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(Source: The Journal of Pain)
Source: The Journal of Pain - October 29, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - October 29, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - October 29, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

Role of NFκB in an Animal Model of Complex Regional Pain Syndrome–type I (CRPS-I)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: NFκB is involved in several pathogenic mechanisms that are believed to underlie the complex regional pain syndrome (CRPS), including ischemia, inflammation and sensitization. Chronic postischemia pain (CPIP) has been developed as an animal model that mimics the symptoms of CRPS-I. The possible involvement of NFκB in CRPS-I was studied using CPIP rats. Under sodium pentobarbital anesthesia, a tourniquet was placed around the rat left ankle joint, producing 3 hours of ischemia, followed by rapid reperfusion (IR injury). NFκB was measured in nuclear extracts of muscle and spinal cord tissue using ELISA. Moreover,...
Source: The Journal of Pain - October 29, 2009 Category: Materials Science Authors: Marissa de Mos, André Laferrière, Magali Millecamps, Mercedes Pilkington, Miriam C.J.M. Sturkenboom, Frank J.P.M. Huygen, Terence J. Coderre Tags: Original Reports Source Type: journals

How Neuroimaging Studies Have Challenged Us to Rethink: Is Chronic Pain a Disease?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: In this review, we present data from functional, structural, and molecular imaging studies in patients and animals supporting the notion that it might be time to reconsider chronic pain as a disease. Across a range of chronic pain conditions, similar observations have been made regarding changes in structure and function within the brains of patients. We discuss these observations within the framework of the current definition of a disease.Perspective: Neuroimaging studies have made a significant scientific impact in the study of pain. Knowledge of nociceptive processing in the noninjured and injured central nerv...
Source: The Journal of Pain - October 29, 2009 Category: Materials Science Authors: Irene Tracey, M. Catherine Bushnell Tags: Critical Review Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

Associations Between Race and Ethnicity and Treatment for Chronic Pain in the VAemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: The purpose of this study was to identify racial and ethnic differences in patient-reported rates of treatment for chronic pain and ratings of pain-treatment effectiveness among veterans treated in Veterans Affairs (VA) facilities. This was a cross-sectional analysis of data from 255,522 veterans who participated in the VA Survey of the Healthcare Experiences of Patients (SHEP) in Fiscal Year 2005. Measures included demographics, the Veterans Rand Health Survey-12, a single item inquiring if the patient received treatment for chronic pain in the VA within the prior 12 months, and a single item asking the patient ...
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Authors: Steven K. Dobscha, Geoffrey D. Soleck, Kathryn C. Dickinson, Diana J. Burgess, Michael R. Lasarev, Eun Sul Lee, Bentson H. McFarland Tags: Original Reports Source Type: journals

An Investigation Into the Effects of Frequency-Modulated Transcutaneous Electrical Nerve Stimulation (TENS) on Experimentally-Induced Pressure Pain in Healthy Human Participantsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study compared the effects of constant-frequency TENS and frequency-modulated TENS on blunt pressure pain in healthy human volunteers. Thirty-six participants received constant-frequency TENS (80 pps), frequency-modulated TENS (20 to 100 pps), and placebo (no current) TENS at a strong nonpainful intensity in a randomized cross-over manner. Pain threshold was taken from the forearm using pressure algometry. There were no statistical differences between constant-frequency TENS and frequency-modulated TENS after 20 minutes (OR = 1.54; CI, 0.29, 8.23, P = 1.0). Both constant-frequency TENS and frequency-modulated TENS wer...
Source: The Journal of Pain - September 30, 2009 Category: Materials Science Authors: Chih-Chung Chen, Mark I. Johnson Tags: Original Reports Source Type: journals

