The British Journal of Ophthalmology
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Emerging Treatment Paradigms of Ocular Surface Disease: Proceedings of the Ocular Surface Workshop.
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The objective of the Ocular Surface Workshop in Rome, Italy, on 6 February 2009, was to enhance the understanding of ocular surface disease (OSD) through exploration of the nature of its complexities and current treatment paradigms across Europe. It was hoped that the peer-to-peer discussions and updates regarding common knowledge, clinical practices, and shared experiences at this workshop would subsequently shape future treatment approaches to OSD in Europe.
PMID: 19910284 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 11, 2009 Category: Opthalmology Authors: Rolando M, Geerling G, Dua HS, Benítez-Del-Castillo JM, Creuzot-Garcher CP Tags: Br J Ophthalmol Source Type: journals
Elevated serum IL-23 correlates with intraocular inflammation after cataract surgery in patients with Vogt-Koyanagi-Harada disease.
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CONCLUSIONS: Our data indicate that serum IL-23 levels are significantly elevated in VKH vs. control patients and strongly associated with postoperative intraocular inflammation.
PMID: 19910285 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 11, 2009 Category: Opthalmology Authors: Jiang S, Liu X, Luo L, Qu B, Huang X, Xu L, Lin Y, Ye S, Liu Y Tags: Br J Ophthalmol Source Type: journals
Postoperative infection in penetrating versus non-penetrating glaucoma surgery.
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CONCLUSIONS: The literature on infections related to non-penetrating glaucoma surgery is sparse, in contrast to that for trabeculectomy and glaucoma drainage device procedures. Thus far, no case of endophthalmitis has been reported following non-penetrating glaucoma surgery, even with the use of intraoperative antimetabolites. However, there is currently insufficient evidence to conclusively demonstrate that NPGS is associated with significantly less risk of endophthalmitis and infection when compared to trabeculectomy and glaucoma drainage device implantation.
PMID: 19897472 [PubMed - as supplied by publisher] (Source...
Source: The British Journal of Ophthalmology - November 5, 2009 Category: Opthalmology Authors: Ang GS, Varga Z, Shaarawy T Tags: Br J Ophthalmol Source Type: journals
Periorbital Necrotizing Fasciitis.
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Necrotizing fasciitis involving the periorbita is a devastating infection which potential outcomes range from severe disfigurement, loss of the eye, and even to death. Early recognition is critical though its initially nondistinctive appearance frequently delays diagnosis and treatment. Herein, the authors have performed a systematic review of previously published cases including clinical features, diagnoses and differential diagnoses, pathologic characteristics, and management. Periorbital necrotizing fasciitis is seen mainly in adults with a female predominance (54%); about half (47%) of the patients are previously h...
Source: The British Journal of Ophthalmology - November 5, 2009 Category: Opthalmology Authors: Lazzeri D, Lazzeri S, Figus M, Tascini C, Bocci G, Colizzi L, Giannotti G, Lorenzetti F, Gandini D, Danesi R, Menichetti F, Del Tacca M, Nardi M, Pantaloni M Tags: Br J Ophthalmol Source Type: journals
Estimation of effects of community intervention with Antibiotics, Facial cleanliness, and Environmental improvement (A,F,E) in five districts of Ethiopia hyper-endemic for trachoma.
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CONCLUSION: These findings are important since they make the case for continued implementing the A,F,E interventions simultaneously, and suggest appropriate timing of SAFE evaluations within 6-12 months after the last mass azithromycin distribution.
PMID: 19897474 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 5, 2009 Category: Opthalmology Authors: Ngondi JM, Gebre T, Shargie EB, Adamu L, Teferi T, Zerihun M, Ayele B, King JD, Cromwell EA, Emerson PM Tags: Br J Ophthalmol Source Type: journals
Current treatment options for retinal angiomatous proliferans (RAP).
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Retinal angiomatous proliferation (RAP) accounts for 12-15% of all patients with neovascular age related macular degeneration (NV-AMD). However, this subtype is often excluded from clinical trials aimed at assessing the efficacy of various treatment options for NV-AMD. So, there are no established protocols for the management of RAP. This review of current literature on RAP compares the outcomes of various treatment options for this condition and highlights the lack of clinical trials and paucity of long-term data on this relatively common condition.
PMID: 19897475 [PubMed - as supplied by publisher] (Source: The B...
