Table of Contents : Hepatitis B Annual : 2004 - 1(1)
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Hepatitis B viral infection: Emerging issues
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Shivaram Prasad Singh, Yogesh Kumar ChawlaHepatitis B Annual 2007 4(1):7-11
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Shivaram Prasad Singh, Yogesh Kumar Chawla Source Type: journals
Hepatitis B virus and pregnancy
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Silvia SookoianHepatitis B Annual 2007 4(1):12-23Hepatitis B virus (HBV) infection is very common, with over 350 million chronically infected people worldwide. This review plans to answer some key questions regarding hepatitis B infection during pregnancy, in order to provide healthcare professionals with updated information on the current knowledge in this field. The focus is on the following topics: the main risk factors associated with vertical transmission of HBV in pregnant women who are chronically infected, the influence of pregnancy on HBV viral load, and the effect of pregnancy on the clinical course of chronic he...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Silvia Sookoian Source Type: journals
HBV drug resistance : Its relevance in clinical practice
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Rajib Kishore Hazam, Premashis KarHepatitis B Annual 2007 4(1):24-39Drug resistance can be considered as a natural response to the selective pressure of the drug. An increase in HBV DNA can be a good indicator of the presence of a resistant HBV mutant population. The nucleoside analogues Lamivudine, Adefovir, Entecavir etc. are oral drugs used for Hepatitis B viral infection. Resistance to HBV drugs arises due to mutations in the polymerase gene. The HBV polymerase can be divided into 4 domains: 1) the terminal protein, 2) the variable spacer domain, 3) the polymerase/reverse transcriptase and 4) the RNase. Drug resistance...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Rajib Kishore Hazam, Premashis Kar Source Type: journals
Hepatitis B virus serology: Use and interpretation
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This article reviews the clinical use of serologic and nucleic acid tests as markers of disease activity.
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Sunil M Shah, Shivaram Prasad Singh Source Type: journals
Hepatitis B vaccine induced HBsAg positivity
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Shivaram Prasad SinghHepatitis B Annual 2007 4(1):55-60Hepatitis B vaccine can induce transient hepatitis B surface antigen positivity not only in adult hemodialysis patients but also in normal adults and children. Hence hepatitis B vaccinees may be mistaken for confirmed hepatitis B surface antigen-positive carrier. Hence blood donors should not donate blood in this early post-vaccination period and renal dialysis patients should not be screened for hepatitis B surface antigen for at least 21 to 28 days after hepatitis B vaccination. These guidelines could prevent individuals in the early post-inoculation period from bein...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Shivaram Prasad Singh Source Type: journals
Non-invasive markers of hepatic fibrosis in chronic Hepatitis B: A review
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Mamun Al-Mahtab, Salimur Rahman, Mobin KhanHepatitis B Annual 2007 4(1):61-71Assessment of fibrosis is important in chronic hepatitis B for a number of reasons including decision-making regarding treatment and predicting prognosis.Currently liver biopsy is considered the gold standard for assessing liver histology. However, since liver biopsy has significant limitations,the quest for a non-invasive alternative to assess hepatic fibrosis continues. A review of published literature reveals that extensive research has been carried out in this field, and several simple to complicated alternatives to liver biopsy for assessing ...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Mamun Al-Mahtab, Salimur Rahman, Mobin Khan Source Type: journals
Complementary and alternative therapies in the treatment of chronic hepatitis B
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Jia-Ming Chang, Kai-Ling HuangHepatitis B Annual 2007 4(1):72-106Hepatitis B virus (HBV) infects approximately more than 350 million people worldwide, especially in Asia, Africa, southern Europe and Latin America. Except for interferon-α, most anti-HBV drugs are derived from the anti-herpes and anti-HIV drugs. Because of the high cost of hepatitis B medications, herbs-also called 'complementary and alternative therapies' in modern Western science-are widely used for treatment of chronic hepatitis B in developing countries. Herbals confer their activities not only by inhibiting HBV secretion bu...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Jia-Ming Chang, Kai-Ling Huang Source Type: journals
Management of severe acute hepatitis B
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Sudeep Khanna, Rakesh TandonHepatitis B Annual 2007 4(1):107-117HBV infection is a major public health problem. Acute viral hepatitis B is successfully cleared in more than 95% of immunocompetent patients. HBV infection can cause severe acute hepatitis which can progress to acute liver failure. The purpose of this review is to discuss the immune response in acute hepatitis B and the possible role of HBV genotypes in development of severe acute HBV related hepatitis, define severe acute hepatitis B and to look at the role of the available antivirals in this clinical setting.
