Over 25 Years of Hope: Development of Lymphatic Filariasis Patient Support Groups in Haiti
Am J Trop Med Hyg. 2024 Apr 23:tpmd230607. doi: 10.4269/ajtmh.23-0607. Online ahead of print.ABSTRACTSupport groups can create environments that are conducive to healing and well-being, particularly for persons with stigmatizing chronic diseases. In 1998, the support group concept was adapted in Haiti for persons with disabling lymphedema caused by lymphatic filariasis (LF). The project was developed with the expectation that the support group model conceived in the developed world be interpreted and modified by persons affected with lymphedema in the Haitian setting. Initiated with modest financial support within a resear...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Valery Madsen Beau De Rochars Jeannine Coreil Martha D ésir Gladys Mayard Marie Carmel Michel Marie Denise Milord Rand Carpenter Thomas G Streit Lucc ène Désir Gregory S Noland David G Addiss Source Type: research

Surveillance for Action: Operationalizing Private Sector Surveillance and Service Delivery across the Malaria Transmission Continuum
Am J Trop Med Hyg. 2024 Apr 23:tpmd230447. doi: 10.4269/ajtmh.23-0447. Online ahead of print.ABSTRACTDespite global recommendations that surveillance systems should capture malaria case data from both private and public sectors, the integration of private sector data into national systems remains a challenge for national malaria programs in high-burden settings. The WHO's Malaria Surveillance, Monitoring & Evaluation: A Reference Manual suggests eight general guidelines for conducting private sector surveillance. Practical operational guidance is needed to implement private sector surveillance and service delivery inte...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Erica Berlin Christopher Louren ço Stephen Poyer Source Type: research

Case Report: Obstetric and COVID-19-Related Morbidity and Mortality in Three Patients with Sickle Hemoglobinopathy
We describe the maternal and neonatal outcomes of three patients with COVID-19 and SCD (including two with hemoglobin SC disease and one with hemoglobin SS disease), with complications including the demise of a mother and a newborn. Vaso-occlusive crisis was the more common presentation. Two patients required ventilatory support. Although previous reports have shown similar clinical sequelae in pregnant and nonpregnant patients with SCD and COVID-19, maternal and neonatal deaths remain possible.PMID:38653217 | DOI:10.4269/ajtmh.23-0761 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Shanea Gibson Tiffany Hunter Nadine Johnson Source Type: research

Farmworker Mobility and COVID-19 Vaccination Strategies: Yuma County, Arizona, 2021
Am J Trop Med Hyg. 2024 Apr 23:tpmd220789. doi: 10.4269/ajtmh.22-0789. Online ahead of print.ABSTRACTFarmworkers, a group of essential workers, experience a disproportionately high burden of COVID-19 due to their living and working conditions. This project characterized farmworker mobility in and around Yuma County, Arizona, to identify opportunities to improve farmworker access to COVID-19 vaccination. We collected qualitative and geospatial data through a series of in-person and virtual focus group discussions, key informant interviews, and intercept interviews with participatory mapping. Participants included farmworker...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Katherine A Franc Alba E Phippard Priscila Ruedas Sarah J Pinto Kanan Mehta Sonia Montiel Sonia Contreras Hannah Katz Elvira McIntyre Benito Lopez Michelle Kreutzberg-Martinez Daisy Steiner Diana Gomez Rebecca Merrill Source Type: research

African Green Monkeys Maintain Zika Virus Neutralizing Antibodies for at Least 1,427 Days Postinfection
We report strong Zika virus (ZIKV) neutralizing antibody responses in African green monkeys (Chlorocebus sabaeus) up to 1,427 days after ZIKV exposure via the subcutaneous, intravaginal, or intrarectal routes. Our results suggest that immunocompetent African green monkeys previously infected with ZIKV are likely protected from reinfection for years, possibly life, and would not contribute to virus amplification during ZIKV epizootics.PMID:38653230 | DOI:10.4269/ajtmh.23-0521 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Andrew D Haddow Stephanie V Trefry Farooq Nasar Joshua D Shamblin M Louise M Pitt Source Type: research

Increased Prevalence of Antibodies to Hepatitis E Virus in Patients with Neurocysticercosis
Am J Trop Med Hyg. 2024 Apr 23:tpmd230856. doi: 10.4269/ajtmh.23-0856. Online ahead of print.ABSTRACTWe explored the association between serological status for hepatitis E and neurocysticercosis (NCC) in neurologic patients attending a national neurological referral center in Lima, Perú, between the years 2008 and 2012. Anti-hepatitis E antibodies were evaluated in patients with and without NCC, and a control group of rural general population. Anti-hepatitis E IgG was found in 23.8% of patients with NCC, compared with 14.3% in subjects without NCC from a general rural population (P = 0.023) and 14.4% in subjects with neur...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Jesus Abanto Arantxa N Sanchez Boluarte Yesenia Castillo Erika Perez Herbert Saavedra Isidro Gonzales Javier A Bustos Florence Abravanel Jacques Izopet Richie G Madden Hector H Garcia Harry R Dalton Source Type: research

Mycobacterium tuberculosis Infection in School Contacts of Tuberculosis Cases: A Systematic Review and Meta-Analysis
Am J Trop Med Hyg. 2024 Apr 23:tpmd230038. doi: 10.4269/ajtmh.23-0038. Online ahead of print.ABSTRACTSubstantial tuberculosis transmission occurs outside of households, and tuberculosis surveillance in schools has recently been proposed. However, the yield of tuberculosis outcomes from school contacts is not well characterized. We assessed the prevalence of Mycobacterium tuberculosis infection among close school contacts by performing a systematic review. We searched PubMed, Elsevier, China National Knowledge Infrastructure, and Wanfang databases. Studies reporting the number of children who were tested overall and who tes...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Wenjin Wang Aohan Liu Xinjie Liu Nannan You Zhan Wang Cheng Chen Limei Zhu Leonardo Martinez Wei Lu Qiao Liu Source Type: research

The Walter Reed Project, Kisumu Field Station: Impact of Research on Malaria Policy, Management, and Prevention
Am J Trop Med Hyg. 2024 Apr 23:tpmd230115. doi: 10.4269/ajtmh.23-0115. Online ahead of print.ABSTRACTThe Walter Reed Project is a collaboration between the Walter Reed Army Institute of Research of the United States Department of Defense and the Kenya Medical Research Institute. The Kisumu field station, comprising four campuses, has until recently been devoted primarily to research on malaria countermeasures. The Kombewa Clinical Research Center is dedicated to conducting regulated clinical trials of therapeutic and vaccine candidates in development. The center's robust population-based surveillance platform, along with a...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Peter M Sifuna Michal Mbinji Tina O Lucas Irene Onyango Hoseah M Akala John N Waitumbi Bernhards R Ogutu Jack N Hutter Walter Otieno Source Type: research

Associations between Antenatal Care Visit Attendance and Infant Mortality and Growth
This study examines the association between antenatal care (ANC) attendance and infant mortality and growth outcomes. The study used data from the Nouveux-nés et Azithromycine: une Innovation dans le Traitement des Enfants (NAITRE) trial conducted in Burkina Faso. This analysis included 21,795 neonates aged 8 to 27 days who were enrolled in the trial and had ANC data available. Infants were followed until 6 months of age. The analysis adjusted for potential confounders including infant's sex, maternal age, education, urbanicity, geographic region, season (dry versus rainy), pregnancy type (singleton versus multiple), numb...
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Aimee J Lansdale Mamadou Bountogo Ali Sie Alphonse Zakane Guillaume Compaor é Thierry Ouedraogo Elodie Lebas Thomas Lietman Catherine E Oldenburg Source Type: research

Prevalence and Characteristics of Plasmodium vivax Gametocytes in Duffy-Positive and Duffy-Negative Populations across Ethiopia
This study highlights the presence of P. vivax gametocytes in Duffy-negative infections, suggestive of human-to-mosquito transmissibility. Although P. vivax infections in Duffy-negative individuals were commonly associated with low parasitemia, some of these infections were shown to have relatively high parasitemia and may represent a prominent erythrocyte invasion capability of P. vivax, and hidden reservoirs that can contribute to transmission. A better understanding of P. vivax transmission biology and gametocyte function particularly in Duffy-negative populations would aid future treatment and management of P. vivax ma...
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Ebony Little Tassew T Shenkutie Meshesha Tsigie Negash Beka R Abagero Abnet Abebe Jean Popovici Sindew Mekasha Feleke Eugenia Lo Source Type: research

Effect of Non-Rotavirus Enteric Infections on Vaccine Efficacy in a ROTASIIL Clinical Trial
This study examined the relative proportion of enteric pathogens associated with severe gastroenteritis (GE) among children younger than 2 years in a phase III efficacy trial of the ROTASIIL® vaccine in India, evaluated the impact of co-infections on vaccine efficacy (VE), and characterized the association between specific pathogens and the clinical profile of severe GE. Stored stool samples collected from cases of severe GE in the phase III trial were tested by quantitative polymerase chain reaction using TaqMan™ Array Cards. Etiology was attributed by calculating the adjusted attributable fraction (AF) for each pathog...
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Dilip Abraham Prasanna Samuel Premkumar James A Platts-Mills Tushar Tewari Niranjan Bhat Revathi Rajendiran Hemavathi Gunalan Gagandeep Kang Source Type: research

Case Report: Mixed Airborne Contact Dermatitis-Chronic Actinic Dermatitis Pattern of Parthenium Dermatitis with Response to Tofacitinib Therapy
We report a patient with a chronic and extensive mixed ABCD-CAD pattern of parthenium dermatitis recalcitrant to conventional treatment, with rapid resolution after initiation of treatment with tofacitinib.PMID:38626752 | DOI:10.4269/ajtmh.23-0720 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Ananta Khurana Sheetal Yadav Kunal Chanana Kabir Sardana Aakash Vidholiya Source Type: research

Hourglass Sign in Liver Hydatid Disease: Significance and Therapeutic Implications
Am J Trop Med Hyg. 2024 Apr 16:tpmd230722. doi: 10.4269/ajtmh.23-0722. Online ahead of print.NO ABSTRACTPMID:38626759 | DOI:10.4269/ajtmh.23-0722 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Anis Hasnaoui Racem Trigui Firas Attig Source Type: research

Associations between Antenatal Care Visit Attendance and Infant Mortality and Growth
This study examines the association between antenatal care (ANC) attendance and infant mortality and growth outcomes. The study used data from the Nouveux-nés et Azithromycine: une Innovation dans le Traitement des Enfants (NAITRE) trial conducted in Burkina Faso. This analysis included 21,795 neonates aged 8 to 27 days who were enrolled in the trial and had ANC data available. Infants were followed until 6 months of age. The analysis adjusted for potential confounders including infant's sex, maternal age, education, urbanicity, geographic region, season (dry versus rainy), pregnancy type (singleton versus multiple), numb...
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Aimee J Lansdale Mamadou Bountogo Ali Sie Alphonse Zakane Guillaume Compaor é Thierry Ouedraogo Elodie Lebas Thomas Lietman Catherine E Oldenburg Source Type: research

Prevalence and Characteristics of Plasmodium vivax Gametocytes in Duffy-Positive and Duffy-Negative Populations across Ethiopia
This study highlights the presence of P. vivax gametocytes in Duffy-negative infections, suggestive of human-to-mosquito transmissibility. Although P. vivax infections in Duffy-negative individuals were commonly associated with low parasitemia, some of these infections were shown to have relatively high parasitemia and may represent a prominent erythrocyte invasion capability of P. vivax, and hidden reservoirs that can contribute to transmission. A better understanding of P. vivax transmission biology and gametocyte function particularly in Duffy-negative populations would aid future treatment and management of P. vivax ma...
Source: The American Journal of Tropical Medicine and Hygiene - April 16, 2024 Category: Tropical Medicine Authors: Ebony Little Tassew T Shenkutie Meshesha Tsigie Negash Beka R Abagero Abnet Abebe Jean Popovici Sindew Mekasha Feleke Eugenia Lo Source Type: research