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Serial in vivo imaging of the porcine heart after percutaneous, intramyocardially injected 111In-labeled human mesenchymal stromal cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  This pilot trial aimed to investigate the utilization of 111In-labeling of mesenchymal stromal cells (MSC) for in vivo tracking after intramyocardial transplantation in a xenotransplantation model with gender mismatched cells. Human male MSC were expanded ex vivo and labeled with 111In-tropolone. Ten female pigs were included. The labeled cells were transplanted intramyocardially using a percutaneous injection system. The 111In activity was determined using gamma camera imaging. Excised hearts were analyzed by fluorescence in situ hybridization (FISH) and microscopy. Gamma camera imaging revealed foc...
Source: The International Journal of Cardiovascular Imaging - November 18, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Prospective helical acquisition for coronary CT angiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Editorial CommentDOI 10.1007/s10554-009-9530-6Authors Marc Dewey, Freie Universität, Humboldt-Universität zu Berlin Department of Radiology, Charité, Medical School Berlin Germany Journal The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)Online ISSN 1573-0743Print ISSN 1569-5794 (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 18, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Tissue characterization in Takotsubo cardiomyopathy; a valuable approach?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Editorial CommentDOI 10.1007/s10554-009-9534-2Authors E. E. van der Wall, Leiden University Medical Center Leiden The Netherlands Journal The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)Online ISSN 1573-0743Print ISSN 1569-5794 (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 18, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Can a simple fingertip temperature measurement predict a cardiac event?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Editorial CommentDOI 10.1007/s10554-009-9524-4Authors Songtao Liu, Radiology and Imaging Sciences, National Institutes of Health/Clinical Center 9000 Rockville Pike, Bldg 10/ Rm 1C355 Bethesda MD 20892 USADavid A. Bluemke, Radiology and Imaging Sciences, National Institutes of Health/Clinical Center 9000 Rockville Pike, Bldg 10/ Rm 1C355 Bethesda MD 20892 USA Journal The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)Online ISSN 1573-0743Print ISSN 1569-5794 (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 12, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Signal density of left ventricular myocardial segments and impact of beam hardening artifact: implications for myocardial perfusion assessment by multidetector CT coronary angiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  We sought to explore the normal myocardial signal density (SD) levels during multidetector computed tomography coronary angiography (MDCT-CA) acquisitions and evaluated the impact of beam hardening artifacts. Background: Since myocardial perfusion by MDCT is based on the myocardial signal density (SD), it is pivotal to determine the normal values of myocardial SD and to identify potential mechanisms of misinterpretation of perfusion defects. In routine MDCT acquisitions, we commonly visualize a considerable SD drop at the posterobasal wall resembling perfusion defects, being attributed to beam harde...
Source: The International Journal of Cardiovascular Imaging - November 11, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

New X-ray imaging modalities and their integration with intravascular imaging and interventionsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  During recent years various techniques emerged providing more detailed images and insights in the cardiovascular system. C-Arm computed tomography is currently introduced in cardiac imaging offering the potential of three dimensional imaging of the coronary arteries, the cardiac chambers, venous system and a variety of anatomic anomalies inside the interventional environment. Furthermore it might enable perfusion imaging during percutaneous coronary intervention (PCI). Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are meanwhile established tools for detailed assessment of th...
Source: The International Journal of Cardiovascular Imaging - November 7, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Helical prospective ECG-gating in cardiac computed tomography: radiation dose and image qualityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Helical prospective ECG-gating (pECG) may reduce radiation dose while maintaining the advantages of helical image acquisition for coronary computed tomography angiography (CCTA). Aim of this study was to evaluate helical pECG–gating in CCTA in regards to radiation dose and image quality. 86 patients undergoing 64-multislice CCTA were enrolled. pECG-gating was performed in patients with regular heart rates (HR) < 65 bpm; with the gating window set at 70–85% of the cardiac cycle. All patients received oral and some received additional IV beta-blockers to achieve HR < ...
