Vascular Medicine recent issues
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Endograft limb collapse
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Roche-Nagle, G. M, Barry, M. C Tags: Articles Source Type: journals
Herpes vasculitis in systemic lupus erythematosus
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Chi, Y.-W., Osinbowale, O. Tags: Articles Source Type: journals
Disparity in outcomes of surgical revascularization for limb salvage. Race and gender are synergistic determinants of vein graft failure and limb loss. Nguyen LL, Hevelone N, Rogers SO, Bandyk DF, Clowes AW, Moneta GL, Lipsitz S, Conte MS. Circulation. 2009; 119: 123-130.
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ConclusionsNo differences were observed in mortality or primary patency at 30 days or at 1 year among individual and combined race/gender groups. Black patients, especially black women, were found to have worse secondary patency and limb salvage outcomes after vein bypass surgery for CLI. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Kreatsoulas, C., Anand, S. S Tags: Articles Source Type: journals
SVM - May 2009 Presidential Address
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Bacharach, J M. Tags: Articles Source Type: journals
Novel markers of peripheral arterial disease
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AbstractPeripheral arterial disease (PAD), a relatively common manifestation of atherosclerotic vascular disease, is associated with significant morbidity and mortality. Although conventional risk factors contribute to the onset and progression of PAD, the role of ‘novel’ biomarkers in pathways of inflammation, thrombosis, lipoprotein metabolism, and oxidative stress in determining susceptibility to PAD is being increasingly recognized. Validation of novel risk factors for PAD may allow earlier detection, an improved understanding of disease etiology and progression, and the development of new therapies. In thi...
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Khawaja, F. J, Kullo, I. J Tags: Articles Source Type: journals
An unusual etiology of a subclavian artery aneurysm
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In conclusion, an EH is a rare vascular tumor. The presence of vascular hyperplasia with plump endothelial cells protruding into the lumen is the most important discriminator in establishing the diagnosis of EH. Vascular neoplasms presenting as aneurysms should be considered, especially if other etiologies can be excluded. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Selvaraj, A. D., Stephen, E., Keshava, S. N., Agarwal, S., Shah, S. Tags: Articles Source Type: journals
Ischemic steal syndrome following arm arteriovenous fistula for hemodialysis
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We describe the percutaneous treatments and surgical revisions that attempt to restore flow to the hand without compromising the fistula. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Zamani, P., Kaufman, J., Kinlay, S. Tags: Articles Source Type: journals
Percutaneous revascularization of occluded renal arteries in the setting of acute renal failure
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We report the case of a 60-year-old patient with acute renal failure and occluded bilateral renal arteries presenting with acute pulmonary edema and non-ST segment elevation myocardial infarction. The patient required renal replacement therapy with hemodialysis and was subsequently successfully treated with bilateral renal artery stent placement. Marked improvement in renal function was noted within 1 week with freedom from the need for renal replacement therapy at 4 months of follow-up. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Islam, M A., Rosenfield, K., Maree, A. O, Patel, P. M, Jaff, M. R Tags: Articles Source Type: journals
Sirolimus-eluting stent placement for refractory renal artery in-stent restenosis: sustained patency and clinical benefit at 24 months
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We report a case of sustained 24-month patency after repair of recurrent renal artery in-stent restenosis with use of a sirolimus-eluting stent. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Lookstein, R. A, Talenfeld, A. D, Raju, R., Vorchheimer, D. A, Olin, J. W, Marin, M. L Tags: Articles Source Type: journals
Brachial artery diameter, blood flow and flow-mediated dilation in sleep-disordered breathing
