Long COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort
To describe the experience of people with long COVID symptomatology and characterize the psychological, social, and financial challenges they experience. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2024 Category: General Medicine Authors: Mitsuaki Sawano, Yilun Wu, Rishi M. Shah, Tianna Zhou, Adith S. Arun, Pavan Khosla, Shayaan Kaleem, Anushree Vashist, Bornali Bhattacharjee, Qinglan Ding, Yuan Lu, C ésar Caraballo, Frederick Warner, Chenxi Huang, Jeph Herrin, David Putrino, Teresa Miche Source Type: research

Categorization of Patients with Pulmonary Embolism by Charlson Comorbidity Index
Pulmonary embolism is a cardiovascular life-threatening acute event afflicted by high morbidity and mortality.1-6 While the annual incidence of pulmonary embolism has increased in the past decades, the case fatality of this emergency event decreased in the same time.3,7-9 Mortality caused by pulmonary embolism is strongly and closely related to the patients ’ hemodynamic status and cardiac involvement, including right ventricular dysfunction and/or myocardial injury, as well as the patients’ comorbidity profile. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2024 Category: General Medicine Authors: Karsten Keller, Volker H. Schmitt, Omar Hahad, Christine Espinola-Klein, Thomas M ünzel, Philipp Lurz, Stavros Konstantinides, Lukas Hobohm Tags: Clinical Research Study Source Type: research

Looking Beyond LinkedIn: The Case for Excellence and Academic Rigor in Quality and Safety Programs
"...in life, you gotta keep showing up …until they give you those accolades you feel you deserve, until they call you chairman, until they call you a genius, until they call you the greatest of all time. You feel me? Thank you."-Jay Z, Grammy Awards, 2024 (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2024 Category: General Medicine Authors: Gonzalo Bearman, Priya Nori Tags: Commentary Source Type: research

Sociologic and Psychiatric Aspects of U.S. Gun Violence: A Cure For This Endemic
There are at least fifty million more guns in than people in America. The U.S. also suffers more shootings and ten times more gun deaths per-capita than any other developed country in the world1. Clearly the underlying problem is the widespread availability of weapons exclusively and efficiently designed to kill humans. These are the semi-automatic, double action handguns (E.G. Glock, Sig-Sauer, Beretta, etc.) used in homicides and suicides and the assault rifles used in mass shootings. However, upon forensic analysis virtually every event of gun violence (GV) routinely embodies societal and individual factors that made it...
Source: The American Journal of Medicine - April 23, 2024 Category: General Medicine Authors: James Webster Tags: Commentary Source Type: research

Overall medication adherence as an indicator for health outcomes among elderly patients with hypertension and diabetes
Various studies have demonstrated that medication adherence is a key factor in medical treatment. Stuart and colleagues found that good adherence to medication among diabetic patients was associated with lower medical costs1. In another study, Franchi and colleagues found that better adherence to treatment was associated with better health results2. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 23, 2024 Category: General Medicine Authors: Michal Shani, Alex Lustman, Doron Comaneshter, Yochai Schonmann Tags: Clinical Research Study Source Type: research

Inaccuracy of Initial Clinical Mobility Assessment in Venous Thromboembolism Risk Stratification
Venous thromboembolism risk increases in hospitals due to reduced patient mobility. However, initial mobility evaluations for thromboembolism risk are often subjective and lack standardization, potentially leading to inaccurate risk assessments and insufficient prevention. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Erik H Hoyer, Aditya Bhave, Wingel Xue, Elliott R. Haut, Brandyn D. Lau, Peggy Kraus, Alison E Turnbull, Dauryne Shaffer, Lisa Aronson Friedman, Daniel Young, Daniel J. Brotman, Michael B. Streiff Tags: Clinical Research Study Source Type: research

Factors Associated with Long COVID Recovery among US Adults
This study used national survey data to assess differences between adults in the United States with LC and those who recovered. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Kavya M. Shah, Rishi M. Shah, Mitsuaki Sawano, Yixuan Wu, Pamela Bishop, Akiko Iwasaki, Harlan M. Krumholz Tags: Brief Observation Source Type: research

A woman with trismus and fever
A 65-year-old woman presented with one week duration of fevers to 38 °C, 3 days of anterior neck pain, sore throat, and trismus. Physical examination showed tender masseter muscles bilaterally, with an inability to open her mouth past 1.5 finger breadths. (Figure 1A) Both temporal and carotid arteries were tender to palpation. Laboratory data showed an elevated C-re active protein level of 18.2 mg per deciliter, an erythrocyte sedimentation rate level of 110 mm per hour, and alanine and aspartate aminotransferase levels of 63 and 74 U/L per liter respectively. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Nozomi Tomikawa, Masaki Itagane, Mitsuyo Kinjo Tags: Clinical Communication to the Editor Source Type: research