Alterations in Extracellular Levels of Gamma-Aminobutyric Acid in the Rat Basolateral Amygdala and Periaqueductal Gray During Conditioned Fear, Persistent Pain and Fear-Conditioned Analgesiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, expression of contextually induced fear- and pain-related behavior are accompanied by suppression of GABA release in the basolateral amygdala and dorsal periaqueductal gray, respectively, compared with non-fear, non-pain controls.Perspective: This study investigates alterations in levels of the neurotransmitter GABA simultaneously in the rat amygdala and periaqueductal grey during expression of pain- and fear-related behavior and fear-induced analgesia. The results enhance our understanding of the role of this neurotransmitter in pain, memory of pain and control of pain during fear. (Source: The Journal of Pain)
Source: The Journal of Pain - September 2, 2009 Category: Materials Science Authors: Kieran Rea, Yvonne Lang, David P. Finn Tags: Original Reports Source Type: journals

Comparative Cognitive and Subjective Side Effects of Immediate-Release Oxycodone in Healthy Middle-Aged and Older Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study measured the objective and subjective neurocognitive effects of a single 10-mg dose of immediate-release oxycodone in healthy, older (> 65 years), and middle-aged (35 to 55 years) adults who were not suffering from chronic or significant daily pain. Seventy-one participants completed 2 separate study days and were blind to medication condition (placebo, 10-mg oxycodone). Plasma oxycodone concentration peaked between 60 and 90 minutes postdose (P < .01) and pupil size, an indication of physiological effects of the medication, peaked at approximately 90 to 120 minutes postdose (P < .01). Significant declines in si...
Source: The Journal of Pain - September 2, 2009 Category: Materials Science Authors: Monique M. Cherrier, John K. Amory, Mary Ersek, Linda Risler, Danny D. Shen Tags: Original Reports Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

Self-Report of Alcohol Use for Pain in a Multi-Ethnic Community Sampleemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study examined the occurrence of alcohol use to manage pain in community-dwelling adults with tooth pain, jaw joint/face pain, and arthritis. Race/ethnicity, sex, and age were examined to determine their associations with alcohol use for pain. Community-dwelling adults from South Florida with tooth pain (n = 1,767), jaw joint/face pain (n = 1,199), or arthritis pain (n = 1,355) completed a structured telephone interview. Logistic regression models indicted that, similar to population rates, nonHispanic whites and males were the most likely to use alcohol to manage pain. In addition, alcohol use for pain was highest in...
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Authors: Joseph L. Riley, Christopher King Tags: Original Reports Source Type: journals

Struck From Behind: Maintaining Quality of Life With Chronic Low Back Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 38-year-old woman was the driver of a stopped car that was struck from behind by another vehicle. She developed sudden flexion and extension of her back, but without head trauma or change in level of consciousness. On the evening of the accident, she presented to the emergency room with severe mid and low back pain, and right knee pain, but was discharged with pain medications. One week following the accident, the pain became increasingly severe. For the past 6 months, she has been unable to work and is on disability. Chiropractic treatment, trigger-point injections, epidural injections and physical therapy, nonsteroidal...
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Authors: Allen Lebovits, Brian Hainline, Laura S. Stone, David A. Seminowicz, James T. Brunz, Richard W. Rosenquist, Penney Cowan Tags: Case Reviews in Pain Source Type: journals

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Central sensitization represents an enhancement in the function of neurons and circuits in nociceptive pathways caused by increases in membrane excitability and synaptic efficacy as well as to reduced inhibition and is a manifestation of the remarkable plasticity of the somatosensory nervous system in response to activity, inflammation, and neural injury. The net effect of central sensitization is to recruit previously subthreshold synaptic inputs to nociceptive neurons, generating an increased or augmented action potential output: a state of facilitation, potentiation, augmentation, or amplification. Central sen...
Source: The Journal of Pain - August 28, 2009 Category: Materials Science Authors: Alban Latremoliere, Clifford J. Woolf Tags: Critical Review Source Type: journals

Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in Chronic Fatigue Syndrome Patients But Not in Normal Subjectsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Chronic fatigue syndrome (CFS) is characterized by debilitating fatigue, often accompanied by widespread muscle pain that meets criteria for fibromyalgia syndrome (FMS). Symptoms become markedly worse after exercise. Previous studies implicated dysregulation of the sympathetic nervous system (SNS), and immune system (IS) in CFS and FMS. We recently demonstrated that acid sensing ion channel (probably ASIC3), purinergic type 2X receptors (probably P2X4 and P2X5) and the transient receptor potential vanilloid type 1 (TRPV1) are molecular receptors in mouse sensory neurons detecting metabolites that cause acute musc...
Source: The Journal of Pain - August 2, 2009 Category: Materials Science Authors: Alan R. Light, Andrea T. White, Ronald W. Hughen, Kathleen C. Light Tags: Original Reports Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