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In conclusion, this study supports a moderate association of SDB and larger baseline brachial artery diameter, which may reflect SDB-induced vascular remodeling. This study does not support a link between SDB and endothelial dysfunction as measured by brachial artery flow-mediated dilation. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Chami, H. A, Keyes, M. J, Vita, J. A, Mitchell, G. F, Larson, M. G, Fan, S., Vasan, R. S, O'Connor, G. T, Benjamin, E. J, Gottlieb, D. J Tags: Articles Source Type: journals
Risk factors and underlying mechanisms for venous stasis syndrome: a population-based case-control study
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In conclusion, increasing patient age and BMI, prior DVT (particularly left leg DVT), longer time interval since DVT and varicose veins are independent risk factors for venous stasis syndrome. Venous stasis syndrome related to DVT is due to venous outflow obstruction and venous valvular incompetence, while venous stasis syndrome related to older age and to varicose veins is due to venous outflow obstruction and to venous valvular incompetence, respectively. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Ashrani, A. A, Silverstein, M. D, Lahr, B. D, Petterson, T. M, Bailey, K. R, Melton, L J., Heit, J. A Tags: Articles Source Type: journals
A normal penile pressure cannot rule out the presence of lesions on the arteries supplying the hypogastric circulation in patients with arterial claudication
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In conclusion, the penile brachial index is relatively insensitive for the detection of proximal abnormal blood flow impairment except in the case of bilateral occlusion of arteries supplying the hypogastric circulation in patients with claudication. A normal penile pressure is probably not efficient enough to rule out the presence of lesions on the arteries towards the hypogastric circulation in patients with arterial claudication. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Mahe, G., Leftheriotis, G., Picquet, J., Jaquinandi, V., Saumet, J. L., Abraham, P. Tags: Articles Source Type: journals
Relationship of heavy drinking, lipoprotein (a) and lipid profile to infrarenal aortic diameter
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In conclusion, there was a positive association between infrarenal aortic diameters and heavy drinking, as well as lipoprotein (a) levels. Furthermore, the novel and unexpected inverse association between LDL-C/HDL-C, LDL-C, TC/HDL-C and abdominal aortic diameter may suggest a possible role for anti-atherogenic lipid profile (characterized by a higher level of HDL-C and lower level of LDL-C) in aortic dilatation processes, which need to be clarified by further studies. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Wang, J.-a., Chen, X.-f., Yu, W.-f., Chen, H., Lin, X.-f., Xiang, M.-j., Fang, C.-f., Du, Y.-x., Wang, B. Tags: Articles Source Type: journals
Design of the multicenter standardized supervised exercise training intervention for the 'CLaudication: Exercise Vs Endoluminal Revascularization (CLEVER) study'
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In conclusion, a multicenter approach to disseminate the supervised exercise training technique and to evaluate its efficacy, safety and cost-effectiveness for patients with claudication due to peripheral arterial disease (PAD) is being evaluated for the first time in CLEVER. The CLEVER study will further establish the role of supervised exercise training in the treatment of claudication resulting from PAD and provide standardized methods for use of supervised exercise training in future PAD clinical trials as well as in clinical practice. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Bronas, U. G, Hirsch, A. T, Murphy, T., Badenhop, D., Collins, T. C, Ehrman, J. K, Ershow, A. G, Lewis, B., Treat-Jacobson, D. J, Walsh, M E., Oldenburg, N., Regensteiner, J. G Tags: Articles Source Type: journals
High-resolution 3D contrast-enhanced MRA with parallel imaging techniques before endovascular interventional treatment of arterial stenosis
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This study aimed to evaluate the efficacy of high-resolution 3D contrast-enhanced magnetic resonance angiography (3D CE MRA) with parallel imaging techniques for the diagnosis of various arterial stenoses and its value for planning endovascular interventional treatment. Thirty-five patients underwent 3D CE MRA before endovascular interventional treatment. Numbers of patients were as follows: clinically documented renal artery stenosis (n = 10), renal transplant artery stenosis (n = 1), carotid artery stenosis (n = 12), iliac artery stenosis (n = 11) and femoro-popliteal artery stenos...
