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Scientists identify DNA that regulates antibody productionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of antibody genes that makes such a precise and coordinated attack possible. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 19, 2009 Category: Biomedical Science Source Type: organizations

Shaham and Chalasani named winners of 2009 Blavatnik AwardsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Associate Professor Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani, who were named finalists in the third annual competition in September, were honored last night with six other winners at the New York Academy of Sciences’ Science and the City Gala. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 17, 2009 Category: Biomedical Science Source Type: organizations

Imaging study shows HIV particles assembling around its genomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The genesis of one the planet’s most lethal viruses, HIV, has been caught on tape. New imaging experiments show individual HIV genomes — strands of RNA — docking on the inner membrane of an infected cell wall as they are ensconced by HIV structural proteins. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 16, 2009 Category: Biomedical Science Source Type: organizations

Two proteins act as molecular tailors in DNA repairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
On average, our cells encounter a very lethal form of DNA damage 10 times a day. Lucky for us, we have the capacity to repair each and every one of them. New research now reveals exactly how two well-known proteins are involved in the process, a finding that not only helps shed light on cancer but also on how our cells maintain the integrity of our genome. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 12, 2009 Category: Biomedical Science Source Type: organizations

High fat diet increases inflammation in the mouse colonEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In mice fed a diet high in fat and low in fiber, vitamin D and calcium — the so-called Western diet — expression of a series of genes collectively associated with immune and inflammatory responses was altered. The findings show that a Western diet induces oxidative stress and alters immune responses in the colon of mice long before tumors occur. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 11, 2009 Category: Biomedical Science Source Type: organizations

Rockefeller joins first national research study recruitment registryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rockefeller University has joined more than 50 U.S. research institutions in making information about its clinical research trials available on ResearchMatch, the country’s first registry for recruiting research participants. The secure Web site offers a free and safe way for volunteers to connect with thousands of researchers who are conducting research on a wide range of diseases. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 10, 2009 Category: Biomedical Science Source Type: organizations

Scientists reveal a new mechanism that increases atherosclerosis in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
For all the good it does, a liver protein that senses and gets rid of drugs and pollutants from our body has a downside. For the first time, it has been shown that when it is chronically activated, the protein, called PXR, rejiggers how cholesterol is processed in the liver and increases the risk of developing atherosclerosis. The work has direct clinical consequences to patients under long-term treatment of PXR-activating drugs, including several antibiotic and anti-cancer medications — and your daily latte. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 4, 2009 Category: Biomedical Science Source Type: organizations

Immune system uses a “leash” to restrict HIV’s spreadEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research shows how an antiviral protein, tetherin, lashes newborn viral particles to infected cells, slowing the spread of infection. Understanding how this immune system defense works against HIV, Ebola and other deadly viruses could lead to better antiviral therapies. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 3, 2009 Category: Biomedical Science Source Type: organizations

Disrupting sleep causes problems for the body and brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Modern life disrupts our natural sleep cycles with shift-work, jet lag and ubiquitous electric lighting, among other things. New research in mice suggests that the resulting disturbance of nature’s circadian rhythms could have major effects on the body and brain, from a slowing of metabolism to impaired thinking and poor impulse control. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 26, 2009 Category: Biomedical Science Source Type: organizations

2009 Pearl Meister Greengard Prize goes to pioneering geneticistEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The 2009 Pearl Meister Greengard Prize recognizes Suzanne Cory, a world-renowned geneticist and pioneering scientific leader. The first woman to serve as director of Australia’s prestigious Walter and Eliza Hall Institute, she has been an influential force in shaping science policy in her nation. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 22, 2009 Category: Biomedical Science Source Type: organizations

Checkered history of mother and daughter cells explains cell cycle differencesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In preparing to divide, mother and daughter cells use different gears and levers to regulate their genes. A collaboration between two geneticists and their labs now reveals that this difference in gene expression ultimately affects the protein CLN3, the levels of which certify whether a cell is ready to commit to another grueling round of cell division. The work sets a new compass point for studying how cell division may go awry in different types of cancer. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 20, 2009 Category: Biomedical Science Source Type: organizations

