Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations
ConclusionThe different imaging manifestations of mucinous adenocarcinoma are possibly due to the different amounts or viscosity of mucus produced, and the mechanisms of its formation may include (1) tumour cells in different shapes have different abilities to produce mucus; (2) tumours in different stages produce different amounts or viscosity of mucus; and (3) the TTF-1 and ALK genes affect the production of mucus. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 15, 2024 Category: Respiratory Medicine Authors: Jun Han,
Jie Gao,
Demei Chen,
Mou Du,
Yuxin Wu,
Xidong Ma,
Mei Xie,
Hua Han,
Chongchong Wu,
Xinying Xue Tags: ORIGINAL ARTICLE Source Type: research
Prognostic factors and predictive models for patients with lung large cell neuroendocrine carcinoma: Based on SEER database
ConclusionsThe nomogram obtained from our study is expected to be a useful tool for personalized prognostic prediction of LCNEC patients, which may help in clinical decision-making. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 13, 2024 Category: Respiratory Medicine Authors: Wenqiang Li,
Qian Huang,
Xiaoyu He,
Qian He,
Qun Lai,
Quan Yuan,
Zhiping Deng Tags: ORIGINAL ARTICLE Source Type: research
The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non ‐small cell lung cancer: A meta‐analysis
ConclusionsPersistence of the T790M gene mutation after the development of Osimertinib resistance is associated with higher therapeutic benefits of Osimertinib in NSCLC patients. The results of tissue detection are more significant than those of plasma detection. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 8, 2024 Category: Respiratory Medicine Authors: Liuxian Guo,
Guojin Zhou,
Min Huang,
Kejing Tang,
Jing Xu,
Jie Chen Tags: REVIEW ARTICLE Source Type: research
Efficacy of immune checkpoint inhibitors in advanced non ‐small cell lung cancer patients with KRAS mutations: A network meta‐analysis
ConclusionOur analysis found that among advanced NSCLC patients withKRAS gene mutations, first-line treatment with pembrolizumab alone demonstrated greater efficacy. Similarly, second-line treatment with nivolumab alone was found to be more effective in this patient population. However, the sample size of this study was limited, Therefore, additional clinical data is necessary to validate this finding in subsequent research. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2024 Category: Respiratory Medicine Authors: Lin Zhang,
Wei Chen,
Hongtao Wei,
Junxian Yu Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Radiological and clinical features of large consolidative ‐type pulmonary invasive mucinous adenocarcinoma
ConclusionHalo, vacuole, angiogram, and dead branch signs were frequently observed in consolidative-type IMA. Kirsten rat sarcoma viral oncogene mutations are common in consolidative-type IMA, especially site G12V, whereas epidermal growth factor receptor mutations were rare; therefore, gene immunotherapy was more difficult. Most patients were in stage T3 –T4; however, lymph node metastasis was rare. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 27, 2024 Category: Respiratory Medicine Authors: Jiaqi Chen,
Linlin Qi,
Jianwei Wang,
Liyan Xue,
Qi Xue,
Jia Jia,
Guochao Zhang,
Jianing Liu,
Fenglan Li,
Shulei Cui Tags: ORIGINAL ARTICLE Source Type: research
Pleural fluid characteristics of patients with COVID ‐19 infection
ConclusionWe demonstrate that 68.5% of pleural effusions in patients with COVID-19 infection were exudative and hypothesize that COVID-19-associated pleural effusions are likely to be exudative with WBC differential more likely to be predominantly lymphocytic. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 26, 2024 Category: Respiratory Medicine Authors: Ryan A. Denu,
Victoria Forth,
Majid Shafiq Tags: BRIEF REPORT Source Type: research
Clinical comparison of HMPV and RSV infections in hospitalised Malaysian children: A propensity score matched study
ConclusionhMPV and RSV infections in children share similar clinical manifestations and outcomes, with hMPV affecting older children and showing higher corticosteroid usage. These findings emphasise the need for equal clinical vigilance for both hMPV and RSV in paediatric respiratory infections. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 26, 2024 Category: Respiratory Medicine Authors: David Chun ‐Ern Ng,
Chuin‐Hen Liew,
Kah Kee Tan,
Elida Hanan binti Awang,
Farah Nuruliayana binti Ahmad Nazri,
Asuwani K. Tamil Maran,
Vishnu Arvindran a/l Chandra Mohan,
Durairaaj Ramachandran,
Michelle Chok,
Cheah Hooi Teh,
Airena Mohamad Tags: ORIGINAL ARTICLE Source Type: research
Value of rapid on ‐site evaluation combined with interventional pulmonology techniques in the diagnosis of pulmonary cryptococcosis
ConclusionROSE has commendable accuracy and timeliness, and CT-PNB offers further advantages in this regard. ROSE enhances the diagnostic efficiency of EBUS-TBLB for PC and is safe and effective. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 26, 2024 Category: Respiratory Medicine Authors: Jiaqi Cao,
Rong Zhou,
Qian He,
Ming Zhang,
Chunlai Feng Tags: ORIGINAL ARTICLE Source Type: research
SOX ‐1 antibodies positive Lambert–Eaton myasthenic syndrome with occult small cell lung cancer: A case report
We report a patient with LEMS who was tested positive for SOX-1 antibodies and was definitively diagnosed with SCLC by pathological biopsy after 10 months follow-up. AbstractLambert –Eaton myasthenic syndrome (LEMS) is a rare paraneoplastic neurological syndrome of the neuromuscular transmission. The symptoms often progress slowly and can be misdiagnosed in early stage. Seropositive SOX-1 antibodies are support for the diagnosis of LEMS and have high specificity for small cel l lung cancer (SCLC). In this paper, we report a case of a 56-year-old man with smoking history who was admitted to hospital with progressive mus...
Source: The Clinical Respiratory Journal - March 19, 2024 Category: Respiratory Medicine Authors: Liming Zhao,
Hongyan He,
Weixin Han,
Yizhe Meng,
Lifei Kang,
Yanqiang Chen Tags: BRIEF REPORT Source Type: research
Primary pulmonary histiocytic sarcoma with high PD ‐L1 expression benefited from immunotherapy: A case report and bioinformatic analysis
This may be the first reported case with high PD-L1 expression in primary pulmonary histiocytic sarcoma who may benefit from immunotherapy. Routine PD-L1 expression detection is recommended for histiocytic sarcoma patients especially those who got advanced cancer. Patients with high PD-L1 expression in primary pulmonary histiocytic sarcoma may benefit from immunotherapy such as nivolumab and pembrolizumab significantly and safely. AbstractHistiocytic sarcoma is an aggressive haematopoietic malignancy accounting for less than 1% of haematolymphoid neoplasms with a diagnosis based on morphology and immunophenotype of tissue ...
Source: The Clinical Respiratory Journal - March 7, 2024 Category: Respiratory Medicine Authors: Yuanjie Lin,
Qian Cao,
Aonan Hong,
Xiao Liang Tags: ORIGINAL ARTICLE Source Type: research
Pulmonary scedosporiosis in an intractable immunocompetent host: A case report and literature review
In this report, we present a case of localized pulmonary scedosporiosis in an immunocompetent patient and analyze a total of 25 immunocompetent patients with pulmonary scedosporiosis. Through this case and the literature, we highlight the importance of considering pulmonary scedosporiosis in patients with nonspecific clinical symptoms and radiological findings resembling aspergilloma. This case and the literature further emphasize the significance of surgical intervention. Regardless of the use of antifungal drugs, surgery should be conducted as soon as possible. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 4, 2024 Category: Respiratory Medicine Authors: Hong Yu Liang,
Chun Hua Han,
Wen Juan Xu,
Jian Sun,
Qiang Wang Tags: REVIEW ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 4, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
The inhibitory effect of apatinib on different small cell lung cancer cells and in lung cancer ‐bearing mice and patients
ConclusionApatinib has a significant inhibitory effect on small cell lung cancer with high expression of VEGFR2 and may be a treatment for small cell lung cancer patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 26, 2024 Category: Respiratory Medicine Authors: Mingtao Liu,
Hui Li,
Ranran Guo,
Xia Yu,
Yu Li Tags: ORIGINAL ARTICLE Source Type: research
Efficacy of airway stenting and nasogastric tube insertion in airway –esophageal fistula patients with airways compromised by advanced malignancy
ConclusionIn airway-compromised AEF patients, airway stents and nasogastric tubes are probably the preferred treatments. Airway stenting is tolerable, and routine weekly poststent bronchoscopy is needed in the first month and depending on respiratory symptoms thereafter. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 14, 2024 Category: Respiratory Medicine Authors: Xue Wu,
Guangbing Lu,
Lin cheng Luo,
Hailong Wei,
Qun Yi,
Wei Luo Tags: ORIGINAL ARTICLE Source Type: research
