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319 records returned

How academic is internal medicine in the Netherlands? A bibliometric analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19915224 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Levi M Tags: Neth J Med Source Type: journals

Transfusion-related acute lung injury: a change of perspective.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, TRALI has emerged as the leading cause of transfusion-related mortality, presumably as a consequence of reaching international agreement on defining TRALI with subsequent increased recognition and reporting of TRALI cases. Specific patient populations such as critically ill patients have an increased risk of developing TRALI, which may be explained by the two-event hypothesis. The first event is the underlying condition of the patient resulting in priming of neutrophils. The second event ...
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Vlaar AP, Schultz MJ, Juffermans NP Tags: Neth J Med Source Type: journals

Immune reconstitution inflammatory syndrome: immunopathogenesis, risk factors, diagnosis, treatment and prevention.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Immune reconstitution inflammatory syndrome (IRIS) occurs in a subpopulation of HIV-infected patients after the introduction of antiretroviral therapy (ART). The purpose of this review is to describe the immunopathogenesis, risk factors, diagnostic problems, treatment and prevention of IRIS. A literature search was performed and finally 15 recent articles were selected. The immunopathogenesis of IRIS is characterised by a dysbalanced restoration of the immune system resulting in pathological inflammation. Risk factors are low baseline CD4-cell count, an excellent virological response, an increased antigenic burden of a...
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Beishuizen SJ, Geerlings SE Tags: Neth J Med Source Type: journals

The hypothalamus-pituitary-thyroid axis in critical illness.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The thyroid axis is comprised of thyrotropin-releasing hormone (TRH) at the level of the hypothalamus which stimulates the pituitary to release thyrotropin (TSH). TSH in turn stimulates the thyroid to secrete the pro-hormone thyroxin (T4) and to a lesser extent the receptor active hormone tri-iodothyronine (T3). The majority of circulating T3 is generated by peripheral conversion of T4 by the intracellular iodothyronine deiodinases. Thyroid hormone (TH) is transported over the cell membrane by specific TH transporters such as monocarboxylate transporter 8 (MCT8). After transport and metabolisation in the cell, T3 can i...
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Mebis L, van den Berghe G Tags: Neth J Med Source Type: journals

Prognostic value of cardiac troponin I in patients with COPD acute exacerbation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In patients hospitalised for acute COPD exacerbations, elevated baseline and peak cTnI were associated with a greater need for noninvasive ventilatory support and were significant predictors of 18-month overall survival. PMID: 19915228 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Martins CS, Rodrigues MJ, Miranda VP, Nunes JP Tags: Neth J Med Source Type: journals

Takotsubo cardiomyopathy following radioiodine therapy for toxic multinodular goitre.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 73-year-old man with a toxic multinodular goitre, which was treated with radioiodine therapy (I-131) without pretreatment with an antithyroid drug. Four weeks later he presented with rapidly progressive dyspnoea and a significant increase in free thyroxin. The electrocardiogram showed ST -segment elevation, and echocardiography demonstrated apical akinesia and a left ventricular ejection fraction of only 25%. However, direct coronary catheterisation showed no evidence of coronary artery disease. Left ventricular angiography showed apical ballooning consistent with the diagnosis of takotsubo cardiomyopathy. F...
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: van de Donk NW, America YG, Zelissen PM, Hamer BJ Tags: Neth J Med Source Type: journals

Pulmonary coccidioidomycosis: import illness and the importance of travel history.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 35-year-old man presented at the outpatient department of pulmonary diseases with fever, rhinitis and coughing. He had recently been on holiday in California. Except for a body temperature of 39.7 degrees C there were no other abnormal findings at the physical examination. Chest X-ray showed a consolidation in the left upper lobe. Under antibiotic treatment his clinical condition deteriorated. Coccidioidomycosis was the suspected diagnosis and confirmed by the results of CT scanning and culture of bronchoalveolar lavage fluid. Treatment with itraconazole resulted in lasting improvement. The case stipulates the import...
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Indhirajanti S, Maartense E, Posthuma EF, Pannekoek BJ, Vreede RW Tags: Neth J Med Source Type: journals

