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The Swedish system for compensation of patient injuries.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Since 1975 Sweden has had a patient insurance system to compensate patients for health-related injuries. The system was initially based on a voluntary patient insurance solution, but in 1997 it was replaced by the Patient Insurance Act. The current Act covers both physical and mental injuries. Although about 9,000-10,000 cases are processed in Sweden annually, compensation is paid in barely half of these cases. In the Swedish patient injury claim processing system, the Patient Claims Panel is the authority that plays an important role in ensuring fair and consistent application of the Act. PMID: 19900150 [...
Source: Upsala Journal of Medical Sciences - November 10, 2009 Category: Journals (General) Authors: Johansson H Tags: Ups J Med Sci Source Type: journals

Maintenance of muscle mass, fiber size, and contractile function in mice lacking the Z-disc protein myotilin.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Background. Myofibrillar myopathies constitute a rare group of congenital neuromuscular disorders, frequently associated with mutations in Z-disc proteins such as myotilin. Myotilin location and interactions with other Z-disc proteins are clearly defined, but its role in the regulation of muscle structure and function remains unknown. The present study aims at investigating this specific role of myotilin. Methods. Skeletal and cardiac muscles were collected from adult mice with a targeted deletion of myotilin (myo(-/-)) and wild-type animals (myo(+/+)). Results and conclusion. Similar skeletal and cardiac musc...
Source: Upsala Journal of Medical Sciences - November 1, 2009 Category: Journals (General) Authors: Ochala J, Carpén O, Larsson L Tags: Ups J Med Sci Source Type: journals

Can low-dose abdominal CT replace abdominal plain film in evaluation of acute abdominal pain?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. NCT was found to be significantly better at providing diagnostic information than APF in patients presenting with acute abdominal pain. It reduced the number of additional radiograms, but the total patient dose remained somewhat higher in the CT group even when using LDCT with 50 mAs. PMID: 19878040 [PubMed - as supplied by publisher] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 1, 2009 Category: Journals (General) Authors: Haller O, Karlsson L, Nyman R Tags: Ups J Med Sci Source Type: journals

Effects of different priming doses of propofol on fentanyl-induced cough during anesthesia induction: A preliminary randomized controlled study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Fentanyl-induced cough is not an uncommon condition during the induction of general anesthesia. A preliminary randomized controlled study was designed to observe the effects of different priming doses of propofol on fentanyl-induced cough during anesthesia induction. A total of 120 patients were randomized into 4 groups (n = 30) to receive the intravenous injection of intralipid (group I), propofol 1 mg.kg(-1) (group II), propofol 1.5 mg.kg(-1) (group III), or propofol 2 mg.kg(-1) (group IV) 1 minute before a bolus of fentanyl 2.5 microg.kg(-1). The occurrence and severity of cough were recorded for 2 minutes ...
Source: Upsala Journal of Medical Sciences - October 12, 2009 Category: Journals (General) Authors: Tang Q, Qian Y, Zhang Q, Yang J, Wang Z Tags: Ups J Med Sci Source Type: journals

Factors for thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Thyroid autoimmunity was associated with female gender, increasing age, long diabetes duration, the persistence of anti-GAD, and with TSH elevation, indicating subclinical hypothyroidism. PMID: 19824863 [PubMed - as supplied by publisher] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - October 12, 2009 Category: Journals (General) Authors: Kakleas K, Paschali E, Kefalas N, Fotinou A, Kanariou M, Karayianni C, Karavanaki K Tags: Ups J Med Sci Source Type: journals

A recruitment breath manoeuvre directly after endotracheal suction improves lung function: An experimental study in pigs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Atelectasis created by endotracheal suction can be opened by inflating the lung for a short duration with low pressure, without over-distension, immediately after suction. PMID: 19736601 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Kasim I, Gulyas M, Almgren B, Hogman M Tags: Ups J Med Sci Source Type: journals

Renoprotective effects of Andrographis paniculata (Burm. f.) Nees in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. The present study reports that the aqueous extract (whole plant) of A. paniculata (Burm. f.) Nees exhibits a significant renoprotective effect in gentamicin-induced nephrotoxicity in male Wistar albino rats. PMID: 19736602 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Singh P, Srivastava MM, Khemani LD Tags: Ups J Med Sci Source Type: journals

Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The increasing incidence of postmenopausal osteoporosis and its related fractures have become global health issues in the recent days. Postmenopausal osteoporosis is the most frequent metabolic bone disease; it is characterized by a rapid loss of mineralized bone tissue. Hormone replacement therapy has proven efficacious in preventing bone loss but not desirable to many women due to its side-effects. Therefore we are in need to search the natural compounds for a treatment of postmenopausal symptoms in women with no toxic effects. In the present study, we have evaluated the effect of petroleum-ether extract of Cissus qu...
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Potu BK, Rao MS, Nampurath GK, Chamallamudi MR, Prasad K, Nayak SR, Dharmavarapu PK, Kedage V, Bhat KM Tags: Ups J Med Sci Source Type: journals

Comparison of two visual angiographic perfusion grades in acute myocardial infarction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Our findings suggest that the clearance of the dye (described by TMP) is more characteristic to myocardial recovery after AMI, than maximal contrast density (described by MBG) in the clinical practice. PMID: 19736604 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Ungi T, Sasi V, Ungi I, Forster T, Palko A, Nemes A Tags: Ups J Med Sci Source Type: journals

Glomerular filtration rate estimation using the Cockcroft-Gault and Modification of Diet in Renal Disease formulas for digoxin dose adjustment in patients with heart failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. For GFR lower than 60 mL/min, the high interindividual variation of the digoxin total CL found among patients with similar renal function is an important limiting factor in the prediction of digoxin dosage regimens. PMID: 19736605 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Vazquez-Hernandez M, Bouzas L, Tutor JC Tags: Ups J Med Sci Source Type: journals

Serum vitamin B12 and folate status among patients with chemotherapy treatment for advanced colorectal cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Patients with ACRC seem to have fairly adequate cobalamin and folate status before and during chemotherapy treatment. This study indicates that ACRC patients receiving chemotherapy do not need supplementation with vitamin B12 and folate. A minor portion of the patients had folate deficiency, and most of those patients had severe toxicity. Patients with subclinically low cobalamin values had surprisingly better survival. PMID: 19736606 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Bystrom P, Bjorkegren K, Larsson A, Johansson L, Berglund A Tags: Ups J Med Sci Source Type: journals

Lower leptin levels in young non-obese male smokers than non-smokers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since the effect of smoking on plasma leptin has been divergent in clinical trials, which might have occurred due to selection of heterogeneous study populations, we investigated whether there is such an association in a group of healthy, non-obese, young male adults. A total of 54 smokers (mean age: 21.18+/-1.62; body mass index (BMI): 19.60+/-0.85) and 26 non-smokers (mean age 21.69+/-3.0; BMI: 21.59+/-1.39) with similar daily physical activities and diet and without any documented disease were enrolled, and their plasma leptin levels were determined for the comparison between the two groups. The mean BMI and plasma ...
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Koc B, Bulucu F, Karadurmus N, Sahin M Tags: Ups J Med Sci Source Type: journals

Prevalence of depression, its correlates among students, and its effect on health-related quality of life in a Turkish university.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions.The prevalence of depression among the university students in this region of Turkey was wide-spread, affecting negatively the HRQoL of the students. For prevention and control of depression, depression information and knowledge need to be addressed by health education programs. PMID: 19736608 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Arslan G, Ayranci U, Unsal A, Arslantas D Tags: Ups J Med Sci Source Type: journals

Calcific myonecrosis and the role of imaging in the diagnosis: A case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report magnetic resonance imaging (MRI) and CT imaging features of calcific myonecrosis arising 43 years after trauma. A 62-year-old man presented with a slowly enlarging mass in the left lower leg. Plain radiographs revealed a soft tissue mass with extensive amorphous calcification. The middle third of the tibia and fibula were eroded. MRI demonstrated peripheral ring enhancement on postcontrast fat-suppressed T1-weighted images. Volume-rendered images extracting only the images of bone and vessels also showed many branches from the tibialis posterior and peroneal arteries around the bone defect. During the operation, ...
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Okada A, Hatori M, Hosaka M, Watanuki M, Itoi E Tags: Ups J Med Sci Source Type: journals

Tenosynovitis with rice body formation in a non-tuberculosis patient: A case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we present a 68-year-old man with rice body formation in the flexor tendon sheath of the fingers without any inflammatory diseases such as tuberculosis or rheumatoid arthritis. The patient visited our institute in March 2004 with a one-month history of swelling and pain of the right distal forearm. Laboratory data were within normal limits, and the rheumatoid factor was negative. He had no history of tuberculosis, and the tuberculin reaction was weakly positive. Magnetic resonance (MR) images showed a mass measuring 6 cmx4 cm around the flexor tendons of the forearm. Many rice bodies had been erupted from a...
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Nagasawa H, Okada K, Senma S, Chida S, Shimada Y Tags: Ups J Med Sci Source Type: journals

