WFUMB Guidelines/Guidance on Liver Multiparametric Ultrasound. Part 2: Guidance on Liver Fat Quantification
The World Federation for Ultrasound in Medicine and Biology (WFUMB) has promoted the development of this document on multiparametric ultrasound. Part 2 is a guidance on the use of the available tools for the quantification of liver fat content with ultrasound. These are attenuation coefficient, backscatter coefficient, and speed of sound. All of them use the raw data of the ultrasound beam to estimate liver fat content. This guidance has the aim of helping the reader in understanding how they work and interpret the results. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 23, 2024 Category: Radiology Authors: Giovanna Ferraioli, Richard Gary Barr, Annalisa Berzigotti, Ioan Sporea, Vincent Wai ‐Sun Wong, Thomas Reiberger, Thomas Karlas, Maja Thiele, Ana Carolina Cardoso, Oyekoya Taiwo Ayonrinde, Laurent Castera, Christoph Frank Dietrich, Hiroko Iijima, Dong H Tags: Guidelines Source Type: research
Computer-Aided Diagnosis of Duchenne Muscular Dystrophy Based on Texture Pattern Recognition on Ultrasound Images Using Unsupervised Clustering Algorithms and Deep Learning
The feasibility of using deep learning in ultrasound imaging to predict the ambulatory status of patients with Duchenne muscular dystrophy (DMD) was previously explored for the first time. The present study further used clustering algorithms for the texture reconstruction of ultrasound images of DMD data sets and analyzed the difference in echo intensity between disease stages. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 18, 2024 Category: Radiology Authors: Ai-Ho Liao, Chih-Hung Wang, Chong-Yu Wang, Hao-Li Liu, Ho-Chiao Chuang, Wei-Jye Tseng, Wen-Chin Weng, Cheng-Ping Shih, Po-Hsiang Tsui Tags: Original Contribution Source Type: research
In Vitro and In Vivo Behavioral Evaluation of Condensed Lipid-Coated Perfluorocarbon Nanodroplets
Phase-shift contrast agents consist of a liquid perfluorocarbon core that can be vaporized by ultrasound to generate echogenic contrast with excellent spatiotemporal control. The purpose of the present work was to evaluate the in vitro and in vivo behavior of condensed lipid-shelled nanodroplets (NDs) using different analytical procedures. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 17, 2024 Category: Radiology Authors: Romain Melich, Patricia Emmel, Alexis Vivien, Florence Sechaud, Carole Mandaroux, Sofiene Mhedhbi, Philippe Bussat, Isabelle Tardy, Samir Cherkaoui Tags: Original Contribution Source Type: research
Dynamic Contrast-Enhanced Ultrasonography Combined With LR-M Classification Criteria for Differentiating Malignant Liver Nodules at High Risk for Hepatocellular Carcinoma
We aimed to investigate the value of quantitative parameters derived from dynamic contrast-enhanced ultrasonography (DCE-US) and a combination of these quantitative parameters with the LR-M classification criteria in distinguishing hepatocellular carcinoma (HCC) nodules and non-HCC malignancies. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 17, 2024 Category: Radiology Authors: Shibo Qiu, Jianmin Ding, Yandong Wang, Hongyu Zhou, Lin Zhao, Lei Zhao, Yan Zhou, Yaling Fu, Xiang Jing Tags: Original Contribution Source Type: research
Impact of Microbubble Degradation and Flow Velocity on Subharmonic-aided Pressure Estimation (SHAPE): An Experimental Investigation
This study aimed to investigate the impact of microbubble degradation and flow velocity on Sub-Harmonic Aided Pressure Estimation (SHAPE), and to explore the correlation between subharmonic amplitude and pressure as a single factor. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 8, 2024 Category: Radiology Authors: Li Zhang, Yi-fan Dong, Yao Chen, Xiao-gang Li, Ya-hong Wang, Ying Wang, Zhi-tong Ge, Xin Wang, Sheng Cai, Xiao Yang, Qing-li Zhu, Jian-chu Li Tags: Original Contribution Source Type: research
The Utility of a Novel Stacked Microvascular Imaging for Enhanced Detection of Fibrosis in Chronic Liver Diseases
Ultrasonographic imaging plays a primary role to detect fibrotic changes in patients with chronic liver disease (CLD). To enhance detectability of fibrosis in its early stage, we developed a novel stacked microvascular imaging (SMVI) that enables continuous visualization of fibrotic changes in intrahepatic vessels. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 6, 2024 Category: Radiology Authors: Daisuke Miura, Hiromi Suenaga, Kiyoshi Ichihara Tags: Original Contribution Source Type: research
A Preliminary Study on the Application of Contrast-Enhanced Ultrasonography in Children With Peripheral Neuroblastic Tumors
The purpose of this study was to retrospectively analyze the characteristics of contrast-enhanced ultrasound (CEUS) images and quantitative parameters of time-intensity curves (TICs) in children's peripheral neuroblastic tumors (pNTs). By comparing the imaging features and quantitative parameters of the TICs of neuroblastoma (NB) and ganglioneuroblastoma (GNB) patients, we attempted to identify the distinguishing points between NB and GNB. A total of 35 patients confirmed to have pNTs by pathologic examination were included in this study. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 4, 2024 Category: Radiology Authors: Ting Wang, Dan Han, Huan Xiao, Hao Yang, Jing-Yu Chen, Yi Tang Tags: Review Source Type: research