Source: The International Journal of Cardiovascular Imaging - November 6, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Close cardiac surveillance of patients treated with anthracyclines, also necessary after chemotherapy?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Editorial CommentDOI 10.1007/s10554-009-9525-3Authors Leo H. B. Baur, University of Maastricht Department of Cardiology, Atrium Medical Centre Parkstad Henri Dunantstreet 5 6401 CX Heerlen The Netherlands Journal The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)Online ISSN 1573-0743Print ISSN 1569-5794 (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - November 5, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Dual-source CT coronary angiography without heart rate or rhythm control in comparison with conventional coronary angiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To explore the value of dual-source CT angiography (DSCTA) in diagnosing coronary artery stenosis (CAS) without heart rate or rhythm control. Eighty-nine patients with different heart rates/rhythms underwent both DSCTA and conventional coronary angiography (CCA) in 1 week. The diagnostic quality of normal coronary arteries and stenosed segments using DSCTA and CCA were analyzed, respectively, with CCA as the gold standard. Kappa test was used to assess the intermodality agreement between DSCTA and CCA in grading CAS. The value of DSCTA in diagnosing CAS (>50% stenoses) were analyzed as well....
Source: The International Journal of Cardiovascular Imaging - November 4, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

New approaches for the assessment of vessel sizes in quantitative (cardio-)vascular X-ray analysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  This paper presents new approaches for the assessment of the arterial and reference diameters in (cardio-)vascular X-ray images, designed to overcome the problems experienced in conventional quantitative coronary and vascular angiography approaches. In single or “straight” vessel segments, the arterial and reference diameter directions were made independent of each other in order to be able to measure the minimal lumen diameter (MLD) more accurately, especially in curved vessel segments. For ostial segments, an extension of this approach was used, to allow measurement of ostial lesions in sidebr...
Source: The International Journal of Cardiovascular Imaging - November 4, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

3-D reconstruction of the coronary artery tree from multiple views of a rotational X-ray angiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To present an efficient and robust method for 3-D reconstruction of the coronary artery tree from multiple ECG-gated views of an X-ray angiography. 2-D coronary artery centerlines are extracted automatically from X-ray projection images using an enhanced multi-scale analysis. For the difficult data with low vessel contrast, a semi-automatic tool based on fast marching method is implemented to allow manual correction of automatically-extracted 2-D centerlines. First, we formulate the 3-D symbolic reconstruction of coronary arteries from multiple views as an energy minimization problem incorporating a...
Source: The International Journal of Cardiovascular Imaging - November 3, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Protective modulation of carotid atherosclerosis in hyperalphalipoproteinemic individualsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study was conducted on 169 asymptomatic individuals, classified as hyperalphalipoproteinemic (Hyper-A) (Hyper-A, n = 71, HDL-C ≥68 mg/dL) and controls (CTL) (CTL, n = 98, HDL-C >32 and <68 mg/dL). Enzymatic, nephelometric and ultracentrifugation methods were used for biochemical determinations. Hepatic lipase (HL), lipoprotein lipase (LPL), cholesteryl ester transfer protein (CETP) and phospholipids transfer protein (PLTP) activities were measured by radiometric exogenous methods. The prevalence of dyslipidemia, hypertension, smoking, sedentariness, postmenopausal women, coron...
Source: The International Journal of Cardiovascular Imaging - October 30, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

A black mobile mass: diagnosis and managementemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present the case of a 37 year old man who came into the Emergency department complaining of pleuritic chest pain. ECG revealed an evolving anterior wall infarction and transthoracic echocardiogram showed a big mobile thrombus in the ventricular apex. In order to confirm diagnosis and to differentiate other entities like pseudoaneurysm, contrast echocardiography and cardiac MRI with late gadolinium enhancement were performed and allowed a definitive diagnosis. Our patient was treated with intravenous heparin and then with oral anticoagulation. Two months later, echocardiogram showed an apical non-mobile an...
Source: The International Journal of Cardiovascular Imaging - October 29, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Cardiovascular magnetic resonance T2 signal abnormalities in left ventricular ballooning syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, we describe elevated T2 signal consistent with myocardial edema in patients with LVBS. The T2 signal is highest in myocardium with the most impaired function and resolves over time. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10554-009-9515-5Authors Subodh B. Joshi, Washington Hospital Center Section of Cardiology, Department of Medicine Washington DC USATania Chao, Washington Hospital Center Section of Cardiology, Department of Medicine Washington DC USADaniel A. Herzka, Philips Research North America Clinical Sites Research Program Bethesda MD USAPeter R. Zeman, Washington Hospita...
