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Root coverage technique with enamel matrix derivative.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF+EMD) and connective tissue graft in combination with EMD (CTG+EMD). Case 1: The patient was a 25-year-old woman referred to Suidobashi Hospital, Tokyo Dental College for root coverage surgery on the lower right first premolar. Gingival recession was classified as Miller Class II, as no alveolar bone loss or loss of attachment was observed in the interdental area, although recession had progressed to the mucogingival junction. The patient was diagnosed with local gingival recession caused by excessive tooth brushing. Pri...
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Moriyama T, Matsumoto S, Makiishi T Tags: Bull Tokyo Dent Coll Source Type: journals

Reestablishment of occlusion with prosthesis and composite resin restorations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Here, we present a case report on prosthetic reconstruction of posterior teeth and composite resin restoration of anterior teeth yielding considerable esthetic improvement, reestablishment of disocclusion guides and function. PMID: 19815996 [PubMed - in process]
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Garcia AR, Sundfeld RH, de Alexandre RS Tags: Bull Tokyo Dent Coll Source Type: journals

Relationship between oral tissue blood flow and oxygen tension in rabbit.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, there is a positive correlation between tissue blood flow and tissue oxygen tension. Changes in tissue oxygen tension should reflect the increase or decrease in tissue blood flow. PMID: 19815995 [PubMed - in process]
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Terakawa Y, Ichinohe T, Kaneko Y Tags: Bull Tokyo Dent Coll Source Type: journals

Influence of mandibular fixation method on stability of the maxillary occlusal plane after Occlusal Plane Alteration.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study included 16 patients diagnosed with mandibular protrusion. Alteration of the occlusal plane was achieved by clockwise rotation of the maxilla by Le Fort I osteotomy and mandibular setback was performed by bilateral sagittal split ramus osteotomy. We analyzed and examined lateral cephalometric radiographs taken at 1 month, 3 months, 6 months, and 1 year after surgery. Stability achieved by two methods of mandibular fixation was compared. In one group of patients (group S) titanium screws were used, and in the other group (group P) titanium-locking mini-plates were used. No significant displacement was recognized ...
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Yosano A, Katakura A, Takaki T, Shibahara T Tags: Bull Tokyo Dent Coll Source Type: journals

Geographic distribution of postgraduate dental trainees in Japan.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, the number of dental trainees enrolled in each clinical training program and number that had actually received clinical training at each facility were compared by prefecture. The results suggest that disparities in the number of dental trainees among prefectures are being compensated for by movement across prefectural borders under the clinical training facilities-group system. Postgraduate dental trainees, however, showed a significantly greater imbalance in geographic distribution than practicing dentists. Continuation of the postgraduate clinical training for dentists under the existing system may acceler...
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Hirata S, Mataki S, Akiyama H, Nitta H, Okada M, Sakayori T, Sugito H, Ishii T Tags: Bull Tokyo Dent Coll Source Type: journals

Magnetic resonance signal intensity from retrodiscal tissue related to joint effusion status and disc displacement in elderly patients with temporomandibular joint disorders.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was carried out to explore the relationship between changes in signal intensity from retrodiscal tissue, joint fluid status and pathological disc conditions in elderly patients with TMD. Twenty patients aged over 60 years were examined. They consisted of one man and 19 women, and ranged between 60 and 79 years in age (mean, 66.0 years). The relationships between decreased signal intensity on proton-density-weighted (PDW) images and increased signal intensity on T2-weighted (T2W) MR images from retrodiscal tissue, joint fluid status and state of articular disc were examined. Joint fluid status was classified into...
Source: The Bulletin of Tokyo Dental College - May 1, 2009 Category: Dentistry Authors: Ohkubo M, Sano T, Otonari-Yamamoto M, Hayakawa Y, Okano T, Sakurai K, Sato T, Sugiyama T, Ishida R Tags: Bull Tokyo Dent Coll Source Type: journals

Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Sixty-five patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2006 were involved in this study. A search based on the SIRS diagn...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Kasahara K, Yajima Y, Ikeda C, Kamiyama I, Takaki T, Kakizawa T, Shibahara T Tags: Bull Tokyo Dent Coll Source Type: journals

Vertical fracture of mandibular condyle treated with intra-articular pumping therapy: a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a patient with vertical fracture of the mandibular condyle visualized by computed tomography (CT). A 43-year-old woman visited our department the day after the injury occurred. At the initial examination, she experienced pain in the left temporomandibular joint (TMJ) when opening her mouth. Maximum mouth opening distance was 15 mm. Routine radiography showed normal findings, but CT revealed vertical fracture of the left mandibular condyle. Based on clinical findings, conservative therapy consisting of intra-articular pumping therapy and training for mouth opening was initiated. After 10 days, mouth opening distan...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Yonezu H, Yakushiji T, Suga K, Takano N, Uchiyama T, Wakoh M Tags: Bull Tokyo Dent Coll Source Type: journals

