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Natural Orifices Transluminal Endoscopic Surgery (NOTES) in Germany: Summary of the Working Group Reports of the "D-NOTES Meeting 2009"Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The D-NOTES-group met in June 2009 for an evaluation of ongoing preclinical and clinical activities in natural orifice endoscopic surgery and the further coordination of research in Germany. Different working groups with various topics were formed. Consensus statements among various participants with different scientific and medical background were initiated. In summary, important topics were handled such as the correct handling of bacterial contamination and related complications, the question of the ideal entry point and a secure closure, interdisciplinary cooperation, and matters related to training and education. F...
Source: Zeitschrift fur Gastroenterologie - November 2, 2009 Category: Gastroenterology Authors: Meining A, Kähler G, Delius SV, Bueß G, Schneider A, Hochberger J, Wilhelm D, Kübler H, Kranzfelder M, Bajbouj M, Fuchs KH, Gillen S, Feußner H Tags: Z Gastroenterol Source Type: journals

[In Process Citation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19809953 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Simon B Tags: Z Gastroenterol Source Type: journals

[Are there gender-related differences in the therapeutic management of patients suffering from inflammatory bowel disease? Subgroup analysis of a prospective multicentre online-based trial]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study discloses the gender-specific differences in the therapeutic management of IBD patients in a congested urban area in Germany. Further studies are required to confirm the tendencies detected. PMID: 19809954 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Blumenstein I, Bock H, Zosel C, Dignass AU, Hartmann F, Zeuzem S, Stein JM, Schroeder O Tags: Z Gastroenterol Source Type: journals

[Colon cancer risk in persons at familial or hereditary risk aged < 55 years]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Persons aged 40 to 45 years with a familial risk constellation show a risk for colorectal cancer that equals the risk of 55- to 59-year-old persons from the general population. Therefore, the legal right for screening colonoscopy should be extended to the persons at risk aged 40 to 45 years. Persons suspected for hereditary risk should have a genetic counselling and, in case of germ mutation, a colonoscopic surveillance according to the actual guidelines. PMID: 19809955 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Waldmann A, Raspe H, Katalinic A Tags: Z Gastroenterol Source Type: journals

[The first case of anisakiasis acquired in Austria]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 67-year-old male patient with a gastric infestation of anisakiasis. The patient was on proton pump inhibitor which migh have caused the localisation of the infestation. The anisakis was an accidental endoscopic finding in a patient for control of an H. p.-positive gastric ulcer. Otherwise the patient was free of pain. The helminth (larva III) was endoscopically extracted. Thereafter, the patient remained in good health. Anisakis serology as well as repeated differential blood counts were without finding. The uneventful medical history and the normal blood findings indicate that our patient had a very early s...
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Kapral C, Haditsch M, Wewalka F, Schatzlmayr W, Lenz K, Auer H Tags: Z Gastroenterol Source Type: journals

Primary actinomycosis of the liver mimicking malignancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 71-year old women presented with fever, a significant loss of body weight and abdominal pain in the upper right quadrant since approximately six months. Abdominal ultrasonography and magnetic resonance imaging (MRI) showed an irregularly shaped, inhomogeneous and hypointense lesion of the right liver lobe (6 x 8 cm in segment 7 and 8) with multiple satellite lesions. Irregular shape, hypovascular presentation during gadolinium enhancement, hypointensity in T 1-weighted images and dilation of peripheral bile ducts were suggestive for cholangiocarcinoma or metastasis. However, histological investigations revealed a rar...
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Lange CM, Hofmann WP, Kriener S, Jacobi V, Welsch C, Just-Nuebling G, Zeuzem S Tags: Z Gastroenterol Source Type: journals