Rockefeller postdoc named finalist for Eppendorf & Science Prize for NeurobiologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A panel of distinguished scientists and editors have named postdoc Max Heiman a finalist for the Eppendorf & Science Prize for Neurobiology. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 19, 2009 Category: Biomedical Science Source Type: organizations

Elaine Fuchs to receive 2010 L'Oréal-UNESCO prize for women scientistsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Elaine Fuchs — one of five women scientists around the world selected by the L’Oréal-UNESCO For Women in Science partnership to receive the 2010 L’Oréal-UNESCO Awards in the Life Sciences — is honored for her contributions to our knowledge of skin biology and skin stem cells. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 14, 2009 Category: Biomedical Science Source Type: organizations

Immunologist Michel Nussenzweig elected to Institute of MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The head of Rockefeller University’s Laboratory of Molecular Immunology, Nussenzweig’s considerable contributions to the field of immunology include insights into how autoimmune diseases progress and the development of methods that may lead to dendritic-cell vaccines. Nussenzweig is one of 14 current Rockefeller researchers who are members of the Institute of Medicine. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 12, 2009 Category: Biomedical Science Source Type: organizations

Transgenic songbirds provide new tool to understand the brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Over the decades, scientists have learned a lot about the basic life processes shared by many animals — including people — by manipulating the DNA of the “lower” species, such as mice and worms. But to date, they have been unable to readily probe the genetic contribution to one higher cognitive capacity of particular interest — the ability to learn language from one another. Now scientists have worked out a method for altering the genes of the zebra finch, one of the handful of social animals that learn to “speak” in a way that is analogous to humans. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - October 5, 2009 Category: Biomedical Science Source Type: organizations

Clinical study to probe genetic link to Salmonella diseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Unusual symptoms of Salmonella infection in certain children may be caused a genetic mutation, according to researchers at The Rockefeller University Hospital, where a new clinical study is examining the immune profiles of affected children. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 28, 2009 Category: Biomedical Science Source Type: organizations

“Promiscuous” protein interactions found in the nuclear pore complexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The NPC is the only way in or out of a cell’s nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further insights into the design of this evolutionarily ancient and little-understood transport machinery. The findings suggest that the nuclear pore complex takes on different formations to carry out its function. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 28, 2009 Category: Biomedical Science Source Type: organizations

Obesity researcher wins Keio Medical Science PrizeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Jeffery Friedman shares the 14th Keio Medical Science Prize, awarded annually to researchers for outstanding achievements in the fields of life sciences and medicine, for the "discovery of leptin and the study of its physiological functions.” (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 28, 2009 Category: Biomedical Science Source Type: organizations

New model suggests how the brain might stay in balanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Physicists have theorized for decades about how neural networks might be able to accomplish the incredibly complex calculations the human brain performs all the time. But simply stabilizing such a powerful organic computer made up of 100 billion neurons and trillions of interconnections is no small matter. A new model proposes that the brain could use about half of its connections just to maintain a delicate balance of excitation and inhibition. And keep from going haywire. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 24, 2009 Category: Biomedical Science Source Type: organizations

Rockefeller virologists and MIT tissue engineers receive $5.8 million NIH grant to study hepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Provided through the National Institutes of Health’s inaugural Transformative R01 grant program — a groundbreaking initiative designed to encourage high-risk research — the grant will run for five years and will fund efforts to elucidate the notoriously complex mechanisms underlying hepatitis B and C virus infection. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 24, 2009 Category: Biomedical Science Source Type: organizations

New Innovator Award goes to cancer researcher Sohail TavazoieEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
One of Rockefeller’s newest faculty recruits, Tavazoie aims to identify small pieces of RNA, known as microRNAs, that may signal a high potential for metastasis or that can effectively distinguish between cancers that will be responsive to chemotherapy and those that would be better candidates for alternative and experimental therapies. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 24, 2009 Category: Biomedical Science Source Type: organizations