Source: The International Journal of Cardiovascular Imaging - October 28, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Relation of plaque size to compositions as determined by an in vivo volumetric intravascular ultrasound radiofrequency analysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  As the plaques have enlarged, the changes in specific plaque compositions have not been sufficiently investigated. We evaluated the relation of plaque size to each plaque component (fibrotic, fibrofatty, dense calcium, and necrotic core) in 244 patients with volumetric virtual histology intravascular ultrasound analysis. Plaque volume was significantly correlated with fibrotic volume (r = 0.886, P < 0.001), necrotic core volume (r = 0.716, P < 0.001), fibrofatty volume (r = 0.572, P < 0.001), and dense calcium volume (r = ...
Source: The International Journal of Cardiovascular Imaging - October 23, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Predictors of ventricular arrhythmias in patients with mitral valve prolapseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Arrhythmias have been reported to occur frequently in symptomatic patients with mitral valve prolapse (MVP). The mechanisms causing ventricular arrhythmias in patients with MVP have not been fully investigated. The purpose of this study was to determine the clinical, echocardiographic and heart rate variability parameters, and plasma concentrations of electrolytes and inflammatory markers in predicting ventricular arrhythmias in patients with MVP. A total of 58 consecutive patients with MVP were included in this study. We performed electrocardiography, echocardiography, holter analysis, routine bioc...
Source: The International Journal of Cardiovascular Imaging - October 22, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Mitral annulus staining during left ventriculographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Case in PointDOI 10.1007/s10554-009-9519-1Authors Pilar Egea-Serrano, Puerta del Mar University Hospital Hemodynamic and Interventionist Cardiology Unit, Department of Cardiology Avda. Ana de Viya, 21 11009 Cádiz SpainRoque Arana, Puerta del Mar University Hospital Hemodynamic and Interventionist Cardiology Unit, Department of Cardiology Avda. Ana de Viya, 21 11009 Cádiz SpainManuel Sancho, Puerta del Mar University Hospital Hemodynamic and Interventionist Cardiology Unit, Department of Cardiology Avda. Ana de Viya, 21 11009 Cádiz Spain Journal The International Journal of...
Source: The International Journal of Cardiovascular Imaging - October 20, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Relation of ventricular-vascular coupling to exercise capacity in ischemic cardiomyopathy: a cardiac multi-modality imaging studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The purpose of this study was to examine the relationship between noninvasive measurements of ventricular-vascular coupling (VVC) with exercise tolerance, and compared the value of VVC versus other traditional determinants of exercise capacity in this population. 43 patients with ischemic CMP (age 59 ± 9 years, mean EF 24 ± 8%) underwent cardiopulmonary exercise testing, echocardiography and cardiac magnetic resonance (CMR). VVC was defined non-invasively by the ratio of ventricular systolic elastance (Ees) to the arterial elastance (Ea), where Ees = end-systolic...
Source: The International Journal of Cardiovascular Imaging - October 13, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Systolic versus diastolic cardiac function variables during epirubicin treatment for breast canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Anthracyclines are important in the treatment of numerous malignant diseases but the use is limited by a risk of heart failure (CHF). LVEF (left ventricular ejection fraction) measurements by radio-nuclide ventriculography with multiple gated acquisition (MUGA) is often used for cardiac monitoring. However, diastolic variables have been proposed as sensitive supplements. It was hypothesized that a change in diastolic filling variables measured by MUGA could identify individuals after epirubicin treatment (ET) in risk of developing heart failure. A retrospective analysis of registered raw data. Indiv...
Source: The International Journal of Cardiovascular Imaging - October 13, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

CT angiography versus invasive angiography for the diagnosis of total occlusionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Computed Tomography Coronary Angiography (CTCA) for the diagnosis and evaluation of coronary artery occlusive disease has rapidly gained acceptance among clinicians. Its growing use in selected populations has provided a wealth of data, leading to a recent flurry of articles describing both the benefits and limitations of this imaging modality. In this article, we describe the case of an 80 year old woman who presented with anginal symptoms, who first underwent CTCA which suggested severe right coronary artery stenosis. A subsequent invasive coronary angiogram was crucial in revealing a total o...