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(Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Tags: Frontmatter Source Type: journals

Erratumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The author names for “Validation of the Chronic Pain Acceptance Questionnaire (CPAQ) in Cantonese-speaking Chinese patients,” in J Pain 2008;9:823-832 (September 2008), were listed incorrectly. The correct list appears below. This does not affect the findings presented in the original article. (Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Tags: Erratum Source Type: journals

L2 Spinal Nerve–Block Effects on Acute Low Back Pain From Osteoporotic Vertebral Fractureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Elderly patients with osteoporosis sometimes experience lumbar vertebral fracture and may feel diffuse nonlocalized pain in the back, the lateral portion of the trunk, and the area surrounding the iliac crest. The pattern of sensory innervation of vertebral bodies remains unclear. Some sensory nerves from the L2 and L5 vertebral bodies may enter the paravertebral sympathetic trunks and reach the L2 dorsal root ganglion. Our randomized controlled study was to clarify the effect of L2 spinal nerve block on low back pain originating from acute osteoporotic lumbar vertebral fracture. Patients with low back pain origi...
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: Seiji Ohtori, Masaomi Yamashita, Gen Inoue, Kazuyo Yamauchi, Munetaka Suzuki, Sumihisa Orita, Yawara Eguchi, Nobuyasu Ochiai, Shunji Kishida, Masashi Takaso, Kazuhisa Takahashi Tags: Original Reports Source Type: journals

Does Pain Catastrophizing Moderate the Relationship Between Spinal Nociceptive Processes and Pain Sensitivity?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Existing evidence indicates that pain catastrophizing is associated with enhanced pain reports and lower pain threshold/tolerance levels, but is not significantly related to nociceptive flexion reflex (NFR) threshold in healthy and clinical pain samples. This suggests pain catastrophizing may modulate pain threshold at a supraspinal level without influencing descending modulation of spinal nociceptive inputs. To examine this issue further, the present study assessed NFR threshold, electrocutaneous pain threshold, and electrocutaneous pain tolerance, as well as subjective ratings of noxious stimuli in a sample of ...
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: Jamie L. Rhudy, Christopher R. France, Emily J. Bartley, Amy E. Williams, Klanci M. McCabe, Jennifer L. Russell Tags: Original Reports Source Type: journals

Cortical Reorganization in Primary Somatosensory Cortex in Patients With Unilateral Chronic Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Bodily representations of the primary somatosensory (SI) cortex are constantly modified according to sensory input. Increased input due to training as well as loss of input due to deafferentation are reflected as changes in the extent of cortical representations. Recent studies in complex regional pain syndrome (CRPS) patients have indicated that the chronic pain itself is associated with cortical reorganization. However, it is unclear whether the observed reorganization is specific for CRPS or if it can be detected also in other types of chronic pain. We therefore searched for signs of cortical reorganization in...
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: Nuutti Vartiainen, Erika Kirveskari, Katariina Kallio-Laine, Eija Kalso, Nina Forss Tags: Original Reports Source Type: journals

Reconstructing the Past on the Original Pain Recall Assessment Form (OPRA)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article presents the psychometric properties of a pain-assessment procedure. Our results suggest that the way people recall their symptoms is related to cognitive, emotional, and behavioral correlates of the pain experience. The importance of individual differences in overt and covert behaviors and their relationship to persistent pain complaints warrants further attention. (Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: Shane MacDonald, Steven J. Linton, Markus Jansson-Fröjmark Tags: Original Reports Source Type: journals

When Knee Pain Becomes Severe: A Nested Case-Control Analysis in Community-Dwelling Older Adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article describes what happens when the common symptom of mild knee pain in later life becomes significantly worse. The results may help clinicians understand the health impact, changes in patient appraisal and coping, and treatments that typically accompany this change in symptoms. (Source: The Journal of Pain)
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: George Peat, Elaine Thomas Tags: Original Reports Source Type: journals

