The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells
Publication date: Available online 8 July 2021Source: Stem Cell ReportsAuthor(s): Rebecca L. Murdaugh, Kevin A. Hoegenauer, Ayumi Kitano, Matthew V. Holt, Matthew C. Hill, Xiangguo Shi, Jonathan F. Tiessen, Richard Chapple, Tianyuan Hu, Yu-Jung Tseng, Angelique Lin, James F. Martin, Nicolas L. Young, Daisuke Nakada (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 9, 2021 Category: Stem Cells Source Type: research

Dysregulated ECM remodeling proteins lead to aberrant osteogenesis of Costello syndrome iPSCs
Publication date: Available online 8 July 2021Source: Stem Cell ReportsAuthor(s): Jong Bin Choi, Joonsun Lee, Minyong Kang, Bumsoo Kim, Younghee Ju, Hyo-Sang Do, Han-Wook Yoo, Beom Hee Lee, Yong-Mahn Han (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 9, 2021 Category: Stem Cells Source Type: research

Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs
Publication date: Available online 8 July 2021Source: Stem Cell ReportsAuthor(s): Parvin Valiulahi, Vincencius Vidyawan, Lesly Puspita, Youjin Oh, Virginia Blessy Juwono, Panida Sittipo, Gilgi Friedlander, Dayana Yahalomi, Jong-Woo Sohn, Yun Kyung Lee, Jeong Kyo Yoon, Jae-won Shim (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 9, 2021 Category: Stem Cells Source Type: research

Improved hematopoietic stem cell transplantation upon inhibition of natural killer cell-derived interferon-gamma
Publication date: Available online 8 July 2021Source: Stem Cell ReportsAuthor(s): Lorena Lobo de Figueiredo-Pontes, Miroslava K. Adamcova, Srdjan Grusanovic, Maria Kuzmina, Izabela Aparecida Lopes, Amanda Fernandes de Oliveira Costa, Hong Zhang, Hynek Strnad, Sanghoon Lee, Alena Moudra, Anna T. Jonasova, Michal Zidka, Robert S. Welner, Daniel G. Tenen, Meritxell Alberich-Jorda (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 9, 2021 Category: Stem Cells Source Type: research

Derivation of feeder-free human extended pluripotent stem cells
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Ran Zheng, Ting Geng, Dan-Ya Wu, Tianzhe Zhang, Hai-Nan He, Hai-Ning Du, Donghui Zhang, Yi-Liang Miao, Wei Jiang (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Synaptic repair and vision restoration in advanced degenerating eyes by transplantation of retinal progenitor cells
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Xiang-Yu He, Cong-Jian Zhao, Haiwei Xu, Kang Chen, Bai-Shi-Jiao Bian, Yu Gong, Chuan-Huang Weng, Yu-Xiao Zeng, Yan Fu, Yong Liu, Zheng-Qin Yin (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Nikolajs Zeps, Tamra Lysaght, Ruth Chadwick, Alexandre Erler, Roger Foo, Simona Giordano, Poh San Lai, G. Owen Schaefer, Vicki Xafis, Wei Leong Chew, Jeremy Sugarman (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Human pluripotent stem cell-derived eosinophils reveal potent cytotoxicity against solid tumors
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Weifeng Lai, Huangfan Xie, Yuting Liu, Feng Zheng, Yingfeng Zhang, Qi Lei, Lejun Lv, Jiebin Dong, Jian Song, Xue Gao, Ming Yin, Chengyan Wang, Hongkui Deng (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Recognizing the ethical implications of stem cell research: A call for broadening the scope
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Lars S. Assen, Karin R. Jongsma, Rosario Isasi, Marianna A. Tryfonidou, Annelien L. Bredenoord (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells
Publication date: Available online 1 July 2021Source: Stem Cell ReportsAuthor(s): Scott Bell, Vincent McCarty, Huashan Peng, Malvin Jefri, Nuwan Hettige, Lilit Antonyan, Liam Crapper, Liam A. O'Leary, Xin Zhang, Ying Zhang, Hanrong Wu, Diane Sutcliffe, Ilaria Kolobova, Thad A. Rosenberger, Luc Moquin, Alain Gratton, Jelena Popic, Ilse Gantois, Patrick S. Stumpf, Andreas A. Schuppert (Source: Stem Cell Reports)
Source: Stem Cell Reports - July 2, 2021 Category: Stem Cells Source Type: research

Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics
Publication date: Available online 24 June 2021Source: Stem Cell ReportsAuthor(s): Yi Han Ng, Soham Chanda, Justyna A. Janas, Nan Yang, Yuko Kokubu, Thomas C. Südhof, Marius Wernig (Source: Stem Cell Reports)
Source: Stem Cell Reports - June 25, 2021 Category: Stem Cells Source Type: research

Uncoupling key determinants of hematopoietic stem cell engraftment through cell-specific and temporally controlled recipient conditioning
Publication date: Available online 24 June 2021Source: Stem Cell ReportsAuthor(s): Natsumi Miharada, Anna Rydström, Justyna Rak, Jonas Larsson (Source: Stem Cell Reports)
Source: Stem Cell Reports - June 25, 2021 Category: Stem Cells Source Type: research

Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1
Publication date: Available online 24 June 2021Source: Stem Cell ReportsAuthor(s): Meiling Zhou, Xiaoqing Tao, Ming Sui, Mengge Cui, Dan Liu, Beibei Wang, Ting Wang, Yunjie Zheng, Juan Luo, Yangling Mu, Feng Wan, Ling-Qiang Zhu, Bin Zhang (Source: Stem Cell Reports)
Source: Stem Cell Reports - June 25, 2021 Category: Stem Cells Source Type: research

Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium
Publication date: Available online 24 June 2021Source: Stem Cell ReportsAuthor(s): Alun Vaughan-Jackson, Szymon Stodolak, Kourosh H. Ebrahimi, Cathy Browne, Paul K. Reardon, Elisabete Pires, Javier Gilbert-Jaramillo, Sally A. Cowley, William S. James (Source: Stem Cell Reports)
Source: Stem Cell Reports - June 25, 2021 Category: Stem Cells Source Type: research

Auxin-degron system identifies immediate mechanisms of OCT4
Publication date: Available online 17 June 2021Source: Stem Cell ReportsAuthor(s): Lawrence E. Bates, Mariana R.P. Alves, José C.R. Silva (Source: Stem Cell Reports)
Source: Stem Cell Reports - June 18, 2021 Category: Stem Cells Source Type: research