol/kg of body weight) increased the total time of non-rapid eye movement sleep during a 9-h period from 23.00 to 08.00 hours by 81% and 42%, respectively, with a lag time of about 3[ndash]5 h after the administra...
Source: Sleep and Biological Rhythms - August 17, 2009 Category: Neurology Authors: Yuki MAKINO, Shino KONDO, Yoshiko NISHIMURA, Yoshinori TSUKAMOTO, Zhi-Li HUANG, Yoshihiro URADE Source Type: journals

Epidemiological study of nightmare and sleep paralysis among Japanese adolescentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we have elucidated the prevalence of and factors associated with nightmares and sleep paralysis in Japanese adolescents. We conducted a survey of first-year senior high school students by employing self-administered questionnaires about nightmare and sleep paralysis. All the subjects were first-year students (1164) from three private high schools. The responses of the remaining 916 subjects (568 boys and 348 girls) were considered valid. We found that in Japanese adolescents, the current prevalence of nightmares is 27.4%, and that of sleep paralysis is 7.2%. The lifetime prevalence of sleep paralysis is 30.4...
Source: Sleep and Biological Rhythms - August 3, 2009 Category: Neurology Authors: Takeshi MUNEZAWA, Yoshitaka KANEITA, Eise YOKOYAMA, Hiroyuki SUZUKI, Takashi OHIDA Source Type: journals

Efficacy study of a vest-type device for positional therapy in position dependent snorersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, positional therapy using the recently developed vest-type device is effective at decreasing snoring without subjective and objective adverse effects in position-dependent snorers with or without mild obstructive sleep apnea. (Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - August 2, 2009 Category: Neurology Authors: Ji Ho CHOI, Young Hwan PARK, Jung Hwa HONG, Se Joong KIM, Dong Sun PARK, Soichiro MIYAZAKI, Seung Hoon LEE, Chol SHIN, JungBok LEE Source Type: journals

Efficacy and safety of temperature data loggers in measuring compliance with the use of oral appliancesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to verify the cytotoxicity of a temperature data logger (Thermochron iButton, DS1921G; Maxim, Dallas, TX, USA) and to show the clinical use of such loggers in measuring compliance with oral appliances (OA). In the first experimental study (in vitro cytotoxicity test), we used Testskin (Toyobo, Osaka, Japan) to examine the influence on cytotoxicity caused by use of a temperature data logger (Thermochron) in a human dermal tissue model. The cytotoxicity of extracted fluid in which Thermochron was immersed was calculated and only minimal cytotoxic effects were observed. In the second study, six p...
Source: Sleep and Biological Rhythms - August 2, 2009 Category: Neurology Authors: Yoshimi INOKO, Ken YOSHIMURA, Chihomi KATO, Osami MORITA, Masaki KOHNO Source Type: journals

Excessive daytime sleepiness in obstructive sleep apnea patients after home CPAP treatment: A long-term outcome studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Previous studies have been inconclusive about the improvement in excessive daytime sleepiness (EDS) after continuous positive airway pressure (CPAP) treatment. One hundred and thirty-one obstructive sleep apnea patients, who were on regular home CPAP treatment, were investigated with an overnight polysomnography and daytime multiple sleep latency test (MSLT). Their Epworth Sleepiness Scale (ESS) scores and mean sleep latencies (MSL) before and after treatment were compared. With a mean duration of CPAP treatment for 3.4 ± 2.4 years, improvement in both ESS (12.8 to 9.95) and MSLT (7.32 to 8.92 min) were found (P < 0.001)....
Source: Sleep and Biological Rhythms - August 2, 2009 Category: Neurology Authors: Samson Yat-yuk FONG, Crover Kwok-Wah HO, Albert Martin LI, Yun-Kwok WING Source Type: journals