A case of orthokeratinized odontogenic cyst suspected to be a radicular cyst.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes a case of orthokeratinized odontogenic cyst arising in the mandibular molar region of a 39-year-old man. Under the initial clinical diagnosis of radicular cyst, root canal treatment was performed on the mandibular right second molar. The treatment that continued for six months did not achieve healing. Subsequently surgical intervention was selected since the tooth fracture was found, and the prognosis was judged to be poor. After atraumatic tooth extraction, the apical cystic lesion was enucleated, and the tooth was replanted. A definite diagnosis of orthokeratinized odontogenic cyst was made by histo...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Onuki M, Saito A, Hosokawa S, Ohnuki T, Hayakawa H, Seta S, Muramatsu T, Furusawa M Tags: Bull Tokyo Dent Coll Source Type: journals

Congo red-binding protein in rough-phenotype aggregatibacter actinomycetemcomitans is amyloid-like fiber.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, therefore, we investigated amyloid formation in A. actinomycetemcomitans using a detection of CR-binding colonies on CR agar plates and CR-binding assay. All rough-phenotype strains formed dark red colonies and smooth-phenotype strains formed white or opaque red colonies on CR agar plates. Compared with smooth-phenotype strains, rough-phenotype strains showed higher CR-binding activity. CR-binding of rough-phenotype strain AKR was not affected by protease digestion or heating, whereas smooth-phenotype strain 29523 showed a marked reduction in CR-binding after both types of treatment. AKR showed amyloid-posit...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Kimizuka R, Kato T, Hashimoto S, Yamanaka-Okada A, Okuda K, Ishihara K Tags: Bull Tokyo Dent Coll Source Type: journals

Microtensile bond strength of indirect resin composite to resin-coated dentin: interaction between diamond bur roughness and coating material.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This aim of this study was to determine the effect of type of bur and resin-coating material on microtensile bond strength (microTBS) of indirect composite to dentin. Dentin surfaces were first ground with two types of diamond bur and resin-coated using UniFil Bond (UB) or Adper Single Bond (SB), and then bonded to a resin composite disc for indirect restoration with adhesive resin cement. After storage for 24 hr in distilled water at 37 degrees C, microTBS was measured (crosshead speed 1 mm/min). When UB was applied to dentin prepared using the regular-grit diamond bur, microTBS was significantly lower than that in de...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Kameyama A, Oishi T, Sugawara T, Hirai Y Tags: Bull Tokyo Dent Coll Source Type: journals

Effect of new bone substitute materials consisting of collagen and tricalcium phosphate.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to investigate the effect of new bone substitute materials consisting of collagen and tricalcium phosphate (TCP). Prior to the experiment, mandibular dog teeth were extracted. After 3 months, specific cavities were prepared on the alveolar ridge. In one group, cavities were filled with collagen sponge (CS group), in the other, cavities were filled with TCP sponge (TCP group). Cavities with no fillings (Cont group) were created as controls. Mandibular bone was evaluated histopathologically at experimental time periods of 1, 2, 4, and 8 weeks. Due to the non critical inflammatory symptoms th...
Source: The Bulletin of Tokyo Dental College - February 1, 2009 Category: Dentistry Authors: Takahashi K Tags: Bull Tokyo Dent Coll Source Type: journals

Effects of aging on mouse tongue epithelium focusing on cell proliferation rate and morphological aspects.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to investigate cell proliferation rate and certain morphological features of mouse epithelium as aging progresses. Tongue biopsies were performed on female mice (Mus domesticus domesticus) at 2, 8, 14 and 20 months of age as indicative of adolescence, adulthood, early senescence and senescence, respectively. Histological sections of tongue were stained with hematoxylin-eosin and subjected to silver staining for active nucleolar organizer region counting. Cell proliferation rate and epithelial thickness analysis were carried out. Analysis of variance detected no differences between the groups i...
Source: The Bulletin of Tokyo Dental College - November 1, 2008 Category: Dentistry Authors: Carrard VC, Pires AS, Badauy CM, Rados PV, Lauxen IS, Sant'Ana Filho M Tags: Bull Tokyo Dent Coll Source Type: journals

Patient in whom surgery was selected to improve mandible position after changing doctors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A patient who visited our department after job relocation was reexamined, and a marked discrepancy was found in mandibular position between centric occlusion and centric relation. Although the patient was originally scheduled to undergo orthodontic treatment only, the results of comprehensive tests indicated that surgery would be needed to resolve this discrepancy. Surgery was performed with the patient's consent, yielding favorable results. Although the entire orthodontic treatment lasted 3 years and 11 months, including treatment prior to transfer, it was clear that long-term use of intermaxillary elastics would not ...
Source: The Bulletin of Tokyo Dental College - November 1, 2008 Category: Dentistry Authors: Miyazaki H, Sueishi K, Takano M, Kakizawa T Tags: Bull Tokyo Dent Coll Source Type: journals