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Sudeep Khanna, Rakesh Tandon Source Type: journals
Management overview of chronic hepatitis B with established therapies
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Deepak Narayan AmarapurkarHepatitis B Annual 2007 4(1):118-132Currently available options for the treatment of chronic hepatitis B virus (HBV) infection include standard and pegylated interferon alfa and Thymosin alpha, four oral antiviral agents (lamivudine, adefovir, entecavir, and telbivudine), two agents Tenofovir and emtricitabine approved in the HIV HBV co-infection are likely to be approved for HBV infection in immediate future. These treatment strategies are either therapies of finite duration that aim to achieve sustained off-therapy responses, or long-term treatments that aim to maintain on-therapy remission. Mos...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Deepak Narayan Amarapurkar Source Type: journals
Hepatitis B: News from the research world
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Paramasivan Piramanayagam, Gourdas ChoudhuriHepatitis B Annual 2007 4(1):133-145Hepatitis B is the leading cause of viral hepatitis in the developing world; about 400 million people are infected with chronic hepatitis B worldwide. Continuing research on hepatitis B over the last few decades has added considerably to our understanding of its replication, pathology, natural history, diagnosis and treatment. This section highlights a few selected landmark research articles published during the past year in the field of Hepatitis B. These articles enhance our understanding of the basic nature of this infection and help us to t...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - July 30, 2009 Category: Hematology Authors: Paramasivan Piramanayagam, Gourdas Choudhuri Source Type: journals
Hepatitis B viral infection: Emerging issues
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Singh Shivaram Prasad, Chawla Yogesh KumarHepatitis B Annual 2007 4(1):7-11
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Singh Shivaram Prasad, Chawla Yogesh Kumar Source Type: journals
Hepatitis B virus and pregnancy
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Sookoian SilviaHepatitis B Annual 2007 4(1):12-23Hepatitis B virus (HBV) infection is very common, with over 350 million chronically infected people worldwide. This review plans to answer some key questions regarding hepatitis B infection during pregnancy, in order to provide healthcare professionals with updated information on the current knowledge in this field. The focus is on the following topics: the main risk factors associated with vertical transmission of HBV in pregnant women who are chronically infected, the influence of pregnancy on HBV viral load, and the effect of pregnancy on the clinical course of chronic he...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Sookoian Silvia Source Type: journals
HBV drug resistance : Its relevance in clinical practice
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Hazam Rajib Kishore, Kar PremashisHepatitis B Annual 2007 4(1):24-39Drug resistance can be considered as a natural response to the selective pressure of the drug. An increase in HBV DNA can be a good indicator of the presence of a resistant HBV mutant population. The nucleoside analogues Lamivudine, Adefovir, Entecavir etc. are oral drugs used for Hepatitis B viral infection. Resistance to HBV drugs arises due to mutations in the polymerase gene. The HBV polymerase can be divided into 4 domains: 1) the terminal protein, 2) the variable spacer domain, 3) the polymerase/reverse transcriptase and 4) the RNase. Drug resistance...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Hazam Rajib Kishore, Kar Premashis Source Type: journals
Hepatitis B virus serology: Use and interpretation
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This article reviews the clinical use of serologic and nucleic acid tests as markers of disease activity.