Source: The International Journal of Cardiovascular Imaging - October 11, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Effects of distal protection on left ventricular function in acute anterior myocardial infarction: a Doppler echocardiographic studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Whether distal protection devices (DPDs) during percutaneous coronary intervention (PCI) can improve myocardial function in patients with acute myocardial infarction (AMI) is still under debate. Using tissue Doppler imaging (TDI), we evaluate the global and regional left ventricular systolic and diastolic functions in patients with anterior AMI using DPDs compared with conventional PCI. Ninety-six patients with anterior AMI were randomly assigned to either PCI with DPDs (DPD, n = 46) or traditional PCI (control, n = 50) groups. At the 3- and 6-month follow-ups, the DPD group had a...
Source: The International Journal of Cardiovascular Imaging - October 4, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Assessment of obstruction length and optimal viewing angle from biplane X-ray angiogramsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, the new 3D QCA approach allows highly accurate and precise assessments of obstruction length and optimal viewing angle from X-ray angiography. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10554-009-9509-3Authors Shengxian Tu, Leiden University Medical Center Department of Radiology Leiden The NetherlandsGerhard Koning, Leiden University Medical Center Department of Radiology Leiden The NetherlandsWouter Jukema, Leiden University Medical Center Department of Cardiology Leiden The NetherlandsJohan H. C. Reiber, Leiden University Medical Center Department of Radiology Leiden The Netherl...
Source: The International Journal of Cardiovascular Imaging - September 29, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

FDG–PET can distinguish inflamed from non-inflamed plaque in an animal model of atherosclerosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study confirms that in an animal model of inflamed and non-inflamed atherosclerosis, significant differences in FDG SUV allow differentiation of highly inflamed atherosclerotic aortas from those stabilized by statin therapy and low cholesterol diet and controls. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10554-009-9506-6Authors John R. Davies, University of Cambridge, Addenbrooke’s Hospital Division of Cardiovascular Medicine Cambridge UKDavid Izquierdo-Garcia, University of Cambridge, Addenbrooke’s Hospital Wolfson Brain Imaging Centre Box 65 Cambridge CB2 0QQ UKJames H. F. Rudd, Unive...
Source: The International Journal of Cardiovascular Imaging - September 29, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Reproducibility and accuracy of automated measurement for dynamic arterial lumen area by cardiovascular magnetic resonanceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Bright blood cine images acquired using Magnetic Resonance Imaging contain simple contrast that is tractable to automated analysis, which can be used to derive a measure of arterial compliance that is known to correlate with disease severity. The purpose of this work was to evaluate whether automated methods could be used reliably on a clinically relevant population, and to assess the precision of these measurements so that it could be compared with expert manual assessment. In this paper we apply an algorithm similar to that used by Krug et al., and the exact processing steps are described in detai...
Source: The International Journal of Cardiovascular Imaging - September 25, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Stent implant follow-up in intravascular optical coherence tomography imagesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objectives of this article are (i) to utilize computer methods in detection of stent struts imaged in vivo by optical coherence tomography (OCT) during percutaneous coronary interventions (PCI); (ii) to provide measurements for the assessment and monitoring of in-stent restenosis by OCT post PCI. Thirty-nine OCT cross-sections from seven pullbacks from seven patients presenting varying degrees of neointimal hyperplasia (NIH) are selected, and stent struts are detected. Stent and lumen boundaries are reconstructed and one experienced observer analyzed the strut detection, the lumen and stent area measurements, as we...
Source: The International Journal of Cardiovascular Imaging - September 24, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Obstruction and sequestration: a case of apical hypertrophic cardiomyopathy concomitant with subaortic obstruction, apical sequestration, and valvular aortic stenosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We presented an unique case of apical hypertrophic cardiomyopathy concomitant with subaortic obstruction, apical sequestration, and valvular aortic stenosis. The echocardiographic findings were conflicting and characterized by quadruple pressure gradients within the left ventricle, which were compatible with the findings of 64-slice computed tomography imaging and cardiac catheterization. Content Type Journal ArticleCategory Case in PointDOI 10.1007/s10554-009-9494-6Authors Chao-Chin Chen, Lo-Tung Poh-Ai Hospital Division of Cardiology, Department of Medicine 83 Nan Chang St. Lotung I-Lan 265 TaiwanMeng-Huan Lei, Lo...