Source: The British Journal of Ophthalmology - November 5, 2009 Category: Opthalmology Authors: Gupta BM, Jyothi S, Sivaprasad S Tags: Br J Ophthalmol Source Type: journals
One year outcomes of a bilateral randomized prospective clinical trial comparing PRK with Mitomycin C and LASIK.
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CONCLUSIONS: Wavefront-guided PRK with 0.002% MMC was more effective than wavefront-guided LASIK for correction of moderate myopia. Further research is necessary to determine the optimal concentration, exposure time and the long-term corneal side effect of MMC.
PMID: 19889831 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 4, 2009 Category: Opthalmology Authors: Wallau AD, Campos M Tags: Br J Ophthalmol Source Type: journals
Architecture and distribution of human corneal nerves.
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CONCLUSIONS: This study provides a comprehensive account of the architecture and distribution of nerves in the human cornea. It reconciles some of the existing information obtained from other modalities of investigation and identifies some novel features which provide a more complete picture of corneal innervation.
PMID: 19889832 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 4, 2009 Category: Opthalmology Authors: Al-Aqaba M, Fares U, Suleman H, Lowe J, Dua HS Tags: Br J Ophthalmol Source Type: journals
Oxidative Stress of Intracameral Lidocaine and Levobupivacaine on Ocular Tissues.
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CONCLUSIONS: The results of this study suggest that levobupivacaine 0.5% is shown to have an immediate toxicity on corneal endothelium. Lidocaine 2% causes oxidative damage on corneal and lens tissues. Surgeons should not prefer repetitive and high doses of intracameral lidocaine and use it in the presence of corneal pathology during cataract surgery.
PMID: 19887439 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - November 2, 2009 Category: Opthalmology Authors: Demir MN, Demir ZA, Yalçyn Tök O, Yylmaz FM, Yylmaz G, Nurözler AB, Ornek F Tags: Br J Ophthalmol Source Type: journals
At a glance.
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PMID: 19854734 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Dua HS, Singh AD Tags: Br J Ophthalmol Source Type: journals
Helicobacter pylori: an intruder involved in conspiring glaucomatous neuropathy.
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PMID: 19854735 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Kountouras J Tags: Br J Ophthalmol Source Type: journals
Electric Eyes: Wirtz iontophoresis electrodes.
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PMID: 19854736 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Keeler R, Singh AD, Dua HS Tags: Br J Ophthalmol Source Type: journals
Management of acquired nasolacrimal duct obstruction: external and endonasal dacryocystorhinostomy. Is there a third way?
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PMID: 19854737 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Patel BC Tags: Br J Ophthalmol Source Type: journals
Glaucoma and Helicobacter pylori infection: correlations and controversies.
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A possible association between Helicobacter pylori infection (fig 1) and eye diseases, including Sjögren syndrome, blepharitis, central serous chorioretinopathy and uveitis, has been proposed. Glaucoma is the second leading cause of blindness in the world, after cataracts, and the leading cause of irreversible blindness, but many aspects of its pathogenesis remain unknown. H pylori infection may influence the pathophysiology of glaucoma by releasing various proinflammatory and vasoactive substances, as well as by influencing the apoptotic process, parameters that may also exert their own effects in the induction a...
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Izzotti A, Saccà SC, Bagnis A, Recupero SM Tags: Br J Ophthalmol Source Type: journals
Cataract surgery and primary intraocular lens implantation in children
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DISCUSSION: Primary IOL implantation in children </=2 has been widely adopted in the UK and Ireland. There is concordance of practice with regards to surgical technique and choice of IOL model. However, there is some variation in eligibility criteria for primary IOLs: this may reflect a lack of consensus on which children are most likely to benefit. Thus, there is a need for systematic studies of the outcomes of primary IOL implantation in younger children.
PMID: 19854739 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Solebo AL, Russell-Eggitt I, Nischal KK, Moore AT, Cumberland P, Rahi JS, Tags: Br J Ophthalmol Source Type: journals
Intraobserver variability of confocal scanning laser ophthalmoscopy with and without stereo photographs.
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PMID: 19854740 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Nguyen HT, Pikey KP, Gardiner SK, Gritz D, Krishnadas R, Cioffi GA, Mansberger SL Tags: Br J Ophthalmol Source Type: journals
Efficacy of infliximab therapy in two patients with refractory Vogt-Koyanagi-Harada disease.
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PMID: 19854741 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: Niccoli L, Nannini C, Cassarà E, Gini G, Lenzetti I, Cantini F Tags: Br J Ophthalmol Source Type: journals
Episcleritis following keratorefractive surgery.