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Shah Sunil M, Singh Shivaram Prasad Source Type: journals
Hepatitis B vaccine induced HBsAg positivity
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Singh Shivaram PrasadHepatitis B Annual 2007 4(1):55-60Hepatitis B vaccine can induce transient hepatitis B surface antigen positivity not only in adult hemodialysis patients but also in normal adults and children. Hence hepatitis B vaccinees may be mistaken for confirmed hepatitis B surface antigen-positive carrier. Hence blood donors should not donate blood in this early post-vaccination period and renal dialysis patients should not be screened for hepatitis B surface antigen for at least 21 to 28 days after hepatitis B vaccination. These guidelines could prevent individuals in the early post-inoculation period from bein...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Singh Shivaram Prasad Source Type: journals
Non-invasive markers of hepatic fibrosis in chronic Hepatitis B: A review
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Al-Mahtab Mamun, Rahman Salimur, Khan MobinHepatitis B Annual 2007 4(1):61-71Assessment of fibrosis is important in chronic hepatitis B for a number of reasons including decision-making regarding treatment and predicting prognosis.Currently liver biopsy is considered the gold standard for assessing liver histology. However, since liver biopsy has significant limitations,the quest for a non-invasive alternative to assess hepatic fibrosis continues. A review of published literature reveals that extensive research has been carried out in this field, and several simple to complicated alternatives to liver biopsy for assessing ...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Al-Mahtab Mamun, Rahman Salimur, Khan Mobin Source Type: journals
Complementary and alternative therapies in the treatment of chronic hepatitis B
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Chang Jia-Ming, Huang Kai-LingHepatitis B Annual 2007 4(1):72-106Hepatitis B virus (HBV) infects approximately more than 350 million people worldwide, especially in Asia, Africa, southern Europe and Latin America. Except for interferon-α, most anti-HBV drugs are derived from the anti-herpes and anti-HIV drugs. Because of the high cost of hepatitis B medications, herbs-also called 'complementary and alternative therapies' in modern Western science-are widely used for treatment of chronic hepatitis B in developing countries. Herbals confer their activities not only by inhibiting HBV secretion bu...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Chang Jia-Ming, Huang Kai-Ling Source Type: journals
Management of severe acute hepatitis B
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Khanna Sudeep, Tandon RakeshHepatitis B Annual 2007 4(1):107-117HBV infection is a major public health problem. Acute viral hepatitis B is successfully cleared in more than 95% of immunocompetent patients. HBV infection can cause severe acute hepatitis which can progress to acute liver failure. The purpose of this review is to discuss the immune response in acute hepatitis B and the possible role of HBV genotypes in development of severe acute HBV related hepatitis, define severe acute hepatitis B and to look at the role of the available antivirals in this clinical setting.
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Khanna Sudeep, Tandon Rakesh Source Type: journals
Management overview of chronic hepatitis B with established therapies
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Amarapurkar Deepak NarayanHepatitis B Annual 2007 4(1):118-132Currently available options for the treatment of chronic hepatitis B virus (HBV) infection include standard and pegylated interferon alfa and Thymosin alpha, four oral antiviral agents (lamivudine, adefovir, entecavir, and telbivudine), two agents Tenofovir and emtricitabine approved in the HIV HBV co-infection are likely to be approved for HBV infection in immediate future. These treatment strategies are either therapies of finite duration that aim to achieve sustained off-therapy responses, or long-term treatments that aim to maintain on-therapy remission. Mos...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Amarapurkar Deepak Narayan Source Type: journals
Hepatitis B: News from the research world
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Piramanayagam Paramasivan, Choudhuri GourdasHepatitis B Annual 2007 4(1):133-145Hepatitis B is the leading cause of viral hepatitis in the developing world; about 400 million people are infected with chronic hepatitis B worldwide. Continuing research on hepatitis B over the last few decades has added considerably to our understanding of its replication, pathology, natural history, diagnosis and treatment. This section highlights a few selected landmark research articles published during the past year in the field of Hepatitis B. These articles enhance our understanding of the basic nature of this infection and help us to t...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - January 17, 2009 Category: Hematology Authors: Piramanayagam Paramasivan, Choudhuri Gourdas Source Type: journals
Treatment of chronic hepatitis B: A bridge too far
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Singh Shivaram Prasad, Chawla Yogesh KumarHepatitis B Annual 2006 3(1):7-10
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Singh Shivaram Prasad, Chawla Yogesh Kumar Source Type: journals
Hepatitis B Eradication Day: It's never too late!!
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Singh Shivaram PrasadHepatitis B Annual 2006 3(1):11-13
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Singh Shivaram Prasad Source Type: journals
Telbivudine : A new treatment option in the management of chronic hepatitis B
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Fung James, Lai Ching-Lung, Yuen Man-FungHepatitis B Annual 2006 3(1):14-34
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Fung James, Lai Ching-Lung, Yuen Man-Fung Source Type: journals
Entecavir : A review
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Tan Chee-KiatHepatitis B Annual 2006 3(1):35-53
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Tan Chee-Kiat Source Type: journals
Hepatitis B virus genotypes: Epidemiology and therapeutic implications
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Liu Chun-Jen, Kao Jia-HorngHepatitis B Annual 2006 3(1):54-75
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Liu Chun-Jen, Kao Jia-Horng Source Type: journals
Management of chronic hepatitis B infection in patients with end-stage renal disease and dialysis
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Wong Ping-Nam, Mak Siu-Ka, Wong Andrew Kui-ManHepatitis B Annual 2006 3(1):76-105
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Wong Ping-Nam, Mak Siu-Ka, Wong Andrew Kui-Man Source Type: journals
Management of chronic hepatitis B in children
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Liberek Anna, Luczak Graeyna, Gora-Gebka Magdalena, Landowski PiotrHepatitis B Annual 2006 3(1):106-127
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Liberek Anna, Luczak Graeyna, Gora-Gebka Magdalena, Landowski Piotr Source Type: journals
Extrahepatic manifestations of chronic hepatitis B
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Shim Michael, Han Steven-Huy BHepatitis B Annual 2006 3(1):128-154
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Shim Michael, Han Steven-Huy B Source Type: journals
Management of hepatitis B viral infection with normal ALT
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Amarapurkar DeepakHepatitis B Annual 2006 3(1):155-164
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Amarapurkar Deepak Source Type: journals
Controversies in the management of hepatitis B
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Choudhuri Gourdas, Piramanayagam PHepatitis B Annual 2006 3(1):165-179
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - June 16, 2007 Category: Hematology Authors: Choudhuri Gourdas, Piramanayagam P Source Type: journals
Foreword
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Acharya Subrat KumarHepatitis B Annual 2005 2(1):7-8
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Acharya Subrat Kumar Source Type: journals
Hepatitis B viral infection: Emerging challenges
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Chawla YKHepatitis B Annual 2005 2(1):9-10
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Chawla YK Source Type: journals
Management of chronic hepatitis B infection: Miles to go.......
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Singh Shivaram PrasadHepatitis B Annual 2005 2(1):11-13
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Singh Shivaram Prasad Source Type: journals
Occult hepatitis B virus infection
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Allain Jean-PierreHepatitis B Annual 2005 2(1):14-30
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Allain Jean-Pierre Source Type: journals
Preventive and therapeutic approaches against hepatitis B virus by vaccine
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This article reviews the development of more potent prophylactic vaccines against HBV and better regimens of therapeutic vaccines for patients with chronic hepatitis B with special reference to the recent developments in the relevant fields.
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Akbar Sk. Md. Fazle, Onji Morikazu Source Type: journals
Hepatitis B immunization: Is a booster necessary?
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Lu Chun-Yi, Chang Mei-HweiHepatitis B Annual 2005 2(1):56-73
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Lu Chun-Yi, Chang Mei-Hwei Source Type: journals
HBV variants: Clinical significance and public health implications
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Revill Peter, Locarnini StephenHepatitis B Annual 2005 2(1):74-92Inadequate and/or inappropriate host immune responses, are mainly responsible for the liver disease of chronic hepatitis B. Infection of the hepatocyte with the hepatitis B virus (HBV) results in very high levels of viral replication without actually killing the infected cell directly. The HBV uses reverse transcription to copy its DNA genome and because of a lack of proof-reading capability, mutant viral genomes or quasi species, emerge continually. All the selection pressures, both endogenous (host immune clearance) and exogenous (vaccines and antiviral dru...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Revill Peter, Locarnini Stephen Source Type: journals
Comparison of lamividine and adefovir dipivoxil in the treatment of chronic hepatitis B
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Leung NancyHepatitis B Annual 2005 2(1):93-126Nucleot(s)ide analogues are making milestones in the treatment of chronic hepatitis B (CHB). Lamivudine was approved by FDA for the treatment of chronic hepatitis B in adult patients n 1998 (Zeffix<sup>TM</sup> Heptodin<sup>TM</sup> Heptovir<sup>TM</sup> Epivir-HBV<sup>TM</sup> Glaxo Wellcome). Adefovir dipivoxil was approved by FDA in 2002 (Hepsera, Gilead). Both were licensed and available in many countries. A comparis...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Leung Nancy Source Type: journals
Long-term management of patients with chronic hepatitis B virus infection
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Lok Anna SFHepatitis B Annual 2005 2(1):127-153
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Lok Anna SF Source Type: journals
Pathogenesis, prevention and treatment of hepatitis B associated hepatocellular carcinoma
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London W Thomas, Mason William S, Nguyen MinhhuyenHepatitis B Annual 2005 2(1):154-185
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: London W Thomas, Mason William S, Nguyen Minhhuyen Source Type: journals
The epidemiology of hepatitis B virus infection in healthcare workers in the West and Asia
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Alter Miriam JHepatitis B Annual 2005 2(1):186-192
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - February 5, 2007 Category: Hematology Authors: Alter Miriam J Source Type: journals
Foreword
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Blumberg Baruch SHepatitis B Annual 2004 1(1):5-6
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Blumberg Baruch S Source Type: journals
Editorial
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Singh Shivaram Prasad, Chawla Yogesh KumarHepatitis B Annual 2004 1(1):7-9
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Singh Shivaram Prasad, Chawla Yogesh Kumar Source Type: journals
From Australia antigen to eradication programs
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Blumberg Baruch SHepatitis B Annual 2004 1(1):10-16
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Blumberg Baruch S Source Type: journals
Epidemiology of hepatitis B virus infection in India
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Chowdhury AbhijitHepatitis B Annual 2004 1(1):17-24
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Chowdhury Abhijit Source Type: journals
Prophylaxis of viral hepatitis: A global perspective
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Chongsrisawat Voranush, Chatchatee Pantipa, Poovorawan YongHepatitis B Annual 2004 1(1):25-59
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Chongsrisawat Voranush, Chatchatee Pantipa, Poovorawan Yong Source Type: journals
Universal neonatal hepatitis B virus vaccination in India: Why?
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Aggarwal RakeshHepatitis B Annual 2004 1(1):60-71
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Aggarwal Rakesh Source Type: journals
Hepatitis B virus infection in children in India
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Sathiyasekaran Malathi, Sankaranarayanan VSHepatitis B Annual 2004 1(1):72-91
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Sathiyasekaran Malathi, Sankaranarayanan VS Source Type: journals
Histopathological scoring of chronic viral hepatitis
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Gupta S DattaHepatitis B Annual 2004 1(1):92-112
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Gupta S Datta Source Type: journals
Management of chronic hepatitis due to hepatitis B virus infection
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Acharya Subrat Kumar, Batra YogeshHepatitis B Annual 2004 1(1):113-139
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - October 20, 2006 Category: Hematology Authors: Acharya Subrat Kumar, Batra Yogesh Source Type: journals
