The American Journal of Cardiology
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Editorial Board
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Combined Role of Reduced Estimated Glomerular Filtration Rate and Microalbuminuria on the Prevalence of Peripheral Arterial Disease
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Chronic kidney disease (CKD), defined by either microalbuminuria (MA) or a reduced estimated glomerular filtration rate (eGFR), is associated with an increased risk of peripheral arterial disease (PAD). The presence of both abnormalities might identify a subgroup of adults at particularly high risk of PAD. Accordingly, we sought to evaluate the combined effect of a reduced eGFR and MA on the prevalence of PAD among United States adults. United States adults ≥40 years old (n = 6,951) participating in the 1999 to 2004 National Health and Nutrition Examination Survey were cross-classified into 4 groups according to the pres...
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: Usman Baber, Devin Mann, Daichi Shimbo, Mark Woodward, Jeffrey W. Olin, Paul Muntner Tags: Miscellaneous Source Type: journals
Distribution of Left Ventricular Ejection Fraction in Patients With Ischemic and Hypertensive Heart Disease and Chronic Heart Failure
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In conclusion, the observed bimodal distribution of EF in patients with chronic HF is a reflection of 2 HF phenotypes with different underlying pathophysiologic features. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: William H. Gaasch, Dennis E. Delorey, Fred J. Kueffer, Michael R. Zile Tags: Heart Failure Source Type: journals
Optimization of the Interventricular Delay in Cardiac Resynchronization Therapy Using the QRS Width
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Optimization of the interventricular pacing delay (VV) in cardiac resynchronization therapy is time-consuming and not routinely performed. The aim of the present study was to compare the acute hemodynamic response obtained by different VV programming methods. Several methods for optimizing the VV using electrocardiographic or echocardiographic measurements were performed. The effect of programming an empirical prefixed VV of 0 ms was also evaluated. Invasive first derivative of left ventricular (LV) pressure over time (dP/dt max) was measured at several VV values, and the hemodynamic response that could be obtained by each...
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: David Tamborero, Lluís Mont, Marta Sitges, Etelvino Silva, Antonio Berruezo, Barbara Vidal, Victoria Delgado, Jose M. Tolosana, Miguel Godoy, Angeles Castel, Josep Brugada Tags: Heart Failure Source Type: journals
Usefulness of Triglycerides-to–High-Density Lipoprotein Cholesterol Ratio for Predicting the First Coronary Event in Men
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In conclusion, the TG/HDL ratio has a high predictive value of a first coronary event regardless of BMI. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: Alberto Cordero, Eva Andrés, Beatriz Ordoñez, Montserrat León, Martín Laclaustra, Alberto Grima, Emilio Luengo, José Moreno, María Bes, Isaac Pascual, Fernando Civeira, Miguel Pocoví, Eduardo Alegría, José A. Casasnovas, MESYAS (MEtabolic Syndrom Tags: Preventive Cardiology Source Type: journals
Comparison of Dual Source Computed Tomography Versus Intravascular Ultrasound for Evaluation of Coronary Arteries at Least One Year After Cardiac Transplantation
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In conclusion, DSCT permits the investigation of transplant recipients concerning the presence of CAV with good image quality and high diagnostic accuracy. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: Tiziano Schepis, Stephan Achenbach, Michael Weyand, Philip Raum, Mohamed Marwan, Tobias Pflederer, Werner G. Daniel, Rene Tandler, Markus Kondruweit, Dieter Ropers Tags: Coronary Artery Disease Source Type: journals
Contents
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Editorial Board
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Correction
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There is a typographical error in the article, “Usefulness of Transcatheter Patent Foramen Ovale Closure in Migraineurs With Moderate to Large Right-to-Left Shunt and Instrumental Evidence of Cerebrovascular Damage,” which was published in the August 1, 2009 issue of the Journal. The third author's name is: (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Tags: Readers' Comments Source Type: journals
Reducing Cardiovascular Risks of Nonsteroidal Anti-Inflammatory Drugs by Using Topical Formulations
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Discussion of the cardiovascular risk implications of using topical agents to reduce systemic NSAID exposure would have been an interesting addition to this elaborate review and clinically relevant jointly to patients and clinicians who are using or considering the option of using topical NSAIDs. In my clinical practice, we have observed a paucity of systemic adverse events with topical diclofenac 1% gel. This formulation provides an additional opportunity for consideration for those patients with creatinine clearance (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Robert L. Barkin Tags: Readers' Comments Source Type: journals
Death and Dying in Heart Failure With Normal Ejection Fraction
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In conclusion, better characterization of patients with HFNEF at greatest risk for heart failure–related death and understanding the risks of the different modes of death would allow more effective use of specific heart failure medical or device therapy in patients with HFNEF. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Hoong Sern Lim, Roger Beadle, Michael Frenneaux Tags: Editorial Source Type: journals
Is Age Really a Non-Modifiable Cardiovascular Risk Factor?
