World Journal of Gastroenterology
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Overview of immunosuppression in liver transplantation.
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Continued advances in surgical techniques and immunosuppressive therapy have allowed liver transplantation to become an extremely successful treatment option for patients with end-stage liver disease. Beginning with the revolutionary discovery of cyclosporine in the 1970s, immunosuppressive regimens have evolved greatly and current statistics confirm one-year graft survival rates in excess of 80%. Immunosuppressive regimens include calcineurin inhibitors, anti-metabolites, mTOR inhibitors, steroids and antibody-based therapies. These agents target different sites in the T cell activation cascade, usually by inhibiting ...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Pillai AA, Levitsky J Tags: World J Gastroenterol Source Type: journals
Prevalence, predictors, and clinical consequences of medical adherence in IBD: How to improve it?Email this article to a colleague.
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Inflammatory bowel diseases (IBD) are chronic diseases with a relapsing-remitting disease course necessitating lifelong treatment. However, non-adherence has been reported in over 40% of patients, especially those in remission taking maintenance therapies for IBD. The economical impact of non-adherence to medical therapy including absenteeism, hospitalization risk, and the health care costs in chronic conditions, is enormous. The causes of medication non-adherence are complex, where the patient-doctor relationship, treatment regimen, and other disease-related factors play key roles. Moreover, subjective assessment migh...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Lakatos PL Tags: World J Gastroenterol Source Type: journals
Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009.Email this article to a colleague.
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Several advances in diagnosis, treatment and palliation of cholangiocarcinoma (CC) have occurred in the last decades. A multidisciplinary approach to this disease is therefore recommended. CC is a relatively rare tumor and the main risk factors are: chronic inflammation, genetic predisposition and congenital abnormalities of the biliary tree. While the incidence of intra-hepatic CC is increasing, the incidence of extra-hepatic CC is trending down. The only curative treatment for CC is surgical resection with negative margins. Liver transplantation has been proposed only for selected patients with hilar CC that cannot b...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Aljiffry M, Walsh MJ, Molinari M Tags: World J Gastroenterol Source Type: journals
Emerging treatments for complex perianal fistula in Crohn's disease.Email this article to a colleague.
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Complex perianal fistulas have a negative impact on the quality of life of sufferers and should be treated. Correct diagnosis, characterization and classification of the fistulas are essential to optimize treatment. Nevertheless, in the case of patients whose fistulas are associated with Crohn's disease, complete closure is particularly difficult to achieve. Systemic medical treatments (antibiotics, thiopurines and other immunomodulatory agents, and, more recently, anti-tumor necrosis factor-alpha agents such as infliximab) have been tried with varying degrees of success. Combined medical (including infliximab) and les...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Taxonera C, Schwartz DA, García-Olmo D Tags: World J Gastroenterol Source Type: journals
Meta-analysis and systematic review of colorectal endoscopic mucosal resection.Email this article to a colleague.
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CONCLUSION: EMR is an effective technique for the resection of large colorectal polyps and offers an alternative to surgery.
PMID: 19750569 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Puli SR, Kakugawa Y, Gotoda T, Antillon D, Saito Y, Antillon MR Tags: World J Gastroenterol Source Type: journals
Sirolimus, bevacizumab, 5-Fluorouracil and irinotecan for advanced colorectal cancer: A pilot study.Email this article to a colleague.
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CONCLUSION: The combination regimen of 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in advanced colorectal carcinoma after failure of classical treatment is feasible and promising. Further evaluation of this combination is required.
PMID: 19750570 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Ghiringhelli F, Guiu B, Chauffert B, Ladoire S Tags: World J Gastroenterol Source Type: journals
Effect of early propranolol administration on portal hypertensive gastropathy in cirrhotic rats.Email this article to a colleague.
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CONCLUSION: Early propranolol's administration in portal hypertensive cirrhotic rats seems to prevent intense gastric vascular congestion that characterizes portal hypertensive gastropathy.
