The Brown University Psychopharmacology Update 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Antidepressants and extrapyramidal symptoms
The newer non ‐tricyclic antidepressants have occasionally been associated with development of extrapyramidal symptoms (EPSs). However, no large‐scale epidemiological or observational studies have examined this reported association. Recognizing the need to evaluate further the association between antidepressa nt use and extrapyramidal reactions in clinical practice settings, investigators conducted a pharmacoepidemiological study in a large cohort. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Authors: Y. W. Francis Lam Tags: Drug ‐Drug Interactions Source Type: research
Research Roundup
Subthreshold hypomanic symptoms affect antidepressant response
ECT shows efficacy in treating clozapine ‐resistant schizophrenia
Meta‐analysis: SSRIs decrease risk of myocardial infarction
Cannabidiol could help patients at high risk for psychosis
Nicotine shows promise in elderly with mood and depressive symptoms
Atypical antipsychotics compare favorably on measures of hostility
Antidepressants i n elderly generate no increased risk of dementia (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: Research Roundup Source Type: research
Antidepressant effect of ketamine requires opioid system activation
A placebo ‐controlled study in which participants with treatment‐resistant depression received naltrexone prior to infusion of ketamine found that the opioid antagonist blocked ketamine's antidepressant effects but not the dissociation induced by ketamine. These findings suggest that the antidepressant ef fect of ketamine requires activation of the opioid system. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: What's New in Research Source Type: research
No increased risk of malformations in infants exposed to quetiapine in utero
A study based on data from a reproductive safety database has found no increased risk of major malformations in infants exposed to quetiapine during early pregnancy, compared with unexposed infants whose mothers had a psychiatric illness history. These results are consistent with previous findings suggesting no strong association between fetal exposure to atypical antipsychotics and increases in the prevalence of major malformations. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: What's New in Research Source Type: research
Research supports methylphenidate for ADHD in youths, amphetamines in adults
Findings from a comprehensive systematic review and meta ‐analysis of medications to treat attention‐deficit/hyperactivity disorder (ADHD) support methylphenidate as the first‐choice option for the treatment of children and amphetamines as the preferred choice in adults. The findings apply to short‐term treatment with the medications over 12 weeks , as the researchers did not reach conclusive findings for 26‐ and 52‐week timepoints because of a scarcity of data. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: ADHD Treatment Source Type: research
Prazosin study finds reduction in quantity, not frequency, of alcohol use
A 12 ‐week double‐blind study involving individuals with alcohol use disorder has found that the alpha‐1 adrenergic receptor antagonist prazosin reduced the likelihood of heavy drinking relative to placebo. Prazosin did not reduce the frequency of drinking as measured by the number of drinking days per week. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: Substance Use Treatment Source Type: research
Your Medication Information
The Brown University Psychopharmacology Update, Volume 29, Issue 12, Page 1-2, December 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - November 14, 2018 Category: Psychiatry Tags: Supplement Source Type: research
Venlafaxine and antihypertensive drugs
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 2-2, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Authors: Y. W. Francis Lam Source Type: research
SSRIs in the medical subspecialty clinic: Part two
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 7-7, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Authors: Lawrence H. Price Source Type: research
MAT for alcohol improves clinical outcomes in patients with co ‐occurring disorders
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 3-3, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
Medications for substance use disorders lower risk of crime, suicidal behavior
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 1-6, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
Escitalopram lowers risk of cardiac events in patients with acute coronary syndrome
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 1-5, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
Research Roundup
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 6-8, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
Suicidality rare as adverse effect of antidepressants
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 4-4, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
Your Medication Information
The Brown University Psychopharmacology Update,Volume 29, Issue 11, Page 1-2, November 2018. (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - October 9, 2018 Category: Psychiatry Source Type: research