A patient with neck pain and fever. Combined prevertebral and intraspinal abscess in a patient with a de novo HIV infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19915231 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: ter Avest E, Uyttenboogaart M, Dorgelo J, ter Maaten JC Tags: Neth J Med Source Type: journals

Something fishy. Fish tank granuloma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19915232 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Ramautarsing R, den Hollander J, van Meurs T Tags: Neth J Med Source Type: journals

Yellow-white lesions in the upper gastrointestinal tract. Gastric xanthelasmas.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19915233 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - November 1, 2009 Category: Journals (General) Authors: Jansen HJ, van Krieken JH, Römkens TE Tags: Neth J Med Source Type: journals

Early recognition of critically ill patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841482 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Schultz MJ Tags: Neth J Med Source Type: journals

Early identification of patients with or at risk of acute lung injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acute lung injury (ALI ) and its more severe form, acute respiratory distress syndrome (ARDS ), are important critical care syndromes for which the treatment options are limited once the condition is fully established. Enormous basic and clinical research efforts have led to improvements in supportive treatment, but surprisingly little has been done on the prevention of this devastating syndrome. The development and progression of ALI /ARDS may be triggered by various intrahospital exposures including but not limited to transfusion, aspiration, mechanical ventilation, certain medications and delayed treatment of shock ...
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Ahmed A, Kojicic M, Herasevich V, Gajic O Tags: Neth J Med Source Type: journals

Rhabdomyolysis: a review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this review is to describe the aetiological spectrum and pathophysiology of rhabdomyolysis, the clinical and biological consequences of this syndrome and to provide an appraisal of the current data available in order to facilitate the prevention, early diagnosis and prompt management of this condition. PMID: 19841484 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Khan FY Tags: Neth J Med Source Type: journals

A systematic review of selective and non-selective beta blockers for prevention of vascular events in patients with acute coronary syndrome or heart failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Additional beta2-receptor blockade may be more effective than beta1-receptor blockade alone in preventing total mortality and vascular events in patients with ACS or, to a lesser extent, HF . However, only a few studies directly compared beta blockers, and indirect comparisons were subject to heterogeneity, which weakens firm conclusions. PMID: 19841485 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: de Peuter OR, Lussana F, Peters RJ, Büller HR, Kamphuisen PW Tags: Neth J Med Source Type: journals

Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Heart failure is a rare but life-threatening manifestation of cardiac involvement in SLE. Long-term outcome can be excellent when aggressive treatment is instituted promptly. PMID: 19841486 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: van der Laan-Baalbergen NE, Mollema SA, Kritikos H, Schoe A, Huizinga TW, Bax JJ, Boumpas DT, van Laar JM Tags: Neth J Med Source Type: journals

Complete remission of severe idiopathic cold urticaria on interleukin-1 receptor antagonist (anakinra).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We describe the first case of IL-1RA treatment in idiopathic cold urticaria with good response. Anakinra had no effect on the progression of her symptoms of ALS. PMID: 19841487 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Bodar EJ, Simon A, de Visser M, van der Meer JW Tags: Neth J Med Source Type: journals

A 72-year-old man with a rapidly progressive sepsis caused by a rare but life-threatening infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841488 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Bech AP, Komdeur R Tags: Neth J Med Source Type: journals

A woman with a swollen neck.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841489 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: van Kuilenburg JT, van Niekerk J, Sinnige H, de Jager CP Tags: Neth J Med Source Type: journals

A patient with haemolytic anaemia diagnosed after thirty years.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841490 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Vlasveld LT, Franck PF, Castel A Tags: Neth J Med Source Type: journals

Internal medicine residents' knowledge about sepsis: effects of a teaching intervention.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The short- and long-term effects of a single teaching intervention for internal medicine residents are not known. Since sepsis is a prevalent and important disease and both therapeutic and diagnostic interventions have been protocolized, we investigated the effects of a sepsis-based single teaching intervention. A prospective before-and-after education study was performed among residents who attended a regional professional training for internal medicine. All residents who participated were invited to complete a questionnaire about the assessment of symptoms and the diagnosis and treatment of sepsis. The questionnaire ...
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Tromp M, Bleeker-Rovers CP, van Achterber T, Kullberg BJ, Hulscher M, Pickkers P Tags: Neth J Med Source Type: journals