Spontaneous rupture of the extensor pollicis brevis tendon in a baseball pitcher: A case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 15-year-old pitcher on a boys' Little League baseball team suffered spontaneous rupture of the extensor pollicis brevis (EPB) tendon. Since the EPB tendon was, at surgery, found hypoplastic and non-functional, transfer of the extensor indicis proprius (EIP) tendon was carried out. After a 6-month period of rehabilitation and follow-up, the patient was able to resume playing baseball. Although rupture of the EPB is rare, transfer of the EIP tendon is one of the treatments of choice for such injuries. PMID: 19736611 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - September 9, 2009 Category: Journals (General) Authors: Fujimoto T, Tanase Y, Oribe T, Watanabe Y Tags: Ups J Med Sci Source Type: journals

Immunohistochemical localization of phosphohistidine phosphatase PHPT1 in mouse and human tissues.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Protein histidine phosphorylation accounts for about 6% of the total protein phosphorylation in eukaryotic cells; still details concerning histidine phosphorylation and dephosphorylation are limited. A mammalian 14-kDa phosphohistidine phosphatase, also denominated PHPT1, was found 6 years ago that provided a new tool in the study of phosphohistidine phosphorylation. The localization of PHPT1 mRNA by Northern blot analysis revealed high expression in heart and skeletal muscle. The main object of the present study was to determine the PHPT1 expression on protein level in mouse tissues in order to get further information...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Zhang XQ, Sundh UB, Jansson L, Zetterqvist O, Ek P Tags: Ups J Med Sci Source Type: journals

Alteration of chondroitin sulfate composition on proteoglycan produced by knock-in mouse embryonic fibroblasts whose versican lacks the A subdomain.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Versican/proteoglycan-mesenchymal (PG-M) is a large chondroitin sulfate (CS) proteoglycan of the extracellular matrix (ECM) that is constitutively expressed in adult tissues such as dermis and blood vessels. It serves as a structural macromolecule of the ECM, while in embryonic tissue it is transiently expressed at high levels and regulates cell adhesion, migration, proliferation, and differentiation. Knock-in mouse embryonic (Cspg2(Delta3/Delta3)) fibroblasts whose versican lack the A subdomain of the G1 domain exhibit low proliferation rates and acquire senescence. It was suspected that chondroitin sulfate on versica...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Suwan K, Hatano S, Kongtawelert P, Pothacharoen P, Watanabe H Tags: Ups J Med Sci Source Type: journals

Patterns of language and auditory dysfunction in 6-year-old children with epilepsy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In a previous study we reported difficulty with expressive language and visuoperceptual ability in preschool children with epilepsy and otherwise normal development. The present study analysed speech and language dysfunction for each individual in relation to epilepsy variables, ear preference, and intelligence in these children and described their auditory function. Twenty 6-year-old children with epilepsy (14 females, 6 males; mean age 6:5 y, range 6 y-6 y 11 mo) and 30 reference children without epilepsy (18 females, 12 males; mean age 6:5 y, range 6 y-6 y 11 mo) were assessed for language and auditory ability. Low ...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Selassie GR, Olsson I, Jennische M Tags: Ups J Med Sci Source Type: journals

Supratrochlear foramen of the humerus: an anatomico-radiological study with clinical implications.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The results of our study show that STF is more common on the right side, with the oval shape being more common. The respective sides did not exhibit any statistical significant differences. Presence of STF may be important for anthropological, clinical, and academic purpose. PMID: 19396695 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Nayak SR, Das S, Krishnamurthy A, Prabhu LV, Potu BK Tags: Ups J Med Sci Source Type: journals

Effects of tendon transfer to restore index finger abduction for severe cubital tunnel syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The extensor pollicis brevis tendon transfer is simple and useful to restore index finger abduction and pinch strength for severe cubital tunnel syndrome. PMID: 19396696 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Nobuta S, Sato K, Kanazawa K, Hatori M, Itoi E Tags: Ups J Med Sci Source Type: journals