Elaine Fuchs receives National Medal of ScienceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Elaine Fuchs, Rebecca C. Lancefield Professor, is being honored “for her pioneering use of cell biology and molecular genetics in mice to understand the basis of inherited diseases in humans and her outstanding contributions to our understanding of the biology of skin and its disorders, including her notable investigations of adult skin stem cells, cancers and genetic syndromes.” (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 17, 2009 Category: Biomedical Science Source Type: organizations

Two Rockefeller scientists named finalists for Blavatnik Awards for Young ScientistsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Associate Professor and head of laboratory Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani are finalists in the third annual competition administered by the New York Academy of Sciences. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 14, 2009 Category: Biomedical Science Source Type: organizations

To better control Chagas disease, focus funds more efficiently, scientists sayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Controlling the bug that causes Chagas disease, a chronic infection of 10 million people worldwide with no available cures or vaccines, is the primary goal of public health officials in the developing world. New research suggests that insecticide spraying should be concentrated during the seasons when bugs disperse over long distances to make the best use of limited resources. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 9, 2009 Category: Biomedical Science Source Type: organizations

Two proteins enable skin cells to regenerateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Skin cells that have lost their luster flake off and are replaced by new ones that push their way up to the surface. In new research that further dissects how stem cells specialize into tissue cells, scientists now show how these new skin cells arise — work that may one day hold promise for burn victims. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 3, 2009 Category: Biomedical Science Source Type: organizations

New technique allows scientists to penetrate yeast cells’ hard exteriorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Injections are a useful tool for cell biologists. They allow researchers to administer proteins and chemicals directly to the inside of a single cell. A new technique, developed at Rockefeller University, makes this possible for the first time in cells that were previously considered too hard to be penetrated by traditional methods. By using a micropipette like a saw and combining it with a small electric motor, scientists have now successfully administered fluorescent proteins to yeast cells. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - September 3, 2009 Category: Biomedical Science Source Type: organizations

New research supports model for nuclear pore complexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The pores that control what passes in and out of the cell nucleus play a crucial role in the cell’s metabolism and signaling. Defects in structure and function of these gatekeepers, known as nuclear pore complexes, can have lethal consequences. New research reveals secrets about what may be a key design feature of these structures, a flexibility enabling the import and export of large molecules. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - August 18, 2009 Category: Biomedical Science Source Type: organizations

Scientists identify stomach’s timekeepers of hungerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The problem with dieting is that it leaves you hungry. But scientists have now identified specific cells in the stomach that are behind the body’s craving for food. In new research that has implications for the treatment of obesity, scientists have shown that these cells release the hormone ghrelin, which in animals causes foraging behavior even when they’re not hungry. The findings could help researchers develop drugs that would curb dieters’ appetites before that first bite. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - August 13, 2009 Category: Biomedical Science Source Type: organizations

Anthrax bacteria conspire with viruses to stay aliveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research suggests that anthrax-causing bacteria work synergistically with viruses to extend each other’s life spans. The work puts scientists on a new playing field in the fight against biological warfare and antibiotic-resistance, and also calls into question the degree to which our genomes are the sole masters of our fates. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - August 12, 2009 Category: Biomedical Science Source Type: organizations

Model suggests how life’s code emerged from primordial soupEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It would seem a stunning improbability for a whirlwind to spin through a junkyard and leave behind a fully assembled jumbo jet. This colorful metaphor by astronomer Fred Hoyle points out the difficulties encountered by scientists when they try to understand how Life could have emerged billions of years ago. Researchers at Rockefeller University now show how crude pieces of a genetic system could self-assemble and generate the rules of Life’s most fundamental code. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - August 7, 2009 Category: Biomedical Science Source Type: organizations

Acute stress improves working memory, research suggestsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Stress is no fun. Chronic stress can ruin your health. But the body’s response to troubling situations is not without benefit. New research shows that after a brief encounter with a stressful scenario, the resulting acute stress actually makes you smarter. Or at least it improves the working memory of rats by ramping up production of neurotransmitters in the prefrontal cortex, a key region of the brain controlling emotion and cognition. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 27, 2009 Category: Biomedical Science Source Type: organizations

