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(Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Tags: Society News and Announcements Source Type: research

Biologic Treatments for Sports Injuries II Think Tank--Current Concepts, Future Research, and Barriers to Advancement, Part 1: Biologics Overview, Ligament Injury, Tendinopathy
Biologic therapies, including stem cells, platelet-rich plasma, growth factors, and other biologically active adjuncts, have recently received increased attention in the basic science and clinical literature. At the 2015 AOSSM Biologics II Think Tank held in Colorado Springs, Colorado, a group of orthopaedic surgeons, basic scientists, veterinarians, and other investigators gathered to review the state of the science for biologics and barriers to implementation of biologics for the treatment of sports medicine injuries. This series of current concepts reviews reports the summary of the scientific presentations, roundtable ...
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: LaPrade, R. F., Geeslin, A. G., Murray, I. R., Musahl, V., Zlotnicki, J. P., Petrigliano, F., Mann, B. J. Tags: Shoulder, rotator cuff, Growth factors/Healing enhancement, Stem cell therapy, Knee, articular cartilage, Biologic healing enhancement, Tendinosis Current Concepts Source Type: research

Is There a Genetic Predisposition to Anterior Cruciate Ligament Tear? A Systematic Review
Conclusion: Although specific gene polymorphisms and haplotypes have been identified, it is difficult to come to a conclusion on the basis of the existing literature. Several sources of bias have been identified in these studies, and the results cannot be extrapolated to the general population. More studies are needed in larger populations of different ethnicities. Gene-gene interactions and gene expression studies in the future may delineate the exact role of these gene polymorphisms in ACL tears. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: John, R., Dhillon, M. S., Sharma, S., Prabhakar, S., Bhandari, M. Tags: Knee ligaments, ACL Current Concepts Source Type: research

The Combined Use of Losartan and Muscle-Derived Stem Cells Significantly Improves the Functional Recovery of Muscle in a Young Mouse Model of Contusion Injuries
Conclusion: When compared with MDSCs alone, the simultaneous treatment of muscle contusions with MDSCs and losartan significantly reduced scar formation, increased the number of regenerating myofibers, and improved the functional recovery of muscle; these effects were caused, at least in part, by the losartan-mediated upregulation of Smad7 and MyoD. Increased levels of Smad7 and MyoD together reduced the deposition of scar tissue (via the inhibition of TGF-β1 by Smad7) and committed the transplanted MDSCs toward a myogenic lineage (via Smad7-regulated MyoD expression). Clinical Relevance: The study findings contribut...
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Kobayashi, M., Ota, S., Terada, S., Kawakami, Y., Otsuka, T., Fu, F. H., Huard, J. Tags: Cell/Molecular biology, Growth factors/Healing enhancement, Muscle physiology, Stem cell therapy, Muscle injuries Biology and Translational Research Source Type: research

Multiple Past Concussions in High School Football Players: Are There Differences in Cognitive Functioning and Symptom Reporting?
Conclusion: In the largest study to date, high school football players with multiple past concussions performed the same on cognitive testing as those with no prior concussions. Concussion history was one of several factors that were independently related to symptom reporting. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Brooks, B. L., Mannix, R., Maxwell, B., Zafonte, R., Berkner, P. D., Iverson, G. L. Tags: Head injuries/concussion, Pediatric sports medicine, Football (American) Head Injury and Concussion Source Type: research

Time Trends in Incidence and Severity of Injury Among Collegiate Soccer Players in the United States: NCAA Injury Surveillance System, 1990-1996 and 2004-2009
Conclusion: These surveillance data show decreasing trends in collegiate soccer injuries. Whether these decreases are attributable to greater resources being allocated toward athlete health, injury management, or the safety of the playing environment cannot be determined. Given the prominence of soccer play in the United States, public health efforts should promote the use of this surveillance system to better inform and evaluate injury prevention practices and policies directed toward player safety. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Chandran, A., Barron, M. J., Westerman, B. J., DiPietro, L. Tags: Epidemiology, Injury prevention, Statistics, Football (Soccer) Epidemiology and Injury Prevention Source Type: research

Increasing Lower Extremity Injury Rates Across the 2009-2010 to 2014-2015 Seasons of National Collegiate Athletic Association Football: An Unintended Consequence of the "Targeting" Rule Used to Prevent Concussions?
Conclusion: The lower extremity injury rate has increased in NCAA football athletes. Similarly, SRC rates have increased, although this may be caused by concurrent policies related to better education, identification, and management. Targeting rule changes may be contributing to increased rates of player contact–related ankle injuries. Alongside continued surveillance research to examine longitudinal time trends, more in-depth individual-level examinations of how targeting rule changes influence coaching and player behaviors are warranted. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Westermann, R. W., Kerr, Z. Y., Wehr, P., Amendola, A. Tags: Head injuries/concussion, Epidemiology, Knee, general, Ankle, General sports trauma, Football (American) Epidemiology and Injury Prevention Source Type: research