PMID: 19750571 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Rafailidis S, Demertzidis C, Ballas K, Alatsakis M, Symeonidis N, Pavlidis T, Psarras K, Tzioufa-Asimakopoulou V, Sakadamis A Tags: World J Gastroenterol Source Type: journals
Does Helicobacter pylori eradication therapy for peptic ulcer prevent gastric cancer?Email this article to a colleague.
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CONCLUSION: H pylori eradication therapy for peptic ulcer patients with a mean age of 52.9 years at registration did not significantly decrease the incidence of gastric cancer.
PMID: 19750572 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Mabe K, Takahashi M, Oizumi H, Tsukuma H, Shibata A, Fukase K, Matsuda T, Takeda H, Kawata S Tags: World J Gastroenterol Source Type: journals
Small sphincterotomy combined with endoscopic papillary large balloon dilation versus sphincterotomy.Email this article to a colleague.
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CONCLUSION: SES + ELBD did not show significant benefits compared to conventional EST, especially for the removal of large (>/= 15 mm) bile duct stones.
PMID: 19750573 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Kim HG, Cheon YK, Cho YD, Moon JH, Park do H, Lee TH, Choi HJ, Park SH, Lee JS, Lee MS Tags: World J Gastroenterol Source Type: journals
Prognostic analysis of patients with pancreatic head adenocarcinoma less than 2 cm undergoing resection.Email this article to a colleague.
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CONCLUSION: S-PAC patients should not be regarded as early PAC. Only higher albumin level (> 3.5 g/dL) and early stage disease (stage I, II) were the favorable prognosis factors for S-PAC patients.
PMID: 19750574 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Chiang KC, Yeh CN, Lee WC, Jan YY, Hwang TL Tags: World J Gastroenterol Source Type: journals
Baseline predictors of virological response for chronic hepatitis B patients.Email this article to a colleague.
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CONCLUSION: Baseline serum ALT, TSH, and TT4 levels, especially in combination, have high predictive values of virological response to Peginterferon alpha-2b in HBeAg-positive CHB patients.
PMID: 19750575 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Wu XJ, Wang Y, Chen J, Wang GQ Tags: World J Gastroenterol Source Type: journals
Expression of thymidylate synthase and glutathione-s-transferase pi in patients with esophageal squamous cell carcinoma.Email this article to a colleague.
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CONCLUSION: The expression of TS and of GST-pi may be used as molecular markers for the characterization of ESCC. Poorly-differentiated cells showed increased expression of TS and reduced expression of GST-pi.
PMID: 19750576 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Huang JX, Li FY, Xiao W, Song ZX, Qian RY, Chen P, Salminen E Tags: World J Gastroenterol Source Type: journals
Application of endoscopic hemoclips for nonvariceal bleeding in the upper gastrointestinal tract.Email this article to a colleague.
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CONCLUSION: Endoscopic hemoclip application was an effective and safe method for acute nonvariceal bleeding in the upper GI tract with satisfactory outcomes.
PMID: 19750577 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Guo SB, Gong AX, Leng J, Ma J, Ge LM Tags: World J Gastroenterol Source Type: journals
Cytomegalovirus enteritis mimicking Crohn's disease in a lupus nephritis patient: A case report.Email this article to a colleague.
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This report highlights the importance of accurate histological diagnosis and clinical follow-up of lupus patients with GI symptoms undergoing intense immunosuppression.
PMID: 19750578 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Khan FN, Prasad V, Klein MD Tags: World J Gastroenterol Source Type: journals
Rejection of Permacol(R) mesh used in abdominal wall repair: A case report.Email this article to a colleague.