Microscopic colitis and endoscopy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841492 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Koulaouzidis A Tags: Neth J Med Source Type: journals

Unexpected cause of iron deficiency detected by capsule endoscopy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841493 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - September 30, 2009 Category: Journals (General) Authors: Visser L, Lieshout L Tags: Neth J Med Source Type: journals

Novel antibodies in the treatment of non-Hodgkin's lymphoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Monoclonal antibodies (mAbs) have revolutionised the treatment of malignancies, especially non-Hodgkin's lymphoma (NHL). Antibody-based therapies target tumour cells expressing a specific antigen while sparing the majority of normal cells leading to a decrease in treatment-associated toxicity. Rituximab, a monoclonal antibody directed against CD20 on B cells, was the first monoclonal antibody to be approved by the US Food and Drug Association (FDA) in 1997 for the treatment of patients with relapsed/refractory, follicular or low-grade NHL . However, it was soon realised that not all patients respond to rituximab therap...
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Bhat SA, Czuczman MS Tags: Neth J Med Source Type: journals

Assisted reproductive technologies to establish pregnancies in couples with an HIV-1-infected man.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article aims to summarise the current state of the art of assisted reproductive technologies for couples with an HIV -1-infected man and to discuss current trends and dilemmas in the treatment of these couples. PMID: 19767658 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: van Leeuwen E, Repping S, Prins JM, Reiss P, van der Veen F Tags: Neth J Med Source Type: journals

Where the immune response meets the vessel wall.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Immune-mediated inflammatory diseases (IMIDs), including rheumatoid arthritis and spondyloarthritis, are associated with increased cardiovascular morbidity and mortality, independent of the established cardiovascular risk factors. The chronic inflammatory state, a hallmark of IMIDs, is considered to be a driving force for accelerated atherogenesis. Consequently, aggressive control of disease activity has been suggested to be instrumental for cardiovascular risk reduction. Specific guidelines for cardiovascular risk reduction in patients with IMIDs, particularly rheumatoid arthritis, are lacking, largely due to the abse...
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Bisoendial RJ, Stroes ES, Tak PP Tags: Neth J Med Source Type: journals

Blood pressure response to moderate physical activity is increased in obesity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objective: To test the hypothesis that in young, normotensive obese subjects, physical activity at a fixed, moderate workload, causes a more pronounced hypertensive effect than in lean subjects. Patients and methods: 24 subjects (12 with BMI >30 kg/m2, 12 with BMI. PMID: 19767664 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Burger JP, Serne EH, Nolte F, Smulders YM Tags: Neth J Med Source Type: journals

Complete remission of MDS RAEB following immunosuppressive treatment in a patient with Sweet's syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a patient with myelodysplastic syndrome (MDS), classified as refractory anaemia with excess of blasts-2, and histiocytoid Sweet's syndrome. The skin lesions disappeared after initiation of corticosteroids and doxycycline. Remarkably, two months later a complete remission of the MDS occurred. Fourteen months later both the skin lesions and the MDS relapsed. Antileukaemic activity following reversion of the impaired cellular immunity due to an increased number of natural killer cells in his bone marrow may be responsible for this rare event. Inhibition of T-cell mediated myelosuppression by corticosteroids or a ...
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Ten Oever J, Kuijper PH, Kuijpers AL, Dercksen MW, Vreugdenhil G Tags: Neth J Med Source Type: journals

Splenectomy-induced long-term remission in a patient with multicentric Castleman's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient with multicentric CD in complete remission, eight years after a splenectomy without any other systemic treatment. We discuss the possible mechanism causing this long episode of complete remission in this patient. PMID: 19767666 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Bos MM, van den Berg LM, van Leeuwen AW, Posthuma EF Tags: Neth J Med Source Type: journals