Long-Term Ultrasound Twinkling Detectability and Safety of a Polymethyl Methacrylate Soft Tissue Marker Compared to Conventional Breast Biopsy Markers —A Preclinical Study in a Porcine Model
This study investigates the long-term safety and ultrasound Doppler twinkling detectability of a PMMA breast biopsy marker following local perturbations and different dwell times in a 6-mo animal experiment. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 4, 2024 Category: Radiology Authors: Christine U. Lee, Matthew W. Urban, Gina K. Hesley, Benjamin G. Wood, Thomas R. Meier, Beiyun Chen, Blake A. Kassmeyer, Nicholas B. Larson, A. Lee Miller, James L. Herrick, James W. Jakub, Mara A. Piltin Tags: Original Contribution Source Type: research
Corrigendum to ‘Safety Review of Therapeutic Ultrasound for Spinal Cord Neuromodulation and Blood–Spinal Cord Barrier Opening’ [Ultrasound in Med & Biol. 50 (2024) 317-331]
The authors regret that an error was present in the final row of Table 3 in the column ‘Sonication mode’. ‘4 ms pulse, 100 kHz’ should read ‘4 ms pulse, 100 Hz’. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 4, 2024 Category: Radiology Authors: Rui Xu, Bradley E. Treeby, Eleanor Martin Tags: Corrigendum Source Type: research
Ultrasound-Based Predictive Model to Assess the Risk of Orbital Malignancies
Ultrasound (US) is widely used for evaluating various orbital conditions. However, accurately diagnosing malignant orbital masses using US remains challenging. We aimed to develop an ultrasonic feature-based model to predict the presence of malignant tumors in the orbit. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 3, 2024 Category: Radiology Authors: Yuli Zhang, Youyi Huang, Jie Bi, Haiyan Zhou, Tao Li, Jingqin Fang Tags: Original Contribution Source Type: research
Evaluation of Dual-Frequency Switching HIFU for Optimizing Superficial Ablation
This study proposes a method utilizing dual frequency switching ultrasound (DFSU) to enhance the efficiency and precision of superficial treatments. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - March 27, 2024 Category: Radiology Authors: Wenchang Huang, Yang Jiao, Jiaqi Li, Yan He, Weiwei Shao, Yaoyao Cui Tags: Original Contribution Source Type: research
Commentary on “Neuroinflammation in the Rat Brain After Exposure to Diagnostic Ultrasound” by Lalzad, Wong and Schneider
Lalzad et al. [1] describe a study of the potential for neonatal ultrasound scans (B-mode and Doppler used simultaneously) to induce neuroinflammation using an in vivo mammalian brain model and focus on the immunoreactive cells BA-1 and GFAP as markers of microglia and astrocytes, respectively. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - March 27, 2024 Category: Radiology Authors: Gail ter Haar, Jacques Abramowicz, Brian Fowlkes, Felix Schlachetzki Tags: Letter to the Editor-in-Chief Source Type: research
Synchronized Chemotherapy/Photothermal Therapy/Sonodynamic Therapy of Human Triple-Negative and Estrogen Receptor-Positive Breast Cancer Cells Using a Doxorubicin –Gold Nanoclusters–Albumin Nanobioconjugate
Novel strategies for treating triple-negative breast cancer (TNBC) are ongoing because of the lack of standard-of-care treatment. Nanoframed materials with a protein pillar are considered a valuable tool for designing multigoals of energy-absorbing/medication cargo and are a bridge to cross-conventional treatment strategies. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - March 26, 2024 Category: Radiology Authors: Zahra Kayani, Hossein Heli, Rezvan Dehdari Vais, Hanieh Haghighi, Mohammadreza Ajdari, Naghmeh Sattarahmady Tags: Original Contribution Source Type: research
Determining Ultrasound Parameters for Bursting Polymer Microbubbles for Future Use in Spinal Cord Injury
We believe our poly(lactic acid) (PLA) microbubbles are well suited for therapeutic delivery to spinal cord injury (SCI) using ultrasound-triggered bursting. We investigated the feasibility of clinical ultrasound bursting in situ, the optimal bursting parameters in vitro and the loading and release of a model bio-active DNA. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - March 24, 2024 Category: Radiology Authors: Brian E. Oeffinger, Maria Stanczak, Angelo C. Lepore, John R. Eisenbrey, Margaret A. Wheatley Tags: Original Contribution Source Type: research
Development of an MR-Guided Focused Ultrasound (MRgFUS) Lesioning Approach for the Fornix in the Rat Brain
High-intensity magnetic resonance-guided focused ultrasound (MRgFUS) is a non-invasive therapy to lesion brain tissue, used clinically in patients and pre-clinically in several animal models. Challenges with focused ablation in rodent brains can include skull and near-field heating and accurately targeting small and deep brain structures. We overcame these challenges by creating a novel method consisting of a craniectomy skull preparation, a high-frequency transducer (3 MHz) with a small ultrasound focal spot, a transducer positioning system with an added manual adjustment of ∼0.1 mm targeting accuracy, and MR acoustic r...
Source: Ultrasound in Medicine and Biology - March 24, 2024 Category: Radiology Authors: Carena Cornelssen, Allison Payne, Dennis L. Parker, Matthew Alexander, Robb Merrill, Sharayu Senthilkumar, Jacob Christensen, Karen S. Wilcox, Henrik Od éen, John D. Rolston Tags: Original Contribution Source Type: research