Tenure awarded to RNA researcher Thomas TuschlEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The university promotes a biochemist who researches RNA interference (RNAi), the process by which small RNA molecules interfere with gene expression. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 24, 2009 Category: Biomedical Science Source Type: organizations

Songbirds’ elaborate cries for food show first signs of vocal learningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
How a handful of social animals ever learned to actively style their vocal communication is a question that has dogged biologists for generations. New research in chipping sparrows suggests that the talent originally appeared in these songbirds as a competition for food among siblings and later evolved into vocal imitation used in territorial defense and courtship. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 23, 2009 Category: Biomedical Science Source Type: organizations

New imaging studies reveal mechanics of neuron migrationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the developing brain, generations of young neurons undergo a staged migration, with the earliest-born cells staying relatively close to their birthplace and subsequent generations traveling further, ultimately stratifying into six neuronal layers in the mature brain. For the first time, imaging studies have identified the “motors” that propel this unique form of cell migration, giving insight into the delicate layering of the brain that underlies the formation of synaptic circuitry. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 22, 2009 Category: Biomedical Science Source Type: organizations

Head of Rockefeller University Press named 2009 SPARC InnovatorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mike Rossner, executive director of The Rockefeller University Press, has been named the newest SPARC Innovator by the Scholarly Publishing and Academic Resources Coalition. Announced last week, the award honors Rossner for his work as a proponent of data integrity in and wider public access to scientific publishing. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 14, 2009 Category: Biomedical Science Source Type: organizations

By manipulating oxygen, scientists coax bacteria into a waveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bacteria know that they are too small to make an impact individually. So they wait; they multiply, and then they engage in behaviors that are only successful when all cells participate in unison. There are hundreds of behaviors that bacteria carry out in such communities. Now researchers have discovered that bacteria form an unusual solitary wave - a behavior that has never been observed or described before in a living system. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 13, 2009 Category: Biomedical Science Source Type: organizations

Research suggests core nuclear pore elements shared by all eukaryotesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
About 1.7 billion years ago, the cell nucleus burst onto the scene, sequestering the cell’s genetic material inside a protective inner membrane and setting the stage for the evolution of increasingly sophisticated creatures from yeast, say, to plants and human beings. Now research shows that one of the most basic design principles of this new eukaryotic life-form — the gatekeeper to the cell nucleus known as the nuclear pore complex — is largely shared across even the most distantly related eukaryotes. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 9, 2009 Category: Biomedical Science Source Type: organizations

Handle with care: Telomeres resemble DNA fragile sitesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although telomeres are fragile, they don’t have to be handled with care. Researchers at Rockefeller University now show that what keeps our fragile telomeres from falling apart is a protein known as TRF1 that ensures the smooth progression of DNA replication to the end of a chromosome. The work not only shows how telomeres help chromosomes protect their vulnerable ends but also reveals how the genome is made more stable by them. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 9, 2009 Category: Biomedical Science Source Type: organizations

Cells use import machinery to export their goods as wellEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cells use bubbles called vesicles to ferry cargo to and from the membrane. Scientists long believed that this importing and exporting were independent processes. But by imaging individual vesicles as they are fusing with the cell membrane, researchers reveal that these processes have a lot in common: Certain molecules handle cargo moving in both directions. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 2, 2009 Category: Biomedical Science Source Type: organizations

Michael Young receives Gruber Foundation’s 2009 Neuroscience PrizeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Michael W. Young, Richard and Jeanne Fisher Professor and head of the Laboratory of Genetics at Rockefeller University, has received the 2009 Neuroscience Prize of the Peter and Patricia Gruber Foundation for groundbreaking discoveries of the molecular mechanisms that control circadian rhythms in the nervous system. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - July 1, 2009 Category: Biomedical Science Source Type: organizations

Genome-wide map shows precisely where microRNAs do their workEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MicroRNAs are the newest kid on the genetic block. By regulating the unzipping of genetic information, these tiny molecules have set the scientific world alight with their therapeutic potential and wide-ranging applications. But the question remains: How do they work? By using a technique that molecularly cements proteins to RNAs, Rockefeller scientists have decoded a map of microRNA-messenger RNA interactions in the mouse brain, an advance that holds promise for biology and human disease. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - June 17, 2009 Category: Biomedical Science Source Type: organizations