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The occurrence of all clinical manifestations of atherosclerosis increases with age. Aging is also associated with the acquisition of and increments in major modifiable risk factors that contribute to development of cardiovascular disease (CVD). This cluster of CVD risk factors accompanying advancing age could account for much of the increase in CVD incidence as we age. However, multivariate analysis, adjusting for the accompanying burden of risk factors, indicates an independent contribution of age to the development of atherosclerotic CVD. This suggests that the aging process per se promotes atherosclerosis. Nevertheless...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: William B. Kannel, Ramachandran S. Vasan Tags: Editorial Source Type: journals
Frequency and Impact of Pulmonary Hypertension in Patients With Obstructive Sleep Apnea Syndrome
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The correlates and consequences of pulmonary hypertension (PH) associated with obstructive sleep apnea (OSA) are poorly understood. Patients undergoing pulmonary artery catheterization within 6 months of an overnight polysomnography showing OSA were included in the present analysis. A total of 83 patients with complete data were analyzed (no PH, n = 25 [30%]; PH, 58 [70%]; of these, 18 had a pulmonary capillary wedge pressure of (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Omar A. Minai, Basma Ricaurte, Roop Kaw, Jeff Hammel, Mary Mansour, Kevin McCarthy, Joseph A. Golish, James K. Stoller Tags: Miscellaneous Source Type: journals
Electrocardiographic Screening in Children With Attention-Deficit Hyperactivity Disorder
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Some investigators have suggested that children receiving stimulant medications to manage attention-deficit hyperactivity disorder should undergo screening electrocardiography to identify asymptomatic cardiac disease. However, no study to date has examined the efficacy and costs of this strategy. In the present study we sought to determine the utility of electrocardiographic screening in children with attention-deficit hyperactivity disorder. We reviewed the clinical experience of electrocardiographic screening of subjects with attention-deficit hyperactivity disorder (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: William T. Mahle, Camden Hebson, Margaret J. Strieper Tags: Miscellaneous Source Type: journals
A Comparison of Clopidogrel Responsiveness in Patients With Versus Without Chronic Renal Failure
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In conclusion, platelet responsiveness to clopidogrel decreased more in patients with chronic renal failure than in those with normal renal function, and this decreased platelet responsiveness to clopidogrel was not improved by an increase in the clopidogrel dosage. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Sang Hyun Park, Weon Kim, Chung Su Park, Won Yu Kang, Sun Ho Hwang, Wan Kim Tags: Miscellaneous Source Type: journals
Six-Month Follow-Up of Patients With In-Hospital Thrombocytopenia During Heparin-Based Anticoagulation (from the Complications After Thrombocytopenia Caused by Heparin [CATCH] Registry)
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In conclusion, the 6-month mortality rate among heparin-treated patients with thrombocytopenia is high, although the risk independently related to thrombocytopenia appears to be restricted to the acute hospital phase. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Renato D. Lopes, E. Magnus Ohman, Christopher B. Granger, Emily F. Honeycutt, Kevin J. Anstrom, Peter B. Berger, Eric M. Crespo, Gustavo B.F. Oliveira, Stephan Moll, David J. Moliterno, Charles S. Abrams, Richard C. Becker Tags: Miscellaneous Source Type: journals
Usefulness of Various Plasma Biomarkers for Diagnosis of Heart Failure in Children With Single Ventricle Physiology
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In conclusion, plasma B-type natriuretic peptide is a sensitive biomarker for clinical heart failure in young children with single-ventricle heart disease. The use of this plasma biomarker might facilitate detection of heart failure in these complex patients. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Amee Shah, Angela M. Feraco, Cynthia Harmon, Theresa Tacy, Jeffrey R. Fineman, Harold S. Bernstein Tags: Congenital Heart Disease Source Type: journals
Comparison of Impact of Prenatal Versus Postnatal Diagnosis of Congenitally Corrected Transposition of the Great Arteries