Smoking as a product of gene-environment interaction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of the present study was to investigate the interaction between a variation in the 5-HTTLPR and family environment in relation to smoking habits, nicotine dependence, and nicotine and cotinine levels in hair samples. A random Swedish adolescent population sample (n = 785), from which 200 individuals were stratified regarding behaviour, was genotyped for 5-HTTLPR and assessed with semi-structured interviews, a questionnaire, and hair analyses of nicotine and cotinine. The 5-HTTLPR gene interacted with a poor family environment to predict smoking habits, as well as nicotine and cotinine levels. The risk of bein...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Nilsson KW, Oreland L, Kronstrand R, Leppert J Tags: Ups J Med Sci Source Type: journals

Thrombospondin 1 expression and angiogenesis in breast carcinoma and their relation with platelet activity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigates angiogenesis and the expression of thrombospondin 1 in invasive ductal carcinoma of the breast and their possible relation to platelet counts and platelet activity. The study included 20 cases of invasive ductal carcinoma. Platelet activity was evaluated by determining thromboxane B2 and cyclic guanosine monophosphate (cGMP) levels by enzyme immunoassay (EIA).Thrombospondin (TSP) 1 and CD34 expression was studied immunohistochemically. Mean platelet count of the patient group was significantly greater than the mean platelet count of the control group (P < 0.05). The platelet counts were positivel...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Tokyol C, Ersoz G, Dilek FH, Gencer E, Kosar MN, Dilek ON Tags: Ups J Med Sci Source Type: journals

Elevated levels of thymidine kinase 1 peptide in serum from patients with breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: This study indicates that the tumour proliferation marker TK has a potential as a serum marker in breast cancer. Further studies are warranted to verify this observation. PMID: 19396699 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Carlsson L, Larsson A, Lindman H Tags: Ups J Med Sci Source Type: journals

Langerhans cell histiocytosis of the sternum.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of Langerhans cell histiocytosis involving the sternum. The patient was a 12-year-old girl presenting with anterior chest pain and swelling. Radiographs and computed tomography showed an osteolytic lesion in the sternum. Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia. Incisional biopsy for the sternum lesion was performed, and the histopathologic diagnosis was Langerhans cell histiocytosis. She was treated with chemotherapy and the symptoms disappeared. PMID: 19396700 [PubMed - in process] (Source: Upsal...
Source: Upsala Journal of Medical Sciences - June 27, 2009 Category: Journals (General) Authors: Tsuchie H, Okada K, Nagasawa H, Yano M, Nanjyo H, Shimada Y Tags: Ups J Med Sci Source Type: journals

Uppsala University Hospital 300 years--a survey of the surgical development.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Professor Lars Roberg, the initiator of the Nosocomium Academicum (1708), our first university hospital in Sweden, claimed that 'no-one who does not understand surgery is a completely trained doctor'. However, it was not until the end of 19th century that modern surgery was born. The Academic Hospital was opened in 1867, and at the turn of that century Uppsala had a flourishing period under the influence of Karl Gustav Lennander, professor of surgery. In 1889 he performed the first appendectomy in Scandinavia. At the end of the 19th century the surgical tree began to branch out. In Uppsala gynaecology and obstetrics wa...
Source: Upsala Journal of Medical Sciences - March 5, 2009 Category: Journals (General) Authors: Johansson H Tags: Ups J Med Sci Source Type: journals

Muscle biopsies in children--an evaluation of histopathology and clinical value during a 5-year period.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents the experience with paediatric muscle biopsies during a 5-year period at a routine pathology laboratory. A total number of 58 cases were included, and indications, microscopical findings, and final histopathological diagnoses were recorded. A total of 21 biopsies were from females (36%) and 37 biopsies from males (64%); 53% of the cases were from children under 2 years of age. Major pathological findings were found in 30% comprising muscular dystrophy, neurogenic atrophy, and congenital and metabolic disorders, even in cases with vague clinical manifestations. These findings confirm the high diagnostic...
Source: Upsala Journal of Medical Sciences - March 5, 2009 Category: Journals (General) Authors: Skram MK, Gulati S, Larsson E, Lindal S, Torp SH Tags: Ups J Med Sci Source Type: journals