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Lin, J., Li, D., Yan, F. Tags: Articles Source Type: journals
Lower-leg symptoms in peripheral arterial disease are associated with anxiety, depression, and anhedonia
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In conclusion, PAD patients with atypical leg symptoms or pain at rest reported more impaired mood than patients without those symptoms. These patients should be monitored closely in clinical practice, as previous research in cardiovascular patients has shown that mood disorders and sub-threshold symptoms predict poor prognosis. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Smolderen, K. G, Hoeks, S. E, Pedersen, S. S, van Domburg, R. T, de Liefde, I. I, Poldermans, D. Tags: Articles Source Type: journals
An unequal social distribution of peripheral arterial disease and the possible explanations: results from a population-based study
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In conclusion, our study demonstrates that PAD is more pronounced in men and women with lower socioeconomic status. Diabetes prevention and smoking prevention and cessation programs need to specifically target individuals of lower income and education. According to our findings, prevention of PAD would benefit extraordinarily. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 6, 2009 Category: Internal Medicine Authors: Kroger, K., Dragano, N., Stang, A., Moebus, S., Mohlenkamp, S., Mann, K., Siegrist, J., Jockel, K.-H., Erbel, R., on behalf of the Heinz Nixdorf Recall Study Investigator Group Tags: Articles Source Type: journals
A chronic compression of the upper mediastinal veins by a retrosternal goiter
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Szuba, A., Poreba, R., Podgorski, F., Andrzejak, R. Tags: Article Source Type: journals
Popliteal venous aneurysm
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Attaya, H., Gloviczki, P., McBane, R. D Tags: Article Source Type: journals
In support of AHA indications for screening angiography at the time of coronary arteriography: understanding the recommendations and clarifying the goals
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Rundback, J. H Tags: Article Source Type: journals
Screening renal angiography as a routine part of cardiac catheterization: a reappraisal
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Slovut, D. P Tags: Article Source Type: journals
Rotational vertebrobasilar ischemia due to vertebral artery dynamic stenoses complicated by an ostial atherosclerotic stenosis
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We describe a patient with rotational vertebrobasilar ischemia (RVBI) due to vertebral artery (VA) compressive stenoses during neck rotation, complicated by an ostial atherosclerotic stenosis (OAS). Referred for ‘near-syncopal spells’, inquiry revealed a symptom-complex consistent with vertebrobasilar transient ischemic attacks (TIAs) provoked by head rotation. VA dynamic angiography with imaging via prevertebral subclavian injections in neck-rotated positions while reproducing symptoms, demonstrated two compressive stenoses not present in the neck-neutral position, establishing the diagnosis of RVBI due to CT-...
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Natello, G. W, Carroll, C. M, Katwal, A. B Tags: Article Source Type: journals
Percutaneous revascularization of persistent renal artery in-stent restenosis
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We describe a case in a patient who initially presented with renal insufficiency and multi-drug hypertension in the setting of severe bilateral renal artery stenosis. Her renal artery stenosis was initially successfully treated by percutaneous deployment of bilateral bare metal renal artery stents. After initial improvement of her hypertension and renal insufficiency, both parameters declined and follow-up duplex evaluation confirmed renal artery in-stent restenosis. Owing to other medical co-morbidities she was felt to be a poor surgical candidate and was subsequently treated first with bilateral cutting balloon angioplas...
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Patel, P. M, Eisenberg, J., Islam, M A., Maree, A. O, Rosenfield, K. A Tags: Article Source Type: journals
Hypercholesterolemia impairs exercise capacity in mice
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In conclusion, aerobic exercise dysfunction is observed in murine models of genetic and diet-induced hypercholesterolemia and is associated with a reduction in vascular nitric oxide production. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Maxwell, A. J, Niebauer, J., Lin, P. S, Tsao, P. S, Bernstein, D., Cooke, J. P Tags: Article Source Type: journals
The effect of l-arginine and creatine on vascular function and homocysteine metabolism
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In conclusion, the present study provides no evidence that l-arginine supplementation improves endothelial function and suggests that l-arginine may increase methylation demand. Creatine supplementation failed to alter the actions of l-arginine on vascular function or suppress methylation demand. The unexpected increase in homocysteine levels following creatine supplementation could have adverse effects and merits further study, since creatine is a commonly used dietary supplement. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Jahangir, E., Vita, J. A, Handy, D., Holbrook, M., Palmisano, J., Beal, R., Loscalzo, J., Eberhardt, R. T Tags: Article Source Type: journals
Correlates of carotid stenosis in patients undergoing coronary artery bypass grafting - a case control study
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In conclusion, the presence of a carotid bruit or PAD predicts an increased likelihood of significant carotid artery disease in patients undergoing CABG. Unlike previous studies, LMCA or extent of CAD did not correlate with significant carotid artery disease. Using these predictive models, a prospective outcomes trial is required to validate these criteria. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Kiernan, T. J, Taqueti, V., Crevensten, G., Yan, B. P, Slovut, D. P, Jaff, M. R Tags: Article Source Type: journals
Carotid and femoral arterial wall changes and the prevalence of clinical cardiovascular disease
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In conclusion, the TPT and number of bifurcations with plaque are more strongly associated with the prevalence of CVD. These findings warrant investigation in prospective studies to document associations with incident CVD events. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Griffin, M., Nicolaides, A., Tyllis, T., Georgiou, N., Martin, R. M, Bond, D., Panayiotou, A., Tziakouri, C., Dore, C. J, Fessas, C. Tags: Article Source Type: journals
Interobserver variability of ankle-brachial index measurements at rest and post exercise in patients with intermittent claudication
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AbstractThe ankle–brachial index (ABI) post exercise is claimed to play a complementary role in the diagnosis or exclusion of intermittent claudication (IC). The interobserver variability of ABI measurements at rest and post exercise in patients with typical symptoms of IC is the subject of this study with emphasis on ABI post exercise. ABI at rest and post exercise were measured in both legs of 20 patients with typical symptoms of IC. After 15 minutes of rest these measurements were repeated by another observer. Analysis according to Bland–Altman was performed on 40 paired leg measurements at rest and 40 paire...