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Permacol(R) mesh has shown promise when used in abdominal wall repair, especially in the presence of a contaminated surgical field. This biomaterial, derived from porcine dermis collagen, has proposed advantages over synthetic materials due to increased biocompatibility and reduced foreign body reaction within human tissues. However, we present a case report describing a patient who displayed rejection to a Permacol(R) mesh when used in the repair of abdominal wound dehiscence following an emergency laparotomy. Review of the English language literature using PubMed and Medline, showed only two previously published case...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Wotton FT, Akoh JA Tags: World J Gastroenterol Source Type: journals
Resection of the uncinate process of the pancreas due to a ganglioneuroma.Email this article to a colleague.
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A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound (US). This investigation and subsequent contrast-enhanced computed tomography, magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA) revealed a 40 mm well-circumscribed mass in the uncinate process of the pancreas. Findings were suggestive of a mucinous or solid-cystic pseudopapillary tumor of the pancreas, although other lesions such as a non-functioning neuroendocrine tumor could not be ruled out. FNA samples were negative for malignant cells, but of limited value due to poor cellularit...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Poves I, Burdío F, Iglesias M, Martínez-Serrano MA, Aguilar G, Grande L Tags: World J Gastroenterol Source Type: journals
Novel ABCB11 mutations in a Thai infant with progressive familial intrahepatic cholestasis.Email this article to a colleague.
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We report a Thai female infant who presented with progressive cholestatic jaundice since 1 mo of age, with normal serum gamma-glutamyltransferase. Immunohistochemical staining of the liver did not demonstrate BSEP along the canaliculi, while multidrug resistance protein 3 was expressed adequately. Novel mutations in ABCB11, a four-nucleotide deletion in exon 3, c.90_93delGAAA, and a single-nucleotide insertion in exon 5, c.249_250insT, were identified, with confirmation in her parents. These mutations were predicted to lead to synthesis of truncated forms of BSEP. Immunostaining and mutation analysis thus established the d...
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Treepongkaruna S, Gaensan A, Pienvichit P, Luksan O, Knisely AS, Sornmayura P, Jirsa M Tags: World J Gastroenterol Source Type: journals
Primary squamous cell carcinoma of pancreas diagnosed by EUS-FNA: A case report.Email this article to a colleague.
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Squamous cell carcinoma of the pancreas has been sparsely described since the 1940s, and generally has a poor prognosis. Herein, we present a case of primary squamous cell carcinoma of the pancreas with liver metastasis, both confirmed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). To the best of our knowledge, this is the first case report in literature utilizing EUS-FNA for a cell-type specific diagnosis of primary pancreatic squamous cell carcinoma with a liver metastasis.
PMID: 19750582 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Lai LH, Romagnuolo J, Adams D, Yang J Tags: World J Gastroenterol Source Type: journals
Biomarkers for noninvasive biochemical diagnosis of nonalcoholic steatohepatitis: Tools or decorations?Email this article to a colleague.
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In light of the growing epidemics of nonalcoholic fatty liver disease (NAFLD), identification and validation of the novel biochemical surrogate markers for nonalcoholic steatohepatitis (NASH) are paramount to reduce the necessity for liver biopsy. The availability of such markers has tremendous potential to radically alter the management strategies of NAFLD patients and to monitor the disease activity. Although current biomarkers do not entirely fulfill the many requirements for the identification of patients with NASH, they should not discourage our quest, but remind us that we need to cognize the challenges ahead.
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Source: World Journal of Gastroenterology - September 13, 2009 Category: Gastroenterology Authors: Yilmaz Y, Dolar E Tags: World J Gastroenterol Source Type: journals
"World J Gastroenterol"[ta]; +221 new citationsEmail this article to a colleague.
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221 new pubmed citations were retrieved for your search.
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"World J Gastroenterol"[ta]
These pubmed results were generated on 2009/06/27PubMed, a service of the National Library of Medicine, includes over 15 million
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Source: World Journal of Gastroenterology - June 27, 2009 Category: Gastroenterology Tags: Report Source Type: journals
Alcohol and liver.Email this article to a colleague.
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PMID: 19325896 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 14, 2009 Category: Gastroenterology Authors: Osna NA Tags: World J Gastroenterol Source Type: journals
Liver disease in pregnancy.Email this article to a colleague.