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PMID: 19854742 [PubMed - in process] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 28, 2009 Category: Opthalmology Authors: D'Arcy F, Kirwan C, O'Keefe M Tags: Br J Ophthalmol Source Type: journals
Long-Term Visual and Anatomic Outcomes Following Anti-VEGF Monotherapy for Retinal Angiomatous Proliferation.
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CONCLUSIONS: Anti-VEGF monotherapy represents a useful treatment option for RAP, with stable or improved visual acuity in 62.5% of patients at 2 years. Although 25% of eyes only required a single injection, in most cases (75%) repeated treatments were required, therefore long-term follow-up is recommended.
PMID: 19854733 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 23, 2009 Category: Opthalmology Authors: Hemeida TS, Keane PA, Dustin L, Sadda SR, Fawzi AA Tags: Br J Ophthalmol Source Type: journals
Descemet's membrane endothelial keratoplasty with a stromal rim (DMEK-S).
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CONCLUSIONS: Preliminary outcomes show that DMEK-S may be used in the treatment of corneal endothelial dysfunction. As this approach is entirely manual and no special surgical equipment is needed, it has the potential to become widely adopted.
PMID: 19850580 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 21, 2009 Category: Opthalmology Authors: Studeny P, Farkas A, Vokrojova M, Liskova P, Jirsova K Tags: Br J Ophthalmol Source Type: journals
Prevalence of Heterophoria and Associations with Refractive Error, Heterotropia and Ethnicity in Australian School Children.
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CONCLUSION: Contrary to other studies, exophoria, not orthophoria, was predominant for near. Exophoria was more prevalent in children of East Asian origin. Longitudinal studies are needed to establish if incident heterotropia is preceded by heterophoria.
PMID: 19850581 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 21, 2009 Category: Opthalmology Authors: Leone JF, Kifley A, Morgan IG, Wang JJ, Cornell E, Mitchell P, Rose KA Tags: Br J Ophthalmol Source Type: journals
Detection of Mycobacterium tuberculosis in Corneas from Donors with Active TB Disease thru Polymerase Chain Reaction and Culture.
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CONCLUSION: PCR for M. tuberculosis was positive for some TB positive donors and well as TB negative donors.But all cultures was negative. It is recommended that further studies be done to investigate if recipients with PCR positive corneas will eventually lead to disease transmission or not. It is further recommended that such findings be used to re-evaluate criteria for suitability of donors with tuberculosis.
PMID: 19850582 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 21, 2009 Category: Opthalmology Authors: Jover E, Santos R, Padilla MD, Fajardo-Ang C Tags: Br J Ophthalmol Source Type: journals
Clinical evaluation of the MacuScopeTM macular pigment densitometer.
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CONCLUSIONS: If MPOD is being monitored over time then any change less than 0.58 units should not be considered clinically significant as it is very likely to be due to measurement noise. The size of the coefficient appears to be positively correlated with MPOD.
PMID: 19850583 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 21, 2009 Category: Opthalmology Authors: Bartlett HE, Acton JH, Eperjesi F Tags: Br J Ophthalmol Source Type: journals
Psychosocial Impact of Visual Impairment in Working Age Adults.
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CONCLUSIONS: Future research is required into the prevalence of loneliness, anxiety, and depression in adults with visual impairment, and to evaluate the effectiveness of interventions for improving psychosocial well-being such as counselling, peer support, and employment programmes.
PMID: 19850584 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 21, 2009 Category: Opthalmology Authors: Nyman SR, Gosney MA, Victor CR Tags: Br J Ophthalmol Source Type: journals
An inter-rater reliability study of a new "zonal" classification for reporting the location of retinal haemorrhages in childhood for clinical, legal and research purposes.
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CONCLUSION: This new retinal zone classification and the use of photographs and templates is a very reliable tool for reporting the location of retinal haemorrhages from multiple aetiologies in children, and may be useful for research and medico-legal reports.
PMID: 19846410 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 20, 2009 Category: Opthalmology Authors: Fleck BW, Tandon A, Jones PA, Mulvihill AO, Minns RA Tags: Br J Ophthalmol Source Type: journals
New Observations Concerning the Nature of the Central Retinal Vein Pulsation.