An Insatiable Itchemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 77-year-old Caucasian female with a history of asthma, high cholesterol, degenerative joint disease, and stroke presents for assistance in managing post-zoster scalp itch. The patient had shingles approximately 2 years before the clinic visit with lesions in the left V1 distribution. She had a 7-day course of valacyclovir and the rash resolved within 2 weeks. After the rash resolved, she had about 2 weeks of pain, followed by constant, unrelenting pruritus in the same distribution. She had no current pain, numbness, or vision problems. The pruritus is a 3/10 with occasional exacerbations to 5/10. She gets temporary relie...
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: Gordon J. Wood, Tasuku Akiyama, E. Carstens, Anne Louise Oaklander, Gil Yosipovitch Tags: Case Reviews in Pain Source Type: journals

Understanding Fibromyalgia: Lessons from the Broader Pain Research Communityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Fibromyalgia (FM) is a chronic pain condition marked by centrally mediated augmentation of pain and sensory processes. Skepticism has marked the history of this condition, but more recent study has identified neurobiological underpinnings supporting many of the symptoms associated with this condition. Early research in FM had unprecedented latitude within the rheumatology community to borrow heavily from theory and methods being applied in chronic pain research more generally. These insights facilitated rapid advances in FM research, not the least of which was the abandonment of a peripheral focus in favor of stu...
Source: The Journal of Pain - July 28, 2009 Category: Materials Science Authors: David A. Williams, Daniel J. Clauw Tags: Critical Review Source Type: journals

Experimental Assessment of Affective Processing in Fibromyalgiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Fibromyalgia syndrome (FMS) is a chronic pain disorder associated with widespread musculoskeletal pain, tenderness, and fatigue. Additionally, correlational research suggests negative affect (eg, depression, anxiety) and deficits in positive affect may contribute to FMS symptomatology. However, well-controlled, experimental research is necessary to ascertain whether patients with FMS have problems in affective processing. The present study used a well-validated picture-viewing paradigm to evoke emotional responses in 17 patients with FMS and 17 sex- and age-matched healthy control participants. Each participant v...
Source: The Journal of Pain - July 27, 2009 Category: Materials Science Authors: Emily J. Bartley, Jamie L. Rhudy, Amy E. Williams Tags: Original Reports Source Type: journals

Structure of Posttraumatic Stress Disorder Symptoms in Pain and Pain-Free Patients Scheduled for Major Surgeryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Factor-analytic studies of the structure of posttraumatic stress disorder (PTSD) symptoms have yielded inconsistent results. One of the reasons for the inconsistency may be that PTSD is highly comorbid with other disorders; the observed factor structure might depend on the particular comorbid disorder. One such disorder is chronic pain. The goal of the present study was to investigate whether PTSD symptom structure differs between pain and pain-free patients scheduled to undergo major surgery. Four hundred and forty-seven patients who were approached 7 to 10 days prior to scheduled surgery completed the PTSD Chec...
Source: The Journal of Pain - July 26, 2009 Category: Materials Science Authors: Gabrielle M. Pagé, Valery Kleiman, Gordon J.G. Asmundson, Joel Katz Tags: Original Reports Source Type: journals

Translational Pain Research: Achievements and Challengesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: The achievements in both preclinical and clinical pain research over the past 4 decades have led to significant progress in clinical pain management. However, pain research still faces enormous challenges and there remain many obstacles in the treatment of clinical pain, particularly chronic pain. Translational pain research needs to involve a number of important areas including: 1) bridging the gap between pain research and clinical pain management; 2) developing objective pain-assessment tools; 3) analyzing current theories of pain mechanisms and their relevance to clinical pain; 4) exploring new tools for both...
Source: The Journal of Pain - July 22, 2009 Category: Materials Science Authors: Jianren Mao Tags: Critical Review Source Type: journals