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: van Langen, H., van Gurp, J., Rubbens, L. Tags: Article Source Type: journals
Association of serum myeloperoxidase with the ankle-brachial index and peripheral arterial disease
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AbstractMyeloperoxidase (MPO) is an enzymatic mediator of several inflammatory cascades and higher serum levels have been associated with increased risk of adverse cardiovascular events. We investigated the association of serum MPO with the ankle–brachial index (ABI) and peripheral arterial disease (PAD) in a bi-ethnic cohort of African-Americans and non-Hispanic white individuals. Participants included 1324 African-Americans (mean age 64 years, 71% women) and 1237 non-Hispanic white individuals (mean age 59 years, 57% women) belonging to hypertensive sibships. Serum levels of MPO were measured by solid phase sandwic...
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Ali, Z., Sarcia, P., Mosley, T. H, Kondragunta, V., Kullo, I. J Tags: Article Source Type: journals
Efficacy of arm-ergometry versus treadmill exercise training to improve walking distance in patients with claudication
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In conclusion, these pilot data demonstrate for the first time that dynamic arm exercise training can improve walking capability in people with peripheral arterial disease (PAD)-induced claudication compared to participants receiving usual care and that improvement was not different from that seen with treadmill walking exercise training. Dynamic arm exercise may be a therapeutic exercise option for patients with PAD. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Treat-Jacobson, D., Bronas, U. G, Leon, A. S Tags: Article Source Type: journals
Physical activity during daily life and brachial artery flow-mediated dilation in peripheral arterial disease
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In conclusion, higher levels of physical activity during daily life are associated significantly and independently with better brachial artery FMD among individuals with PAD, even after adjusting for confounders. ClinicalTrials.gov Identifier: NCT00106327. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 2, 2009 Category: Internal Medicine Authors: Payvandi, L., Dyer, A., McPherson, D., Ades, P., Stein, J., Liu, K., Ferrucci, L., Criqui, M. H, Guralnik, J. M, Lloyd-Jones, D., Kibbe, M. R, Liang, S. T, Kane, B., Pearce, W. H, Verta, M., McCarthy, W. J, Schneider, J. R, Shroff, A., McDermott, M. M Tags: Article Source Type: journals
Abstracts submitted for the 2009 SVM Annual Meeting: 20th Annual Scientific Sessions
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Tags: Article Source Type: journals
Endovascular coil embolization of pulmonary AV malformations in a patient with hereditary hemorrhagic telangiectasia
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Thatipelli, M. R, Morris, P., Rajachandran, M. S Tags: Article Source Type: journals
Cell therapies for therapeutic angiogenesis: back to the bench
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AbstractThe discovery, over a decade ago, of endothelial progenitor cells that are able to participate in neovascularization of adult tissue has been greeted enthusiastically because of the potential for new cell-based therapies for therapeutic angiogenesis. Since that time, an ever-growing list of candidate cells has been proposed for cardiovascular regeneration. However, to date, pre-clinical and clinical studies evaluating the therapeutic potential of various cell therapies have reported conflicting results, generating controversy. Key issues within the field of cell therapy research include a lack of uniform cellular d...