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CONCLUSION: During venous pulsation, the venous collapse occurred in time with ocular diastole and dilatation in time with systole. This is contrary to prior conceptual understanding. Our results suggest that the intracranial pulse pressure may be of equal importance to IOP pulse pressure in producing venous pulsation.
PMID: 19846411 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 20, 2009 Category: Opthalmology Authors: Kain S, Morgan WH, Yu DY Tags: Br J Ophthalmol Source Type: journals
Indocyanine Green Angiography-Guided Laser Photocoagulation Combined with Sub-Tenon's Capsule Injection of Triamcinolone Acetonide for Idiopathic Macular Telangiectasia.
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CONCLUSIONS: IA can detect microangiopathy in eyes with idiopathic macular telangiectasia. IA-guided laser photocoagulation combined with STTA might be effective for treating types 1 and 2 idiopathic macular telangiectasia. Further studies are needed to access the efficacy of IA-guided photocoagulation for treating type 2 telangiectasia.
PMID: 19846412 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 20, 2009 Category: Opthalmology Authors: Hirano Y, Yasukawa T, Usui Y, Nozaki M, Ogura Y Tags: Br J Ophthalmol Source Type: journals
Air regurgitation in patients on continuous positive airway pressure (CPAP) therapy following dacrocystorhinostomy with or without Lester Jones tube insertion.
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CONCLUSION: Air regurgitation can occur following naso-lacrimal surgery in patients on CPAP therapy. Although this is an unusual complication, it should be discussed with the patient at the time of obtaining informed consent.
PMID: 19846413 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 20, 2009 Category: Opthalmology Authors: Cannon PS, Madge SN, Selva D Tags: Br J Ophthalmol Source Type: journals
Choroidal Filling Delay in Choroidal Neovascularization due to Pathologic Myopia.
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CONCLUSION: Significant choroidal changes were observed in eyes with mCNV. Ischemia-induced growth factor expression caused by decreased choroidal perfusion may be related to the development of mCNV.
PMID: 19846414 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 20, 2009 Category: Opthalmology Authors: Wakabayashi T, Ikuno Y Tags: Br J Ophthalmol Source Type: journals
Ocular firework trauma: a systematic review on incidence, severity and prevention.
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CONCLUSIONS: One in six ocular firework traumas show severe vision loss, mostly in young males. Bystanders are as frequently injured. Firework traumas are a preventable cause of severe ocular injury and blindness since countries employing restrictive firework legislation have remarkable lower trauma incidence rates.
PMID: 19846415 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 19, 2009 Category: Opthalmology Authors: Wisse RP, Bijlsma WR, Stilma JS Tags: Br J Ophthalmol Source Type: journals
Time course of changes in ocular wavefront aberration after instillation of 0.5% timolol gel-forming solution.
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CONCLUSION: EInstillation of timolol gel-forming solution significantly degrades optical quality of the eye for approximately 5 minutes by increasing HOAs, which may cause blurred vision.
PMID: 19843537 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 18, 2009 Category: Opthalmology Authors: Hiraoka T, Daito M, Okamoto F, Kiuchi T, Hirohara Y, Mihashi T, Oshika T Tags: Br J Ophthalmol Source Type: journals
Assessment of corneal biomechanical properties and intraocular pressure with Ocular Response Analyzer in childhood myopia.
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CONCLUSION: Lower CH and CRF were associated with longer AL but not corneal curvature. The association between lower CH and deeper ACD demonstrated the importance of CH as a determinant of ocular biometry in both the anterior and posterior segments. Differences in corneal biomechanical properties may indicate more generalized structural differences between eyes.
PMID: 19833612 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Chang PY, Chang SW, Wang JY Tags: Br J Ophthalmol Source Type: journals
Measurement of corneal aberrations for customization of intraocular lens asphericity: impact on quality of vision after micro-incision cataract surgery.
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CONCLUSION: Individual selection of IOL asphericity with a preoperative corneal SA measurement allowed control of final ocular SA. Such customization improves mesopic contrast sensitivity, and leads to better objective quality of vision.
PMID: 19833613 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Nochez Y, Favard A, Majzoub S, Pisella PJ Tags: Br J Ophthalmol Source Type: journals
Precut Donor Tissue for Descemet Stripping Automated Keratoplasty: Anterior Hinged Lamella On versus Off.
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CONCLUSION: Eye-bank prepared tissue offers the potential advantage of being screened for mechanical stress damage occurring during the automated dissection.
