Metabolic syndrome and psoriatic arthritis among patients with psoriasis vulgaris: Quality of life and prevalence
This study aimed to evaluate the prevalence of metabolic syndrome (MetS) and psoriatic arthritis (PsA) and to investigate HRQoL and the prevalence of hypertension, type 2 diabetes mellitus (T2DM), obesity and dyslipidemia. In a cross‐sectional design, patients d iagnosed with plaque psoriasis answered an interview and standardized questionnaires (Dermatology Life Quality Index questionnaire [DLQI], 36‐Item Short Form Health Survey [SF‐36] and EuroQol Five‐Dimension Questionnaire Three‐Level version [EQ‐5D‐3L]). Physical examination and several t ests to assess desired outcomes were performed by a dermatologis...
Source: The Journal of Dermatology - November 26, 2018 Category: Dermatology Authors: Cacilda S. Souza,
Caio C. S. Castro,
Francisca R. O. Carneiro,
Jane M. N. Pinto,
Lincoln H. Z. Fabricio,
Luna Azulay ‐Abulafia,
Ricardo Romiti,
Tania F. Cestari,
Cláudia E. Suzuki,
Priscila M. Biegun,
Luciana S. Guedes,
Luiza K. M. Oyafuso Tags: Original Article Source Type: research
Dramatic effect of nivolumab against melanoma and immune ‐related liver toxicity: A detailed histopathological and immunohistochemical analysis of nivolumab‐induced liver toxicity
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 26, 2018 Category: Dermatology Authors: Takeshi Namiki,
Kohei Nojima,
Sakiko Chikazawa,
Yutaro Iwamoto,
Yuki Otsuki,
Hind Albusani,
Keiko Miura,
Yusuke Kiyokawa,
Takahiro Asakage,
Hiroo Yokozeki Tags: Letter to the Editor Source Type: research
Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation
AbstractGeneralized pustular psoriasis (GPP) is a systemic inflammatory disease that presents with erythema and sterile pustules, pathologically characterized by Kogoj's spongiform pustules. GPP is sometimes accompanied by mucosal involvement, and the most common lesion is on the tongue.IL36RN mutation was found to contribute to the pathogenesis of GPP especially in patients who develop GPP without a past medical history of psoriasis vulgaris. The association ofIL36RN mutation with mucosal involvement in GPP is controversial. We herein report a 60 ‐year‐old male GPP patient with no past history of plaque psoriasis pres...
Source: The Journal of Dermatology - November 26, 2018 Category: Dermatology Authors: Shiori Komatsuda,
Masahiro Kamata,
Chika Chijiwa,
Kaoru Namiki,
Saki Fukaya,
Kotaro Hayashi,
Atsuko Fukuyasu,
Takamitsu Tanaka,
Takeko Ishikawa,
Takamitsu Ohnishi,
Koichiro Abe,
Takatsugu Yamamoto,
Naohiko Aozasa,
Kazumitsu Sugiura,
Yayoi Ta Tags: Concise Communication Source Type: research
Lichen sclerosus et atrophicus diagnosed in a child accompanied with local periodontal attachment loss and maxillary deficiency: A rare case report
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 23, 2018 Category: Dermatology Authors: Wenxia Meng,
Yinshen Yang,
Shuguang Liu,
Wei Guo,
Hui Xiao,
Hongmei Zhou Tags: Letter to the Editor Source Type: research
Disseminated dermatophytosis due to Nannizzia gypsea (Microsporum gypseum) in an elderly patient
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 23, 2018 Category: Dermatology Authors: Toshio Demitsu,
Tomoko Yamada,
Naoka Umemoto,
Maki Kakurai,
Tatsuo Maeda,
Kazutoshi Harada,
Masaaki Kawase Tags: Letter to the Editor Source Type: research
Risk of psychiatric disorders in rosacea: A nationwide, population ‐based, cohort study in Taiwan
In conclusion, rosacea is related to various psychiatric disorders. In addition to anxiety and depression, patients are also at increased risk of phobic disorder and obsessive –compulsive disorder. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 22, 2018 Category: Dermatology Authors: Chih ‐Tsung Hung,
Chien‐Ping Chiang,
Chi‐Hsiang Chung,
Chang‐Huei Tsao,
Wu‐Chien Chien,
Wei‐Ming Wang Tags: Original Article Source Type: research
Early ambulation versus bedrest after skin grafting in extramammary Paget's disease
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 19, 2018 Category: Dermatology Authors: Tae Hwan Park Tags: Letter to the Editor Source Type: research
Papuloerythroderma ‐like cutaneous involvement of a CD62L− subclone of T‐cell prolymphocytic leukemia
We report the case of an 88 ‐year‐old Japanese man with erythrodermic involvement of T‐cell prolymphocytic leukemia (T‐PLL). He had a history of pharyngeal diffuse large B‐cell lymphoma successfully treated with polychemotherapy including cyclophosphamide and epirubicin, 6 years before the current illness. He present ed with numerous reddish, coalescing, flat‐topped papules on the trunk and extremities, sparing the skin folds of the abdomen, the features of which mimicked those of papuloerythroderma. Immunohistochemistry showed perivascular and epidermotropic infiltration of CD3+ CD4+ T cells in the cutaneous l...