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This article reviews the epidemiology, pathophysiology, diagnosis, and management of liver diseases seen in pregnancy.
PMID: 19248187 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Lee NM, Brady CW Tags: World J Gastroenterol Source Type: journals
Clinical application of hepatic CT perfusion.Email this article to a colleague.
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This article reviews the clinical application of hepatic x-ray computed tomography perfusion in some liver diseases.
PMID: 19248188 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Zhong L, Wang WJ, Xu JR Tags: World J Gastroenterol Source Type: journals
A rabbit model of pediatric nonalcoholic steatohepatitis: The role of adiponectin.Email this article to a colleague.
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CONCLUSION: This rabbit model produces the key features of pediatric NASH and may provide a realistic model for future studies. Adiponectin level partially reflects the severity of liver steatosis, but not the degree of liver inflammation.
PMID: 19248189 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Fu JF, Fang YL, Liang L, Wang CL, Hong F, Dong GP Tags: World J Gastroenterol Source Type: journals
Aspirin increases susceptibility of Helicobacter pylori to metronidazole by augmenting endocellular concentrations of antimicrobials.Email this article to a colleague.
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CONCLUSION: Although aspirin increases the susceptibility of H pylori to metronidazole, it has no effect on the mutations of rdxA gene of H pylori. Aspirin increases endocellular concentrations of antimicrobials probably by altering the OMP expression.
PMID: 19248190 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Zhang XP, Wang WH, Tian Y, Gao W, Li J Tags: World J Gastroenterol Source Type: journals
Hospitalized ulcerative colitis patients have an elevated risk of thromboembolic events.Email this article to a colleague.
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CONCLUSION: Patients with ulcerative colitis who do not undergo an operation during their hospitalization have similar or higher rates of thromboembolism than other medical patients who are considered to be high risk for thromboembolism.
PMID: 19248191 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Wang JY, Terdiman JP, Vittinghoff E, Minichiello T, Varma MG Tags: World J Gastroenterol Source Type: journals
Esophageal cell proliferation in gastroesophageal reflux disease: Clinical-morphological data before and after pantoprazole.Email this article to a colleague.
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CONCLUSION: Three months of pantoprazole therapy induced ultrastructural healing of mucosal damage in 89% and 93% of ERD and non-erosion patients, respectively. Moreover, long-term pantoprazole treatment may be helpful in increasing the capability for esophageal cell proliferation in GERD, particularly in ERD patients.
PMID: 19248192 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Calabrese C, Trere D, Liguori G, Gabusi V, Vici M, Cenacchi G, Derenzini M, Di Febo G Tags: World J Gastroenterol Source Type: journals
Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis.Email this article to a colleague.
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CONCLUSION: Angiotensin receptor blockers seem to be efficient in hypertension-associated NASH. Telmisartan showed a higher efficacy regarding insulin resistance and histology, perhaps because of its specific PPAR-gamma ligand effect.
PMID: 19248193 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Georgescu EF, Ionescu R, Niculescu M, Mogoanta L, Vancica L Tags: World J Gastroenterol Source Type: journals
Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease.Email this article to a colleague.
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CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management.
PMID: 19248194 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Hadithi M, Mulder CJ, Stam F, Azizi J, Crusius JB, Pena AS, Stehouwer CD, Smulders YM Tags: World J Gastroenterol Source Type: journals
Prevalence and risk factors of gastroesophageal reflux disease in Qashqai migrating nomads, southern Iran.Email this article to a colleague.
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CONCLUSION: The prevalence of GERD (33%) is very high in Qashqai migrating nomads which may be due to a lower socioeconomic and educational level of these people and difference in the life style. Older age, frequent consumption of fruits and vegetables, smoking and NSAIDs are risk factors for GERD in this population.