Effects of habitual self-awakening on nocturnal sleep, autonomic activity prior to awakening, and subjective condition after awakeningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some people habitually wake up at a certain time every morning, in the absence of an external signal. People who are engaged in this "habitual self-awakening" reportedly feel better upon awakening and are subsequently less sleepy during the daytime. The present study examined the effects of habitual self-awakening on sleep structure and autonomic nervous system activity before awakening, and on mood after awakening. Data were analyzed from 11 university students who successfully awoke within 30 min of the target time in the self-awakening condition. These same students also participated in a forced-awakening condition. All...
Source: Sleep and Biological Rhythms - May 23, 2009 Category: Neurology Authors: Noriko MATSUURA, Mitsuo HAYASHI Source Type: journals

A retrospective analysis of 4000 patients with obstructive sleep apnea in Okinawa, JapanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The causes and risks of death, and role of severity of obstructive sleep apnea (OSA), obesity, and pulmonary function (PF) in OSA patients treated with or without continuous positive airway pressure (CPAP) have been questioned. Using the Okinawa Nakamura Sleep (ONSLEEP) registry, we studied 4000 patients with an obstructive apnea-hypopnea index (AHI) of >5 events/h. Kaplan[ndash]Meier analysis determined survival rates based on use of CPAP therapy and OSA severity. Multivariate Cox proportional hazard analysis determined effects of AHI, body mass index (BMI), PF, and use of CPAP. A total of 135 deaths (3.4%) were registere...
Source: Sleep and Biological Rhythms - May 10, 2009 Category: Neurology Authors: Hiroshi NAKAMURA, Takashi KANEMURA, Chikashi TAKARA, Akira TSUKAYAMA, Kazuyo TOHYAMA, Tsuyoshi MATSUMOTO, Kunitoshi ISEKI Source Type: journals

Effects of red ginseng extract on sleep architecture and electroencephalogram power spectra in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We evaluated the ability of the ethanol extract of red ginseng (RGE) to regulate sleep architecture. Adult rats were chronically fitted with sleep[ndash]wake recording electrodes. Following post-surgical recovery, rats were habituated extensively to freely moving polygraphic recording conditions. Polygraphic signs of undisturbed sleep[ndash]wake activities were recorded for 12 h after RGE administration. Ginseng treatment produced more time in non-rapid eye movement (NREM) sleep and total sleep. The total percentage of wakefulness decreased comparably, and the number of sleep[ndash]wake cycles was reduced after 10 and 50 m...
Source: Sleep and Biological Rhythms - May 7, 2009 Category: Neurology Authors: Yuan MA, Yun B KIM, Sang Y NAM, Jae-Hoon CHEONG, Se H PARK, Hae J KIM, Jin T HONG, Ki-Wan OH Source Type: journals

Sleep patterns and sleep problems among Egyptian school children living in urban, suburban, and rural areasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, sleep duration was shorter than that reported in previous studies. Sleep problems are fairly common among elementary school children in the Giza governorate, whether in urban, suburban, or rural areas. Paternal level of education has an impact on the prevalence of sleep problems. (Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - May 5, 2009 Category: Neurology Authors: Maha K ABOU-KHADRA Source Type: journals

Circadian rhythm sleep disorders: An updateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The primary symptom of circadian rhythm sleep disorders (CRSDs) is the inability to sleep during the desired sleep time. CRSDs are divided into two broad classes: (i) disorders not related to forced alterations of the sleep[ndash]wake schedule or light[ndash]dark cycle (including advanced sleep phase disorder [ASPD], delayed sleep phase disorder [DSPD], non-entrained type [NET], and irregular sleep[ndash]wake rhythm [ISWR]); and (ii) disorders related to forced alterations of the sleep[ndash]wake schedule or light[ndash]dark cycle (including shift work sleep disorder [SWSD], jet lag disorder [JLD], and CRSDs related to dis...
Source: Sleep and Biological Rhythms - May 5, 2009 Category: Neurology Authors: Bhavneesh SHARMA, Steven FEINSILVER Source Type: journals

Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in JapanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Donepezil 10 mg/day gained approval in Japan in August 2007 for the treatment of cognitive dysfunction in advanced Alzheimer's disease. We evaluated the efficacy and adverse effects of donepezil when the dose was increased to 10 mg/day in 61 Japanese patients with Alzheimer's disease. Cognitive function was evaluated using the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental State Examination (MMSE) on the day before starting, and at 4, 8, and 24 weeks after starting donepezil 10 mg/day. The relationship with apolipoprotein E4 was also investigated. The HDS-R and MMSE scores were not statistically significantly diff...
Source: Sleep and Biological Rhythms - April 8, 2009 Category: Neurology Authors: Motohiro NOZAWA, Yosuke ICHIMIYA, Eiko NOZAWA, Yushi UTUMI, Hideki SUGIYAMA, Norio MURAYAMA, Eizo ISEKI, Heii ARAI Source Type: journals

Absence of anti-aquaporin-4 antibodies in narcolepsyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we screened for anti-AQP4 antibodies in sera from 251 patients with narcolepsy, 34 with other hypersomnias, and 200 healthy controls by using the radioligand binding assay method. A positive result for anti-AQP4 antibodies was found only in one healthy control subject. All the hypersomnia patients were negative for this antibody. Our results indicated that anti-AQP4 antibody is not useful as a diagnostic marker for narcolepsy and other hypersomnias. (Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - April 4, 2009 Category: Neurology Authors: Susumu TANAKA, Minae KAWASHIMA, Makoto HONDA Source Type: journals

Emergence of the circadian sleep–wake rhythm might depend on conception not on birth timingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Developmental changes in the sleep[ndash]wake rhythm of preterm infants were compared with those of full-term infants, to clarify the timing of the developmental change of the sleep[ndash]wake rhythm and its dependence on either conception or birth timing. We obtained sleep log data for two preterm infants, and compared these with previous data gathered from 10 full-term infants over a period from 2 weeks after birth to 3 months after their expected delivery dates. Infant sleep logs were analyzed with the autocorrelation method to investigate the development of the circadian rhythm in each infant's sleep patterns during ea...
Source: Sleep and Biological Rhythms - March 17, 2009 Category: Neurology Authors: Rieko TAKAYA, Kazuhiko FUKUDA, Hiroko UEHARA, Hideki KIHARA, Kaneyoshi ISHIHARA Source Type: journals

AnnouncementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - March 12, 2009 Category: Neurology Tags: Announcement Source Type: journals

Restless legs syndrome in a 5-year-old boy with low body stores of ironEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 5-year-old preschooler with RLS, who presented with an uncomfortable sensation in his toes before bedtime and insomnia. Blood tests showed reduced iron stores (serum ferritin, 15.9 ng/mL). The subjective symptoms and a maternal history of RLS were consistent with pediatric RLS. Iron supplement therapy resulted in improvement in the leg sensation and subjective daytime alertness. We recommend detailed evaluation of iron status in preschoolers with suspected RLS. (Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - March 12, 2009 Category: Neurology Authors: Katsuhisa BANNO, Shigefumi KOIKE, Katsunori YAMAMOTO Tags: Short Paper Source Type: journals

Evaluation of the usefulness of the SleepStrip for screening obstructive sleep apnea-hypopnea syndrome in JapanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to assess the usefulness of the SleepStrip (SS) in screening for obstructive sleep apnea-hypopnea syndrome (OSAHS) in Japanese settings, we measured its sensitivity and specificity against the reference standard diagnostic full-night polysomnography (FN-PSG) using a real-life timeline, and compared them to that of the simultaneously applied pulse oximeter (PO), a routinely used OSAHS screener in Japan. A total of 110 consecutive subjects with the symptoms of OSAHS underwent simultaneous SS and PO screening tests followed by a diagnostic FN-PSG within 7 weeks, a common time frame for accessing PSG in Japan. Data fo...
Source: Sleep and Biological Rhythms - March 8, 2009 Category: Neurology Authors: Viktor GERGELY, Henrik PALLOS, Kunihiro MASHIMA, Soichiro MIYAZAKI, Toshihiko TANAKA, Masako OKAWA, Naoto YAMADA Source Type: journals