PMID: 19833614 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Amato D, Oddone F, Nubile M, Colabelli Gisoldi RA, Villani CM, Pocobelli A Tags: Br J Ophthalmol Source Type: journals
Exfoliation syndrome in the Reykjavik Eye Study: Risk factors for Baseline Prevalence and 5-Year Incidence.
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CONCLUSION: Food items that are possibly surrogates for antioxidative effect may correlate with decreased risk of XFS and increased iris pigmentation may correlate with increased risk. Given the large number of comparisons, our findings require validation through additional clinical studies. Increased age and female gender increase likelihood of XFS.
PMID: 19833615 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Arnarsson A, Jonasson F, Damji KF, Gottfredsdottir MS, Sverrisson T, Sasaki H Tags: Br J Ophthalmol Source Type: journals
Test-retest variability of intraocular pressure and ocular pulse amplitude for Dynamic Contour Tonometry: a multicenter study.
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DISCUSSION: DCT test-retest variability was almost perfect for IOP and good for OPA. Tonometry measurements with DCT tended to be overestimated compared to GAT.
PMID: 19833616 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Fogagnolo P, Figus M, Frezzotti P, Iester M, Oddone F, Zeppieri M, Ferreras A, Brusini P, Rossetti L, Orzalesi N Tags: Br J Ophthalmol Source Type: journals
F4H5 - A Novel Substance for the Removal of Silicone Oil from Intraocular Lenses.
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CONCLUSION: F4H5 was highly effective at removing the bulk of the silicone oil from all three groups of IOL. The dynamic contact angle measurements suggested that their surface properties were permanently modified.
PMID: 19828515 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Stappler T, Williams R, Wong D Tags: Br J Ophthalmol Source Type: journals
Basophils in the giant papillae of chronic allergic keratoconjunctivitis.
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CONCLUSION: Basophils may infiltrate from either vascular endothelium into the giant papillae. The existence of basophils at the center of inflammatory cells suggests the role of basophils as an initiator of chronic allergic conjunctivitis.
PMID: 19828516 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Matsuda A, Ebihara N, Yokoi N, Okayama Y, Watanabe Y, Kawasaki S, Tanioka H, Walls AF, Hamuro J, Kinoshita S, Murakami A Tags: Br J Ophthalmol Source Type: journals
Twenty-three Gauge Cannula System with Microvitreoretinal Blade Trocar.
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CONCLUSION: The MVR trocar-cannula leads to better postoperative wound closure and reduces the incidence of postoperative hypotony.
PMID: 19828517 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Inoue M, Shinoda K, Hirakata A Tags: Br J Ophthalmol Source Type: journals
Clinical consequences of acrylic intraocular lens material and design: Nd:YAG-laser capsulotomy rates in 3 x 300 eyes 5 years after phacoemulsification.
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CONCLUSION: In comparison with a hydrophobic acrylic IOL with sharp posterior optic edge, a hydrophilic acrylic IOL was associated with almost twice the number of Nd:YAG-laser treatments over the five-year period. The results are useful for discussing the economic long-term consequences of choosing an IOL with a design that makes PCO development more or less likely. Caution is advised when applying data from post-mortem PCO studies on living populations.
PMID: 19828518 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Johansson B Tags: Br J Ophthalmol Source Type: journals
The world through a lens: the vision of Sir Harold Ridley.
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Sir Harold Ridley is recognized today as the inventor of the intraocular lens, one the most successful and common procedures in all of surgery. His story, however, is not largely one of triumph and public accolade. This paper reviews Ridley's invention of the intraocular lens and highlights the struggles he faced after his discovery.
PMID: 19828519 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 13, 2009 Category: Opthalmology Authors: Moore DB, Harris A, Siesky B Tags: Br J Ophthalmol Source Type: journals
Twenty-four hour intraocular pressure control with bimatoprost and bimatoprost/timolol fixed combination administered in the morning, or evening in exfoliative glaucoma.
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CONCLUSION: Both BTFC dosing regimens significantly reduce 24-hour IOP in XFG compared with bimatoprost monotherapy. The evening dosing gives rise to statistically better 24-hour IOP control and could be considered in these patients.
PMID: 19825835 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Konstas AG, Hollo G, Mikropoulos D, Tsironi S, Haidich AB, Embeslidis T, Irkec M, Melamed S Tags: Br J Ophthalmol Source Type: journals
Confocal Microscopy Study of Donor-Recipient Interface Following Descemet's Stripping with Endothelial Keratoplasty.