PMID: 19248195 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Mostaghni A, Mehrabani D, Khademolhosseini F, Masoumi SJ, Moradi F, Zare N, Saberi-Firoozi M Tags: World J Gastroenterol Source Type: journals
Point-of-care continuous (13)C -methacetin breath test improves decision making in acute liver disease: Results of a pilot clinical trial.Email this article to a colleague.
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CONCLUSION: The (13)C-MBT provides a rapid, non-invasive assessment of liver function in acute severe liver disease of diverse etiologies. The results of this pilot clinical trial suggest that the MBT may offer greater sensitivity than standard clinical tests for managing patients with severe acute liver disease.
PMID: 19248196 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Lalazar G, Adar T, Ilan Y Tags: World J Gastroenterol Source Type: journals
Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats.Email this article to a colleague.
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CONCLUSION: These results suggest that EA-mediated protection against ASA-induced ulceration in rats may occur via gastric defense components.
PMID: 19248197 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Hwang HS, Han KJ, Ryu YH, Yang EJ, Kim YS, Jeong SY, Lee YS, Lee MS, Koo ST, Choi SM Tags: World J Gastroenterol Source Type: journals
Surgical palliation of unresectable pancreatic head cancer in elderly patients.Email this article to a colleague.
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CONCLUSION: Surgical palliation does not increase the morbidity or mortality rates, but it does increase the survival rate and improve the quality of life in elderly patients with unresectable pancreatic head cancer.
PMID: 19248198 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Hwang SI, Kim HO, Son BH, Yoo CH, Kim H, Shin JH Tags: World J Gastroenterol Source Type: journals
Genetic diagnosis strategy of hereditary non-polyposis colorectal cancer.Email this article to a colleague.
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CONCLUSION: Scientific and rational detection strategy can improve the detection rate of HNPCC. Based on traditional molecular genetics and combined with epigenetics, multiple detection methods can accurately diagnose HNPCC.
PMID: 19248199 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Sheng JQ, Zhang H, Ji M, Fu L, Mu H, Zhang MZ, Huang JS, Han M, Li AQ, Wei Z, Sun ZQ, Wu ZT, Xia CH, Li SR Tags: World J Gastroenterol Source Type: journals
Comparative study of omeprazole, lansoprazole, pantoprazole and esomeprazole for symptom relief in patients with reflux esophagitis.Email this article to a colleague.
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CONCLUSION: Esomeprazole may be more effective than omeprazole, lansoprazole, and pantoprazole for the rapid relief of heartburn symptoms and acid reflux symptoms in patients with reflux esophagitis.
PMID: 19248200 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Zheng RN Tags: World J Gastroenterol Source Type: journals
Impact of human immunodeficiency virus infection on the course of hepatitis C virus infection: A meta-analysis.Email this article to a colleague.
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CONCLUSION: Without highly active antiretroviral therapies (HAART), HIV accelerates HCV disease progression, including death, histological fibrosis/cirrhosis and decompensated liver disease. However, the rate of hepatocellular carcinoma is similar in persons who had HCV infection and were positive for HIV or negative for HIV.
PMID: 19248201 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Deng LP, Gui XE, Zhang YX, Gao SC, Yang RR Tags: World J Gastroenterol Source Type: journals
Severe autoimmune hepatitis triggered by varicella zoster infection.Email this article to a colleague.
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We report a case of severe AIH following varicella zoster infection in a 23-year-old man, and speculate that, based on the molecular mimicry hypothesis, the liver damage was caused by an immune cross reaction to the viral proteins. Varicella-zoster-induced AIH has not been reported previously.
PMID: 19248202 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Al-Hamoudi WK Tags: World J Gastroenterol Source Type: journals
Abscess in the inguinal hernial sac after peritonitis surgery: A case report.Email this article to a colleague.
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In this paper, we report an extremely rare case of an abscess that developed in the inguinal hernial sac after surgery for peritonitis. A 60-year-old man underwent laparoscopic low anterior resection for rectal cancer. One day after this operation, peritoneal drainage and ileostomy were performed for rectal anastomotic leakage. Five days after the second operation, computed tomography revealed an abscess in the left inguinal hernial sac. Subsequently, hernioplasty and resection of the inflamed sac were performed.