Source: The International Journal of Cardiovascular Imaging - September 24, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Imaging features of intramural hematoma of the aortaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Intramural Hematoma (IMH) is defined as localized hemorrhage within the aortic wall and is included in the acute aortic syndrome spectrum with aortic dissection and penetrating aortic ulcer. The mortality from IMH is similar to classic aortic dissection (21%). 16% of patients with IMH will evolve to classic aortic dissection over time. Despite this confusion exists regarding the precise definitions and radiologic features of IMH versus penetrating ulcers with mural thrombus and overt aortic dissection. Content Type Journal ArticleCategory ReviewDOI 10.1007/s10554-009-9504-8Authors Orla Buckley, ...
Source: The International Journal of Cardiovascular Imaging - September 24, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Quantitative image analysis for the detection of motion artefacts in coronary artery computed tomographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, the quantitative analysis together with the qualitative analysis rules out artefact-induced stenosis. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10554-009-9502-xAuthors Wisnumurti Kristanto, University Medical Center Groningen, University of Groningen Department of Radiology Groningen The NetherlandsPeter M. van Ooijen, University Medical Center Groningen, University of Groningen Department of Radiology Groningen The NetherlandsRiksta Dikkers, University Medical Center Groningen, University of Groningen Department of Radiology Groningen The NetherlandsMarcel J. Greuter, University ...
Source: The International Journal of Cardiovascular Imaging - September 24, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Constriction infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a 48-year-old male admitted with atrial flutter, acute chest infection and signs of right heart congestion. PC was documented one year previously on a non-contrast CT chest. On this occasion, cardiac catheterisation confirmed hemodynamically significant CCP and cardiac magnetic resonance (cMR) study showed contiguous mass lesions in the pericardium, compression of the right ventricle, enlargement of the right atrium, hepatic enlargement and a pneumonic process in the left lung. He was commenced on antibiotics and anti-tuberculous therapy with a diagnosis of bacterial super-infection of tuberculous CCP. This...
Source: The International Journal of Cardiovascular Imaging - September 23, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

123I-BMIPP and 99mTc-TF discordance on myocardial scintigraphy and it’s correlation with functional recovery following acute myocardial infarction: role of conventional echocardiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract   123I-β-methyl-iodophenyl pentadecanoic acid (BMIPP) and 99mTc-Tetrofosmin (TF) mismatch designated as stunned myocardium having both systolic and diastolic components. The degree of mismatch might reflect subsequent functional improvement, and this study was designed to unravel the impact of mismatched defect score (MMDS) on recovery of both systolic and diastolic function following acute myocardial infarction (AMI). Forty patients with recent AMI were recruited, and all of them underwent emergency percutaneous coronary intervention. Echocardiography and BMIPP and TF cardiac scintigraphy were per...
Source: The International Journal of Cardiovascular Imaging - September 19, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Coronary calcium mass scores measured by identical 64-slice MDCT scanners are comparable: a cardiac phantom studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To assess whether absolute mass scores are comparable or differ between identical 64-slice MDCT scanners of the same manufacturer and to compare absolute mass scores to the physical mass and between scan modes using a calcified phantom. A non-moving anthropomorphic phantom with nine calcifications of three sizes and three densities was scanned 30 times on three 64-slice MDCT scanners of manufacturer A and on three 64-slice MDCT scanners of manufacturer B in both sequential and spiral scan mode. The mean mass scores and mass score variabilities of seven calcifications were determined for all scanners...
Source: The International Journal of Cardiovascular Imaging - September 19, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Accessory left atrial diverticulae: contractile properties depicted with 64-slice cine-cardiac CTemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To assess the contractility of accessory left atrial appendages (LAAs) using multiphasic cardiac CT. We retrospectively analyzed the presence, location, size and contractile properties of accessory LAAs using multiphasic cardiac 64-slice CT in 102 consecutive patients (63 males, 39 females, mean age 57). Multiplanar reformats were used to create image planes in axial oblique, sagittal oblique and coronal oblique planes. For all appendages with an orifice diameter ≥ 10 mm, axial and sagittal diameters and appendage volumes were recorded in atrial diastole and systole. Regression anal...