[Reflux disease and Barrett's oesophagus - are there gender-specific differences?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Studies of the prevalence of gastroesophageal reflux disease (GERD) have reported that male gender is an independent risk factor especially for erosive reflux disease (ERD). Non erosive GERD (NERD) is more common in females. The rate of prevalence and severity of reflux symptoms increase in females with age, while among men it peaked between 50 and 70 years and thereafter declined. The gender effect may be caused by differences in parietal cell mass between males and females. Barrett's esophagus is a major complication of gastroesophageal reflux disease and is associated with 30-125 times increased risk of developing c...
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Endlicher E, Gelbmann CM, Messmann H Tags: Z Gastroenterol Source Type: journals

[Inflammatory bowel disease and pregnancy]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Inflammatory bowel disease (IBD) affects mainly young people who are often in the process of family planning. Insecurity of patients and their primary physicians concerning the disease course and the appropriate medication is often followed by a decision against the pregnancy. With this overview these central issues will be discussed and practical guidelines will be provided, thus encouraging both sides, that IBD and pregnancy is compatible. PMID: 19809959 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 30, 2009 Category: Gastroenterology Authors: Siegmund B, Zeitz M Tags: Z Gastroenterol Source Type: journals

Acute liver failure in a metropolitan area in Germany: a retrospective study (2002 - 2008).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In providing first data on current ALF etiologies Germany, this study reveals that drug toxicity - in particular due to acetaminophen - has replaced viral hepatitis as the most single frequent cause of ALF in a densely populated urban area; this correlates with similar findings in the USA, the UK and Scandinavia. Lower body mass indices and elevated cholestatic enzyme levels had statistically significant prognostic power. PMID: 19750427 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Canbay A, Jochum C, Bechmann LP, Festag S, Gieseler RK, Yüksel Z, Lütkes P, Saner FH, Paul A, Gerken G Tags: Z Gastroenterol Source Type: journals

An observational real-time study to analyze junior physicians' working hours in the field of gastroenterology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This is the first real time analysis on how hospital gastroenterologists spend their working hours. Some of the problems with work routine reported by the doctors themselves were partly confirmed. With regard to the study results a rearrangement of job tasks coupled with technological solutions may prove helpful in reducing the burden on gastroenterologists and thereby improving the quality of medical care. PMID: 19750428 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Mache S, Bernburg M, Scutaru C, Quarcoo D, Welte T, Klapp BF, Groneberg DA Tags: Z Gastroenterol Source Type: journals

Unusual right upper quadrant Stump Appendicitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an unusual case of right upper quadrant stump appendicitis after previous operation for intussusception with incidental appendectomy. Abdominal computed tomographic scan is more efficient to make an early diagnosis of stump appendicitis to prevent further complications and prolonged hospitalization. PMID: 19750429 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Lin CT, Kuo SM, Wu CC, Jao SW Tags: Z Gastroenterol Source Type: journals

Penile and scrotal swelling in Crohn's disease: a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Penile and scrotal swelling considered as metastatic Crohn's disease is described in a 23 years-old-man. Clinical features and therapeutic options of this rare manifeatation are reviewed. PMID: 19750430 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Kaess H, Nitsche U Tags: Z Gastroenterol Source Type: journals

[Palliative care in gastroenterology: why do we need it and how do we qualify?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The rapid scientific progress in the past years has evoked debates about ethical limitations of technical innovations. Especially, high-end medicine for patients at the end of life gets in the focus of criticism whereas the idea of palliative care gains more importance. Gastroenterologists are an important partner in the setting of palliative care since many malignant tumors are found in the GI-tract; furthermore, about 80 % of all patients with advanced progressive illnesses being in a palliative care situation suffer from gastrointestinal symptoms. Vice versa the importance of palliative care in gastroenterology is i...
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Domagk D, Lenz P, Pott G Tags: Z Gastroenterol Source Type: journals