PMID: 19248203 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Ikeda S, Takeda H, Yoshimitsu M, Hinoi T, Yoshida M, Sumitani D, Takakura Y, Kawaguchi Y, Shimomura M, Tokunaga M, Kawahori K, Ohdan H, Okajima M Tags: World J Gastroenterol Source Type: journals
Pancreatic tuberculosis masquerading as pancreatic serous cystadenoma.Email this article to a colleague.
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We report a patient who had solitary pancreatic tuberculosis masquerading as pancreatic serous cystadenoma.
PMID: 19248204 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Hong SG, Kim JS, Joo MK, Lee KG, Kim KH, Oh CR, Park JJ, Bak YT Tags: World J Gastroenterol Source Type: journals
Nodular liver lesions involving multiple myeloma: A case report and literature review.Email this article to a colleague.
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In this report, a literature review of liver lesions involving multiple myeloma is also provided.
PMID: 19248205 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Wu XN, Zhao XY, Jia JD Tags: World J Gastroenterol Source Type: journals
Triptolide and management of systemic malignancies besides pancreatic carcinomas.Email this article to a colleague.
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The recent article by Zhou et al was highly interesting and thought provoking. The authors have clearly shown that triptolide administration is associated with up-regulation of the Bax gene, resulting in an attenuating effect on cell growth in gastrointestinal malignancies such as pancreatic carcinomas. The article by Zhou et al is all the more important because it highlights the rapidly increasing role of triplodide in the management of systemic malignancies. For instance, triptolide acts on the PI3K/Akt/NF-kappaB pathway, thereby enhancing apoptosis secondary to the administration of bortezomib in multiple myeloma ce...
Source: World Journal of Gastroenterology - February 28, 2009 Category: Gastroenterology Authors: Kapoor S Tags: World J Gastroenterol Source Type: journals
Anal transition zone in the surgical management of ulcerative colitis.Email this article to a colleague.
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Preservation of the anal transition zone has long been a significant source of controversy in the surgical management of ulcerative colitis. The two techniques for restorative proctocolectomy and ileal pouch anal anastomosis (RPC IPAA) in common practice are a stapled anastomosis and a handsewn anastomosis; these techniques differ in the amount of remaining rectal mucosa and therefore the presence of the anal transition zone following surgery. Each technique has advantages and disadvantages in long-term functional outcomes, operative and postoperative complications, and risk of neoplasia. Therefore, we propose a select...
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Holder-Murray J, Fichera A Tags: World J Gastroenterol Source Type: journals
Morphological, kinetic, membrane biochemical and genetic aspects of intestinal enteroplasticity.Email this article to a colleague.
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The process of intestinal adaptation ("enteroplasticity") is complex and multifaceted. Although a number of trophic nutrients and non-nutritive factors have been identified in animal studies, successful, reproducible clinical trials in humans are awaited. Understanding mechanisms underlying this adaptive process may direct research toward strategies that maximize intestinal function and impart a true clinical benefit to patients with short bowel syndrome, or to persons in whom nutrient absorption needs to be maximized. In this review, we consider the morphological, kinetic and membrane biochemical aspects of enteroplas...
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Drozdowski LA, Clandinin MT, Thomson AB Tags: World J Gastroenterol Source Type: journals
Epidemiology and gene markers of ulcerative colitis in the Chinese.Email this article to a colleague.
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Inflammatory bowel disease (IBD) includes two similar yet distinct conditions called ulcerative colitis (UC) and Crohn's disease (CD). These diseases affect the digestive system and cause the inflammation of intestinal tissue, form sores and bleed easily. Most children with IBD are diagnosed in late childhood and adolescence. However, both UC and CD have been reported as early as in infancy. Most information pertaining to the epidemiology of IBD is based upon adult studies. Symptoms include abdominal pain, cramping, fatigue and diarrhea. Genetic factors play a significant role in determining IBD susceptibility. Epidemi...
