Dynamic ultrasonography for optimizing treatment position in superior mesenteric artery syndrome: Two case reports and review of literature
CONCLUSION: The optimal position for SMA syndrome varies among individuals. Dynamic US appears to be a valuable tool in improving patient outcomes.PMID:38414592 | PMC:PMC10895595 | DOI:10.3748/wjg.v30.i5.499 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Nobuaki Hasegawa Akihiko Oka Muyiwa Awoniyi Yuri Yoshida Hiroshi Tobita Norihisa Ishimura Shunji Ishihara Source Type: research

Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1
CONCLUSION: For mild to moderate GOV1, patients with EBL had a greater one-time varix eradication rate, a greater 6-wk operation-related ulcer healing rate, a lower delayed rebleeding rate and a lower cost than patients with TAI.PMID:38414583 | PMC:PMC10895593 | DOI:10.3748/wjg.v30.i5.440 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Yue Deng Ya Jiang Tong Jiang Ling Chen Hai-Jun Mou Bi-Guang Tuo Guo-Qing Shi Source Type: research

Prevention of hepatitis B reactivation in patients with hematologic malignancies treated with novel systemic therapies: Who and Why?
World J Gastroenterol. 2024 Feb 7;30(5):509-511. doi: 10.3748/wjg.v30.i5.509.ABSTRACTThe risk of reactivation in patients with chronic or past/resolved hepatitis B virus (HBV) infection receiving chemotherapy or immunosuppressive drugs is a well-known possibility. The indication of antiviral prophylaxis with nucleo(t)side analogue is given according to the risk of HBV reactivation of the prescribed therapy. Though the advent of new drugs is occurring in all the field of medicine, in the setting of hematologic malignancies the last few years have been characterized by several drug classes and innovative cellular treatment. ...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Matteo Tonnini Clara Solera Horna Luca Ielasi Source Type: research

Nicotinamide adenine dinucleotide phosphate oxidase in pancreatic diseases: Mechanisms and future perspectives
World J Gastroenterol. 2024 Feb 7;30(5):429-439. doi: 10.3748/wjg.v30.i5.429.ABSTRACTPancreatitis and pancreatic cancer (PC) stand as the most worrisome ailments affecting the pancreas. Researchers have dedicated efforts to unraveling the mechanisms underlying these diseases, yet their true nature continues to elude their grasp. Within this realm, oxidative stress is often believed to play a causal and contributory role in the development of pancreatitis and PC. Excessive accumulation of reactive oxygen species (ROS) can cause oxidative stress, and the key enzyme responsible for inducing ROS production in cells is nicotina...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Ya-Wei Bi Long-Song Li Nan Ru Bo Zhang Xiao Lei Source Type: research

Development and validation of a prediction model for early screening of people at high risk for colorectal cancer
CONCLUSION: The early-screening nomogram model for CRC prediction in high-risk populations developed in this study based on age, BMI, WC, lifestyle, and family history exhibited high accuracy.PMID:38414586 | PMC:PMC10895599 | DOI:10.3748/wjg.v30.i5.450 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Ling-Li Xu Yi Lin Li-Yuan Han Yue Wang Jian-Jiong Li Xiao-Yu Dai Source Type: research

Recombinant adeno-associated virus 8-mediated inhibition of microRNA let-7a ameliorates sclerosing cholangitis in a clinically relevant mouse model
CONCLUSION: Our study demonstrates that a rAAV8 vector designed for liver-specific inhibition of let-7a-5p can potently ameliorate symptoms in a xenobiotic-induced mouse model of sclerosing cholangitis, which provides a possible clinical translation of PSC of human.PMID:38414587 | PMC:PMC10895596 | DOI:10.3748/wjg.v30.i5.471 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Hui Hua Qian-Qian Zhao Miriam Nkesichi Kalagbor Guo-Zhi Yu Man Liu Zheng-Rui Bian Bei-Bei Zhang Qian Yu Yin-Hai Xu Ren-Xian Tang Kui-Yang Zheng Chao Yan Source Type: research

Leveraging machine learning for early recurrence prediction in hepatocellular carcinoma: A step towards precision medicine
World J Gastroenterol. 2024 Feb 7;30(5):424-428. doi: 10.3748/wjg.v30.i5.424.ABSTRACTThe high rate of early recurrence in hepatocellular carcinoma (HCC) post curative surgical intervention poses a substantial clinical hurdle, impacting patient outcomes and complicating postoperative management. The advent of machine learning provides a unique opportunity to harness vast datasets, identifying subtle patterns and factors that elude conventional prognostic methods. Machine learning models, equipped with the ability to analyse intricate relationships within datasets, have shown promise in predicting outcomes in various medical...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Abhimati Ravikulan Kamran Rostami Source Type: research