[Performance and interpretation of esophageal manometry: recommendations of the German societies for neurogastroenterology and motility (DGNM), for digestive and metabolic diseases (DGVS) and for general and visceral surgery (DGAV)]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Esophageal manometry examines the pressure profiles of the tubular esophagus and of the esophageal sphincters during resting conditions and in response to swallowing. It is regarded as the reference method for detection of esophageal motility disturbances but, up to date, performance of the procedure is not standardized among centers. This review depicts the recommendations of the German Societies for Neurogastroenterology and Motility, for Digestive and Metabolic Disturbances and for General and Visceral Surgery on indications, performance and analysis of conventional esophageal manometry. In addition to concise recom...
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Keller J, van der Voort I, Pehl C, Nicolaus M, Schirra J, Fox M, Fuchs K, Storr M Tags: Z Gastroenterol Source Type: journals

[Summary of the annual meeting of the German Society for Neurogastroenterology and Motility]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The annual meeting of the German Society for Neurogastroenterology and Motility was held at Castle Hohenkammer from 27 (th) to 29 (th) of March 2009. A "Young Investigator Meeting" took place on Friday communicating basics about scientific work. During the two-day main symposium, basic researchers and clinical scientists from Germany, but also from Europe, USA, Australia and Egypt presented their results on studies of the function of the enteric nerve system, gastrointestinal motility, and functional disturbances of the GI tract. Basic researchers as well as clinical scientists discussed the study results. Both days in...
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Pehl C, Andresen V Tags: Z Gastroenterol Source Type: journals

[Hyperglycemia: a risk factor for gastric cancer development?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19750434 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - August 31, 2009 Category: Gastroenterology Authors: Lippert E, Endlicher E Tags: Z Gastroenterol Source Type: journals

Sonographic signs of amyloidosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION: Typical sonographic signs of amyloidosis could be found in the heart, bowel wall, liver, spleen, gallbladder and thyroid and were illustrated as pictorial assays. PMID: 19662584 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Barreiros AP, Otto G, Ignee A, Galle P, Dietrich CF Tags: Z Gastroenterol Source Type: journals

[Gastropexy supported single-step button gastrostomy - clinical results of a new technique for percutanous feeding tube implantation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: On the basis of our first experience we conclude that by combination of the three techniques, introducer PEG with gastropexy, Seldinger wire, and balloon-type button, a single-step button gastrostomy can be safely performed. PMID: 19662585 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Dormann AJ, Aymaz S, Malfertheiner P Tags: Z Gastroenterol Source Type: journals

Increased Duodeno-Gastro-Esophageal Reflux (DGER) in symptomatic GERD patients with a history of cholecystectomy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: To conclude, our data provide first evidence of elevated DGER after CCE in patients with typical clinical symptoms of GERD using the Bilitec device. Both the frequency and the extent of DGER was significantly increased in the CCE-group. Prospective studies are urgently needed to elucidate the impact of CCE on DGER in patients with clinical symptoms of a reflux disease. PMID: 19662586 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Kunsch S, Neesse A, Huth J, Steinkamp M, Klaus J, Adler G, Gress TM, Ellenrieder V Tags: Z Gastroenterol Source Type: journals

[Lethal bleeding after accidental swallowing of a wooden meat skewer]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report about a 79-year-old patient who had swallowed a fragment of a wooden meat skewer which induced a perforation of the oesophagus and aorta walls. The patient was admitted to the hospital with signs of severe gastrointestinal bleeding. The emergency endoscopic examination confirmed the cause of the bleeding, but the patient died during the intervention from haemorrhagic shock. The forensic autopsy confirmed the clinical suspicion of an aorto-oesophageal fistula. PMID: 19662587 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Sauer BM, Staritz M, Perdekamp MG Tags: Z Gastroenterol Source Type: journals

Pregnancy-associated Sweet's syndrome in an acute episode of ulcerative colitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present and discuss a diagnostic algorithm and an overall therapeutic rationale for Sweet's syndrome. PMID: 19662588 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Best J, Dechene A, Esser S, Gerken G, Canbay A Tags: Z Gastroenterol Source Type: journals