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Yun J, Xu CT, Pan BR Tags: World J Gastroenterol Source Type: journals
Bile acids: Chemistry, physiology, and pathophysiology.Email this article to a colleague.
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The family of bile acids includes a group of molecular species of acidic steroids with very peculiar physical-chemical and biological characteristics. They are synthesized by the liver from cholesterol through several complementary pathways that are controlled by mechanisms involving fine-tuning by the levels of certain bile acid species. Although their best-known role is their participation in the digestion and absorption of fat, they also play an important role in several other physiological processes. Thus, genetic abnormalities accounting for alterations in their synthesis, biotransformation and/or transport may re...
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Monte MJ, Marin JJ, Antelo A, Vazquez-Tato J Tags: World J Gastroenterol Source Type: journals
Excretion of biliary compounds during intrauterine life.Email this article to a colleague.
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In adults, the hepatobiliary system, together with the kidney, constitute the main routes for the elimination of several endogenous and xenobiotic compounds into bile and urine, respectively. However, during intrauterine life the biliary route of excretion for cholephilic compounds, such as bile acids and biliary pigments, is very poor. Although very early in pregnancy the fetal liver produces bile acids, bilirubin and biliverdin, these compounds cannot be efficiently eliminated by the fetal hepatobiliary system, owing to the immaturity of the excretory machinery in the fetal liver. Therefore, the potentially harmful a...
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Macias RI, Marin JJ, Serrano MA Tags: World J Gastroenterol Source Type: journals
Imaging features of solid pseudopapillary tumor of the pancreas on multi-detector row computed tomography.Email this article to a colleague.
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CONCLUSION: Vascular and capsular invasion with superimposed spread into the adjacent pancreatic parenchyma and nearby structures in SPTs of the pancreas can be accurately revealed by MDCT preoperatively. These imaging findings are predictive of the malignant potential associated with the aggressive behavior of the tumor, even in the pathologically benign cases.
PMID: 19230043 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Wang DB, Wang QB, Chai WM, Chen KM, Deng XX Tags: World J Gastroenterol Source Type: journals
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis.Email this article to a colleague.
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CONCLUSION: Progress from adhesion to detachment of EC9706 cells causes DR5 relocalization, and promotes cytoplasmic translocation of DR5 to cell surfaces via a Golgi-dependent pathway. Moreover, it might also result in DR5 aggregation to render apoptosis of detached cells.
PMID: 19230044 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Liu GC, Zhang J, Liu SG, Gao R, Long ZF, Tao K, Ma YF Tags: World J Gastroenterol Source Type: journals
Correlation analysis of celiac sprue tissue transglutaminase and deamidated gliadin IgG/IgA.Email this article to a colleague.
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CONCLUSION: These data demonstrate that the production of anti-tTG IgA is directly correlated to the production of anti-DGP IgG and IgA, whereas anti-tTG IgG is only weakly correlated. This result therefore supports the hapten-carrier theory that in well-established celiac patients anti-tTG IgA is produced by a set of B cells that are reacting against the complex of tTG-DGP in the absence of a tTG-specific T cell.
PMID: 19230045 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Marietta EV, Rashtak S, Murray JA Tags: World J Gastroenterol Source Type: journals
Epidemiology of hepatitis B virus infection in Albania.Email this article to a colleague.
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CONCLUSION: Despite the estimated two-fold reduction of HBsAg prevalence in the general population from about 18%-19% to 9.5%, Albania remains a highly endemic country (i.e. over 8% of HBsAg prevalence rate).
PMID: 19230046 [PubMed - in process] (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 21, 2009 Category: Gastroenterology Authors: Resuli B, Prifti S, Kraja B, Nurka T, Basho M, Sadiku E Tags: World J Gastroenterol Source Type: journals