The effects of a 30-min nap during night shift following a prophylactic sleep in the afternoonEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to investigate the effects of a 30-min nap, during a simulated night shift environment, when a prophylactic daytime sleep was implemented prior to the night shift. A repeated-measures counterbalanced design was used which included two experimental conditions: a 30-min nap and a no nap control. In both conditions subjects obtained a 2-h sleep in the afternoon from 15.00[ndash]17.00 hours, which was followed by the night-time nap from 02.30[ndash]03.00 hours in a controlled laboratory environment. Post-nap testing was conducted from 03.10 to 07.00 hours. The participants included 22 adults aged ...
Source: Sleep and Biological Rhythms - February 17, 2009 Category: Neurology Authors: Nicole LOVATO, Leon LACK, Sally FERGUSON, Rebecca TREMAINE Source Type: journals

Good esthetic results after modified maxillomandibular advancement for obstructive sleep apnea syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recently, obstructive sleep apnea syndrome (OSAS) is commonly treated conservatively, in particular with continuous positive airway pressure and oral appliance. However, these methods provide only symptomatic relief, and compliance is low. On the other hand, various types of surgical treatment for OSAS have been reported, and maxillomandibular advancement (MMA) is one of the best established and most effective surgical therapies available to improve this condition. However, a major disadvantage of this method is that advancement of the maxilla-mandibular component sometimes has undesired esthetic results. We encountered a ...
Source: Sleep and Biological Rhythms - January 22, 2009 Category: Neurology Authors: Akira MATSUO, Takayuki NAKAI, Jun TOYODA, Hidetoshi TAKAHASHI, Iwao SUZUKI, Hiroshige CHIBA Source Type: journals

How is autonomic nervous system activity in subjects who are sleepy but are unable to sleep in the daytime?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We investigated changes in the activity of the autonomic nervous system (ANS) in the relaxed condition in subjects who felt sleepy, but were unable to sleep. A total of 1021 subjects underwent daytime polysomnography. The sleep latency (SL) and the visual analog scale (VAS) were used to assess "immediate" objective and subjective sleepiness, respectively. The subjects were assigned to an "Alert-Alert" group (VAS [le] 25 mm, SL [ge] 8 min), a "Sleepy-Alert" group (VAS [ge] 75 mm, SL [ge] 8 min), or a "Sleepy-Sleepy" group (VAS [ge] 75 mm, SL [le] 4 min). In order to assess the ANS, the spectral analysis and the geometric me...
Source: Sleep and Biological Rhythms - January 20, 2009 Category: Neurology Authors: Hiroko MORISHIMA, Emiko SUGIYAMA, Masateru MATSUSHITA, Shigehiko URUHA, Satoko ITO, Yukari ABE, Momoko NISHITANI, Takuya WATANABE, Nakamori SUGANUMA, Schuhei YAMAMURA, Kentarou YANAGI, Yoshihisa SHIGEDO, Takayuki KUMANO-GO, Hiroyoshi ADACHI, Akira MIKAMI, Source Type: journals

The relationship between subjective sleep disturbance and complexity of 24-hour activity utilizing fractal theory in psychiatric inpatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human activity is very complex, so the assumptions employed when analyzing models do not give fully satisfactory results. Fractal theory made possible the quantification of the complexity of objects in terms of fractal dimension (FD). We revealed a correlation between the pattern of 24-h activity and subjective sleep disturbance using the Pittsburgh Sleep Quality Index (PSQI). Seven men and 13 women who are inpatients suffering from psychiatric disorders participated in this study. Wrist activity was monitored with an actigraph for 24 h. The data sampling period was 1 min and the data were transferred to a PC for fractal a...
Source: Sleep and Biological Rhythms - January 18, 2009 Category: Neurology Authors: Mari YAMAHARA, Toshifumi NOGUCHI, Masako OKAWA, Naoto YAMADA Source Type: journals