[Matrix metalloproteinases in inflammatory bowel disease - from basic research to clinical significance]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article summarises the main activities of MMPs in IBD with emphasis on their pathophysiological relevance and potential clinical implications based on the expression and regulation patterns of these enzymes. PMID: 19662589 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Rath T, Roderfeld M, Graf J, Roeb E Tags: Z Gastroenterol Source Type: journals

[Reflux disease: PPI or operation?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19662590 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Schönfeld JV, Schröder J Tags: Z Gastroenterol Source Type: journals

[Barrett's without goblet cells: a finding with clinical relevance?!]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19662591 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - July 31, 2009 Category: Gastroenterology Authors: Vieth M Tags: Z Gastroenterol Source Type: journals

The effects of ageing on the colonic bacterial microflora in adults.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Conventional microbiological investigations of the fecal microbiota showed both bacteria-specific as well as a general pattern of ageing of the colonic microbiota, with the last decades (more than 60 years) demonstrating the most profound changes. It remains to be shown whether these changes reflect direct changes of the gut microbiota, the mucosal innate immunity, or indirect consequences of age-related altered nutrition. PMID: 19606407 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Enck P, Zimmermann K, Rusch K, Schwiertz A, Klosterhalfen S, Frick JS Tags: Z Gastroenterol Source Type: journals

[Costs of Crohn's disease in Germany from the perspective of the Statutory Health Insurance]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION: This is the first study to calculate costs due to CD (3767 euro/year) from the perspective of the Statutory Health Insurance in Germany. To illustrate the costs from the societal perspective, indirect costs need to be included in the calculation in future studies. PMID: 19606408 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Prenzler A, Mittendorf T, Conrad S, von der Schulenburg JM, Bokemeyer B Tags: Z Gastroenterol Source Type: journals

Successful treatment of fulminant hepatitis B during pregnancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We here report the use of lamivudine 100 mg daily in a young pregnant woman (24th week of gestation) with fulminant hepatic failure due to acute HBV infection. After initiation of oral lamivudine (100 mg/d), ALT levels rapidly decreased from 5046 U/L to normal values within five weeks. HBe seroconversion occured three weeks after treatment start, followed by HBs seroconversion within less than six months. A preterm female baby was delivered at gestational week 29 (weight 1000 gr) (five weeks after start of lamivudine). The infant received simultaneous active and passive HBV immunisation within 12 hours after delivery. ...
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Potthoff A, Rifai K, Wedemeyer H, Deterding K, Manns M, Strassburg C Tags: Z Gastroenterol Source Type: journals

Case report: extreme CgA elevation under PPI confounding assessment of adrenal mass.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Measurement of chromogranin A (CgA) level in blood can be used to monitor neuroendocrine tumours. However CgA level may also be elevated in several other endocrine and non-endocrine diseases. Here, we report on a patient with an incidental left-sided adrenal tumour and elevated CgA level. Adrenalectomy did not confirm clinically suspected diagnosis of pheochromocytoma. Postoperative follow-up was remarkable for a persistently elevated CgA level suspecting another neuroendocrine tumour which could not be detected despite extensive investigations. Finally, it was discovered that continuous proton-pump inhibitor administr...
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Wiedmann MW, Mössner J, Stumvoll M, Führer D Tags: Z Gastroenterol Source Type: journals

[Small bowel diverticula - unknown disease]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Diverticula of the small bowel are quite frequent (about 5 %), but being a differential diagnosis of abdominal complaints they may still be underdiagnosed. One reason for the low level of suspicion for a complication of small bowel diverticula might be that the small bowel was out of the gastroenterologists' focus until recently when small bowel endoscopy became available as a reliable and practical diagnostic tool. Diverticula of the jejunum and the ileum may lead to diverticulitis, abscess, obstruction, bleeding, and perforation. Small intestinal bacterial overgrowth syndrome due to small bowel diverticula is a commo...
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Albert JG, Lübbert C, Surow A, Zeuzem S Tags: Z Gastroenterol Source Type: journals