Determination of blood sirolimus concentrations in liver and kidney transplant recipients using the Innofluor fluorescence polarization immunoassay: comparison with the microparticle enzyme immunoassay and high-performance liquid chromatography-ultraviolet method.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The Innofluor FPIA is a valid alternative with an analogous performance to the MEIA for the therapeutic monitoring of sirolimus. PMID: 19242874 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 5, 2009 Category: Journals (General) Authors: Bouzas L, Hermida J, Tutor JC Tags: Ups J Med Sci Source Type: journals

A further move into electronic publishing.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19242866 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Andersson A, Ronquist G, Karlsson T Tags: Ups J Med Sci Source Type: journals

Uppsala University Hospital 300 years-a survey of the surgical development.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Professor Lars Roberg, the initiator of the Nosocomium Academicum (1708), our first university hospital in Sweden, claimed that 'no-one who does not understand surgery is a completely trained doctor'. However, it was not until the end of 19th century that modern surgery was born. The Academic Hospital was opened in 1867, and at the turn of that century Uppsala had a flourishing period under the influence of Karl Gustav Lennander, professor of surgery. In 1889 he performed the first appendectomy in Scandinavia. At the end of the 19th century the surgical tree began to branch out. In Uppsala gynaecology and obstetrics wa...
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Johansson H Tags: Ups J Med Sci Source Type: journals

Metabolic stress-like condition can be induced by prolonged strenuous exercise in athletes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Few studies have examined energy metabolism during prolonged, strenuous exercise. We wanted therefore to investigate energy metabolic consequences of a prolonged period of continuous strenuous work with very high energy expenditure. Twelve endurance-trained athletes (6 males and 6 females) were recruited. They performed a 7-h bike race on high work-load intensity. Physiological, biochemical, endocrinological, and anthropometric muscular compartment variables were monitored before, during, and after the race. The energy expenditure was high, being 5557 kcal. Work-load intensity (% of VO(2) peak) was higher in females (7...
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Branth S, Hambraeus L, Piehl-Aulin K, Essen-Gustavsson B, Akerfeldt T, Olsson R, Stridsberg M, Ronquist G Tags: Ups J Med Sci Source Type: journals

BAL fluid cells in newly diagnosed pulmonary sarcoidosis with different clinical activity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Independently of clinical symptoms at the time of diagnosis sarcoid patients have significantly different BAL fluid cell patterns compared to healthy persons. BAL fluid cell changes are more prominent in corticosteroid non-treated patients with clinically active sarcoidosis. Treatment with systemic corticosteroids may modify typical BALF cellular patterns of sarcoidosis. PMID: 19242869 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Danila E, Jurgauskiene L, Norkuniene J, Malickaite R Tags: Ups J Med Sci Source Type: journals

Time-trend of melanoma screening practice by primary care physicians: A meta-regression analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Considering the increasing incidence of melanoma and other skin malignancies, as well as their relative potential consequences, the FBSE implementation time-trend we retrieved should be considered a worrisome phenomenon. PMID: 19242870 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Valachis A, Mauri D, Karampoiki V, Polyzos NP, Cortinovis I, Koukourakis G, Zacharias G, Xilomenos A, Tsappi M, Casazza G Tags: Ups J Med Sci Source Type: journals

Muscle biopsies in children-an evaluation of histopathology and clinical value during a 5-year period.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report presents the experience with paediatric muscle biopsies during a 5-year period at a routine pathology laboratory. A total number of 58 cases were included, and indications, microscopical findings, and final histopathological diagnoses were recorded. A total of 21 biopsies were from females (36%) and 37 biopsies from males (64%); 53% of the cases were from children under 2 years of age. Major pathological findings were found in 30% comprising muscular dystrophy, neurogenic atrophy, and congenital and metabolic disorders, even in cases with vague clinical manifestations. These findings confirm the high diagnostic...
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Skram MK, Gulati S, Larsson E, Lindal S, Torp SH Tags: Ups J Med Sci Source Type: journals

Imaging features of foreign body granuloma in the lower extremities mimicking a soft tissue neoplasm.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report three patients of foreign body granulomas in the lower extremities with emphasis placed on their unique clinical and radiological features. The involved sites were the foot, posterior thigh, and posterior lower leg, with wooden splinters in two patients and a fragment of tile in one. Plain radiographs could not reveal the existence of foreign bodies. Magnetic resonance imaging (MRI) showed foreign bodies as low intensities on both T1- and T2-weighted images in two patients, and the surrounding reactive lesion as low to iso intensities on T1- and high intensities on T2-weighted images in all the patients. The peri...
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Ando A, Hatori M, Hagiwara Y, Isefuku S, Itoi E Tags: Ups J Med Sci Source Type: journals