Source: The Journal of Dermatology - November 19, 2018 Category: Dermatology Authors: Yuki Nakagawa,
Toshihisa Hamada,
Mayuko Matsuda,
Taisuke Kanno,
Takumi Kondo,
Takahide Takahashi,
Toshiyuki Watanabe,
Ken Okada,
Toru Kawakami,
Tomoko Miyake,
Shin Morizane,
Keiji Iwatsuki Tags: Concise Communication Source Type: research
Demographic and clinical characteristics of spinal calcinosis in systemic sclerosis: Possible association with peripheral angiopathy
The objective was to evaluate the demographic and clinical characteristics of systemic sclerosis (SSc) patients with spinal calcinosis. Paraspinal and intraspinal calcinosis was assessed blindly by orthopedic surgeons specializing in spinal diseases using chest high ‐resolution computed tomography (CT) that was performed for the screening and prospecting of interstitial lung disease in 159 Japanese SSc patients. Among these patients, we identified 27 (17%) with spinal calcinosis, and the most common site was cervical level at 77.8% (21/27). The frequency of s pinal calcinosis in the late stage was higher than in the earl...
Source: The Journal of Dermatology - November 16, 2018 Category: Dermatology Authors: Sei ‐ichiro Motegi,
Akiko Sekiguchi,
Yukio Yonemoto,
Tokue Mieda,
Hirotaka Chikuda,
Osamu Ishikawa Tags: Original Article Source Type: research
Reply to “Early ambulation versus bedrest after skin grafting in extramammary Paget's disease”
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 16, 2018 Category: Dermatology Authors: Takuya Maeda,
Koji Yoshino,
Kojiro Nagai,
Satoe Oaku,
Megumi Kato,
Azusa Hiura,
Hiroo Hata Tags: Letter to the Editor Source Type: research
Case of generalized anhidrosis associated with diffuse reticular hyperpigmentation and syndactyly
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 16, 2018 Category: Dermatology Authors: Takeshi Namiki,
Takashi Hashimoto,
Chika Omigawa,
Tomoko Fujimoto,
Tsukasa Ugajin,
Keiko Miura,
Takahiro Satoh,
Hajime Nakano,
Hiroo Yokozeki Tags: Letter to the Editor Source Type: research
Cancer risk in 892 089 patients with psoriasis in Korea: A nationwide population‐based cohort study
AbstractThe relationship between psoriasis and cancer has not yet been established. The aim of this study was to evaluate the association of psoriasis with certain cancers using national statistics. All patients with psoriasis (n = 892 089; 51.7% male) and age‐ and sex‐matched control subjects (n = 4 460 445) at a 5:1 ratio were enrolled using data from the National Health Insurance Service between 2007 and 2014 in Korea. In psoriatic subjects, overall cancer risk was higher than for subjects without psoriasis after adjusting for income level, diabetes, hypertension, dyslipidemia and pl ace of residence (hazard ...
Source: The Journal of Dermatology - November 16, 2018 Category: Dermatology Authors: Ji Hyun Lee,
Hyo Jung Kim,
Kyung Do Han,
Ha ‐Na Kim,
Young Min Park,
Jun Young Lee,
Yong‐Gyu Park,
Young Bok Lee Tags: Original Article Source Type: research
Aggravation of vitiligo by an electric heating pad: A possible case of heat ‐triggered Koebnerization in vitiligo
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 16, 2018 Category: Dermatology Authors: Jae Won Lee,
Shinwon Hwang,
Min ‐Young Park,
Sang Ho Oh Tags: Letter to the Editor Source Type: research
Expression of T ‐cell immunoglobulin and immunoreceptor tyrosine‐based inhibitory motif domain on CD4+ T cells in patients with atopic dermatitis
In this study, we examined the expression levels of TIGIT and their association with clinical features in patients with AD. TIGIT expression on CD4+ T cells, central memory T cells, effector memory T cells and regulatory T cells was determined by flow cytometry. CD4+ T cells exhibited enhanced TIGIT expression in patients with AD compared with healthy individuals. In particular, effector memory T cells and regulatory T cells, but not central memory T cells, exhibited higher TIGIT expression in patients with AD than in healthy individuals. The frequency of TIGIT+ cells among CD4+ T cells was significantly increased in patie...
Source: The Journal of Dermatology - November 7, 2018 Category: Dermatology Authors: Miki Kurita,
Yuki Yoshihara,
Yozo Ishiuji,
Mami Chihara,
Takaoki Ishiji,
Akihiko Asahina,
Koichi Yanaba Tags: Original Article Source Type: research
Improvement of nail lesions in a patient with psoriatic arthritis by switching the treatment from an anti ‐interleukin‐17A antibody to an anti‐tumor necrosis factor‐α antibody
The Journal of Dermatology, EarlyView. (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - November 7, 2018 Category: Dermatology Authors: Takayoshi Komatsu ‐Fujii,
Tetsuya Honda,
Atsushi Otsuka,
Kenji Kabashima Tags: Letter to the Editor Source Type: research