The Dutch EPS Registry: Increasing the knowledge of encapsulating peritoneal sclerosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Encapsulating peritoneal sclerosis (EPS) is a rare condition characterised by fibrotic thickening of the visceral peritoneum, leading to encapsulating of the intestines with partial or total intestinal obstruction. EPS is a serious complication of peritoneal dialysis (PD) with high morbidity and a mortality exceeding 50%. At present, there is uncertainty concerning the incidence and the risk factors involved in the development of EPS . To address these questions a nationwide registry has been initiated. The primary goals of the registry are to record the incidence of EPS and investigate the association of different var...
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Korte MR, Boeschoten EW, Betjes MG, Behalf Of The Eps Registry O Tags: Neth J Med Source Type: journals

The role of rituximab in a case of EBV-related lymphoproliferative disease presenting with haemophagocytosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19767670 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - August 31, 2009 Category: Journals (General) Authors: Bosman G, Langemeijer SM, Hebeda KM, Raemaekers JM, Pickkers P, van der Velden WJ Tags: Neth J Med Source Type: journals

Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma:moving targets.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767656 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: van Oers MH Tags: Neth J Med Source Type: journals

Intermitting umbilical pain, fever and weight loss in an otherwise healthy 65-year-old male.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767660 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: Nieuwdorp M, Nio CY, Bartelsman JF, Hoekstra JB Tags: Neth J Med Source Type: journals

An ulcer of the foot.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767661 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: Pereyra-Rodríguez JJ, Gacto-Sánchez P Tags: Neth J Med Source Type: journals

Periorbital oedema.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767662 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: van Hasselt W, Schreuder RM, Houwerzijl EJ Tags: Neth J Med Source Type: journals

Purple urine bag syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767663 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: van Iersel M, Mattijssen V Tags: Neth J Med Source Type: journals

Improved survival for patients with large B-cell lymphoma after introduction of rituximab.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The introduction of rituximab in the treatment of DLB CL with CHOP chemotherapy has resulted in a significantly better prognosis for patients with DLBCL, treated in the Reinier de Graaf Gasthuis in Delft. PMID: 19767667 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: Rodenburg EM, Maartense E, Posthuma EF Tags: Neth J Med Source Type: journals

Responding to adverse events.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available. PMID: 19767669 [PubMed - as supplied by publisher] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - July 31, 2009 Category: Journals (General) Authors: Wollersheim H Tags: Neth J Med Source Type: journals

Endocrine laboratory testing: why so complex?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19687517 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Levi M Tags: Neth J Med Source Type: journals

CD20-targeted therapy: a breakthrough in the treatment of non-Hodgkin's lymphoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Targeting the CD20 antigen on B lymphocytes with the monoclonal antibody rituximab has greatly improved the outcome of patients with B-cell malignancies. Despite the success of rituximab, resistance occurs in about half of the patients, resulting in non-response to treatment or early relapse of the original disease. A better understanding of the mechanism of rituximab resistance has lead to the development of novel, improved anti-CD20 antibodies. This review describes the development of CD20-targeted therapy from its historical background towards the next generation of anti-CD20 monoclonal antibodies and explains new s...
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: van Meerten T, Hagenbeek A Tags: Neth J Med Source Type: journals

Investigating obscure gastrointestinal bleeding: capsule endoscopy or double balloon enteroscopy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The possibility to visualise the small bowel has dramatically improved with the introduction of capsule endoscopy (CE) and double balloon enteroscopy (DBE). CE and DBE have become standard practice in investigating suspected diseases of the small bowel. An important reason to perform small bowel investigations is obscure gastrointestinal bleeding. To investigate obscure gastrointestinal bleeding, some advocate performing CE while others recommend DBE . In this systematic review, we provide an overview of studies in which patients with obscure gastrointestinal bleeding underwent both CE and DBE . These data show that CE...
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Westerhof J, Weersma RK, Koornstra JJ Tags: Neth J Med Source Type: journals