[Ultrasound guided interventions, part 1, diagnostic procedures]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ultrasound-guided punctures have been part of clinical routine for many years. Meanwhile the variety of biopsy needles has become huge, so that we can offer a special gadget for each indication and each organ. The results of investigations of the materials may help one to gain a general idea of the available possibilities and help to in the choice of the right one. In the special chapters about organs and tumour types one can find out which biopsy needles can achieve best results and guarantee the lowest possible level of complications. The path of access and possible injuries to important structures play an important ...
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Gottschalk U, Ignee A, Dietrich CF Tags: Z Gastroenterol Source Type: journals

[Detection of intraepithelial neoplasia in Barrett's Esophagus]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19606413 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Endlicher E, Zuber I Tags: Z Gastroenterol Source Type: journals

[Adherence to guidelines in the management of Barrett's Esophagus in the UK]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19606414 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - June 30, 2009 Category: Gastroenterology Authors: Troppmann M, Endlicher E Tags: Z Gastroenterol Source Type: journals

The State of Health Care and Health Care Paths in Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19533543 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Preiß JC, Blumenstein I, Zeuzem S, Zeitz M Tags: Z Gastroenterol Source Type: journals

The German Hep-Net Acute Hepatitis C Cohort: Impact of Viral and Host Factors on the Initial Presentation of Acute Hepatitis C Virus Infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In this large cohort of patients admitted for antiviral therapy, acute hepatitis C took a rather mild course of disease in the majority of patients. Disease severity was not associated with HCV genotype, viral load, age, sex and BMI. PMID: 19533544 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Deterding K, Wiegand J, Grüner N, Hahn A, Jäckel E, Jung MC, Buggisch P, Galle P, Berg T, Hinrichsen H, Potthoff A, Zeuzem S, Cornberg M, Manns M, Wedemeyer H Tags: Z Gastroenterol Source Type: journals

Evidence-Based and Consented Pathways for Patients with Inflammatory Bowel Diseases (IBD).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Crohn's disease and ulcerative colitis are diseases characterized by remission and relapse, an early age of onset and restrictions on activities and participation. IBD patients need a comprehensive, easily accessible and problem-oriented health care. This requires the integration and coordination of different health care sectors, medical and non-medical professionals, social and health care facilities and funding agencies. The pathways to guide patients through integrated health care were based on clinical considerations, interviews with patients and specialists, systematically searched evidence and results of a questi...
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Raspe H, Conrad S, Muche-Borowski C Tags: Z Gastroenterol Source Type: journals

Gastroenterology in Germany: Results of a Survey in Hospitals and Practices.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In future, the profile of gastroenterology in Germany - as in other countries - will change. New achievements such as capsule endoscopy, aero-scopes and advanced CT and MRI technology and others will become alternatives to conventional endoscopy. Additional emphasis in clinical and outpatient gastroenterology is shifted towards gastrointestinal oncology, dietetics, nutrition and metabolism and in the clinical setting onto infectious diseases, endocrinology/diabetology, intensive care medicine, emergency service and geriatric medicine. The German Confederation of Gastroenterology (BVGD) initiated two Germany-wide survey...
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Arnold R, Dathe K, Kühne D, Birkner B, Gerken G, Hermans ML, Lerch MM, Riemann JF, Schepp W Tags: Z Gastroenterol Source Type: journals

TNF-alpha Antibody Treatment in Refractory Collagenous Sprue: Report of a Case and Review of the Literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Collagenous sprue (CS) is a rare disease characterized by celiac type small bowel malabsorption that is resistant to gluten free diet (GFD) and is associated with a poor prognosis. Our aim was to assess the properties of the monoclonal TNF-alpha antibody infliximab in a patient with high-dose steroid refractory CS. A 27-year-old man developed watery diarrhea with weight loss and abdominal pain. Duodenal biopsies showed a subtotal villous atrophy with an extensive subepithelial layer of collagenous fibers. An apparent GFD did not reduce symptoms. High dose steroid treatment (75 mg prednisone) in combination with azathio...
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Schmidt C, Kasim E, Schlake W, Gerken G, Giese T, Stallmach A Tags: Z Gastroenterol Source Type: journals