Critical Findings on Magnetic Resonance Arthrograms in Posterior Shoulder Instability Compared With an Age-Matched Controlled Cohort
Conclusion: The presence of increased glenoid retroversion, glenoid dysplasia, and increased posterior capsular area on MRA are significantly associated with posterior labral tears and symptomatic posterior shoulder instability. Identification of these critical radiographic variables on magnetic resonance arthrography assists in the accurate diagnosis and management of clinically significant posterior shoulder instability. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Galvin, J. W., Parada, S. A., Li, X., Eichinger, J. K. Tags: Shoulder, instability, Shoulder, glenoid labrum, Imaging, magnetic resonance Source Type: research

Clinical and Ultrasonographic Evaluations of the Shoulders of Elite Swimmers
Conclusion: We found a high prevalence of rotator cuff and biceps tendinopathy, which was associated with increased symptoms. Tendinosis was also more common in swimmers with a positive sulcus sign, suggesting a role for shoulder laxity. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Rodeo, S. A., Nguyen, J. T., Cavanaugh, J. T., Patel, Y., Adler, R. S. Tags: Shoulder, instability, Swimming, Shoulder, rotator cuff, Tendinosis Source Type: research

Survivorship and Patient-Reported Outcomes After Comprehensive Arthroscopic Management of Glenohumeral Osteoarthritis: Minimum 5-Year Follow-up
Conclusion: This study demonstrates significant improvements in midterm clinical outcomes and high patient satisfaction after the arthroscopic CAM procedure for GHOA, with a 76.9% survivorship rate at a minimum of 5 years postoperatively. For patients looking for an alternative to TSA, the CAM procedure can provide reasonable outcomes and should be considered an effective procedure in appropriately selected, young active patients. Further studies are warranted to evaluate long-term outcomes and durability after this procedure. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Mitchell, J. J., Horan, M. P., Greenspoon, J. A., Menge, T. J., Tahal, D. S., Millett, P. J. Tags: Shoulder, replacement, Shoulder, general Source Type: research

Arthroscopic Bankart Repair Versus Open Bristow-Latarjet for Shoulder Instability: A Matched-Pair Multicenter Study Focused on Return to Sport
Conclusion: Arthroscopic stabilization using anchors provided better return to sport and subjective perception of the shoulder compared with the open Bristow-Latarjet procedure in the population studied. Recurrence may be higher in the arthroscopic Bankart group; further study is needed on this point. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Blonna, D., Bellato, E., Caranzano, F., Assom, M., Rossi, R., Castoldi, F. Tags: Shoulder, instability, Clinical assessment/Grading scales Source Type: research

Outcomes After Arthroscopic Pancapsular Capsulorrhaphy With Suture Anchors for the Treatment of Multidirectional Glenohumeral Instability in Athletes
Conclusion: APC with suture anchors can be an effective and safe treatment for patients with MDI. Labral tears were commonly found, even in patients with a classic, atraumatic onset. Male patients and patients with a traumatic onset of MDI had more favorable outcomes. Female patients may be more challenging to treat as they were more likely to undergo an additional RIC procedure and experience postoperative subluxations. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Raynor, M. B., Horan, M. P., Greenspoon, J. A., Katthagen, J. C., Millett, P. J. Tags: Shoulder, instability Source Type: research

Factors Related to Increased Ulnar Collateral Ligament Thickness on Stress Sonography of the Elbow in Asymptomatic Youth and Adolescent Baseball Pitchers
Conclusion: These findings suggest that UCL thickness increases as pitchers get older and heavier and as they increase their pitch volumes. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Atanda, A., Averill, L. W., Wallace, M., Niiler, T. A., Nazarian, L. N., Ciccotti, M. G. Tags: Anatomy, Elbow, Imaging, diagnostic ultrasound, Baseball/Softball Source Type: research

Results of Bone Peg Grafting for Capitellar Osteochondritis Dissecans in Adolescent Baseball Players
Conclusion: BPG enabled 91% of COCD patients with ICRS OCD I or II to return to preoperative baseball abilities within 12 months. Integration of the grafted site may continue until at least 24 months postoperatively. An ICRS OCD I or II lesion with central positioning and/or occupying <75% of the size of the capitellum in the coronal plane is a good indication for BPG. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Oshiba, H., Itsubo, T., Ikegami, S., Nakamura, K., Uchiyama, S., Kato, H. Tags: Elbow, Pediatric sports medicine, Baseball/Softball Source Type: research

Performance and Injury Characteristics of Pitchers Entering the Major League Baseball Draft After Ulnar Collateral Ligament Reconstruction
Conclusion: There was no difference in the rate of professional advancement among pitchers drafted by the MLB who had undergone UCLR as amateurs compared with controls. Both groups had similar statistical performance. Pitchers in the UCLR group had an increased risk of DL assignment but no increase in the number of days on DL or risk of DL placement for elbow injury. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - November 29, 2016 Category: Sports Medicine Authors: Wymore, L., Chin, P., Geary, C., Carolan, G., Keefe, D., Hoenecke, H., Fronek, J. Tags: Elbow, Baseball/Softball Source Type: research