Source: The International Journal of Cardiovascular Imaging - September 18, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

HIV infection and abnormal regional ventricular functionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To examine the effect of HIV infection on regional left ventricular dysfunction in cardiovascularly asymptomatic individuals. Nineteen HIV-negative and 27 HIV-positive cardiovascularly asymptomatic study participants in Baltimore, Maryland were selected and underwent tagged cardiac magnetic resonance imaging. Regional left ventricular myocardial mid-wall peak systolic circumferential strain (Ecc) and early diastolic strain rate (SRE) of the left ventricle were assessed with the use of the harmonic phase analysis. The average Ecc and SRE measurements were compared between HIV-negative and HIV-positiv...
Source: The International Journal of Cardiovascular Imaging - September 17, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Tc-99m sestamibi single photon emission computed tomography for guiding percutaneous coronary intervention in patients with multivessel disease: a comparison with quantitative coronary angiography and fractional flow reserveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To evaluate the accuracy of myocardial perfusion SPECT (MPI) in the detection and allocation of vessel specific perfusion defects (PD) using standard distribution territories in a routine clinical procedure of patients with multivessel disease (MVD). Combined quantitative coronary angiography and fractional flow reserve (QCA/FFR) measurements were used as invasive reference standard. 216 vessels in 72 MVD patients (67 ± 10 years, 28 female) were investigated using MPI and QCA. FFR of 93 vessels with intermediate stenoses was determined. MPI detected significant stenoses according to ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Spectroscopy to improve identification of vulnerable plaques in cardiovascular diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Many apparent healthy persons die from cardiovascular disease, despite major advances in prevention and treatment of cardiovascular disease. Traditional cardiovascular risk factors are able to predict cardiovascular events in the long run, but fail to assess current disease activity or nearby cardiovascular events. There is a clear relation between the occurrence of cardiovascular events and the presence of so-called vulnerable plaques. These vulnerable plaques are characterized by active inflammation, a thin cap and a large lipid pool. Spectroscopy is an optical imaging technique which depicts the ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Limited value of digital subtraction angiography in the evaluation of cell-based therapy in patients with limb ischemiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Cell-based therapy has been proposed as a novel strategy for patients with severe peripheral arterial disease by stimulating vascular growth. In clinical studies of this therapy, the emphasis has been on demonstrating recovery of clinical parameters, rather than on evaluation of blood flow recovery. Angiography is still the gold standard for the assessment of lower leg arteries. Therefore, we studied the usefulness of angiography in the evaluation of cell-based therapy. Sixteen patients with critical leg ischemia (ischemic rest pain or ulcers), or persistent (>12 months) profound disabling c...
Source: The International Journal of Cardiovascular Imaging - September 16, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Intra-observer and interobserver variability of biventricular function, volumes and mass in patients with congenital heart disease measured by CMR imagingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Cardiovascular magnetic resonance (CMR) imaging provides highly accurate measurements of biventricular volumes and mass and is frequently used in the follow-up of patients with acquired and congenital heart disease (CHD). Data on reproducibility are limited in patients with CHD, while measurements should be reproducible, since CMR imaging has a main contribution to decision making and timing of (re)interventions. The aim of this study was to assess intra-observer and interobserver variability of biventricular function, volumes and mass in a heterogeneous group of patients with CHD using CMR imaging....
Source: The International Journal of Cardiovascular Imaging - September 16, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Intramyocardial hemorrhage and microvascular obstruction after primary percutaneous coronary interventionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Reperfusion may cause intramyocardial hemorrhage (IMH) by extravasation of erythrocytes through severely damaged endothelial walls. The purpose of the study was to evaluate the clinical significance of IMH in relation to infarct size, microvascular obstruction (MVO) and function in patients after primary percutaneous intervention. Forty-five patients underwent cardiovascular MR imaging (CMR) 1 week and 4 months after primary stenting for a first acute myocardial infarction. T2-weighted spin-echo imaging (T2W) was used to assess infarct related edema and IMH, and delayed enhancement (DE) wa...