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In conclusion, CCTGA has a >70% risk of intervention in the first 3 years after birth. The outlook is guarded and has an important effect on prenatal counseling. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Andrea W. Wan, Alexandra Jevremovic, Elif Seda Selamet Tierney, Brian W. McCrindle, Elizabeth Dunn, Cedric Manlhiot, Rachel M. Wald, John P. Kingdom, Edgar T. Jaeggi, Lynne E. Nield Tags: Congenital Heart Disease Source Type: journals
Postnatal Angiographic Appearance of Left Ventricular Myocardium in Fetal Patients With Aortic Stenosis Having In-Utero Aortic Valvuloplasty
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In conclusion, patients after FAV have angiographically abnormal left ventricles, commonly involving extensive trabeculations of the free wall, but without septal involvement. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Babar Sultan Hasan, John Finbarr Keane, Wayne Tworetzky, James E. Lock, Audrey Chung Marshall Tags: Congenital Heart Disease Source Type: journals
Impact of Right Ventricular Dilation on Left Ventricular Myocardial Deformation in Patients After Surgical Repair of Tetralogy of Fallot
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In conclusion, the negative impact of RV dilation on LV function relates to its influence on LV circumferential strain and SR in patients after TOF repair. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Eddie W.Y. Cheung, Xue-cun Liang, Wendy W.M. Lam, Yiu-fai Cheung Tags: Congenital Heart Disease Source Type: journals
Effects of Bariatric Surgery on Inflammatory, Functional and Structural Markers of Coronary Atherosclerosis
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This study was designed to assess the effects of bariatric weight loss surgery on structural, functional, and inflammatory markers of coronary atherosclerosis. Obesity is a worldwide epidemic and an independent risk factor for coronary atherosclerosis. It remains unclear whether surgically induced weight loss reduces cardiovascular risk. This prospective study enrolled 50 consecutive subjects with morbid obesity who underwent Roux-en-Y gastric bypass surgery (GBS) after failed attempts at medical weight loss. Subjects were recruited through a comprehensive weight loss center affiliated with an academic tertiary care hospit...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Phillip Habib, John David Scrocco, Megan Terek, Vincent Vanek, J. Ronald Mikolich Tags: Preventive Cardiology Source Type: journals
Prognostic Accuracy of B-Natriuretic Peptide Measurements and Coronary Artery Calcium in Asymptomatic Subjects (from the Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research [EISNER] Study)
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B-type natriuretic peptide (BNP) has prognostic implications in patients with acute and chronic cardiac symptoms. Its prognostic role in asymptomatic patients with evidence of subclinical disease remains unclear. The population of this study included 2,458 asymptomatic adults (47% women) with an average Framingham risk score of 8.8 ± 7% who underwent computed tomographic evaluation of coronary artery calcium (CAC). BNP levels were measured using the Triage CardioProfilER panel method. Cox proportional-hazards models were used to estimate time to a cardiovascular (CV) event (n = 84; 16 deaths, 12 myocardial infarctions, 8 ...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Leslee J. Shaw, Donna M. Polk, Torry A. Kahute, Nathan D. Wong, Joanna Moon, Romalisa Miranda-Peats, Alan Rozanski, John D. Friedman, Sean Hayes, Louise Thomson, Daniel S. Berman Tags: Preventive Cardiology Source Type: journals
Predictors of Increased Radiation Dose During Percutaneous Coronary Intervention
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In conclusion, the present study has described factors that might contribute to an increased AK during PCI. In revealing a priori known factors associated with an increased radiation dose during PCI, physicians and patients might be more able to evaluate the risks and benefits of such a procedure. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Mathew Mercuri, Changchun Xie, Michael Levy, Nicholas Valettas, Madhu K. Natarajan Tags: Coronary Artery Disease Source Type: journals
Impact of Final Activated Clotting Time After Transradial Coronary Stenting With Maximal Antiplatelet Therapy
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In conclusion, with the combination of aspirin, clopidogrel pretreatment, and abciximab, a final ACT value of >330 seconds appears protective against peri-PCI myonecrosis, and this benefit was maintained for ≤3 years. With a transradial approach and maximal antiplatelet therapy, greater ACT values did not correlate with an increased risk of bleeding. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Olivier F. Bertrand, Josep Rodés-Cabau, Stéphane Rinfret, Éric Larose, Rodrigo Bagur, Guy Proulx, Onil Gleeton, Olivier Costerousse, Robert De Larochellière, Louis Roy Tags: Coronary Artery Disease Source Type: journals