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Sieveking, D. P, Ng, M. K. Tags: Article Source Type: journals
A rare case of leiomyosarcoma arising from a femoral vein tributary: a case report
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We report a case of leiomyosarcoma originating from a tributary of the femoral vein in a 55-year-old woman. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Paraskevas, N., Castier, Y., Dauge, M.-C., Alsac, J.-M., Francis, F., El Batti, S., Leseche, G. Tags: Article Source Type: journals
Digital thermal monitoring of vascular function: a novel tool to improve cardiovascular risk assessment
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This study demonstrates that vascular dysfunction measured by DTM is associated with CHD and an increased FRS, and could potentially be used to identify high-risk patients. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Gul, K. M, Ahmadi, N., Wang, Z., Jamieson, C., Nasir, K., Metcalfe, R., Hecht, H. S, Hartley, C. J, Naghavi, M. Tags: Article Source Type: journals
The beneficial effects of breastfeeding on microvascular function in 11- to 14-year-old children
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AbstractInfant feeding practices have an impact on health in later life, although the evidence for its effects on cardiovascular health is not so clear. The aim of this study was to investigate the relationship between breastfeeding in infancy and vascular function in later childhood. Infant feeding data, together with demographic and clinical information, were obtained prospectively from a cohort of children from birth until 2 years of age. Vascular function was assessed in 159 children, now aged 11–14 years, by measuring their skin microvascular responses to iontophoretic administration of the endothelium-dependent...
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Khan, F., Green, F. C, Forsyth, J S., Greene, S. A, Newton, D. J, Belch, J. J. Tags: Article Source Type: journals
Total serum bilirubin does not affect vascular reactivity in patients with diabetes
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AbstractBilirubin may have a major role in the prevention of cardiovascular disease based on recent data regarding its anti-oxidant properties. We determined the relationship between total serum bilirubin and vascular reactivity in a large cohort of individuals with diabetes, a disease associated with known oxidant stress. We studied 302 individuals: 52 controls, 37 with type 1 diabetes, 213 with type 2 diabetes. High-resolution ultrasound was used to measure flow-mediated dilation (FMD; endothelium-dependent) and nitroglycerin-induced dilation (NID, endothelium-independent) of the brachial artery. Laser Doppler perfusion ...
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Yeh, S. Y., Doupis, J., Rahangdale, S., Horr, S., Malhotra, A., Veves, A. Tags: Article Source Type: journals
Short series of emergency stent-graft repair of symptomatic penetrating thoracic aortic ulcers (PTAU)
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In conclusion, endovascular management of acute PTAU appears effective and durable with mortality rates that are likely to be better than for open surgery. However, haemodynamic compromise at presentation remains a robust denominator of over-all survival. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Girn, H., McPherson, S, Nicholson, T, Mavor, A., Homer-Vanniasinkam, S, Gough, M. Tags: Article Source Type: journals
An approach to cultural adaptation and validation: the Intermittent Claudication Questionnaire
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In conclusion, the Turkish version of the ICQ, which is a disease-specific, self-administered, and practical instrument, is reliable and valid. We recommend its use to assess the effect of IC on the quality of life of patients in clinical trials and in daily clinical practice. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Ketenci, B., Tuygun, A. K., Gorur, A., Bicer, M., Ozay, B., Gunay, R., Guney, M. R., Sargin, M., Cimen, S., Demirtas, M. M., Yekeler, I. Tags: Article Source Type: journals
A prognostic model for amputation in critical lower limb ischemia
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In conclusion, in patients with critical lower limb ischemia, the presence of ischemic skin lesions and the described radiological arterial disease score can be used to estimate amputation risk. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Klomp, H., Steyerberg, E., Wittens, C., van Urk, H, Habbema, J., For the ESES study group Tags: Article Source Type: journals
Community trial of home-based exercise therapy for intermittent claudication
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AbstractPeripheral arterial disease (PAD) is a common disease, and intermittent claudication (IC) is a life-changing symptom. Exercise therapy has been demonstrated to be an effective treatment for IC in a supervised setting; however, most insurance carriers do not reimburse for exercise therapy. As a result, non-supervised programs have largely replaced supervised programs, despite limited evidence of their benefit. In this retrospective study of the results of our routine care, we analyzed the outcomes of a structured 6-month home-based exercise program for IC. A total of 120 patients with PAD and IC were enrolled in a h...