Effects of soft-diet feeding on BDNF expression in hippocampus of mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Our previous study showed that mice fed a soft diet after weaning had reduced synaptic connections in the hippocampal formation and impaired spatial learning ability after 3 months of age. We hypothesized that soft-diet feeding during development reduced levels of brain-derived neurotrophic factor (BDNF) protein in the hippocampus, resulting in lower synaptic densities in this region. Male pups of C57BL/6 mice were fed either a solid (hard-diet group) or powdered diet (soft-diet group), starting at weaning. Expression of BDNF protein in the hippocampus and cerebral cortex was evaluated quantitatively with enzyme-linked...
Source: The Bulletin of Tokyo Dental College - November 1, 2008 Category: Dentistry Authors: Yamamoto T, Hirayama A, Hosoe N, Furube M, Hirano S Tags: Bull Tokyo Dent Coll Source Type: journals

Expression of myosin heavy-chain mRNA in cultured myoblasts induced by centrifugal force.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we investigated the effect of stimulating cultured myoblasts with centrifugal force at different speeds on cell proliferation and myosin heavy-chain (MyHC) mRNA expression in muscle fiber. Stimulation of myoblasts was carried out at 2 different speeds for 20 min using the Himac CT6D, a desk centrifuge, and cells were observed at 1, 3 and 5 days later. Number of cells 1 and 5 days after centrifugal stimulation was significantly larger in the 62.5 x g and 4,170 x g stimulation groups than in the control group. Expression of MyHC-2b mRNA 1 day after centrifugal stimulation was significantly higher in the 2 stim...
Source: The Bulletin of Tokyo Dental College - November 1, 2008 Category: Dentistry Authors: Kurokawa K, Sakiyama K, Abe S, Hiroki E, Naito K, Nakajima K, Takeda T, Inoue T, Ide Y, Ishigami K Tags: Bull Tokyo Dent Coll Source Type: journals

Influence of light curing unit and ceramic thickness on temperature rise during resin cement photo-activation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to determine the effect of different ceramic thickness on heat generation during resin cement photo-activation by QTH (quartz-tungsten-halogen), LED (light emitting diode), and PAC (plasma arc-curing) LCUs (light curing units). The resin cement used was Rely X ARC (3M-ESPE), and the ceramic was IPS Empress Esthetic (Ivoclar-Vivadent), of which 0.7-, 1.4- and 2.0-mm thick disks, 0.8 mm in diameter were made. Temperature increase was recorded with a type-K thermocouple connected to a digital thermometer (Iopetherm 46). An acrylic resin base was built to guide the thermocouple and support the 1.0...
Source: The Bulletin of Tokyo Dental College - November 1, 2008 Category: Dentistry Authors: Guiraldo RD, Consani S, Mastrofrancisco S, Consani RL, Sinhoreti MA, Correr-Sobrinho L Tags: Bull Tokyo Dent Coll Source Type: journals

In vitro-evaluation of secondary caries formation around restoration.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this in vitro study was to evaluate demineralization around restorations. Class V preparations were made on the buccal and lingual surfaces of each tooth. TPH (Group 1), Fuji II LC (Group 2), Tetric (Group 3), Dyract (Group 4), GS 80 (Group 5) and Chelon Fil (Group 6) were randomly placed in equal numbers of teeth. The teeth were submitted to a pH-cycling model associated with a thermocycling model. Sections were made and the specimens were examined for the presence of demineralization under polarized light microscopy. Demineralization was significantly reduced with Chelon Fil (Group 6). Furthermore, a sim...
Source: The Bulletin of Tokyo Dental College - August 1, 2008 Category: Dentistry Authors: Okida RC, Mandarino F, Sundfeld RH, de Alexandre RS, Sundefeld ML Tags: Bull Tokyo Dent Coll Source Type: journals

Static MR images for diagnosis of swallowing.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Evaluation of swallowing has been made possible by cine-Magnetic resonance (MR) imaging with high time resolution. However, the spatial resolution in cine-MR imaging remains inadequate for the detection of anatomical structures. Therefore, it is necessary to refer to static MR images in conjunction with cine-MR imaging. The aim of this study was to determine which MR parameters were appropriate for static imaging of the anatomical structures involved in swallowing. MR imaging was carried out, and T1-weighted, T2-weighted and proton-density-weighted MR images were obtained in the sagittal plane in 5 healthy volunteers. ...
Source: The Bulletin of Tokyo Dental College - August 1, 2008 Category: Dentistry Authors: Ohkubo M, Sano T, Ishida R, Higaki T, Nishikawa K, Hayakawa Y, Otonari T, Yamamoto-Otonari M, Harada T, Wakoh M Tags: Bull Tokyo Dent Coll Source Type: journals