Source: The International Journal of Cardiovascular Imaging - September 16, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Evaluation of vascular reactivity of young male hypogonadotrophic hypogonadism patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  We aimed to study the vascular reactivity of young male hypogonadal hypogonadism patients without any cardiovascular risk factors and compare these findings with the ones of age-matched healthy controls. Study population consisted of 26 young male hypogonadotrophic hypogonadism patients (20.9 ± 1.3 years) and 25 age-matched healthy male controls (21.8 ± 2.9 years, P = NS). In addition to detailed hormonal analysis, each subject underwent ultrasound study of right brachial artery. Vessel diameter was measured at rest, during reactive hyperemia [endothelium-dep...
Source: The International Journal of Cardiovascular Imaging - September 16, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Determination of right ventricular end systole by cardiovascular magnetic resonance imaging: a standard method of selectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  For reproducible measurements of right ventricular (RV) volume and function, it may be important to use a consistent method to identify end systole (ES). We determined whether a significant difference exists between RV volumes measured using varying criteria from previous studies to define the timing of ES. In three normal subjects and nine patients with congenital heart disease, we measured RV volume from 3D reconstructions generated from 12 short and long axis magnetic resonance images (MRI). Cine frames analyzed included two frames before and three frames following ES, which we determined as the ...
Source: The International Journal of Cardiovascular Imaging - September 16, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

31P cardiac magnetic resonance spectroscopy during leg exercise at 3 Teslaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Investigation of phosphorus (31P) magnetic resonance spectroscopy under stress conditions provides a non-invasive tool to examine alterations in cardiac high-energy phosphate metabolism that may not be evident at rest. Our aim was to establish cardiac 31P MR spectroscopy during leg exercise at 3T. The increased field strength should provide a higher signal to noise ratio than at lower field strengths. Furthermore, relatively high temporal resolution at a sufficiently fine spatial resolution should be feasible. 31P MR spectra were obtained with a 3D acquisition weighted chemical shift imaging sequence...
Source: The International Journal of Cardiovascular Imaging - August 21, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

An appearance of “non-compaction” of the right systemic ventricle is common in congenitally corrected transposition of the great arteriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s10554-009-9488-4Authors John Purvis, Altnagelvin Hospital, Western HSC Trust Department of Cardiology Glenshane Road Londonderry BT47 6SB UKStephen Barr, Altnagelvin Hospital, Western HSC Trust Department of Cardiology Glenshane Road Londonderry BT47 6SB UK Journal The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)Online ISSN 1573-0743Print ISSN 1569-5794 (Source: The International Journal of Cardiovascular Imaging)
Source: The International Journal of Cardiovascular Imaging - August 12, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Effect of iron overload on exercise capacity in thalassemic patients with heart failureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  In b-thalassemia, myocardial iron overload contributes to heart failure, despite chelation treatment. We hypothesized that myocardial T2*, an index of iron overload, influences patients’ physical activity. We assessed a thalassemic population by both cardiovascular magnetic resonance imaging (CMR) and ergospirometry test. Sixty-six thalassemic patients aged 27 (19–40) years, 30 without (NHF) and 36 with heart failure (HF), were studied. Cardiac T2* and left ventricular ejection fraction (LVEF) were evaluated using a 1.5 T system. VO2max, AT, Mets and duration of exercise by ergospirome...
Source: The International Journal of Cardiovascular Imaging - August 12, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Equilibrium radionuclide angiography for evaluating the effect of percutaneous coronary intervention on ventricular aneurysm formation and systolic synchrony in patients with acute myocardial infarctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Left ventricular aneurysm (LVA) after myocardial infarction often results in serious complications. So far, when the LVA happened is unclear. Furthermore, it is a question whether percutaneous coronary intervention (PCI) can change or reverse the formation of LVA? And the report about the long term follow-up was rare. So this study was to evaluate the time sequence of the formation of LVA through left ventriculography in large scale of consecutive acute myocardial infarction (AMI) patients and evaluate the influence of PCI at different time after AMI on the change of systolic synchrony through phase...