Impressive Picture of a Melanosis Coli after Chronic Anthraquinone Laxative Use - Is there an Increased Risk for Colorectal Cancer?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 74-year-old female with an extreme picture of melanosis coli of the whole colon after chronic use of anthraquinone laxatives for the treatment of constipation over many decades. Endoscopic work-up revealed an impressive deep black pigmentation of the whole colon mucosa which could be verified by histopathology as a widespread lipofuscin granulation. In addition, various adenomas but no colorectal carcinoma could be detected. The term melanosis coli describes a brown or black pigmentation of the colonic mucosa. Induction of melanosis coli by anthraquinone laxatives and their derivatives can be regard...
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Abendroth A, Klein R, Schlaak J, Metz KA, Dobos GJ, Langhorst J Tags: Z Gastroenterol Source Type: journals

Early Barrett's Carcinoma/High Grade Intraepithelial Neoplasia (HG-IEN): Pro Endoscopic Treatment - Pro Surgical Treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Who may treat early Barrett's carcinoma of the oesophagus? The incidence of adenocarcinoma of the oesophagus developing within Barrett's mucosa has substantially risen in the past few years. Furthermore, treatment of preneoplastic lesions or early carcinoma is controversial. From an endoscopist's point of view high-grade intraepithelial neoplasia (HG-IEN) should be resected endoscopically rather than destroyed endoscopically while early Barrett's carcinoma should undergo endoscopic staging resection. Surgical resection is rarely necessary because lymph node metastases are rare and there is some morbidity and mortality ...
Source: Zeitschrift fur Gastroenterologie - May 31, 2009 Category: Gastroenterology Authors: Wehrmann T, Müller M, Arnold R, Sendler A Tags: Z Gastroenterol Source Type: journals

Presumed cryptogenic liver disease in Germany: High prevalence of autoantibody-negative autoimmune hepatitis, low prevalence of NASH, no evidence for occult viral etiology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Only one third of patients with initially presumed cryptogenic liver disease remained cryptogenic, while another third of patients could be identified as seronegative autoimmune hepatitis by the IAH-Score with obvious benefit from immunosuppressive therapy. PMID: 19418409 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Heringlake S, Schütte A, Flemming P, Schmiegel W, Manns MP, Tillmann HL Tags: Z Gastroenterol Source Type: journals

The impact of capsule endoscopy on surgical results in patients with obscure gastrointestinal bleeding.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: CE offers a high impact on the surgical results in patients with OGIB. Through our CE examinations the correct localization of the bleeding sources always provided a reasonable support to perform an optimal small bowel resection. PMID: 19418410 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Kovács M, Pák P, Pák G, Oláh A, Rácz I Tags: Z Gastroenterol Source Type: journals

Segmental haemorrhagic colitis under ciprofloxacin therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The segmental haemorrhagic colitis has been described as a particular form of antibiotics-associated colitis under penicillin therapy. A 34-year-old male presented in reduced general condition. He suffered from haematoschezia and abdominal pain. Due to a sinusitis maxillaris he had taken ciprofloxacin tablets (500 mg b. i. d.) for four days prior to the day of admission. Upon physical examination a slight general abdominal pain on palpation and some fresh blood at rectal digital examination were found. Apart from a slightly elevated CK level, all other routinely checked laboratory parameters were within normal ranges. ...
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Boesler B, Ott M, Menges M Tags: Z Gastroenterol Source Type: journals

[A 76-year-old male patient with iron deficiency anaemia - first experience with single-balloon enteroscopy]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a patient admitted to our hospital in order to to detect the reason for an iron deficiency anaemia. PMID: 19418412 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Huegle U, Aymaz S, Dormann AJ Tags: Z Gastroenterol Source Type: journals