Inhibitory effect of cranberry polyphenol on cariogenic bacteria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to investigate the effect of cranberry polyphenol fraction on mutans streptococci. Hydrophobicity is an important factor in the adherence of bacteria to the tooth surface. We found that cranberry polyphenol fraction significantly decreased the hydrophobicity of Streptococcus sobrinus 6715, Streptococcus mutans MT8148R and JC2 in a dose-dependent manner (p<0.05). Biofilm formation by S. sobrinus 6715 and S. mutans MT8148R was inhibited by 100 microg/ml cranberry polyphenol fraction (p<0.01). When dosage was increased to 500 microg/ml, biofilm formation by S. mutans JC2 was significant...
Source: The Bulletin of Tokyo Dental College - August 1, 2008 Category: Dentistry Authors: Yamanaka-Okada A, Sato E, Kouchi T, Kimizuka R, Kato T, Okuda K Tags: Bull Tokyo Dent Coll Source Type: journals

Radiographic alveolar bone loss in patients undergoing periodontal maintenance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of the present cross-sectional investigation was to evaluate percentage of bone loss in patients who had been one year under periodontal maintenance at the Department of Periodontology, Faculty of Dentistry, University of São Paulo by radiographic analysis. Complete sets of periapical radiographs provided data regarding percentage of alveolar bone loss, which was correlated with arches, tooth group and proximal sites. The sample consisted of 27 men and 53 women ranging in age from 16 to 85 years (mean: 48.3 years). A total of 1,120 periapical radiographs (1,970 teeth) were digitized and analyzed with the I...
Source: The Bulletin of Tokyo Dental College - August 1, 2008 Category: Dentistry Authors: Fukuda CT, Carneiro SR, Alves VT, Pustiglioni FE, De Micheli G Tags: Bull Tokyo Dent Coll Source Type: journals

Treatment of Intrabony Periodontal Defects with Enamel Matrix Derivative in Private Practice: A Long-term Retrospective Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, EMD treatment of intrabony osseous defects yielded clinically favorable responses. The gain in clinical attachment can be longitudinally maintained in a private practice setting. Further controlled studies are needed to elucidate the clinical significance of EMD treatment. PMID: 18776720 [PubMed - in process]
Source: The Bulletin of Tokyo Dental College - May 1, 2008 Category: Dentistry Authors: Saito A, Nanbu Y, Nagahata T, Yamada S Tags: Bull Tokyo Dent Coll Source Type: journals

Detection of microsatellite alterations in plasma DNA of malignant mucosal melanoma using whole genome amplification.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malignant mucosal melanoma (MMM) still has the poorest prognosis. There is a paucity of molecular biological studies on MMM of the head and neck. We investigated free-circulating DNA microsatellites with loss of heterozygosity (LOH) in the blood of MMM patients. Cancer-related DNA is found in plasma, with cancer patients showing a higher level of free-circulating DNA than normal subjects. However, it is difficult to obtain sufficient amounts of such DNA for PCR analysis. We have searched for ways to improve all stages of such research, and detected new microsatellite alterations by triplicated whole genome amplificatio...
Source: The Bulletin of Tokyo Dental College - May 1, 2008 Category: Dentistry Authors: Nakamoto D, Yamamoto N, Takagi R, Katakura A, Mizoe JE, Shibahara T Tags: Bull Tokyo Dent Coll Source Type: journals

Three-dimensional Relationship between Pharyngeal Airway and Maxillo-facial Morphology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, to clarify the influence of the maxillo-mandibular bones and cranium on airway morphology, maxillo-facial morphology in patients with jaw deformation was measured using cephalograms and X-ray CT imaging data. Subjects consisted of 25 adult women in whom cephalograms and X-ray CT were taken to diagnose jaw deformation. The data obtained were classified based on skeletal and facial patterns according to Ricketts analysis, and changes in internal diameter, height and volume of the middle pharyngeal airway were observed. The results showed that the internal diameter of the inferior airway expanded anteriorly whe...
Source: The Bulletin of Tokyo Dental College - May 1, 2008 Category: Dentistry Authors: Kikuchi Y Tags: Bull Tokyo Dent Coll Source Type: journals

Longitudinal Study on Influence of Prolonged Non-nutritive Sucking Habits on Dental Caries in Japanese Children from 1.5 to 3 Years of Age.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of the present study was to investigate the relationship between infant sucking habits and the prevalence of caries in Japanese preschool children.The study was designed as a prospective, longitudinal study starting with 592 children aged 18 months. Information on sucking habits and patterns of feeding was collected from parents in the form of a questionnaire. Children who continued breastor bottle-feeding at 18 months of age were eliminated prior to the evaluations. The children were divided into 3 groups according to their sucking habits at 18 months of age: Group 1: children with a finger-sucking habit (...
Source: The Bulletin of Tokyo Dental College - May 1, 2008 Category: Dentistry Authors: Yonezu T, Yakushiji M Tags: Bull Tokyo Dent Coll Source Type: journals