Surgical treatment of depression fractures of the lateral tibial plateau using porous titanium granules.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The clinical and radiological results were excellent in this pilot study of four cases of depression fracture of the lateral tibial plateau, where, in addition to internal fixation with screws or a buttress plate, porous titanium granules were used to support the elevated articular surface. PMID: 19242873 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Jonsson B, Mjoberg B Tags: Ups J Med Sci Source Type: journals

Determination of blood sirolimus concentrations in liver and kidney transplant recipients using the Innofluor(R) fluorescence polarization immunoassay: Comparison with the microparticle enzyme immunoassay and high-performance liquid chromatography-ultraviolet method.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. The Innofluor(R) FPIA is a valid alternative with an analogous performance to the MEIA for the therapeutic monitoring of sirolimus. PMID: 19242874 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Bouzas L, Hermida J, Tutor JC Tags: Ups J Med Sci Source Type: journals

Nocardiosis in a renal transplant recipient following rituximab preconditioning.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19242875 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - March 1, 2009 Category: Journals (General) Authors: Flohr TR, Sifri CD, Brayman KL, Hagspiel KD, Sawyer RG, Pruett TL, Bonatti HJ Tags: Ups J Med Sci Source Type: journals

Pregnancy-associated myocardial infarction: a report of two cases and review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Myocardial infarction, and particularly spontaneous coronary artery dissection, should be in the differential diagnosis of pregnant women presenting with cardiac-type symptoms, despite perceived lack of risk factors. Angiography will aid in diagnosis, and multiple therapeutic modalities exist. PMID: 18991245 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 13, 2008 Category: Journals (General) Authors: Shahabi S, Smith NA, Chanana C, Abbott JD, Copel J, Setaro JF Tags: Ups J Med Sci Source Type: journals

Methods in neuroendocrine histopathology, a methodological overview.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Light microscopy is still the main tool in diagnostic histopathology, though it does not always lead to a definitive diagnosis. It has therefore been a constant ambition to develop methods which can add further information to the diagnosis. In endocrine pathology, a major problem has been to distinguish between neuroendocrine and non-neuroendocrine tumours. The silver stains, such as the Bodian, Grimelius and Sevier-Munger methods, were the first useful "general neuroendocrine" markers. Electron microscopy can also be useful for identifying neuroendocrine tumours. A further step forward was the introduction of histoche...
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Grimelius L Tags: Ups J Med Sci Source Type: journals

Viscosupplementation with Hyaluronic Acid in Hip Osteoarthritis (a review).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Despite the initial promising results, some questions still remain open : 1) the characteristics of responders must be more precisely defined; 2) the treatment schedules, at present mainly based on the individual clinical experience, need a proper and accepted standardization. Finally, larger and placebo controlled trials are necessary to confirm the efficacy of VS in hip OA. PMID: 18991239 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Abate M, Pelotti P, De Amicis D, Di Iorio A, Galletti S, Salini V Tags: Ups J Med Sci Source Type: journals

Factors influencing the prevalence of pulmonary nodules in lung cancer screening trials: re-evaluation of a CT study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Numerous false positive findings are a problem in computed tomography based lung cancer screening trials. The potential patient-related variables that could predict the existence of such lung nodules were studied. 526 construction workers (age 38 - 81 yrs.) previously screened with spiral computed tomography were evaluated. Background features (age, body mass index, stature, sex, C-reactive protein, erythrocyte sedimentation rate, asbestos exposure and smoking history), reported symptoms (general condition, cough, mucous production, dyspnoea, chest pain) and findings in high resolution CT were related to the existence ...
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Vehmas T Tags: Ups J Med Sci Source Type: journals

Delays in the diagnosis and treatment of primary lung cancer: are longer delays associated with advanced pathological stage?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We aimed to investigate the delays from the first symptom to thoracotomy and to examine whether the delays cause the stage advancement in lung cancer. This prospective study included 138 patients with non-small cell lung carcinoma who underwent thoracotomy. Clinical files of the patients were analyzed and a questionnaire was created to obtain information from the patients. The mean duration values were 81.3 days for the application interval, 61.3 days for the referral interval, 20.3 days for the diagnostic interval, and 21.9 days for the treatment interval. The application interval was longer than 30 days (patient dela...
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Yilmaz A, Damadoglu E, Salturk C, Okur E, Yagci Tuncer L, Halezeroglu S Tags: Ups J Med Sci Source Type: journals