Can serum immunoglobulin G4 levels and age serve as reliable predictors of relapse in autoimmune pancreatitis?
In conclusion, the paper by Zhou et al offers plausible, though not entirely compelling, evidence suggesting a predictive role of elevated serum IgG4 levels and advanced age in AIP relapse. The foundation for future investigations lies in ensuring a reliable diagnosis and accurate disease subtyping, heavily dependent on obtaining histological specimens. In this regard, endoscopic ultrasound-guided fine-needle biopsy emerges as a pivotal component of the diagnostic process, contributing to mitigating biases in future explorations of the disease.PMID:38414589 | PMC:PMC10895594 | DOI:10.3748/wjg.v30.i5.512 (Source: World Jour...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Jun-Min Song Si-Yu Sun Source Type: research

Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China
CONCLUSION: Abdominal high-frequency ultrasound can detect CE1 hydatid cysts. The laparoscopic technique serves as a more effective diagnostic and therapeutic tool for CE.PMID:38414590 | PMC:PMC10895592 | DOI:10.3748/wjg.v30.i5.462 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Yu-Peng Li Jie Zhang Zhi-De Li Chao Ma Guang-Lei Tian Yuan Meng Xiong Chen Zhi-Gang Ma Source Type: research

Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells
CONCLUSION: This study revealed for the first time that BAs could inhibit ferroptosis sensitivity through the FXR-BACH1-GSH-GPX4 axis in GC cells. This work provided new insights into the mechanism associated with BA-mediated promotion of GC and may help identify potential therapeutic targets for GC patients with BAs reflux.PMID:38414591 | PMC:PMC10895598 | DOI:10.3748/wjg.v30.i5.485 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Chu-Xuan Liu Ying Gao Xiu-Fang Xu Xin Jin Yun Zhang Qian Xu Huan-Xin Ding Bing-Jun Li Fang-Ke Du Lin-Chuan Li Ming-Wei Zhong Jian-Kang Zhu Guang-Yong Zhang Source Type: research

Dynamic ultrasonography for optimizing treatment position in superior mesenteric artery syndrome: Two case reports and review of literature
CONCLUSION: The optimal position for SMA syndrome varies among individuals. Dynamic US appears to be a valuable tool in improving patient outcomes.PMID:38414592 | PMC:PMC10895595 | DOI:10.3748/wjg.v30.i5.499 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Nobuaki Hasegawa Akihiko Oka Muyiwa Awoniyi Yuri Yoshida Hiroshi Tobita Norihisa Ishimura Shunji Ishihara Source Type: research

Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1
CONCLUSION: For mild to moderate GOV1, patients with EBL had a greater one-time varix eradication rate, a greater 6-wk operation-related ulcer healing rate, a lower delayed rebleeding rate and a lower cost than patients with TAI.PMID:38414583 | PMC:PMC10895593 | DOI:10.3748/wjg.v30.i5.440 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Yue Deng Ya Jiang Tong Jiang Ling Chen Hai-Jun Mou Bi-Guang Tuo Guo-Qing Shi Source Type: research

Prevention of hepatitis B reactivation in patients with hematologic malignancies treated with novel systemic therapies: Who and Why?
World J Gastroenterol. 2024 Feb 7;30(5):509-511. doi: 10.3748/wjg.v30.i5.509.ABSTRACTThe risk of reactivation in patients with chronic or past/resolved hepatitis B virus (HBV) infection receiving chemotherapy or immunosuppressive drugs is a well-known possibility. The indication of antiviral prophylaxis with nucleo(t)side analogue is given according to the risk of HBV reactivation of the prescribed therapy. Though the advent of new drugs is occurring in all the field of medicine, in the setting of hematologic malignancies the last few years have been characterized by several drug classes and innovative cellular treatment. ...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Matteo Tonnini Clara Solera Horna Luca Ielasi Source Type: research

Nicotinamide adenine dinucleotide phosphate oxidase in pancreatic diseases: Mechanisms and future perspectives
World J Gastroenterol. 2024 Feb 7;30(5):429-439. doi: 10.3748/wjg.v30.i5.429.ABSTRACTPancreatitis and pancreatic cancer (PC) stand as the most worrisome ailments affecting the pancreas. Researchers have dedicated efforts to unraveling the mechanisms underlying these diseases, yet their true nature continues to elude their grasp. Within this realm, oxidative stress is often believed to play a causal and contributory role in the development of pancreatitis and PC. Excessive accumulation of reactive oxygen species (ROS) can cause oxidative stress, and the key enzyme responsible for inducing ROS production in cells is nicotina...
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Ya-Wei Bi Long-Song Li Nan Ru Bo Zhang Xiao Lei Source Type: research

Development and validation of a prediction model for early screening of people at high risk for colorectal cancer
CONCLUSION: The early-screening nomogram model for CRC prediction in high-risk populations developed in this study based on age, BMI, WC, lifestyle, and family history exhibited high accuracy.PMID:38414586 | PMC:PMC10895599 | DOI:10.3748/wjg.v30.i5.450 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Ling-Li Xu Yi Lin Li-Yuan Han Yue Wang Jian-Jiong Li Xiao-Yu Dai Source Type: research