Newly developed waist actigraphy and its sleep/wake scoring algorithmEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to formulate an algorithm for assessing sleep/waking from activity intensities measured with a waist-worn actigraphy, the Lifecorder PLUS (LC; Suzuken Co. Ltd., Nagoya, Japan), and to test the validity of the algorithm. The study consisted of 31 healthy subjects (M/F = 20/11, mean age 31.7 years) who underwent one night of simultaneous measurement of activity intensity by LC and polysomnography (PSG). A sleep(S)/wake(W) scoring algorithm based on a linear model was determined through discriminant analysis of activity intensities measured by LC over a total of 235 h and 56 min and the correspon...
Source: Sleep and Biological Rhythms - January 18, 2009 Category: Neurology Authors: Minori ENOMOTO, Takuro ENDO, Kazue SUENAGA, Naoki MIURA, Yasushi NAKANO, Sayaka KOHTOH, Yujiro TAGUCHI, Sayaka ARITAKE, Shigekazu HIGUCHI, Masato MATSUURA, Kiyohisa TAKAHASHI, Kazuo MISHIMA Source Type: journals

Pathogenetic heterogeneity of restless legs syndrome in Parkinson's diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to clarify the pathogenetic heterogeneity of restless legs syndrome (RLS), we compared the clinical characteristics of RLS between six patients with young-onset Parkinson's Disease (PD) and 30 with elderly-onset PD. Young-onset PD showed longer periods from the onset of PD to that of RLS than elderly-onset PD, despite a similar severity between the two groups. The rate of subjects with disappearance of RLS at the follow-up observations was significantly higher in the former group. These results suggested that RLS in young-onset PD could be milder and more transient than that in elderly-onset PD. (Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - January 18, 2009 Category: Neurology Authors: Takashi NOMURA, Yuichi INOUE, Kenji NAKASHIMA Source Type: journals

Subject IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Tags: Subject Index Source Type: journals

Adolescent napping behavior: Dysfunctional cognitions and negative affectEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study compared the dysfunctional cognitions and negative affect of adolescent nappers and non-nappers. Participants were 231 adolescents (mean age, 17.7 years) who completed sleep, cognition, and negative affect questionnaires. Adolescent nappers demonstrated significantly more dysfunctional cognitions (P = 0.01), anxiety (P < 0.01), and stress symptoms (P < 0.01), when compared to non-nappers. In contrast, no significant difference was found for depression (P = 0.18). Furthermore, adolescent nappers with more severe dysfunctional cognitions demonstrated greater negative affect (all P < 0.05). The present study is one...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Michael GRADISAR, Hayley DOHNT, Helen WRIGHT, Julie ROBINSON, Sarah PAINE, Amanda GAMBLE Tags: Original Articles Source Type: journals

Electroencephalogram activity before self-awakeningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It has been reported that self-awakening, the ability to awaken without using an alarm at a predetermined time, can reduce sleep inertia immediately after awakening. To clarify the psychophysiological mechanisms underlying this effect, electroencephalogram activity was analyzed for 90 min before awakening on forced- and self-awakening nights for eight participants (21[ndash]23 years). The results showed that sigma band power, which reflects sleep spindle activity, gradually decreased during sleep stage 2 before awakening under self-awakening conditions. The previous finding that sleep spindles are involved in the function ...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Hiroki IKEDA, Mitsuo HAYASHI Tags: Original Articles Source Type: journals

Analysis of non-REM sleep staging with electroencephalography bispectral indexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study provides results in an early sleep period for non-REM stage correlation with bispectral index (BIS) values. The purpose of the study was to assess the applicability of an objective procedure to monitor sleep. Nine healthy subjects (mean age: 25.0 ± 4.4; 1 female) were recruited for the study without history of any neurological, psychiatric, or sleep-related disorders. Electroencephalography (EEG) signals from 30 electrodes referenced to linked earlobe electrodes, and electrooculography (EOG) and electromyography (EMG) activities were recorded. BIS recording was performed simultaneously with EEG recording...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Murat ÖZGÖREN, Sibel KOCAASLAN, Adile ÖNİZ Tags: Original Articles Source Type: journals