Over-expression of Decoy Receptor 3 in Gastric Precancerous Lesions and Carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: DcR3 is over-expressed in human GC and positively correlated with development and metastases of gastric lesions. The DcR3 gene might serve as an important molecular biological indicator in diagnosing and predicating the clinical outcome in GC patients. PMID: 18991242 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Chen G, Luo D Tags: Ups J Med Sci Source Type: journals

Swedish sperm donors are driven by altruism, but shortage of sperm donors leads to reproductive travelling.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Identifiable sperm donors are driven by altruistic motives, but shortage of sperm donors leads to reproductive travelling. Recruitment strategies to increase the number of sperm donors in Sweden are therefore warranted. PMID: 18991243 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Ekerhovd E, Faurskov A Tags: Ups J Med Sci Source Type: journals

Biochemical effects of consumption of eggs containing omega-3 polyunsaturated fatty acids.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Today, eggs with an increased content of -3 fatty acids are available but there are few publications on the effects of consumption of such eggs on the lipoproteins and acute phase markers in humans. The aim of the present study was to evaluate the effects of consump-tion of standard eggs and -3 enriched eggs on lipoproteins, glucose and inflammation markers. Nineteen healthy volunteers consumed one extra egg per day of either standard eggs or omega-3 enriched eggs in a double-blind, cross-over study. The duration of each period was 1 month. The effects of the different egg diets on apolipoprotein A1 and B (Apo A1 and B...
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Ohman M, Akerfeldt T, Nilsson I, Rosen C, Hansson LO, Carlsson M, Larsson A Tags: Ups J Med Sci Source Type: journals

Pregnancy- associated myocardial infarction:A report of two cases and review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Myocardial infarction, and particularly spontaneous coronary artery dissection, should be in the differential diagnosis of pregnant women presenting with cardiac-type symptoms, despite perceived lack of risk factors. Angiography will aid in diagnosis, and multiple therapeutic modalities exist. PMID: 18991245 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - November 12, 2008 Category: Journals (General) Authors: Shahabi S, Smith NA, Chanana C, Abbott JD, Copel J, Setaro JF Tags: Ups J Med Sci Source Type: journals

Pulmonary nocardiosis with brain abscess in a sensitized kidney transplant recipient with a history of repeated graft loss and HLA-antibody depletion treatment--a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nocardiosis is an opportunistic infection with unfavourable prognosis and is predominantly seen in immunocompromised patients. We here present a kidney transplant recipient with a history of two early graft losses who subsequently developed Human Leukocyte Antigen (HLA)-antibodies and underwent a desensitization treatment with plasmapheresis and monoclonal anti-CD20 antibody application. However, 3 months after a third HLA-identical kidney transplantation he developed Nocardiosis with pulmonary and asymptomatic brain manifestation. The present case report exemplifies this opportunistic infection and gives an overview o...
Source: Upsala Journal of Medical Sciences - June 5, 2008 Category: Journals (General) Authors: Biglarnia AR, Wadström J, Tufveson G, Eriksson BM Tags: Ups J Med Sci Source Type: journals

Identifying candidate genes involved in brain tumor formation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Malignant primary brain tumors, gliomas, often overexpress both platelet-derived growth factor (PDGF) ligands and receptors providing an autocrine and/or paracrine boost to tumor growth. Glioblastoma multiforme (GBM) is the most frequent glioma. Its aggressive and infiltrative growth renders it extremely difficult to treat. Median survival after diagnosis is currently only 12-14 months. The present review describes the use of retroviral tagging to identify candidate cancer-causing genes that cooperate with PDGF in brain tumor formation. Newborn mice injected intracerebrally with a Moloney murine leukemia retrovirus car...
Source: Upsala Journal of Medical Sciences - June 4, 2008 Category: Journals (General) Authors: Johansson Swartling F Tags: Ups J Med Sci Source Type: journals

In Vitro Investigation of the Antibacterial Effect of Ketamine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Ketamine with higher doses showed antibacterial activity. We thought that it will be proper to use ketamine hesitantly in experimental animal studies like sepsis and translocation. PMID: 18521797 [PubMed - as supplied by publisher] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - June 4, 2008 Category: Journals (General) Authors: Gocmen S, Buyukkocak U, Caglayan O Tags: Ups J Med Sci Source Type: journals