Jeffrey Friedman receives Shaw Prize for discovery of leptinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Jeffrey Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics at Rockefeller, received the 2009 Shaw Prize in Life Science and Medicine. He shares the $1 million award, known as the Nobel Prize of the East, with the Jackson Laboratory's Douglas L. Coleman for their work leading to the discovery of leptin, a hormone that regulates food intake and body weight. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - June 16, 2009 Category: Biomedical Science Source Type: organizations

Research identifies 3D structure of key nuclear pore building blockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research into the molecular machine that filters all information traveling in or out of the cell nucleus contributes to an unfolding picture of cellular evolution that shows a common architecture for the nuclear pore complex (NPC) and the vehicles that transport material between different parts of the cell. Scientists have for the first time glimpsed in three dimensions the subcomplex of the NPC that is its key building block. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - June 7, 2009 Category: Biomedical Science Source Type: organizations

Report identifies early childhood conditions that lead to adult health disparitiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The origins of many adult diseases can be traced to early negative experiences associated with social class and other markers of disadvantage. Confronting the causes of adversity before and shortly after birth may be a promising way to improve adult health and reduce premature deaths, researchers argue in a paper published today in JAMA: The Journal of the American Medical Association. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - June 2, 2009 Category: Biomedical Science Source Type: organizations

Misreading of histone code linked to human cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The development of blood from stem cell to fully formed blood cell follows a genetically determined program. When it doesn’t work properly, genetic mutations can cause the developing cells to turn cancerous. In research published in the journal Nature, Rockefeller University scientists show for the first time that a misreading of blood cells’ histone code is responsible for acute myeloid leukemia, a rare form of the deadly blood cancer. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - June 1, 2009 Category: Biomedical Science Source Type: organizations

Genetic profiling reveals genes active in the earliest brain circuit constructionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Screening for genes that guide the earliest formation of the embryonic brain, researchers identified 229 specifically responsible for subplate neurons, which form the initial scaffolding for assembling cortical circuits. The work indicates the breadth of factors involved in initial neurogenesis and provides investigators with a biochemical handle to start investigating the various contributions. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 29, 2009 Category: Biomedical Science Source Type: organizations

New Rockefeller faculty member studies mechanisms of DNA repairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Agata Smogorzewska, a physician-scientist whose research focuses on DNA repair and on the molecular basis of Fanconi anemia, a genomic instability syndrome that leads to leukemia and other forms of cancer, will join The Rockefeller University as head of the Laboratory of Genome Maintenance. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 27, 2009 Category: Biomedical Science Source Type: organizations

To spread, skin cancer attacks immune dendritic cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
By knocking out or beguiling dendritic cells, some cancer cells can slip the defenses of the immune system and sack the unsuspecting body. Dendritic cells taken from one of the most common types of skin cancer have most of the known genetic and physiologic hallmarks of their able-bodied fellows in healthy skin tissue. But they fail to stimulate an effective immune response. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 26, 2009 Category: Biomedical Science Source Type: organizations

Rockefeller University names Robert Sapolsky 2008 Lewis Thomas Prize winnerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Primatologist and Stanford University neuroscientist Robert M. Sapolsky has been named the recipient of Rockefeller University’s Lewis Thomas Prize for Writing about Science for 2008. The award recognizes Sapolsky’s 2001 publication A Primate’s Memoir: A Neuroscientist’s Unconventional Life Among the Baboons and will be presented to him at a ceremony at the university’s Caspary Auditorium on June 2. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 18, 2009 Category: Biomedical Science Source Type: organizations

For different species, different functions for embryonic microRNAsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Researchers at The Rockefeller University have discovered that a family of microRNAs that regulates early embryonic development is evolutionarily conserved from fish to amphibians and humans, but its function is not. The findings are a warning: Scientists should not assume that what they learn about microRNAs in animal studies will hold true for people. (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 14, 2009 Category: Biomedical Science Source Type: organizations