Recent Update on Acute Kidney Injury-to-Chronic Kidney Disease Transition
Yonsei Med J. 2024 May;65(5):247-256. doi: 10.3349/ymj.2023.0306.ABSTRACTAcute kidney injury (AKI) is characterized by an abrupt decline of excretory kidney function. The incidence of AKI has increased in the past decades. Patients diagnosed with AKI often undergo diverse clinical trajectories, such as early or late recovery, relapses, and even a potential transition from AKI to chronic kidney disease (CKD). Although recent clinical studies have demonstrated a strong association between AKI and progression of CKD, our understanding of the complex relationship between AKI and CKD is still evolving. No cohort study has succe...
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Eun Sil Koh Sungjin Chung Source Type: research

Simultaneous Viability Assessment and Invasive Coronary Angiography Using a Therapeutic CT System in Chronic Myocardial Infarction Patients
CONCLUSION: The feasibility of the DE-MDCT viability assessment acquired simultaneously with conventional ICA was proven in patients with chronic MI using DE-CMR as the reference standard.PMID:38653564 | DOI:10.3349/ymj.2023.0208 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Seongmin Ha Yeonggul Jang Byoung Kwon Lee Youngtaek Hong Byeong-Keuk Kim Seil Park Sun Kook Yoo Hyuk-Jae Chang Source Type: research

Optimal Treatment Approaches to Intestinal Beh çet's Disease Complicated by Myelodysplastic Syndrome: The KASID and KSBD Multicenter Study
CONCLUSION: Patients with intestinal BD-MDS frequently have refractory diseases with high mortalities. HSCT can be an effective treatment modality for medically refractory patients with intestinal BD-MDS.PMID:38653565 | DOI:10.3349/ymj.2023.0321 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Jung-Bin Park So Jung Han Seung Bum Lee Dong Hyun Kim Jae Hee Cheon Sung Wook Hwang Byong Duk Ye Suk-Kyun Yang Soo Jung Park Sang Hyoung Park IBD Research Group of the Korean Association for the Study of Intestinal Diseases and the Korean Society for Behc Source Type: research

Safety of Biologics and Small Molecules for Inflammatory Bowel Diseases in Organ Transplant Recipients
CONCLUSION: The use of biologics or small molecules for patients with IBD who received organ transplants did not show a significant difference in safety outcomes. However, the possibility of severe infections must be considered.PMID:38653566 | DOI:10.3349/ymj.2023.0361 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Ga Hee Kim Minjun Kim Kyuwon Kim Jung-Bin Park Ji Eun Baek June Hwa Bae Seung Wook Hong Sung Wook Hwang Dong-Hoon Yang Byong Duk Ye Jeong-Sik Byeon Seung-Jae Myung Suk-Kyun Yang Sang Hyoung Park Source Type: research

Diffusion- and Perfusion-Weighted MRI Radiomics for Survival Prediction in Patients with Lower-Grade Gliomas
CONCLUSION: Adding diffusion- and perfusion-weighted MRI radiomics to clinical features improved survival prediction in lower-grade glioma.PMID:38653567 | DOI:10.3349/ymj.2023.0323 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Chae Jung Park Sooyon Kim Kyunghwa Han Sung Soo Ahn Dain Kim Yae Won Park Jong Hee Chang Se Hoon Kim Seung-Koo Lee Source Type: research

Prediction of High-Risk Neuroblastoma Among Neuroblastic Tumors Using Radiomics Features Derived from Magnetic Resonance Imaging: A Pilot Study
CONCLUSION: An MRI-based radiomics model can help predict high-risk neuroblastoma among neuroblastic tumors.PMID:38653568 | DOI:10.3349/ymj.2023.0192 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Jisoo Kim Young Hun Choi Haesung Yoon Hyun Ji Lim Jung Woo Han Mi-Jung Lee Source Type: research

Interrupting Effect of Social Distancing on Ischemic Heart Disease, Asthma, Stroke, and Suicide Attempt Patients by PM < sub > 2.5 < /sub > Exposure
CONCLUSION: While the interrupting effect of SD was not as pronounced as anticipated, this study did validate the effectiveness of SD in modifying health behaviors and minimizing avoidable visits to EDs in addition to curtailing the occurrence of infectious diseases.PMID:38653569 | DOI:10.3349/ymj.2023.0135 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Minseo Choi Mia Son Sanghyuk Bae Whanhee Lee Kyung-Nam Kim Jung K Hyun Source Type: research

Ssangcheon, Life of Lee Young-Choon (1903-1980)
Yonsei Med J. 2024 Apr;65(4):189-193. doi: 10.3349/ymj.2023.0445.NO ABSTRACTPMID:38515355 | PMC:PMC10973556 | DOI:10.3349/ymj.2023.0445 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Kang-Hyu Lee Joo-Min Lee Soon-Jae Yoon Chang-Seop Lee Source Type: research