Timing of Noncardiac Surgery After Coronary Artery Stenting With Bare Metal or Drug-Eluting Stents
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The current guidelines have recommended postponing noncardiac surgery (NCS) for ≥6 weeks after bare metal stent (BMS) placement and for ≥1 year after drug-eluting stent (DES) placement. However, much debate has ensued about these intervals. The aim of the present study was to assess the influence of different intervals between stenting and NCS and the use of dual antiplatelet therapy on the occurrence of perioperative major adverse cardiac events (MACEs). We identified 550 patients (376 with a DES and 174 with a BMS) by cross-matching the Erasmus Medical Center percutaneous coronary intervention (PCI) database with the...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Jan-Peter van Kuijk, Willem-Jan Flu, Olaf Schouten, Sanne E. Hoeks, Lisanne Schenkeveld, Peter P.T. de Jaegere, Jeroen J. Bax, Ron T. van Domburg, Patrick W. Serruys, Don Poldermans Tags: Coronary Artery Disease Source Type: journals
Comparison of Bivalirudin Monotherapy Versus Unfractionated Heparin Plus Tirofiban in Patients With Diabetes Mellitus Undergoing Elective Percutaneous Coronary Intervention
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In conclusion, in patients with diabetes mellitus undergoing elective percutaneous coronary intervention, the strategy of bivalirudin monotherapy compared to UFH plus routine tirofiban is safe and feasible and associated with a significant reduction of in-hospital bleeding. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Davide Tavano, Gabriella Visconti, Davide D'Andrea, Amelia Focaccio, Bruno Golia, Mariateresa Librera, Mario Caccavale, Bruno Ricciarelli, Carlo Briguori Tags: Coronary Artery Disease Source Type: journals
Serial Intravascular Ultrasound Analysis of Bifurcation Lesions Treated Using the Novel Self-Expanding Sideguard Side Branch Stent
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In conclusion, serial IVUS analyses of the self-expanding bare metal Sideguard stent indicate preserved SB ostial lumen dimensions at follow-up due to additional increases in stent area that more than compensated for IH. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Hiroshi Doi, Akiko Maehara, Gary S. Mintz, Lokesh Dani, Martin B. Leon, Eberhard Grube Tags: Coronary Artery Disease Source Type: journals
Relation of Troponin I Levels Following Nonemergent Percutaneous Coronary Intervention to Short- and Long-Term Outcomes
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In conclusion, an isolated increase in cTnI after nonemergent PCI is common, not associated with more frequent adverse in-hospital outcomes compared to patients with normal cTnI, and provides long-term prognostic information regarding mortality. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Dmitriy N. Feldman, Robert M. Minutello, Geoffrey Bergman, Issam Moussa, S. Chiu Wong Tags: Coronary Artery Disease Source Type: journals
Association of Door-to-Balloon Time and Mortality in Patients ≥65 Years With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
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Current guidelines recommend patients with ST-elevation myocardial infarction receive primary percutaneous coronary intervention (PCI) within 90 minutes of admission, although there are conflicting data regarding the relation between time to treatment and mortality in these patients. We used logistic regression analyses employing a fractional polynomial model to evaluate the association between door-to-balloon time and 1-year mortality in patients with ST-elevation myocardial infarction ≥65 years old undergoing primary PCI from 1994 to 1996 (n = 1,932). Median door-to-balloon time was 128 minutes (interquartile range 92 ...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Saif S. Rathore, Jeptha P. Curtis, Brahmajee K. Nallamothu, Yongfei Wang, JoAnne Micale Foody, Mikhail Kosiborod, Frederick A. Masoudi, Edward P. Havranek, Harlan M. Krumholz Tags: Coronary Artery Disease Source Type: journals
Screening for Depression and Suicidality in Patients With Cardiovascular Illnesses
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In conclusion, suicidal ideation can and will be identified using the AHA depression screening recommendations, but only a very small fraction (0.45%) of screened patients will turn out to have suicidal intent. Discovery and stabilization of suicidal patients is an important benefit of the screening, but the fact that >12% of all screened patients will need to be immediately evaluated for suicidal intent has important implications for resource allocation to screening programs. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Eyal Shemesh, Rachel A. Annunziato, David Rubinstein, Sarah Sultan, Jotinder Malhotra, Mugdha Santra, Beth D. Weatherley, John R. Feaganes, Gad Cotter, Rachel Yehuda Tags: Coronary Artery Disease Source Type: journals
Comparison Between Myocardial Contrast Echocardiography and 99mTechnetium Sestamibi Single Photon Emission Computed Tomography Determined Myocardial Viability in Predicting Hard Cardiac Events Following Acute Myocardial Infarction
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In conclusion, MV determined by MCE at rest was superior to nitrate-enhanced SPECT for the prediction of hard cardiac events after AMI. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Girish Dwivedi, Rajesh Janardhanan, Sajad A. Hayat, Tiong K. Lim, Roxy Senior Tags: Coronary Artery Disease Source Type: journals
Patient Characteristics Associated With the Choice of Triple Antithrombotic Therapy in Acute Coronary Syndromes
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Evidence regarding the use of dual antiplatelet therapy and oral anticoagulation (i.e., triple therapy) in acute coronary syndromes (ACS) is limited. We evaluated the characteristics associated with the choice of triple therapy in ACS. Using the Get With The Guidelines (GWTG) Coronary Artery Disease national registry, we studied patients with ACS at 361 sites in the United States from 2004 to 2007. Both univariate analysis and multivariate logistic regression analysis were used to assess the factors associated using triple therapy on discharge. The Generalized Estimating Equation method was used to account for within-hospi...
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Jeremiah P. Depta, Christopher P. Cannon, Gregg C. Fonarow, Xin Zhao, W. Frank Peacock, Deepak L. Bhatt, Get With The Guidelines Steering Committee and Investigators Tags: Coronary Artery Disease Source Type: journals
Contents
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Editorial Board
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(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Periodontitis, Atherosclerotic Cardiovascular Disease and Vitamin D
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The informative editors' consensus on periodontitis and cardiovascular disease did not mention vitamin D insufficiency as a likely mechanism for the association between the 2 diseases. We believe this is important, because maintaining adequate vitamin D levels might in part prevent these common maladies. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Mark R. Goldstein, Luca Mascitelli, Francesca Pezzetta Tags: Readers' Comments Source Type: journals
Assessment of Left Ventricular Dysfunction in Tako-Tsubo Cardiomyopathy
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We read with great interest the recent report of Chao et al concerning the diagnostic difficulties of tako-tsubo cardiomyopathy by left ventricular (LV) angiography. We agree that a blinded review of LV angiography may be difficult and may lead to misdiagnosis. However, biplane LV angiography could be of interest to avoid such a misdiagnosis. We recently demonstrated that systolic dysfunction in tako-tsubo cardiomyopathy during the acute phase is circular and is different from the LV systolic dysfunction observed in patients with left anterior descending coronary artery occlusion, suggesting that tako-tsubo cardiomyopathy ...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Nicolas Mansencal, Olivier Dubourg Tags: Readers' Comments Source Type: journals
Cardiac Resynchronization Therapy in Patients With Left Bundle Branch Block Versus Right Ventricular Pacing
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I read with interest the report by Delnoy et al in the July 1, 2009, issue of The American Journal of Cardiology regarding the long-term clinical and echocardiographic responses to cardiac resynchronization therapy (CRT) in 194 patients with left bundle branch block (LBBB) compared with 90 patients with LBBB-like electrocardiographic patterns due to right ventricular apical pacing (RVP). Although the patients in the 2 groups were different in certain characteristics at baseline (those with RVP had significantly greater ejection fractions and smaller left ventricular volumes), they responded equally well to CRT, showing sim...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: John E. Madias Tags: Readers' Comments Source Type: journals
Patent Foramen Ovale Closure and Migraines: Muddy Waters
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We read with interest the recent report by Papa et al, who reported a significant reduction in migraine severity after patent foramen ovale (PFO) closure in patients with significant baseline migraines. The findings challenge the Migraine Intervention With STARFlex Technology (MIST) study, which showed that PFO closure resulted in no overall benefit on migraine. An aspect of the study not discussed that needs clarification is whether there was alteration in antimigraine therapy after PFO closure. We recently reported that there is a rebound increase in migraine severity early ( (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Ravinay Bhindi, Oliver J. Ormerod Tags: Readers' Comments Source Type: journals
Propofol Infusion Syndrome With Arrhythmia, Myocardial Fat Accumulation and Cardiac Failure
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In conclusion, this cardiac fat accumulation illustrates the proposed underlying pathophysiology of impaired (muscular) free fatty acid utilization. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Philippe G. Jorens, Gert G. Van den Eynden Tags: Case Report Source Type: journals
Evaluation of the Effects of PM101, a Cyclodextrin-Based Formulation of Intravenous Amiodarone, on Blood Pressure in Healthy Humans
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In conclusion, the results of this study demonstrate that PM101 is devoid of hypotension in healthy human subjects. The absence of a hypotensive effect of AIV in this population suggests that further evaluation is needed in a patient population with cardiac disease. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Daniel J. Cushing, Michael P. Adams, Warren D. Cooper, Bing Zhang, Raymond J. Lipicky, Peter R. Kowey Tags: Cardiovascular Pharmacology Source Type: journals
Late Cardiovascular Complications After Surgical or Balloon Angioplasty of Coarctation of Aorta in an Asian Cohort
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In conclusion, the profile of reintervention for recoarctation and late systemic hypertension after CoA interventions in our Asian cohort with CoA was similar to that observed in white patients. Asian patients might have a lower risk of LVOTO. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Hsin-Hui Chiu, Shuenn-Nan Chiu, Fu-Chang Hu, Chun-An Chen, Ming-Tai Lin, Jou-Kou Wang, Chung-I. Chang, Yih-Shang Chen, Ing-Sh Chiu, Mei-Hwan Wu Tags: Congenital Heart Disease Source Type: journals
The Editor's Roundtable: Prehypertension
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This activity is supported by an educational grant from Bristol-Myers Squibb, New York, New York, and Sanofi-Aventis, Paris, France. Dr. Roberts has received honoraria for speaking from Merck & Company, Whitehouse Station, New Jersey; Schering-Plough, Kenilworth, New Jersey; AstraZeneca, Wilmington, Delaware; and Novartis, East Hanover, New Jersey. Dr. Bakris has received investigator-initiated grants from the National Institutes of Health, Bethesda, Maryland (National Institute of Diabetes and Digestive and Kidney Diseases and National Heart, Lung, and Blood Institute); GlaxoSmithKline, Research Triangle Park, North Caro...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: William C. Roberts, George L. Bakris, Henry R. Black, Domenic A. Sica, Destry J. Sulkes Tags: Roundtable Discussion (CME) Source Type: journals
Mitral E Wave Deceleration Time to Peak E Velocity Ratio and Cardiovascular Outcome in Hypertensive Patients During Antihypertensive Treatment (from the LIFE Echo-Substudy)
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We examined the utility of the MDI at baseline and as a time-varying predictor of incident CV events. Of the 770 patients, 70 (9%) had CV events. The baseline MDI was positively associated with age and relative wall thickness and negatively associated with gender and heart rate (all p (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Marcello Chinali, Gerard P. Aurigemma, Giovanni de Simone, Rakesh K. Mishra, Eva Gerdts, Kristian Wachtell, Kurt Boman, Björn Dahlöf, Richard B. Devereux Tags: Systemic Hypertension Source Type: journals
Prevalence, Functional Impact, and Mortality of Atrial Fibrillation in an Older Italian Population (from the Pro.V.A. Study)
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The prevalence of atrial fibrillation (AF) is increasing in older patients faster than that of any other arrhythmia. AF is associated with increased morbidity and mortality. Data on AF in European populations are scarce. The aim of this study was to determine the prevalence and potential predictors of AF and to assess its impact on physical function and mortality in a representative sample of an Italian population ≥65 years of age. One thousand five hundred ninety-nine participants in the Pro.V.A. study, an observational cohort study of Italian subjects ≥65 years old, were assessed for health status, disability, and pr...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Claudio Bilato, Maria-Chiara Corti, Giovannella Baggio, Debora Rampazzo, Ada Cutolo, Sabino Iliceto, Gaetano Crepaldi Tags: Arrhythmias and Conduction Disturbances Source Type: journals