Genetic Enhancement of Calcitonin Gene-Related Peptide-Induced Central Sensitization to Mechanical Stimuli in Miceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study we show central CGRP-induced mechanical allodynia that is enhanced by overexpression of RAMP1 in nervous system. These data suggest that hypersensitivity to CGRP could be a potential mechanism underlying central sensitization in migraine and point to CGRP-receptor antagonists as a possible therapy for other pain disorders. (Source: The Journal of Pain)
Source: The Journal of Pain - July 22, 2009 Category: Materials Science Authors: Blanca Marquez de Prado, Donna L. Hammond, Andrew F. Russo Tags: Original Reports Source Type: journals

Chemotherapy-Induced Peripheral Neuropathy as a Predictor of Neuropathic Pain in Breast Cancer Patients Previously Treated With Paclitaxelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Neuropathic pain (NP) remains difficult to control for a significant number of patients with cancer. Chemotherapy-induced peripheral neuropathy (CIPN) has been postulated as an initial stage in the development of NP. To assess whether CIPN (defined as National Cancer Institute Common Toxicity Criteria grade 2 or higher) was associated with NP, we conducted a survey of breast cancer patients who had participated in clinical trials of paclitaxel. Of the 430 potential respondents, 240 responded to the survey. Results showed that 64% experienced CIPN during paclitaxel treatment. Follow-up survey data revealed that 27...
Source: The Journal of Pain - July 13, 2009 Category: Materials Science Authors: Cielito C. Reyes-Gibby, Phuong Khang Morrow, Aman Buzdar, Sanjay Shete Tags: Original Reports Source Type: journals

Diagnosis-Specific Management of Somatoform Disorders: Moving Beyond “Vague Complaints of Pain”email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article highlights the appropriate diagnosis and treatment of somatoform disorders for patients with pain. In contrast to the majority of literature on the subject, the authors emphasize the importance of differential diagnosis between somatoform disorders as well as patient-specific and diagnosis-specific treatment. The authors argue that there has been an incorrect tendency to overgeneralize across disorders, an error that is magnified by the exceptional weakness of the somatoform category. (Source: The Journal of Pain)
Source: The Journal of Pain - July 13, 2009 Category: Materials Science Authors: Anne Dohrenwend, Jared Lyon Skillings Tags: Focus Article Source Type: journals

Effects of Oxytocin and Prolactin on Stress-Induced Bladder Hypersensitivity in Female Ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study presents evidence that systemic oxytocin has both analgesic and anxiolytic properties which may make it a potentially useful agent for patients with stress-exacerbated chronic-pain syndromes such as interstitial cystitis. These studies do not suggest a similar role for prolactin. (Source: The Journal of Pain)
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: L. Vandy Black, Timothy J. Ness, Meredith T. Robbins Tags: Original Reports Source Type: journals

Opioid Prescribing Practices in Chronic Pain Management: Guidelines Do Not Sufficiently Influence Clinical Practiceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: To examine the use of extended-release (ER) opioids relative to immediate-release (IR) opioids in chronic opioid prescription episodes, pharmacy claim data from a national health plan database were analyzed. Enrollees having at least 1 pharmacy claim for an opioid formulation between June 2003 and May 2006, and at least 1 year of continuous enrollment after their first observed pharmacy claim were included. Opioid prescription episodes were created by combining contiguous days of therapy, allowing for a maximum of 7 days between refills (≥8 d = new episode). Outcomes are reported in the form of probabilities an...
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: Timothy W. Victor, Nancy A. Alvarez, Errol Gould Tags: Original Reports Source Type: journals

Pain Coping in Latino Populationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Although there has been a rapid increase in Latino populations in the United States over the last 10 years, health research with Latino cultural groups is sorely lacking. In the area of pain-coping research, one consequence of the limited research is that very little is known about pain coping among Latinos. The purpose of this paper is to review the existing literature on pain coping in Latino populations, and to propose new directions for the future study of pain coping in Latino populations. This review is divided into 4 sections. In the first section, the challenges of defining Latino populations are discusse...
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: Lisa C. Campbell, Norah Andrews, Cindy Scipio, Brian Flores, Miriam H. Feliu, Francis J. Keefe Tags: Review Article Source Type: journals