Immune Cell-Mediated Autoimmune Responses in Severe Asthma
Yonsei Med J. 2024 Apr;65(4):194-201. doi: 10.3349/ymj.2023.0432.ABSTRACTSevere asthma (SA) has heterogeneous inflammatory phenotypes characterized by persistent airway inflammation (eosinophilic and/or neutrophilic inflammation) and remodeling. Various immune cells (eosinophils, neutrophils, and macrophages) become more activated and release inflammatory mediators and extracellular traps, damaging the protective barrier of airway epithelial cells and further activating other immune and structural cells. These cells play a role in autoimmune responses in asthmatic airways, where the adaptive immune system generates autoant...
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Thi Bich Tra Cao Quang Luu Quoc Jae-Hyuk Jang Hae-Sim Park Source Type: research

Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection
CONCLUSION: The presence of SARS-CoV-2 spike protein as well as altered inflammatory and apoptotic processes may indicate the presence of placental disturbance in third-trimester maternal COVID-19 infection. The lack of correlation between placental disruption and maternal severity status suggests the need for more research to understand the infection process and any potential long-term impacts on all offsprings born to COVID-19-infected pregnant women.PMID:38515357 | PMC:PMC10973560 | DOI:10.3349/ymj.2023.0309 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Manggala Pasca Wardhana Kuntaman Kuntaman Budi Utomo Rozi Aditya Aryananda Salsabila Nabilah Rifdah Ifan Ali Wafa Almira Aulia Shahnaz Dahlia Ningrum Nareswari Imanadha Cininta Grace Ariani Jan Mm Van Lith Erry Gumilar Dachlan Source Type: research

Application of Data Mining Technology in the Screening for Gallbladder Stones: A Cross-Sectional Retrospective Study of Chinese Adults
CONCLUSION: The results of this study showed that MLP and J48 algorithms are effective at screening individuals for the risk of GS. The key attributes of data mining can further promote the prevention of GS through targeted community intervention, improve the outcome of GS, and reduce the burden on the medical system.PMID:38515358 | PMC:PMC10973557 | DOI:10.3349/ymj.2023.0246 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Shuang Wang Chenhui Bao Dongmei Pei Source Type: research

Effect of Dietary Habits on Alzheimer's Disease Progression
CONCLUSION: Eating a balanced diet and reducing salt intake were associated with a slower decline in dementia severity, cognition, and behavioral alterations in patients with ADD.PMID:38515359 | PMC:PMC10973553 | DOI:10.3349/ymj.2023.0119 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: So Hyun Ahn Jee Hyang Jeong Kyung Won Park Eun-Joo Kim Soo Jin Yoon Bora Yoon Jae-Won Jang Yangki Minn Seong Hye Choi Source Type: research

Physical Activity-Induced Modification of the Association of Long-Term Air Pollution Exposure with the Risk of Depression in Older Adults
CONCLUSION: We suggest that older adults who vigorously exercise outdoors may be susceptible to air pollution-related depression.PMID:38515360 | PMC:PMC10973559 | DOI:10.3349/ymj.2023.0292 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Woongbi Park Heeseon Jang Juyeon Ko Jungwoo Sohn Young Noh Sun-Young Kim Sang-Baek Koh Changsoo Kim Jaelim Cho Source Type: research

Trend in the Incidence of Severe Partial Edentulism among Adults Using the Korean National Health Insurance Service Claim Data, 2014-2018
CONCLUSION: The study showed that the incidence trend of SPE increased and decreased from 2014 to 2018. This result would be able to aid in the planning of public oral health, and may also serve as fundamental data for verifying the impact of the public oral health policies implemented.PMID:38515361 | PMC:PMC10973558 | DOI:10.3349/ymj.2023.0380 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Hyeonjeong Go Hoi-In Jung Song Vogue Ahn Jeonghoon Ahn Hosung Shin Atsuo Amano Youn-Hee Choi Source Type: research

The First Case of a Korean Patient with a Mutation-Confirmed Tumor Necrosis Factor Receptor-Associated Periodic Syndrome
Yonsei Med J. 2024 Apr;65(4):241-245. doi: 10.3349/ymj.2023.0366.ABSTRACTTumor necrosis factor receptor-associated periodic syndrome (TRAPS, OMIM: #142680) is a rare autoinflammatory disease (AID) with recurrent febrile episodes. To our knowledge, we report herein the first case of a patient with TRAPS in South Korea whose symptoms included fever, arthralgia, abdominal pain, rash, myalgia, cough, and lymphadenopathy. A pathogenic de novo mutation, c.175T>C (p.Cys59Arg), in the tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) gene, was confirmed by gene sequencing. The patient has been with tocilizumab (an...
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Seok-Jin Lee Jee Yeon Baek Ji Young Lee Ji-Man Kang Jong Gyun Ahn Source Type: research