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CONCLUSION: Subepithelial haze, donor-recipient stromal interface haze, birefringent particles and stromal folds were present at different degrees in all patients that underwent DSEK. However, subepithelial haze was the only factor that correlated to postoperative BSCVA.
PMID: 19825836 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Espana E, Huang B Tags: Br J Ophthalmol Source Type: journals
The Marshall M. Parks Memorial LectureMaking Sense of Early-Onset Childhood Retinal Dystrophies - The Clinical Phenotype of Leber Congenital Amaurosis.
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A correct diagnosis of the early onset childhood retinal dystrophies requires careful clinical evaluation, the detection of suggestive or pathognomonic ophthalmoscopic clues, the use of electrophysiology to document characteristic electroretinographic (ERG) findings, and in some cases, the utilization of newer diagnostic modalities such as optical coherence tomography (OCT). Molecular diagnosis confirms the clinical diagnosis and provides the basis for possible future gene therapy. A strict definition of early-onset childhood retinal dystrophies (EOCRD) does not exist but inherited retinal dystrophies that are diagnose...
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Traboulsi EI Tags: Br J Ophthalmol Source Type: journals
Ultrasound Biomicroscopy and Iris Pigment Dispersion: a Case-Control Study.
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CONCLUSION: All UBM parameters considered were statistically different between the two groups. ROC analysis showed ICA and IC in near vision to be the most discriminant parameters. This evidence confirms the importance of iris movements in inducing the peculiar features of PDS/PG.
PMID: 19822906 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Mora P, Sangermani C, Ghiradini S, Carta A, Ungaro N, Gandolfi SA Tags: Br J Ophthalmol Source Type: journals
Mizuo-Nakamura phenomenon with a negative waveform ERG.
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A 79 year old Pakistanian male with complaints of nyctalopia and progressive decline of vision in both eyes was evaluated and found to exhibit the Mizuo-Nakamura phenomenon on fundoscopic examination. Dark adapted, bright flash ERG testing revealed a prominent negative waveform morphology. Fluorescein angiography and autofluorescent imaging were obtained and the results were consistent with a bulls eye maculopathy. Due to the patient's subjective complaints of nyctalopia, the Mizuo-Nakamura phenomenon and the negative waveform ERG, a presumptive diagnosis of Oguchi's disease was made. However, genetic testing failed to...
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Yuan A, Nusinowitz S, Sarraf D Tags: Br J Ophthalmol Source Type: journals
Systemic and ophthalmological anomalies in congenital anophthalmic or microphthalmic patients.
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CONCLUSIONS: All children born with congenital anophthalmos or microphthalmos require a thorough clinical examination by an experienced ophthalmologist to rule out pathology in the fellow eye in unilateral disease and by a paediatrician to screen for any associated systemic anomalies.
PMID: 19822908 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Schittkowski MP, Guthoff RF Tags: Br J Ophthalmol Source Type: journals
MR Imaging of Familial Superior Oblique Hypoplasia.
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CONCLUSION: Superior oblique hypoplasia confirmed with MRI was useful for clarifying the etiology of familial superior oblique palsy.
PMID: 19822909 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Kim JH, Hwang JM Tags: Br J Ophthalmol Source Type: journals
Change of Choroidal Nevi during Five Years Follow-Up. The Beijing Eye Study.
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CONCLUSIONS: Adult Chinese with an age of 40+ years show an enlargement of presumed choroidal nevi in only a small percentage of subjects during a follow-up of 5 years. Taking into consideration that most of the study participants were already past the age of the highest risk of developing a uveal melanoma in Chinese, the results may suggest a low risk of growth of choroidal nevi into malignant choroidal melanomas in Chinese.
PMID: 19822910 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: You QS, Xu L, Jonas JB, Wang S, Yang H Tags: Br J Ophthalmol Source Type: journals
Thirty months prospective study on the treatment of retinoblastoma in Gabriel Toure Bamako Mali: 55 cases.
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CONCLUSION: The mortality associated to Retinoblastoma remains high in our regions because diagnosis is always late and it is difficult to follow-up the patients. Education and raising the awareness of both population and health workers would improve the survival rate of patients with retinoblastoma in Africa.
PMID: 19822911 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - October 11, 2009 Category: Opthalmology Authors: Togo B, Sylla F, Traoré F, Sylla M, Dicko-Traoré F, Sidibé T, Diakité AA, Keïta MM Tags: Br J Ophthalmol Source Type: journals