Relationship between Function of Masticatory Muscle in Mouse and Properties of Muscle Fibers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study revealed that muscles with different roles function comprehensively during complicated masticatory movement. PMID: 18776716 [PubMed - in process]
Source: The Bulletin of Tokyo Dental College - May 1, 2008 Category: Dentistry Authors: Abe S, Hiroki E, Iwanuma O, Sakiyama K, Shirakura Y, Hirose D, Shimoo Y, Suzuki M, Ikari Y, Kikuchi R, Ide Y, Yoshinari M Tags: Bull Tokyo Dent Coll Source Type: journals

Clinical survey on type of restoration in deciduous teeth.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was conducted in 533 children with 1,634 treated teeth who visited the Pediatric Dentistry Department at the Chiba Hospital of Tokyo Dental College between January and December, 2003. Restorations on deciduous tooth were categorized by age of patient and tooth type. The following observations were made: Children aged 4 (17.9%) visited the clinic most frequently and this group had the highest number of deciduous restorations (21.3%). Among the 1,634 deciduous teeth restored, metal inlays were provided in 29.4% of total teeth restored, composite resin restorations in 27.2%, stainless-steel crowns in 25.7%, composi...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Fukuyama T, Oda S, Yamashita H, Sekiguchi H, Yakushiji M Tags: Bull Tokyo Dent Coll Source Type: journals

Clinical statistical investigation of cleft lip and palate patients aged over 18 years at Department of Orthodontics, Suidobashi Hospital, Tokyo Dental College.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since the fee for orthodontic treatment of malocclusion caused by cleft lip and palate (CLP) became covered by national health insurance in 1982, orthodontic treatment from school age has become the norm. However, in some CLP patients, orthodontic treatment is commenced in adulthood. A number of studies have reported on orthodontic treatment in adult CLP patients. The purpose of this study was to clarify the number and age of new patients, chief complaint, referral status, cleft type, malocclusion, history of orthodontic treatment, and acceptance and planning of orthodontic treatment. The study investigated new CLP pat...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Sakamoto T, Sueishi K, Miyazaki H, Katada H, Ebihara T, Kosaka T Tags: Bull Tokyo Dent Coll Source Type: journals

Clinical training in department of general dentistry at Tokyo Dental College Chiba Hospital.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the training curriculum of this course. PMID: 18580049 [PubMed - in process]
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Sugiyama T, Tsunoda M, Takahashi T, Yamakura D, Miyashita YK, Adachi R, Morinaga K, Itou A, Haruyama C, Takeda T, Nakajima K Tags: Bull Tokyo Dent Coll Source Type: journals

Long-term observation of porous sapphire dental implants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We used porous sapphire dental implants made of alumina clinically for 4 years 1 month, commencing September, 1984 until September, 1988. Subjects consisted of 18 men and 42 women 20-71 years old (mean age: 35 years). Sixty-five implants were inserted in 60 patients. Of these, 20 were clinical cases of an implant connected with natural teeth and 45 were free-standing cases. We conducted a follow-up study on these patients over a 23-year period. One implant in 1 patient had to be removed because of postoperative infection and 8 implants in 7 patients had to be removed because of fracturing or detachment of the porous-pa...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Takahashi T, Sato T, Hisanaga R, Miho O, Suzuki Y, Tsunoda M, Nakagawa K Tags: Bull Tokyo Dent Coll Source Type: journals

Curvature of cervical vertebra in 8020 achievers observed by lateral cephalogram.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The hypothesis of this research was that elderly people with many remaining teeth and good occlusion (8020 achievers) would be able to maintain proper head and body posture, despite aging. The purpose of this study, as a first stage, was to clarify the aging phenomenon of cervical curvature in 8020 achievers in comparison with that in young adults. Subjects consisted of twenty-eight 8020 achievers, with a mean age of 82.96+/-3.3 years and 26.5+/-4.0 teeth. For comparison, forty adults in their 20's with a mean age of 22.9+/-0.7 years and 28.2+/-0.6 teeth were also enrolled. The cervical vertebra was assessed based on t...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Tahara R, Motegi E, Nomura M, Tsuchiya Y, Shino T, Inoue E, Sueishi K, Matsuda I Tags: Bull Tokyo Dent Coll Source Type: journals

Awareness of malalignment and malocclusion in children and their guardians.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We conducted a survey on the awareness of abnormalities of dentition and occlusion in 1,904 children (0-15 years old) and their guardians (parents, grandmothers, grandfathers and siblings) on their initial visit to the Department of Pediatric Dentistry, Chiba Hospital, Tokyo Dental College. The location and type of abnormality for which the children and their guardians most commonly sought treatment were crowding of the upper and lower anterior teeth and inverted occlusion. The most common initial triggers for concern were "guardians noticed abnormalities themselves". It seems logical that where malocclusions that chil...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Yamashita H, Yotsuya K, Takeuchi T, Oda S, Hara A, Sekiguchi H, Yakushiji M Tags: Bull Tokyo Dent Coll Source Type: journals