Cell-derived microvesicles and cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Blood and other body f luids contain cell-derived microvesicles. The presence of microvesicles in cancer patients was already noticed in the late 1970s. Since then, the prothrombotic state in cancer patients has invariably been associated with the presence of such microvesicles. More recently, a growing body of evidence supports an important contribution of microvesicles to cancer cell survival, invasiveness and metastases. Here, we will present an overview of the many contributions of microvesicles to cancer development and progression. In addition, their role in risk stratification and treatment of cancer patients is...
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: van Doormaal FF, Kleinjan A, Di Nisio M, Büller HR, Nieuwland R Tags: Neth J Med Source Type: journals

Evaluation of endocrine tests. D: the prolonged fasting test for insulinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In our centre, the prolonged fasting test defined as a positive Whipple's triad in combination with an insulin/C-peptide ratio <1 had a sensitivity of 88.9% and a specificity of 100% for the diagnosis of insulinoma. PMID: 19687521 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: van Bon AC, Benhadi N, Endert E, Fliers E, Wiersinga WM Tags: Neth J Med Source Type: journals

Diabetes specialist nurse as main care provider for patients with type 2 diabetes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: NSD s using treatment protocols are able to provide effective care for patients with DM 2, comparable with the care provided by an internist, with respect to clinical parameters, and superior with respect to healthcare costs and patient satisfaction. PMID: 19687522 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Houweling ST, Kleefstra N, van Hateren KJ, Kooy A, Groenier KH, Ten Vergert E, Meyboom-de Jong B, Bilo HJ, Tags: Neth J Med Source Type: journals

A rare case of heterotopic pancreas in the stomach which caused closed perforation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of a 19-year-old female patient with a perforated heterotopic pancreas of the gastric antrum. There have been no reports describing perforated gastric heterotopic pancreas and it should always be considered in the differential diagnosis of gastric masses and acute abdomen. PMID: 19687523 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Gurocak B, Gokturk HS, Kayacetin S, Bakdik S Tags: Neth J Med Source Type: journals

Abdominal pain, low grade fever and persistent shock.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19687524 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Woei-A-Jin FJ, Kapiteijn E, Nortier JW, Osanto S Tags: Neth J Med Source Type: journals

A woman with a painful hip.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19687525 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: van der Valk M, Godfried MH Tags: Neth J Med Source Type: journals

A patient with redness and swelling of his foot: rheumatoid arthritis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19687526 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Langemeijer SM, van Deuren M Tags: Neth J Med Source Type: journals

Turning green with shock.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19687527 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Wiersinga WJ, Limmathurotsakul D, Cheng AC Tags: Neth J Med Source Type: journals

Current awareness of delirium in the intensive care unit: a postal survey in the Netherlands.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In the Netherlands, delirium is considered an important problem in the ICU, although its incidence is estimated to be low by the ICU team. The diagnosis of delirium is most frequently established by a geriatrician or psychiatrist after consultation, while diagnostic instruments are infrequently used. Efforts should be undertaken to implement delirium protocols and a routinely applied diagnostic instrument in the ICU. PMID: 19687528 [PubMed - in process] (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: Cadogan FL, Riekerk B, Vreeswijk R, Rommes JH, Toornvliet AC, Honing ML, Spronk PE Tags: Neth J Med Source Type: journals

Second national serum bank for population-based seroprevalence studies in the Netherlands.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In 2006/2007 a large serum bank was established by means of a cross-sectional population-based study. This serum bank will be used to evaluate the Dutch national immunisation programme (NIP) by serosurveillance and additional immunological and epidemiological research. In this paper we describe the design of this population-based cross-sectional serosurvey and report the participation rates as well as general characteristics of the study population. A similar serum bank was collected in 1995/1996. Dutch inhabitants (aged 0-79 years, men and women) were invited from 40 municipalities throughout the country and also from...
Source: The Netherlands Journal of Medicine - June 30, 2009 Category: Journals (General) Authors: van der Klis FR, Mollema L, Berbers GA, de Melker HE, Coutinho RA Tags: Neth J Med Source Type: journals