Continuous Buprenorphine Delivery Effect in Streptozotocine-Induced Painful Diabetic Neuropathy in Ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study evaluated, through a multimodal approach, the analgesic effect of buprenorphine in an experimental rat model of painful DPN. Our results suggest a possible role for buprenorphine in the management of DPN-associated neuropathic pain. (Source: The Journal of Pain)
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: Annalisa Canta, Alessia Chiorazzi, Cristina Meregalli, Valentina Carozzi, Norberto Oggioni, Giuseppe Lauria, Raffaella Lombardi, Roberto Bianchi, Carla Porretta-Serapiglia, Guido Cavaletti Tags: Original Reports Source Type: journals

Both Happy and Sad Melodies Modulate Tonic Human Heat Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article provides new evidence that the valence of music is more crucial than mood in affective pain modulation. This finding gives impetus for health professionals to manage pain more effectively in patients with proper music. (Source: The Journal of Pain)
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: Huixuan Zhao, Andrew C.N. Chen Tags: Original Reports Source Type: journals

Development and Preliminary Testing of a Computerized Adaptive Assessment of Chronic Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report demonstrates that the CHRONIC PAIN-CAT is feasible for administration in a clinic. The application has the potential to improve pain assessment and help clinicians manage chronic pain. (Source: The Journal of Pain)
Source: The Journal of Pain - July 12, 2009 Category: Materials Science Authors: Milena D. Anatchkova, Renee N. Saris-Baglama, Mark Kosinski, Jakob B. Bjorner Tags: Original Reports Source Type: journals

Exploration of the Extent of Somato-Sensory Impairment in Patients with Unilateral Lateral Epicondylalgiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reveals the presence of bilateral pressure-pain hypersensitivity in patients with unilateral LE. On the contrary, thermal and vibration tests were not significantly different from controls. (Source: The Journal of Pain)
Source: The Journal of Pain - July 10, 2009 Category: Materials Science Authors: Josué Fernández-Carnero, César Fernández-de-las-Peñas, Michel Sterling, Tina Souvlis, Lars Arendt-Nielsen, Bill Vicenzino Tags: Original Reports Source Type: journals

Bilateral Widespread Mechanical Pain Sensitivity in Women With Myofascial Temporomandibular Disorder: Evidence of Impairment in Central Nociceptive Processingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reveals the presence of bilateral and widespread pressure-pain hypersensitivity in women with myofascial TMD, suggesting that widespread central sensitization is involved in myofascial TMD. This finding has implications for development of management strategies. (Source: The Journal of Pain)
Source: The Journal of Pain - July 10, 2009 Category: Materials Science Authors: César Fernández-de-las-Peñas, Fernando Galán-del-Río, Josué Fernández-Carnero, Jorge Pesquera, Lars Arendt-Nielsen, Peter Svensson Tags: Original Reports Source Type: journals

Sound Stress–Induced Long-Term Enhancement of Mechanical Hyperalgesia in Rats Is Maintained by Sympathoadrenal Catecholaminesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present data showing mechanical hyperalgesia persisting for up to 28 days after exposure to sound stress, with evidence that the sympathoadrenal axis mediator epinephrine plays a major role. These findings could have clinical implications with regard to novel potential treatments for chronic widespread pain syndromes, such as fibromyalgia. (Source: The Journal of Pain)
Source: The Journal of Pain - July 2, 2009 Category: Materials Science Authors: Sachia G. Khasar, Olayinka A. Dina, Paul G. Green, Jon D. Levine Tags: Original Reports Source Type: journals

Internal Qigong for Pain Conditions: A Systematic Reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objective of this systematic review was to assess the evidence for the effectiveness of internal qigong as a treatment option for pain conditions. Nineteen databases were searched through to February 2009. Controlled clinical trials testing internal qigong in patients with pain of any origin assessing clinical outcome measures were considered. Trials using any type of internal qigong and control intervention were included. The selection of studies, data extraction, and validation were performed independently by 2 reviewers. Four randomized clinical trials (RCTs) and 3 controlled clinical trials met all inclusion criter...
Source: The Journal of Pain - June 26, 2009 Category: Materials Science Authors: Myeong Soo Lee, Max H. Pittler, Edzard Ernst Tags: Review Article Source Type: journals