Association of Electrocardiographic Abnormalities With Coronary Artery Calcium and Carotid Artery Intima–Media Thickness in Individuals Without Clinical Coronary Heart Disease (from the Multi-Ethnic Study of Atherosclerosis [MESA])
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In conclusion, ECG abnormalities are not associated with markers of subclinical atherosclerosis in a large multiethnic cohort. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Donald M. Lloyd-Jones, Joseph A. Walsh, Ronald J. Prineas, Hongyan Ning, Kiang Liu, Martha L. Daviglus, Steven Shea, Robert C. Detrano, Harikrishna Tandri, Philip Greenland Tags: Preventive Cardiology Source Type: journals
Predictive Values of Post-Treatment Adenosine Diphosphate–Induced Aggregation and Vasodilator-Stimulated Phosphoprotein Index for Stent Thrombosis After Acute Coronary Syndrome in Clopidogrel-Treated Patients
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In conclusion, in patients with non–ST-elevation acute coronary syndrome undergoing percutaneous coronary intervention, ADP-Ag is a good parameter to identify clopidogrel nonresponders who are at increased risk of stent thrombosis, with a cutoff value of ADP-Ag of >67%. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Thomas Cuisset, Corinne Frere, Jacques Quilici, Bénédicte Gaborit, Christel Castelli, Raphael Poyet, Laurent Bali, Pierre-Emmanuel Morange, Marie-Christine Alessi, Jean-Louis Bonnet Tags: Coronary Artery Disease Source Type: journals
Clinical Benefit of Early Reperfusion Therapy in Patients With ST-Elevation Myocardial Infarction Usually Excluded from Randomized Clinical Trials (Results from the Maximal Individual Therapy in Acute Myocardial Infarction Plus [MITRA Plus] Registry)
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Randomized clinical trials (RCTs) usually enroll selected patient populations that may not be representative for patients seen in everyday practice. Therefore, concerns have been raised regarding their external validity. For the present study we evaluated the MITRA Plus registry and included 20,175 patients with ST-elevation myocardial infarction. We defined RCT-ineligible patients as patients fulfilling ≥1 of the following criteria: age ≥75 years, prehospital delay >12 hours, prehospital cardiopulmonary resuscitation, cardiogenic shock, impaired renal function, and previous stroke. Those patients (n = 9,369, 46.4%) we...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Oliver Koeth, Ralf Zahn, Anselm Kai Gitt, Timm Bauer, Claus Juenger, Jochen Senges, Uwe Zeymer, Maximal Individual Therapy in Acute Myocardial Infarction Plus (MITRA Plus) Study Group Tags: Coronary Artery Disease Source Type: journals
Comparison of Prolonged Bivalirudin Infusion Versus Intraprocedural in Preventing Myocardial Damage After Percutaneous Coronary Intervention in Patients With Angina Pectoris
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In conclusion, in patients undergoing complex PCI, a prolonged bivalirudin infusion after PCI compared to an intraprocedural-only regimen significantly decreased the incidence of periprocedural myocardial damage. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Bernardo Cortese, Andrea Picchi, Andrea Micheli, Alberto Genovesi Ebert, Francesca Parri, Silva Severi, Ugo Limbruno Tags: Coronary Artery Disease Source Type: journals
Accuracy of Computed Tomographic Angiography for Stenosis Quantification Using Quantitative Coronary Angiography or Intravascular Ultrasound as the Gold Standard
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Computed tomographic angiography (CTA) is considered to have limited accuracy for quantifying exact percent diameter stenosis in coronary arteries. However, most studies evaluating CTA use quantitative coronary angiography (QCA) as the gold standard, a technique with its own limitations. We sought to determine whether CTA measurements of stenosis severity correlate better with intravascular ultrasound (IVUS) than with QCA. Luminal dimensions of 67 de novo coronary lesions were measured by CTA, IVUS, and QCA. IVUS was performed when lesion severity by angiography was equivocal. Mean percent diameter stenosis by QCA was 51 ...
Source: The American Journal of Cardiology - October 5, 2009 Category: Cardiology Authors: Subodh B. Joshi, Teruo Okabe, Robert O. Roswell, Gaby Weissman, Cristian F. Lopez, Joseph Lindsay, Augusto D. Pichard, Neil J. Weissman, Ron Waksman, Wm. Guy Weigold Tags: Coronary Artery Disease Source Type: journals