Development of computer-based OSCE re-examination system for minimizing inter-examiner discrepancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The validity of objective structured clinical examination (OSCE) in evaluating clinical skills has been confirmed in a number of studies. However, inter-examiner reliability has been noted as a concern by many educators. To minimize discrepancy between examiners, in application of the OSCE, we have developed an OSCE attitude and skill test re-examination system. Student performance was digitally, filmed and stored as electronic files. When results showed inter-examiner discrepancy, those items were automatically extracted in the form of a re-examination sheet to allow student re-evaluation by a third examiner in refere...
Source: The Bulletin of Tokyo Dental College - February 1, 2008 Category: Dentistry Authors: Abe S, Kawada E Tags: Bull Tokyo Dent Coll Source Type: journals

Comparison of salivary cytokine levels in oral cancer patients and healthy subjects.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to find informative salivary biomarkers specific to oral cancer we examined expression of 4 kinds of cytokine in saliva. Levels of interleukins (IL-1beta, -6, -8) and osteopontin were measured by ELISA using whole saliva samples collected from 19 patients with oral cancer (9 men, 10 women; mean age, 60.9 years) and 20 healthy persons (15 men, 5 women; mean age, 32 years). Expression of the 4 cytokines was higher in patients with oral cancer than in healthy controls. The difference was significant in IL-6, in particular. The results suggest that saliva offers a potential target for a screening test aimed at det...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Katakura A, Kamiyama I, Takano N, Shibahara T, Muramatsu T, Ishihara K, Takagi R, Shouno T Tags: Bull Tokyo Dent Coll Source Type: journals

Osteoma of mandibular condyle as cause of acute pain and limited-mouth-opening: case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In benign tumors in the mandibular condyle such as osteoma and osteochondroma, symptoms such as pain and limited-mouth-opening are rarely observed. Therefore, these tumors are often detected after the development of changes in occlusion and mandibular midline deviation. We encountered a very rare patient with mandibular condyle osteoma who showed acute pain and markedly limited-mouth-opening. PMID: 18360106 [PubMed - indexed for MEDLINE]
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Yonezu H, Wakoh M, Otonari T, Sano T, Hashimoto S, Uchiyama T Tags: Bull Tokyo Dent Coll Source Type: journals

Nasolabial flap reconstruction of floor of mouth.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We treated two patients requiring nasolabial flap reconstruction. The first patient was a 75-year-old man with mucoepidermoid carcinoma in the left-side floor of the mouth; requiring resection of the floor of the mouth, partial mandibulectomy, and left supraomohyoid neck dissection. The second patient was a 74-year-old man with recurrent acinic cell carcinoma in the anterior oral floor infiltrating as far as the mandible. This patient required wide excision of the anterior part of the oral cavity, including amputation of the mandible. After tumor resection, both cases had a nasolabial flap reconstruction. The postopera...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Ikeda C, Katakura A, Yamamoto N, Kamiyama I, Shibahara T, Onoda N, Tamura H Tags: Bull Tokyo Dent Coll Source Type: journals

Genetic effects of X-ray and carbon ion irradiation in head and neck carcinoma cell lines.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The effects of X-ray and carbon ion irradiation on DNA and genes in head and neck carcinoma cells were examined. Four head and neck cancer cell lines (squamous cell carcinoma, salivary gland cancer, malignant melanoma, normal keratinocyte) were treated with 1, 4, and 7 GyE of carbon ion, or 1, 4, and 8 Gy of X-ray, respectively. DNA and RNA in the treated cells were extracted and purified. PCR-LOH (polymerase chain reaction-loss of heterozygosity) analysis with 6 microsatellite regions on chromosome 17 was performed to determine DNA structural damage, and then microarray analysis was performed to reveal changes in gene...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Yamamoto N, Ikeda C, Yakushiji T, Nomura T, Katakura A, Shibahara T, Mizoe JE Tags: Bull Tokyo Dent Coll Source Type: journals

Tooth axis and skeletal structures in mandibular molar vertical sections in jaw deformity with facial asymmetry using MPR images.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of the present study was to investigate frontal morphological asymmetry in the mandibular molar region in terms of tooth axis and skeletal structures using vertical MPR sections in jaw deformity accompanied by facial asymmetry. Subjects consisted of 15 patients with jaw deformity accompanied by facial asymmetry aged 17.4 years to 37.8 years. There were four men and eleven women. Based on X-ray computed tomography (CT) scans, DICOM viewer software was used to prepare multiplanar reconstruction (MPR) sections. The mandible was then positioned on a reference plane based on the menton and left and right gonions, ...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Nojima K, Yokose T, Ishii T, Kobayashi M, Nishii Y Tags: Bull Tokyo Dent Coll Source Type: journals

Course of fracture line in sagittal splitting of human mandible.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We performed sagittal splitting osteotomy using fresh, unfixed cadavers. Observation was carried out macroscopically and with light microscopy and 3-dimensionally reconstructed images. The aim of this study was to clarify the relationship between the fracture line and the Haversian canal and Haversian lamellae. Macroscopic observation revealed that the fracture line run through the mandibular angle from the inferior rim of the mandibular ramus towards the posterior rim, passing almost through the center of the ridgeline. Histological observation showed that the fracture line tended to run along the curve of the lamella...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Hanaue K, Katakura A, Kasahara K, Kamiyama I, Takaki T, Shibahara T, Abe S, Ide Y Tags: Bull Tokyo Dent Coll Source Type: journals

Cellular mechanisms in taste buds.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the soft palate, tongue, pharynx and larynx surrounding the oral region, taste buds are present, allowing the sensation of taste. On the tongue surface, 3 kinds of papillae are present: fungiform, foliate, and circumvallate. Approximately 5,000 taste buds cover the surface of the human tongue, with about 30% fungiform, 30% foliate and 40% circumvallate papillae. Each taste bud comprises 4 kinds of cells, namely high dark (type I), low light (type II), and intermediate (type III) cells in electron density and Merkel-like taste basal cells (type IV) located at a distance from taste pores. Type II cells sense taste sti...
Source: The Bulletin of Tokyo Dental College - November 1, 2007 Category: Dentistry Authors: Suzuki T Tags: Bull Tokyo Dent Coll Source Type: journals

Age-related differences in expression of vascular endothelial growth factor by periodontal ligament cells in vitro.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the data revealed that PDL cells varied with age, and suggest that in view of such changes in cell proliferation and VEGF mRNA expression, age should be taken into consideration in periodontal treatment. PMID: 18057861 [PubMed - indexed for MEDLINE]
Source: The Bulletin of Tokyo Dental College - August 1, 2007 Category: Dentistry Authors: Matsuzaka K, Tsuruoka M, Kokubu E, Katakura A, Endo T, Shibukawa Y, Shintani M, Tazaki M, Ishihara K, Hashimoto S, Yoshinari M, Inoue T Tags: Bull Tokyo Dent Coll Source Type: journals

Dental care for physically or mentally challenged at public dental clinics.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recently, local administration bureaus have established a number of dental clinics and centers for the physically or mentally challenged (PMC) in collaboration with local dental associations. The aim of this study was to investigate dental treatment and general supportive care for the PMC in dental clinics in Tokyo. A dental clinic for the PMC located in northwestern Tokyo in a district with a population of about 680,000 was selected for the study. The variables studied based on dental records included total number of patients, type of disability, medical history, systemic condition, age, treatment regimen and type of ...
Source: The Bulletin of Tokyo Dental College - August 1, 2007 Category: Dentistry Authors: Mochizuki K, Tsujino K, Ohtawa Y, Yakushiji M, Nomura K, Ichinohe T, Kaneko Y Tags: Bull Tokyo Dent Coll Source Type: journals

Study on internal structure of zygomatic bone using micro-finite element analysis model--differences between dentulous and edentulous dentition in Japanese cadavers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The purpose of this study was to analyze changes in the internal structure of zygomatic bone using a micro-finite element analysis model (muFEA) and compare angular orientation of trabeculae against compressive force in edentulous and dentulous jaws. Twenty zygomatic bones from dentulous jaws and 20 zygomatic bones from edentulous jaws harvested from Japanese male cadavers were used. From 2-dimensional slice images, we reconstructed 3-dimensional (3D) structure by the volume rendering method using micro-computed tomography (micro-CT). To analyze mechanical properties, all voxels were converted to muFEA models. The angl...
Source: The Bulletin of Tokyo Dental College - August 1, 2007 Category: Dentistry Authors: Yoshino M, Kato Y, Kizu Y, Tonogi M, Abe S, Ide Y, Yamane GY Tags: Bull Tokyo Dent Coll Source Type: journals

Estimation of optimal amount of fluoride dentifrice for adults to prevent caries by comparison between fluoride uptake into enamel in vitro and fluoride concentration in oral fluid in vivo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the relationship between fluoride uptake into the surface layer (4-6 microm)of enamel and the active fluoride concentration in vitro and the relationship between the amount of fluoride dentifrice (1,000 ppmF) used and the fluoride concentration in oral fluid in vivo. It became clear that fluoride uptake into the enamel was increased at the concentrations of 300 ppmF or more. Fluoride uptake at 300 ppmF was increased for 2 min and became saturated thereafter. The results of the relationship between the fluoride concentration in the oral fluid and the amount of fluoride dentifrice used indicated that the amount o...
Source: The Bulletin of Tokyo Dental College - August 1, 2007 Category: Dentistry Authors: Koga H, Yamagishi A, Takayanagi A, Maeda K, Matsukubo T Tags: Bull Tokyo Dent Coll Source Type: journals

Loss of heterozygosity (LOH) on chromosomes 2q, 3p and 21q in Indian oral squamous cell carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Around the world, 200,000 people a year are affected by oral cancer, and the incidence of this disease is 10 times higher in India than Japan, mainly due to the custom of chewing tobacco. Loss of heterozygosity (LOH) on the long arm of chromosome 2 (2q), the short arm of chromosome 3 (3p) and the long arm of chromosome 21 (21q) are observed in several human cancers. We identified novel tumor suppressor loci on these regions in primary oral squamous cell carcinomas (OSCCs) in Japanese. However, there has been no detailed analysis of LOH on these chromosomes in Indians. In the present study, we investigated LOH at 2q, 3p...
Source: The Bulletin of Tokyo Dental College - August 1, 2007 Category: Dentistry Authors: Yamamoto N, Kuroiwa T, Katakura A, Shibahara T, Choudhury C Tags: Bull Tokyo Dent Coll Source Type: journals

Dental implant treatment with different techniques for sinus floor elevation--a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 60-year-old man with missing maxillary molar teeth received dental implant therapy for reconstruction of occlusion. Sinus floor elevation with autogenous bone graft consisting of iliac bone block and particulate cancellous bone and marrow (PCBM) was performed in the bilateral maxillary sinuses for implant placement. On the right side, bone height in the molar region was less than 2mm. Therefore, a delayed protocol was applied, and 2 implants were placed 4 months after bone grafting. Bone graft resorption occurred during the healing period of 4 months. On the left side, 3 implants were placed simultaneously with sinus...
Source: The Bulletin of Tokyo Dental College - May 1, 2007 Category: Dentistry Authors: Sekine H, Taguchi T, Seta S, Takano M, Takeda T, Kakizawa T Tags: Bull Tokyo Dent Coll Source Type: journals

Dentofacial growth in patients with Sotos syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we evaluated changes in maxillofacial growth in 2 patients with cerebral gigantism during the peripubertal period. Patient 1 was a boy aged 8 years at the first examination. The face showed midface retraction and a tapered mandible. Maxillary median diastema with an OJ of 2.5 mm and OB of 1.0 mm was observed, and the molar region showed mandibular mesial occlusion. Radiography revealed a lack of 15, 25, 37, 47, 14, 24, 34 and 44. Cephalometrics demonstrated maxillary and mandibular retrusion with an SNA of 68 degrees and an SNB of 70 degrees , and the patient had leptoprosopia with a mandibular plane of 38.0...
Source: The Bulletin of Tokyo Dental College - May 1, 2007 Category: Dentistry Authors: Takei K, Sueishi K, Yamaguchi H, Ohtawa Y Tags: Bull Tokyo Dent Coll Source Type: journals

Case of recurrent paracoccidioidomycosis in female. 10 years after initial treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes a case of recurrence of chronic paracoccidioidomycosis 10 years following the initial diagnosis. A 56-year-old female was admitted to the Dental Clinic of the Pontifical Catholic University of Paraná complaining of oral soreness. Mulberry-like ulcerations were observed on the gingiva, right labial comissura, and vermillion of the lip. The patient reported persistent chronic cough, weight loss, appetite loss and fever. The anamnesis revealed that the patient had developed and been treated for paracoccidioidomycosis 10 years earlier. A biopsy was performed and microscopic examination revealed micro...
Source: The Bulletin of Tokyo Dental College - May 1, 2007 Category: Dentistry Authors: De Azevedo Izidoro AC, Da Silva PC, De Oliveira Ribas M, De Azevedo LR, Machado MA, De Lima AA Tags: Bull Tokyo Dent Coll Source Type: journals

Pressure on anterior region of palate during thumb-sucking.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Measurement of the pressure applied to the anterior region of the palate and incisor region of the mandible during thumb-sucking was carried out 3 female children. A polyethylene bag embedded with a high-sensitivity small pressure sensor was fixed on the ventral side of the thumb so that the baroreceptor could be interposed between the thumb and palate during thumb-sucking. The children were allowed to perform habitual thumb-sucking, and the resulting pressure signals were detected with a high-response dynamic strainmeter and recorded. Measured peak pressures were about 2-4.5 kgw, with large individual variation, and w...
Source: The Bulletin of Tokyo Dental College - May 1, 2007 Category: Dentistry Authors: Yokota R, Mishiro M, Abe T, Miyake A, Shiina N, Sueishi K, Yamaguchi H Tags: Bull Tokyo Dent Coll Source Type: journals

Effect of cevimeline on radiation-induced salivary gland dysfunction and AQP5 in submandibular gland in mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to clarify the effects of the muscarinic receptor agonist, cevimeline, on saliva flow and expression of aquaporin5 (AQP5) in submandibular gland after X-ray irradiation. Using a previously established radiation-induced xerostomia model mouse, saliva flow from at 7 days before irradiation to at 28 days after irradiation was investigated in mice that were treated with cevimeline before or after irradiation. Radiation caused a significant decrease in saliva flow compared with nonirradiated salivary glands. Cevimeline post-treatment also caused a significant decrease in saliva flow. In contrast, c...
Source: The Bulletin of Tokyo Dental College - May 1, 2007 Category: Dentistry Authors: Takakura K, Takaki S, Takeda I, Hanaue N, Kizu Y, Tonogi M, Yamane GY Tags: Bull Tokyo Dent Coll Source Type: journals