Source: The International Journal of Cardiovascular Imaging - August 12, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Optimal image reconstruction phase at low and high heart rates in dual-source CT coronary angiographyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The purpose of this study was to determine the cardiac phase having the highest coronary sharpness for low and high heart rate patients scanned with dual source CT (DSCT) and to compare coronary image sharpness over different cardiac phases. DSCT coronary CT scans for 30 low heart rate (≤70 beats per minute- bpm) and 30 high heart rate (>70 bpm) patients were reconstructed into different cardiac phases, starting at 30% and increasing at 5% increments until 70%. A blinded observer graded image sharpness per coronary segment, from which sharpness scores were produced for the right (RCA)...
Source: The International Journal of Cardiovascular Imaging - August 9, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

High resolution magnetic resonance imaging in atherosclerotic mice treated with ezetimibeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  High field magnetic resonance imaging (MRI) was performed to investigate the long-term effect of ezetimibe (eze), a cholesterol resorption blocker, on atherosclerotic lesion formation in the thoracic aorta of apolipoprotein E-deficient mice (apoE −/− ) in comparison to wild type mice (WT). Fifteen-month-old apoE −/− (Western type diet), apoE −/−eze (Western type diet with eze) which received eze (5 mc/kg/day) continuously, and age-matched WT (normal chow) were studied using contrast-enhanced 3D turbo-spin-echo sequences (RARE factor 2) on a 7 Tesla scanner. Vessel parameters we...
Source: The International Journal of Cardiovascular Imaging - August 7, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Prevalence of noncardiac findings on low dose 64-slice computed tomography used for attenuation correction in myocardial perfusion imaging with SPECTemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Electrocardiogram (ECG)-triggered, low dose computed tomography (CT) is increasingly used for attenuation correction in myocardial perfusion imaging (MPI) with SPECT. The purpose of the study was to assess the prevalence of relevant noncardiac findings in the field-of-view of such attenuation correction CT scans. Five hundred and eighty-two consecutive patients (211 female, 371 male; mean age: 64 ± 11 years; BMI: 27.7 ± 5.3 kg/m2) underwent 64-slice, ECG-triggered CT scanning for attenuation correction of MPI with SPECT. Relevant findings were defined as abnormalities...
Source: The International Journal of Cardiovascular Imaging - August 7, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

New aspects on the assessment of left ventricular dyssynchrony by tissue Doppler echocardiography: comparison of myocardial velocity vs. displacement curvesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The purpose of this study is to assess the incremental value of tissue Doppler (TDI) derived displacement curves (TDint) compared to TDI velocity curves (TDvel) for the evaluation of left ventricular (LV) dyssynchrony (LVD). About 25 patients (pts.) with systolic heart failure were studied by TDvel and TDint. Four TDI sample volumes were placed at the basal and four at the mid ventricular myocardium, utilising two imaging planes. LV dyssynchrony (LVD) was defined as an interregional delay of >40 ms corrected for heart rate. 10 pts. had synchronous contraction, 15 pts. LVD as defined by two e...
Source: The International Journal of Cardiovascular Imaging - August 4, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Is there a role for CT coronary angiography in patients with symptomatic angina? Effect of coronary calcium score on identification of stenosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We examined the relation between coronary calcium score (CS) and the performance of CTCA in patients with stable and unstable angina in order to understand under which conditions CTCA might be a gate-keeper to conventional coronary angiography (CCA) in such patients. We included 360 patients between 50 and 70 years old with stable and unstable angina who were clinically referred for CCA irrespective of CS. Patients received CS and CCTA on 64-slice scanners in a multicenter cross-sectional trial. The institutional review board approved the study. Diagnostic performance of CTCA to detect or rule out significant cor...
Source: The International Journal of Cardiovascular Imaging - August 2, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallotemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The aim of this study was to evaluate the feasibility of right ventricular (RV) longitudinal peak systolic strain (LPSS) assessment for the follow-up of adult patients with corrected tetralogy of Fallot (TOF). Adult patients (n = 18) with corrected TOF underwent echocardiography and CMR twice with a time interval of 4.2 ± 1.7 years. RV performance was derived from CMR, and included RV volumes and ejection fraction (EF). LPSS was calculated globally (GLPSS) and in the RV free wall (LPSS FW), with echocardiographic speckle-tracking strain-analysis. Baseline (G)LPSS values were...
Source: The International Journal of Cardiovascular Imaging - July 30, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals