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Congenital melanocytic naevi.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Congenital melanocytic naevi, consisting of clusters of naevo-melanocytes, develop in utero. Although many congenital naevi are visible at birth, some may not become evident until later in life. The timing of naevo-melanocyte proliferation, senescence and melanogenesis may all contribute towards determining when a naevus will become clinically manifest on the skin. Besides the fact that congenital melanocytic naevi may be aesthetically displeasing, resulting in a multitude of psychosocial issues, they also increase the risk for developing cutaneous melanoma, leptomeningeal melanoma, neurocutaneous melanocytosis, malfor...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Kovalyshyn I, Braun R, Marghoob A Tags: Australas J Dermatol Source Type: journals

Paediatric vulval lichen sclerosus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lichen sclerosus (LS) in children is uncommon; however, it is an important differential diagnosis in any pre-pubertal child presenting with chronic vulval symptoms. The long-term prognosis is unknown; however, recent data suggests that the assumption that the condition will resolve at puberty may be incorrect. Children with LS require long-term management with topical corticosteroids, which remains the treatment of choice, as well as long-term follow up. We review the current literature on paediatric vulval LS. PMID: 19916966 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Smith SD, Fischer G Tags: Australas J Dermatol Source Type: journals

Role of definitive radiotherapy in treating patients with inoperable Merkel cell carcinoma: the Westmead Hospital experience and a review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the results of eight patients with inoperable MCC treated with RTx alone between 1993 and 2007 at Westmead Hospital, Sydney, Australia, and also review the relevant literature on definitive RTx in the treatment of MCC. The median age at diagnosis was 82.5 years in five women and three men. All patients were Caucasian and none were immunosuppressed. Seven of eight patients were clinically node-positive. The mean duration of follow up was 12 months. A median dose of 50 Gy was prescribed. Seven of eight patients with inoperable MCC achieved in-field control, with most eventually relapsing distantly. Treatment-relate...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Koh CS, Veness MJ Tags: Australas J Dermatol Source Type: journals

Melanoma in private practice: do dermatologists make a difference?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malignant melanoma is a major contributor to Australian morbidity and mortality. In this era of resource rationalisation, we seek to address the issue of whether routine full-skin examination by a dermatologist, rather than focussed examination of flagged lesions, will increase melanoma diagnosis. A retrospective chart review was undertaken between 1 July 2007 and 30 June 2008 in a private dermatology group practice in order to ascertain the number and characteristics of incidentally detected melanomas on routine skin examination. A total of 94 melanomas were detected during this 12-month period. Of these, 57 (60.6%) w...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Cherian P, Tait CP Tags: Australas J Dermatol Source Type: journals

Cutaneous invasive squamous cell carcinoma: 10-year experience and recommendations for follow up.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Currently, the National Health and Medical Research Council do not have any recommendations about the frequency of follow up after treatment of primary cutaneous invasive squamous cell cancer (SCC), due to a lack of data. The present study aimed to establish appropriate follow-up times and to determine the long-term risk of subsequent non-melanoma skin cancers and melanoma. Patients who had a primary invasive cutaneous SCC excised during 1996 were retrospectively identified from the databases of a dermatologist in private practice in south-east Queensland. Data on size, site, depth, differentiation, perineural involvem...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Yoong C, De'Ambrosis B Tags: Australas J Dermatol Source Type: journals

Topical diphencyprone immunotherapy for cutaneous metastatic melanoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatmen...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Damian DL, Shannon KF, Saw RP, Thompson JF Tags: Australas J Dermatol Source Type: journals

Childhood ocular rosacea: considerations for diagnosis and treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report three cases of paediatric ocular rosacea responding to prolonged treatment with oral erythromycin. Our cases demonstrate the close association of periorificial dermatitis with childhood rosacea, and highlight the importance of eye signs in its diagnostic criteria. PMID: 19916971 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Hong E, Fischer G Tags: Australas J Dermatol Source Type: journals

Chronic localized intravascular coagulation complicating multifocal venous malformations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present two female children aged 7 years with extensive multifocal venous malformations complicated by chronic localized intravascular coagulation. In both cases ultrasonography and magnetic resonance imaging revealed extensive venous malformations involving the skin, mucous membranes and pharynx, which were not apparent on clinical examination. Haematological investigations demonstrated persistent elevation of the D-dimer, consistent with chronic localized intravascular coagulation. The course of one patient was complicated by the development of multiple painful thromboses at distant sites following percutaneous sclero...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Martin LK, Russell S, Wargon O Tags: Australas J Dermatol Source Type: journals

Diagnosis of type I cryoglobulinaemia made through identifying crystals in the blood smear.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of type I cryoglobulinaemia in a 52-year-old man who presented with widespread cutaneous necrosis. The diagnosis could not be established early on, as repeated testing for cryoglobulin was negative despite a careful collection method. The diagnosis was made 1 year later, on an incidental full blood smear that revealed crystals, which is an uncommon way to diagnose this condition. We discuss the difficulties we faced in establishing the diagnosis and emphasise the need for repeat cryoglobulin testing in this clinical setting. In such cases, examination of a blood smear should be considered. PMID: 199169...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Shirato K, Reid C, Ibbetson JS, Hissaria P, Shireen S Tags: Australas J Dermatol Source Type: journals

Sézary syndrome presenting with 'leonine facies'.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sézary syndrome presenting with 'leonine facies'. Australas J Dermatol. 2009 Nov;50(4):285-8 Authors: Nassem S, Kashyap R, Awasthi NP, Krishnani N, Kumari N A 71-year-old man presented with erythroderma and multiple nodular skin lesions over the face, scalp, upper limbs and trunk. The facial skin was thickened, producing the rare 'leonine facies' appearance. Investigations revealed the presence of atypical lymphoid cells in the peripheral blood, bone marrow and skin. The atypical lymphoid cells in the peripheral blood and bone marrow were positive for helper T-cell antigens (CD4, CD2, CD5 and CD7) on immun...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Nassem S, Kashyap R, Awasthi NP, Krishnani N, Kumari N Tags: Australas J Dermatol Source Type: journals

Rhinophyma: Carbon dioxide laser with computerized scanner is still an outstanding treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report demonstrates excellent cosmetic results and no major postoperative complications or recurrence of the condition after 1 year of follow up for seven patients. Two more patients had been followed up for 1 month at the time this paper was written. Scanned carbon dioxide laser is safe and highly effective treatment for rhinophyma. PMID: 19916975 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Lim SW, Lim SW, Bekhor P Tags: Australas J Dermatol Source Type: journals

Cutaneous malignant melanoma arising in an acquired naevus of Ota.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 32-year-old Caucasian man with an acquired naevus of Ota with subtle pigmentation, in which a melanocytic papule developed. The lesion, deceptively, had no clinically suspicious features, but investigation revealed an aggressive cutaneous malignant melanoma, extensive orbital ring melanocytosis and metastatic brain and subsequent liver disease. PMID: 19916976 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Patterson CR, Acland K, Khooshabeh R Tags: Australas J Dermatol Source Type: journals

Vulval location: an indication for staging in basal cell carcinoma?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19916978 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Suarez-Amor O, Monteagudo B, Cabanillas M, de las Heras C Tags: Australas J Dermatol Source Type: journals

Trichilemmal cyst with homogeneous blue pigmentation on dermoscopy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 61-year-old woman was referred to our dermoscopy unit for a pigmented lesion that had been present on her left arm for 8 years. The patient did not notice any enlargement or change in colour. On dermoscopy, homogeneous blue pigmentation was seen. The lesion was excised with the pre-operative diagnosis of melanoma, blue naevus and dermatofibroma. Histopathological examination showed a trichilemmal cyst in the mid-dermis. Although homogeneous blue pigmentation on dermoscopy is the hallmark of blue naevus, it may be seen in metastatic melanoma and exceptionally in hemosiderotic and cellular types of dermatofibroma. Tric...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Gencoglan G, Karaarslan IK, Akalin T, Ozdemir F Tags: Australas J Dermatol Source Type: journals

Abstracts of the Australasian College of Dermatologists Biennial Spring Conference. October 8-11, 2009. Hunter Valley, New South Wales, Australia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19754683 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - September 24, 2009 Category: Dermatology Tags: Australas J Dermatol Source Type: journals

Conditions masquerading as infantile haemangioma: Part 2.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infantile haemangiomas are among the most common growths during infancy. Their rapid growth during infancy and vascularity can easily cause confusion with other, less common growths. Part I focussed on other vascular anomalies that can mimic infantile haemangiomas. Part II emphasizes benign growths and malignant conditions that can also cause diagnostic confusion. PMID: 19659975 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Frieden IJ, Rogers M, Garzon MC Tags: Australas J Dermatol Source Type: journals

Evaluation of the treatment of non-melanoma skin cancers by surgical excision.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A retrospective study of all non-melanoma skin cancers excised by two dermatologists at a private practice in 2004 (excluding Mohs microscopic surgery cases) was conducted. Two hundred and forty-one patients were treated, with a total of 453 tumours excised. The overall incomplete excision rate was 2.2% (10/453). For basal cell cancers, the incomplete excision rate was 1.54% (5/324) and for squamous cell cancers including Bowen's disease the incomplete excision rate was 3.9% (5/129). The majority of repairs were primary closures (82.6%). Although a significant proportion of the tumours were from the head and neck regio...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Pua VS, Huilgol S, Hill D Tags: Australas J Dermatol Source Type: journals

Thoroughness of skin examination by melanoma patients: influence of age, sex and partner.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to determine the thoroughness of deliberate skin examination by people with a history of melanoma. Patients were randomized into one of two conditions: either to receive the brief educational and skills training intervention alone or as a couple with their spouse or cohabiting partner. Subjects recorded concerning lesions on body maps. At the 4-month visit, a total body skin examination was performed by a dermatologist blinded to the subjects' condition and to their recorded responses. The skin surface was divided according to the region's visibility during skin self-examination and sexual con...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Boone SL, Stapleton J, Turrisi R, Ortiz S, Robinson JK, Mallett KA Tags: Australas J Dermatol Source Type: journals

Comparative efficacy of thalidomide and prednisolone in the treatment of moderate to severe erythema nodosum leprosum: a randomized study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study was undertaken to compare the efficacy and safety of thalidomide to that of oral prednisolone in the treatment of moderate to severe type 2 lepra reaction. Sixty patients with a histologically confirmed diagnosis of erythema nodosum leprosum with a clinical score of 4 or more (i.e. moderate to severe type 2 reaction) were randomly allocated to two groups comprising 30 patients each. Group 1 patients were given thalidomide at a dose of 300 mg/day for 1 week and the dose was gradually reduced, and Group 2 received prednisolone 40 mg daily for 2 weeks, which was tapered by 10 mg every 2 weeks. Thalidomid...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Kaur I, Dogra S, Narang T, De D Tags: Australas J Dermatol Source Type: journals

Pseudoxanthoma elasticum-like lesions in association with thalassaemia major.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 33-year-old woman with a background of thalassaemia major presented with a 3-month history of yellowish plaques on the back of her neck bilaterally and alterations in the texture of the skin in both axillae. Examination of these lesions showed yellowish cobblestone plaques and coalescing papules in both axillae. Pseudoxanthoma elasticum (PXE)-like lesions were confirmed histopathologically. PXE-like lesions in association with thalassaemia major are an uncommon occurrence. Due to the increase in the survival rate of thalassaemia major patients on treatment, the development of these lesions is likely to increase. The ...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Yu S, Ming A, Wegman A Tags: Australas J Dermatol Source Type: journals

Erosive mucosal lichen planus and secondary epiphora responding to systemic cyclosporin A treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a woman with severe cicatrizing mucosal LP and ocular symptoms secondary to presumed nasolacrimal duct involvement. We also report the potential for this newly appreciated manifestation of LP to respond to systemic cyclosporin A. PMID: 19659981 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Boyce AE, Marshman G, Mills RA Tags: Australas J Dermatol Source Type: journals

Recurrent keratoacanthoma with vascular invasion: a diagnostic and management dilemma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 71-year-old man with chronic renal failure and on peritoneal dialysis presented with recurrence of multiple keratotic nodules along a surgical scar. This was 6 months after the excision of a recurrent keratotic nodule reported as squamous cell carcinoma from the same site. The lesions were initially reported as squamous cell carcinomas, but on review of histology were consistent with keratoacanthomas. One of the keratoacanthomas showed vascular invasion. These responded well to low-dose acitretin at 10 mg three times per week and the patient stayed in remission after 18 months of follow up. PMID: 19659982 [PubMed...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Kurien A, Henderson C, Lee S Tags: Australas J Dermatol Source Type: journals

Indurated reticulate palmar erythema as a sign of paraneoplastic palmar fasciitis and polyarthritis syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 62-year-old woman presented with a 6-month history of polyarthritis. She had also noted a 2-month history of indurated palmar erythema and increasing bilateral hand swelling and stiffness. A biopsy from the area of palmar erythema showed interstitial fibroplasia within the dermis and subcutis representing a palmar fibromatosis. This presentation appears to belong to the spectrum of palmar fasciitis and polyarthritis syndrome. Rheumatologists have recognised this syndrome as a paraneoplastic disorder and subsequent investigations in our patient revealed an elevated cancer antigen 125 and an inoperable ovarian carcinom...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Preda VA, Frederiksen P, Kossard S Tags: Australas J Dermatol Source Type: journals

Refractory subacute cutaneous lupus erythematosus successfully treated with rituximab.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 48-year-old woman presented with pruritic, scaly, annular plaques over her upper back and chest that were clinically, serologically and histologically characteristic of subacute cutaneous lupus erythematosus (SCLE). She failed to respond to conventional treatment, which included high-dose hydroxychloroquine, methotrexate, prednisolone, chloroquine, acitretin, thalidomide, dapsone and azathioprine. Subsequently treated with intravenous rituximab 375 mg/m(2) weekly for 4 weeks, she remained on adjuvant oral hydrochloroquine 600 mg daily and topical clobetasol propionate 0.05% ointment as required. Clearing of annular p...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Kieu V, O'Brien T, Yap LM, Baker C, Foley P, Mason G, Prince HM, McCormack C Tags: Australas J Dermatol Source Type: journals

Toxic epidermal necrolysis and neutropaenia: complications of omeprazole.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Worldwide, proton pump inhibitors (PPI) are one of the most frequently prescribed drugs; however, up to 70% of patients taking these drugs have no appropriate indication. Although PPI are relatively well tolerated, they are not free from side-effects and several life-threatening complications are associated with them. In the present report, a 43-year-old woman presented to her general practitioner with an erythematous rash over her face and chest, having been started on omeprazole for chronic abdominal bloating. Over the next 24 h she became increasingly unwell and was admitted to hospital with shortness of breath, pyr...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Thakor AS, Burke A, Handfield-Jones S, Sinha A, Palmer M, Burns A Tags: Australas J Dermatol Source Type: journals

Vitiligo-like depigmentation induced by imiquimod treatment of superficial basal cell carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 61-year-old man was treated with imiquimod 5% cream for superficial basal cell carcinoma, five times per week for 13 weeks. This resulted in vitiligo-like depigmentation and poliosis in the area of treatment. This rare side-effect has been noted in previous case reports of imiquimod treatment for both genital warts and superficial basal cell carcinoma. This highlights the importance of such a side-effect being discussed with the patient who is to be treated with imiquimod, particularly in cosmetically sensitive areas. PMID: 19659986 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Sriprakash K, Godbolt A Tags: Australas J Dermatol Source Type: journals

Repigmentation and curling of hair after acitretin therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 70-year-old woman with psoriasis who noticed darkening of her previously white hair, which also gained a curly appearance after 6 months of acitretin treatment. We present this case to emphasize that acitretin can be added to the list of drugs that induce changes in hair colour and texture. PMID: 19659987 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Seckin D, Yildiz A Tags: Australas J Dermatol Source Type: journals

Granuloma faciale successfully treated with topical tacrolimus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a man with a 6-month history of plaques on his forehead and preauricular area consistent with GF that responded to twice-daily application of topical tacrolimus ointment, and who remains in remission 1 year later. This case supports previous reports of the successful use of topical tacrolimus in treating GF. PMID: 19659988 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Patterson C, Coutts I Tags: Australas J Dermatol Source Type: journals

Primary umbilical melanoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 72-year-old woman who presented with a primary melanoma of the umbilicus and periumbilical skin of 4 years' duration. Pathological examination of a biopsy specimen showed Clark's level IV, and tumour thickness 2.3 mm. The patient underwent preoperative lymphatic mapping followed by sentinel lymph node biopsy, and wide local excision of the primary tumour, including its attachment to the peritoneum. Because of the variations in vascularity and the residual embryonal connections of the umbilicus with the peritoneum and other intra-abdominal organs, an aggressive surgical approach is recommended in the management ...
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Cecchi R, Pavesi M, Buralli L, Rapicano V, De Gaudio C Tags: Australas J Dermatol Source Type: journals

About vascular patterns.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19659990 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Rubegni P, Mandato F, Biagioli M, Fimiani M Tags: Australas J Dermatol Source Type: journals

Unusual clinical and dermoscopic presentation of a wart.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19659993 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - July 31, 2009 Category: Dermatology Authors: Yoong C, Di Stefani A, Hofmann-Wellenhof R, Campbell T, Soyer HP Tags: Australas J Dermatol Source Type: journals

Abstracts of the Australasian College of Dermatologists 42nd Annual Scientific Meeting. May 17-20, 2009. Broadbeach, Queensland, Australia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19366345 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Tags: Australas J Dermatol Source Type: journals

Conditions masquerading as infantile haemangioma: Part 1.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article focuses on the myriad of diagnostic mimics of haemangiomas, including other vascular anomalies, benign growths, and malignancies. PMID: 19397559 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Frieden IJ, Rogers M, Garzon MC Tags: Australas J Dermatol Source Type: journals

Eczema workshops reduce severity of childhood atopic eczema.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, patients attending the eczema workshop had a greater improvement in eczema severity thanpatients attending a dermatologist-led clinic, supporting collaborative models of service provision. PMID: 19397561 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Moore EJ, Williams A, Manias E, Varigos G, Donath S Tags: Australas J Dermatol Source Type: journals

Electronic e-isotretinoin prescription chart: improving physicians' adherence to isotretinoin prescription guidelines.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Oral isotretinoin is a highly effective treatment for refractory nodulocystic acne. However, it can be associated with serious adverse effects such as teratogenicity and hepatitis. Inadequate cumulative dosing may also result in reduced therapeutic efficacy and higher disease relapse. A preliminary audit had previously revealed a poor and inconsistent adherence to local isotretinoin prescribing guidelines by physicians. To achieve greater than 90% adherence to isotretinoin guidelines for all acne patients prescribed systemic isotretinoin at the National Skin Centre, Singapore, key areas and the reasons for non-adherenc...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Tang MB, Tan ES, Tian EA, Loo SC, Chua SH Tags: Australas J Dermatol Source Type: journals

Successful treatment of female-pattern hair loss with spironolactone in a 9-year-old girl.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 9-year-old prepubertal girl with female pattern hair loss treated with spironolactone 100 mg orally per day had objective improvement demonstrated by regrowth observed clinically and on comparison of pre- and post-treatment stereotactic scalp photographs taken 6 months apart. PMID: 19397563 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Yazdabadi A, Green J, Sinclair R Tags: Australas J Dermatol Source Type: journals

Vulval and perianal inflammatory linear verrucous epidermal naevus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of ILVEN occurring on the vulva and perianal region of a 6-year-old girl. The lesion was initially thought to be an area of lichenified dermatitis; however, treatment with even super-potent topical corticosteroids did not significantly improve the inflammation. A biopsy was performed and histopathological examination showed characteristic features. ILVEN is frequently refractory to topical treatment and surgical excision of lesions may be an option for relief of symptoms. ILVEN occasionally presents in the inguinogenital region and in this area may, like many vulval naevi, be misdiagnosed as vulvitis, pso...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Le K, Wong LC, Fischer G Tags: Australas J Dermatol Source Type: journals

Vulval fixed drug eruption due to paracetamol.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a case of FDE due to paracetamol presenting as a chronic erosive vulvitis in an older woman taking multiple medications. Diagnosis was delayed because paracetamol is available without prescription, taken intermittently and may be omitted from the clinical history. Cessation of paracetamol led to prompt resolution of symptoms. Consideration should be given to paracetamol as a cause of FDE presenting as a chronic erosive vulvitis. PMID: 19397565 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Drummond C, Fischer G Tags: Australas J Dermatol Source Type: journals

Delayed diagnosis of Gorlin's syndrome in a renal transplant recipient.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 35-year-old woman was referred to the dedicated dermatology clinic for RTR. She underwent her first renal transplant at 18 years of age due to chronic renal failure following reflux nephropathy of the single right kidney (left kidney agenesis). She has since then had two further transplants. During clinical examination she was noted to have at least 16 basal cell carcinomas (BCC) and there are records in the case notes of 10 BCC having being excised and confirmed histologically in the past. By contrast, she had only had two squamous cell carcinomas (SCC) excised. She was also noted to have distinctive facial features...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Mackenzie KA, Maurice PD Tags: Australas J Dermatol Source Type: journals

Allergic contact dermatitis from exposure to Grevillea robusta in New Zealand.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There are a number of reports in the literature of allergic contact dermatitis as a result of exposure to the sawdust and plant parts of Grevillea robusta. While this tree is prevalent in New Zealand, there seems to have been no previous published accounts of contact dermatitis, although anecdotal evidence indicates that such cases may be common. Two brief case reports are provided regarding severe phytodermatitis to G. robusta among professional arborists in New Zealand. As with other common plants capable of inducing allergic contact dermatitis, greater awareness among arborists, orchardists, forestry workers, garden...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Derraik JG, Rademaker M Tags: Australas J Dermatol Source Type: journals

Successful treatment of lymphomatoid papulosis with photodynamic therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 40-year-old woman presented with a prolonged history of recurrent crops of erythematous papules and nodules on her abdomen, arms and legs. Histological examination of a cutaneous biopsy revealed Type A lymphomatoid papulosis. Over a 3-year period, some of the patient's lesions had proven to be resistant to treatment with topical and intralesional corticosteroids and systemic agents including methotrexate, tetracycline and nicotinamide. These resistant lesions were treated with two sessions of methyl aminolevulinate photodynamic therapy given 1 week apart. Review 11 months post-photodynamic therapy demonstrated comple...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Rodrigues M, McCormack C, Yap LM, Prince HM, Roberts H, Williams R, Foley P Tags: Australas J Dermatol Source Type: journals

Solitary mastocytoma occurring at a site of trauma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a patient with a solitary mastocytoma arising at a site of trauma. The patient was born with the umbilical cord wrapped around her right thigh and subsequently developed a solitary mastocytoma in the exact site and distribution of this injury. The pathogenesis of mast cell proliferation in solitary mastocytoma is not completely understood. Cytokines released after injury, such as stem cell factor, may stimulate the proliferation of mast cells, as well as fibroblasts and melanocytes to form a mastocytoma. Mast cells in a newborn may be more sensitive to stem cell factor in the presence of cytokines released afte...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Tuxen AJ, Orchard D Tags: Australas J Dermatol Source Type: journals

Unusual presentation of GLUT-1 positive infantile haemangioma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infantile haemangiomas are usually not present at birth. This is a case of a female infant with an atypical congenital vascular tumour present at birth which ulcerated in the first few days of life, involuted over several months and showed histopathological features in keeping with either an involuting GLUT-1 positive infantile haemangioma or a reticular haemangioma of infancy. The initial clinical presentation was atypical for an infantile haemangiomas and for a congenital haemangioma, however the histopathology and immunohistochemistry assisted with confirmation of the diagnosis. Vacuum-assisted closure (VAC) therapy...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Koh C, Sugo E, Wargon O Tags: Australas J Dermatol Source Type: journals

Pyogenic granuloma complicating pulsed-dye laser therapy for cherry angioma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 37 year-old-woman presented for cosmetic removal of a 7-mm (diameter) cherry angioma on her right anterior thigh. Various treatment options were discussed and removal of the lesion using pulsed-dye laser was carried out. The patient returned 5 weeks later complaining of bleeding from the treatment site, which on examination showed a 23 x 23-mm friable nodular lesion with the typical appearance of a pyogenic granuloma. This lesion was removed by shave excision, curettage and electrodessication. Histopathological examination confirmed the diagnosis of pyogenic granuloma. This is a rare occurrence post pulsed-dye laser ...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Cheah S, DeKoven J Tags: Australas J Dermatol Source Type: journals

Subungual and periungual congenital blue naevus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 21-year-old Hispanic woman with a slowly enlarging 1.7 x 2.3-cm subungual and periungual pigmented plaque present since birth on her right second toe. Initial biopsy was consistent with a blue naevus of the cellular type and, given the recent clinical change and periungual extension, complete excision was recommended. The entire nail unit was resected down to periosteum with prior avulsion of the nail plate. Reconstruction was performed with a full-thickness skin graft. Follow up at 1 year revealed well-healed graft and donor sites with complete return of function. We present a case of a congenital subungual an...
Source: The Australasian Journal of Dermatology - April 30, 2009 Category: Dermatology Authors: Gershtenson PC, Krunic A, Chen H, Konanahalli M, Worobec S Tags: Australas J Dermatol Source Type: journals

Acquired dermal melanocytosis involving the hand.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19178500 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - February 1, 2009 Category: Dermatology Authors: Garg T, Ramchander , Srihar R, Gupta TP Tags: Australas J Dermatol Source Type: journals

The most common challenges in melanoma diagnosis and how to avoid them.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Due to its particularly lethal nature and tendency to affect relatively young individuals, the timely diagnosis of melanoma remains of paramount importance for clinicians and their patients. Unfortunately, melanomas can mimic benign lesions that are overwhelmingly more common in the population than are melanomas, and misdiagnosis or delay in diagnosis of melanoma can occur. Misdiagnosis of melanoma serves as one of the most common causes for malpractice litigation brought against medical practitioners. In this review we describe seven clinical scenarios that represent challenges in melanoma diagnosis and discuss potent...
Source: The Australasian Journal of Dermatology - January 31, 2009 Category: Dermatology Authors: Marghoob AA, Changchien L, Defazio J, Dessio WC, Malvehy J, Zalaudek I, Halpern AC, Scope A Tags: Australas J Dermatol Source Type: journals

Select the most correct answers - multiple answers possible for questions 1-11.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19178486 [PubMed - in process] (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - January 31, 2009 Category: Dermatology Tags: Australas J Dermatol Source Type: journals

PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: Results of a randomized, double-blind, vehicle-controlled, multicentre, phase IIa study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The sap of the plant Euphorbia peplus is a traditional remedy for skin conditions, including actinic keratosis. The active constituent of the sap is ingenol mebutate (ingenol-3-angelate), formerly known as PEP005. This randomized, double-blind, vehicle-controlled, phase IIa study investigated the safety (and secondarily the efficacy) of two applications of ingenol mebutate gel in 58 patients with biopsy-confirmed actinic keratosis. Five preselected lesions were treated with ingenol mebutate gel, 0.0025%, 0.01% or 0.05%, or vehicle gel, on days 1 and 2 (Arm A) or days 1 and 8 (Arm B). There were no significant differenc...
Source: The Australasian Journal of Dermatology - January 31, 2009 Category: Dermatology Authors: Siller G, Gebauer K, Welburn P, Katsamas J, Ogbourne SM Tags: Australas J Dermatol Source Type: journals

Perioperative management and the associated rate of adverse events in dermatological procedures performed by dermatologists in New Zealand.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dermatological surgery performed in an outpatient setting is common and generally perceived as safe, but the potential for serious adverse events does exist. Furthermore, there is a current lack of guidelines regarding preoperative and intraoperative monitoring of such patients. This is a retrospective study that involved a written questionnaire sent to current practising New Zealand dermatologists. Aspects investigated include their practice relating to preoperative assessments and intraoperative monitoring during standard dermatological procedures, and the resulting rate of adverse events. We found that most responde...
Source: The Australasian Journal of Dermatology - January 31, 2009 Category: Dermatology Authors: Chan BC, Patel DC Tags: Australas J Dermatol Source Type: journals