Source: Vascular Medicine recent issues - April 14, 2009 Category: Internal Medicine Authors: Mouser, M. J, Zlabek, J. A, Ford, C. L, Mathiason, M. A Tags: Article Source Type: journals
Internal mammary artery and inferior epigastric artery collateralization in a patient with aortoiliac occlusive disease
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Kolluri, R., Holloway, R., Mishkel, G. Tags: Article Source Type: journals
Parkes Weber syndrome: bone involvement visualized by computed tomography angiography
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(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Straface, G., Biscetti, F., Ghirlanda, G., Flex, A. Tags: Article Source Type: journals
Collagens in the progression and complications of atherosclerosis
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Abstract Collagens constitute a major portion of the extracellular matrix in the atherosclerotic plaque, where they contribute to the strength and integrity of the fibrous cap, and also modulate cellular responses via specific receptors and signaling pathways. This review focuses on the diverse roles that collagens play in atherosclerosis; regulating the infiltration and differentiation of smooth muscle cells and macrophages; controlling matrix remodeling through feedback signaling to proteinases; and influencing the development of atherosclerotic complications such ...
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Adiguzel, E., Ahmad, P. J, Franco, C., Bendeck, M. P Tags: Article Source Type: journals
The role of optical coherence tomography in vascular medicine
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AbstractOptical coherence tomography (OCT) is an emerging imaging modality that provides high-resolution, microstructural information on atherosclerotic plaques in biological systems. Intracoronary OCT can identify thin-cap fibroatheroma and other vulnerable plaques that may be responsible for acute coronary events. These characteristics make OCT helpful in guiding coronary management and interventions, including stent apposition and early identification of procedure-related complications. OCT is being assessed for its potential role in carotid plaque characterization and in the diagnosis of peripheral arterial atheroscler...
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Farooq, M. U, Khasnis, A., Majid, A., Kassab, M. Y Tags: Article Source Type: journals
Peripheral arterial disease and cognitive function
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AbstractAs a marker of generalized atherosclerosis, peripheral arterial disease (PAD) has implications not only for the affected lower extremity but also to overall cardiovascular health. It confers an increased risk of non-fatal and fatal vascular events which increases with the severity of the disease. Patient-based studies have shown that individuals with advanced PAD tend to perform poorly on cognitive tests compared to controls. In population studies, PAD is associated with an increased cognitive decline independently of previous cerebrovascular disease and cardiovascular risk factors. A low ankle–brachial index...
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Rafnsson, S. B, Deary, I. J, Fowkes, F. Tags: Article Source Type: journals
Endovascular treatment of septic thrombophlebitis: a case report of a rare complication and review of the literature
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We report a case of severe deep venous thrombosis (DVT) treated with multimodality therapy that was complicated by sepsis due to thrombus likely infected by Salmonella virchow. We review the current therapeutic options in the therapy of severe DVT and cardiovascular pathology associated with non-typhoid Salmonella. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Schifferdecker, B., Merchan, J. A., Ahmar, C., Worthington, M., Griben, A., Schainfeld, R. M, Soukas, P. A Tags: Article Source Type: journals
Dual roles of tumor necrosis factor-{alpha} receptor-1 in a mouse model of hindlimb ischemia
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AbstractSignals in the tumor necrosis factor (TNF-) pathway are upregulated after ischemia, yet its role in peripheral ischemia remains unclear. We investigated the effect of TNF- receptor 1 (TNFR-1) in acute limb ischemia of TNFR-1 knockout (TNFR-1–/–) and wild type (WT, TNFR-1+/+) mice. Laser Doppler scanning showed that although pre-ischemia blood flow levels were similar in these mice, the limb reperfusion after ischemia was significantly higher in TNFR-1–/– mice 1–7 days after injury. Consistently, fewer TUNEL-positive cells, less DNA fragmentation, and a lower ischemic score were detecte...
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Jiang, J., Wang, J., Li, C., Yu, S. P., Wei, L. Tags: Article Source Type: journals
Estradiol-induced, endothelial progenitor cell-mediated neovascularization in male mice with hind-limb ischemia
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AbstractWe investigated whether administration of estradiol to male mice augments mobilization of bone marrow-derived endothelial progenitor cells (EPC) and incorporation into foci of neovascularization after hind-limb ischemia, thereby contributing to blood flow restoration. Mice were randomized and implanted with placebo pellets or pellets containing low-dose estradiol (0.39 mg) or high-dose estradiol (1.7 mg). Hind-limb ischemia was induced by unilateral resection of the left femoral artery 1 week after pellet implantation, then EPC mobilization and functional recovery was evaluated. EPC recruitment was assessed in mice...
Source: Vascular Medicine recent issues - January 14, 2009 Category: Internal Medicine Authors: Ruifrok, W.-P. T, de Boer, R. A, Iwakura, A., Silver, M., Kusano, K., Tio, R. A, Losordo, D. W Tags: Article Source Type: journals