Unravelling the Mechanisms Behind Exercise Intolerance and Recovery in Long COVID
This study investigated the relationship between heart rate recovery at the first minute (HRR1), a proxy for autonomic imbalance, and exercise intolerance in patients with long COVID. Additionally, the study aimed to assess the effects of a 12-week home-based inspiratory muscle training program on autonomic modulation in this patient population. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Patricia Palau, Beatriz Calvo, Clara Sastre, Eloy Dom ínguez, Paloma Marín, Cristina Flor, Julio Núñez, Laura López Source Type: research

Hemarthrosis in a patient with abdominal aortic aneurysm
To the Editor: (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Hiroyuki Tsurumi, Hiroyuki Yano, Mitsuyo Kinjo Tags: Clinical Communication to the Editor Source Type: research

Rhabdomyolysis due to Acute Alcohol Intoxication
A 27-year-old male was admitted with pain, swelling and weakness of bilateral lower limbs since 5 days associated with passage of high coloured urine and decreased urine output. He reported alcohol binge of country-made Indian whiskey (around 600 ml) a day prior to onset of symptoms. There was no history of trauma, drug intake or any form of physical exertion before onset of symptoms. He was managed at a local hospital with intravenous fluids before presentation to our institute. Physical examination showed stable vitals with bilateral lower limb tenderness, pitting edema up to calf region and restriction of movements in b...
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Dr Vishali Chandrasekhar, Dr Harpreet Singh, Dr Aravind Subramanian, Dr Deba Prasad Dhibhar, Dr Vikas Suri, Dr Ashish Bhalla Tags: Clinical Communication to the Editor Source Type: research

Pseudomonas aeruginosa bacteremia, pulmonary septic embolism, and reversed halo sign
To the Editor (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 20, 2024 Category: General Medicine Authors: Yoshinori Tateishi Tags: Clinical Communication to the Editor Source Type: research

Varicella-zoster virus vasculopathy: the importance of skin findings in assessing altered mental status
A previously healthy, 85-year-old, female patient presented with a ten-day history of progressive change in mental status. A physical examination revealed erythematous papules in a thoracic, dermatomal distribution (Figure 1A). Precise neurological assessment was difficult. Cerebrospinal fluid analysis revealed mild pleocytosis and elevated protein concentration. A polymerase chain reaction test (PCR) in the cerebrospinal fluid returned positive for varicella-zoster virus (VZV) DNA. The patient's HIV test result was negative. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 19, 2024 Category: General Medicine Authors: Yasuhiro Kano, Junko Araki Tags: Clinical Communication to the Editor Source Type: research

Comparative effectiveness and safety of ticagrelor and clopidogrel in patients with or without chronic liver disease: a nationwide cohort study
Although the effectiveness and safety of ticagrelor versus clopidogrel may differ in patients with chronic liver disease, there is a scarcity of evidence comparing ticagrelor and clopidogrel in patients with chronic liver disease. We aimed to evaluate the risk of major adverse cardiovascular events (MACE) and major bleeding associated with ticagrelor versus clopidogrel in patients undergoing percutaneous coronary intervention (PCI) due to acute coronary syndrome by chronic liver disease status. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 17, 2024 Category: General Medicine Authors: Bin Hong, Sungho Bea, Seng Chan You, Yoosoo Chang, Won Kim, Ju-Young Shin Tags: Clinical Research Study Source Type: research

Health Systems Science Integration in Graduate Medical Education: A Pathway to Quintuple Aim Success for Independent Practice
The United States continues to outspend other high-income countries on health care without improving health outcomes.1 This understanding has been a launching pad for changes to health care structure and processes and movement towards achieving the Institution of Healthcare Improvement (IHI) Quintuple Aim.2 While health systems evolve in the approaches to health care delivery, education on these fundamental skills for the professional medical community has lagged. The American Medical Association (AMA) instituted health systems science (HSS) in 2013 as a third pillar of medical education, bringing national attention to the...
Source: The American Journal of Medicine - April 11, 2024 Category: General Medicine Authors: Sonia Bharel, Brian McGillen, Rachel Salas, Dharmini Shah Pandya Tags: AAIM Perspectives Source Type: research