Restless legs syndrome is related to difference in tibial muscle tone in the evening, late at night, and morningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study the measurement test included a 20-minute lying period in the supine position before the measurement was made. The patient was lying on the bed with his or her legs stretched out and relaxed. MYO measurements indicated that the frequency of damped oscillation in the tibial muscle in RLS patient (19.2 ± 3.1 Hz) is higher than in normal subjects (14.8 ± 1.2 Hz); P < 0.001. The study indicated that tissue stiffness of the tibial muscle in RLS patients increases in the evening and late at night while it decreased in the normal subjects. The neurological mechanism why the tone of the tibial muscles increases dur...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Marlit VELDI, Arved VAIN, Veiko VASAR, Mart KULL, Markku PARTINEN Tags: Original Articles Source Type: journals

Performance prediction by sleepiness-related subjective symptoms during 26-hour sleep deprivationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sleepiness is a major cause of lower productivity and higher risk of accidents in various work situations. Developing sleepiness monitoring techniques is important to improve work efficiency and to reduce accident risk, so that people can take a rest/break in appropriate timing before an accident or a mistake occurs. The aims of the present study are (1) to explain subjective sleepiness using sleep-related symptoms, and (2) to examine which symptoms are useful to predict performance errors. Participants were healthy paid volunteers (six males, six females; mean ± SD, 31.5 ± 10.74 years). Participants took part in 26-h sl...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Kosuke KAIDA, Torbjörn ÅKERSTEDT, Masaya TAKAHASHI, Peter VESTERGREN, Mats GILLBERG, Arne LOWDEN, Göran KECKLUND, Christian PORTIN Tags: Original Articles Source Type: journals

Diurnal variation of physical and mental fatigueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Diurnal effects on fatigue are well established. However, evidence exists that fatigue can be subdivided into physical and mental components. Diurnal effects on these subcomponents of fatigue are not known. The present study served to investigate diurnal influences on physical and mental signs of fatigue. A number of self-report measures of sleepiness, and physical and mental signs of fatigue were employed, including a specially developed questionnaire designed to assess current feelings of physical and mental fatigue. The responses from 40 subjects were assessed in the morning, at noon, and in the evening. Sleepiness as w...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Reinhard PIETROWSKY, Olaf LAHL Tags: Original Articles Source Type: journals

An investigation of the dimensionality of the Pittsburgh Sleep Quality Index in Australian adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Pittsburgh Sleep Quality Index (PSQI) is widely used to assess subjective sleep quality in clinical and non-clinical settings. Although the PSQI is routinely scored to provide a single sleep quality factor, two recent studies suggest that multiple factor scoring methods could be more appropriate. As a consequence, the present study investigated for the dimensionality and factor structure of the PSQI in 364 Australian adults aged 18 to 59 years. The results demonstrate that two factor and three factor scoring models were favored statistically over the single factor model. These results add to recent findings and suggest...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Christopher A MAGEE, Peter CAPUTI, Donald C IVERSON, Xu-Feng HUANG Tags: Original Articles Source Type: journals

Continuous recording of autonomic nervous activity at nighttime effectively explains subjective sleep reports in postmenopausal womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To investigate the effect of nocturnal autonomic nervous activity on subjective sleep reports, a combined recording using an actigraph and a wristwatch-type pulse wave sensor was carried out. The participants included 19 healthy menopausal women (mean age: 57.3 ± 3.85 years) without menopausal syndrome. Total sleep time (TST) and wake time after sleep onset (WASO) data were acquired from the actigraph. Indices of parasympathetic and sympathetic nervous activity (high frequency [HF] and percentile of low frequency [%LF]) during sleep were calculated by the pulse frequency demodulation method. Subsequently, we investigated ...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Madoka TAKAHARA, Koh MIZUNO, Kazuhiro HIROSE, Kazuhiro SAKAI, Katsuyoshi NISHII, Minoru ONOZUKA, Sadao SATO, Shuichiro SHIRAKAWA Tags: Original Articles Source Type: journals

Progressive changes in sleep electroencephalogram dynamics in the rat barrel cortex associated with long-term alternation of sensory input activitiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sleep is suggested to be involved in the development and maintenance of neural networks. We investigated how long-term alternation of somatosensory input activities affects electroencephalogram (EEG) dynamics of adult rats during non-REM sleep (NREM). Power spectral densities of NREM EEG activity were analyzed for 10 days under the alternation of sensory input activities caused by unilateral whisker clipping. The progressive reduction of the delta power of the inactivated side of the barrel cortex relative to the activated side was found in terms of the daily mean. This extends our previous study in which only the initial ...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Naoko IWASAKI, Akihiro KARASHIMA, Norihiro KATAYAMA, Mitsuyuki NAKAO Tags: Original Articles Source Type: journals

Status of narcolepsy-related information available on the Internet in Japan and its effective useEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Narcolepsy patients often access the Internet using key words mostly consisting of common symptoms in order to further learn about their disease. Although information from diverse sources floods the Internet, the quality of narcolepsy-related information appears to have improved, and harmful information does not often enter the top access rankings. Narcolepsy patients consider the information available on the Internet as being useful and wish to know more about new treatments, drugs, and the situation of other narcolepsy patients. The time from the onset of the symptoms to a definitive diagnosis has been significantly shor...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Rika AIZAWA, Hideki SUNAHARA, Kazuhiko KUME, Satoshi TSUCHIYA, Hiroyoshi ADACHI, Takashi KANBAYASHI, Tetsuo SHIMIZU Tags: Original Articles Source Type: journals

Sleepiness in multiple sclerosis: A pilot studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study examined sleepiness and sleep-related factors using polysomnography. This cohort-controlled, ethics-approved, pilot study compared 12 MS patients, divided into two groups (with and without daytime sleepiness [ndash] assessed with the Epworth Sleepiness Scale [ESS], Fatigue Severity Scale, and Fatigue Impact Scale), with 14 controls presenting for assessment of fatigue. All underwent polysomnography, with MS patients also undergoing multiple sleep latency testing, drug screening, and expanded disability-status scale evaluation. Statistical analysis used non-parametric comparisons. Based on the ESS, with the cut-o...
Source: Sleep and Biological Rhythms - November 27, 2008 Category: Neurology Authors: Roy G BERAN, Laetitia AE AINLEY, Gerard HOLLAND Tags: Original Articles Source Type: journals

PrefaceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - October 1, 2008 Category: Neurology Authors: Yoshimasa KOYAMA Tags: Preface Source Type: journals

SymposiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 2, 2008 Category: Neurology Tags: 20th Annual Scientific Meeting of the Australasian Sleep Association and the 20th Annual Scientific Meeting of the Australasian Sleep Technologists Association 2 & #x2013;4 October, 2008 Adelaide, Australia Source Type: journals

Author IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 1, 2008 Category: Neurology Tags: 20th Annual Scientific Meeting of the Australasian Sleep Association and the 20th Annual Scientific Meeting of the Australasian Sleep Technologists Association 2 & #x2013;4 October, 2008 Adelaide, Australia Source Type: journals

Poster PresentationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Sleep and Biological Rhythms)
Source: Sleep and Biological Rhythms - September 1, 2008 Category: Neurology Tags: 20th Annual Scientific Meeting of the Australasian Sleep Association and the 20th Annual Scientific Meeting of the Australasian Sleep Technologists Association 2 & #x2013;4 October, 2008 Adelaide, Australia Source Type: journals