[Hepatogenous diabetes - diagnostics and treatment]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Optimisation of diabetic metabolic conditions is not only important to avoid typical diabetic late complications but also cirrhosis-associated complications, e. g., gastrointestinal bleeding, hepatic encephalopathy or the occurrence of hepatocellular carcinoma. PMID: 19418413 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Gundling F, Schumm-Draeger PM, Schepp W Tags: Z Gastroenterol Source Type: journals

[Extrahepatic manifestations of chronic hepatitis C virus infection]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Current data suggest that HCV infection should be regarded as a systemic infectious disease with multiorgan involvement. More than 50 % of HCV-positive patients develop during the course of the disease at least one extrahepatic manifestation (EHM). The EHMs are often the first and only clinical signs of a chronic hepatitis C. Evidence of HCV infection should always be sought out in cases of unspecific chronic fatigue and/or rheumatic, haematological, endocrine or dermatological disorders. Key pathogenetic factors for the development of EHM are undisputably the HCV lymphotropism and cryoglobulinaemia. Nevertheless, the ...
Source: Zeitschrift fur Gastroenterologie - April 30, 2009 Category: Gastroenterology Authors: Puchner KP, Berg T Tags: Z Gastroenterol Source Type: journals

Small-bowel diagnosis in patients with familial adenomatous polyposis: comparison of push enteroscopy, capsule endoscopy, ileoscopy, and enteroclysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: FAP patients with duodenal adenomas particularly often have adenomas distal to the duodenum. CE is a safe and convenient method for evaluating the small bowel in these patients. EC is considerably inferior to the endoscopic procedures for evaluation of the small bowel and is therefore not suitable for the diagnosis of adenomas in FAP. PMID: 19358059 [PubMed - indexed for MEDLINE] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 31, 2009 Category: Gastroenterology Authors: Plum N, May A, Manner H, Ell C Tags: Z Gastroenterol Source Type: journals

A comparative scanning electron microscopic study of biliary and pancreatic stents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The occurrence of the tiny threads constitutes the central point in the clogging process in biliary and pancreatic stents. Inhibiting the formation of these threads or at least preventing adhesion to the inner stent surface might be the best option to improve stent patency. PMID: 19358060 [PubMed - indexed for MEDLINE] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 31, 2009 Category: Gastroenterology Authors: Weickert U, Zimmerling S, Eickhoff A, Riemann JF, Reiss G Tags: Z Gastroenterol Source Type: journals

[Catheter-free pH-metry using the Bravo capsule versus standard pH-metry in patients with non-erosive reflux disease (NERD)]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Prolonged pH-monitoring over a period longer than 24 hours did not improve the detection of acid reflux in patients with NERD. Thus, it appears that the Bravo pH-metry does not offer an advantage over standard pH-metry in the daily clinical practice. PMID: 19358061 [PubMed - indexed for MEDLINE] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 31, 2009 Category: Gastroenterology Authors: Mönkemüller K, Neumann H, Fry LC, Kolfenbach S, Malfertheiner P Tags: Z Gastroenterol Source Type: journals

Russell body gastritis associated with Helicobacter pylori infection in an HIV-positive patient: case report and review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In 1998 Tazawa and Tsutsumi described for the first time a case of Helicobacter pylori (HP)-related gastritis characterized by the presence of a conspicuous plasma cell infiltrate with Russell bodies, and coined the term Russell body gastritis (RBG). A 59-year-old HIV-positive man complaining of recurrent epigastric pain underwent an upper gastrointestinal endoscopy revealing in the stomach only hyperemia in the antral portion. Histology showed a moderate glandular atrophy associated with an expansion of the lamina propria due to an infiltration of monomorphous cells with eosinophilic cytoplasm inclusions and eccentric...
Source: Zeitschrift fur Gastroenterologie - March 31, 2009 Category: Gastroenterology Authors: Licci S, Sette P, Del Nonno F, Ciarletti S, Antinori A, Morelli L Tags: Z Gastroenterol Source Type: journals

[A 64-year-old woman with perianal bleeding, chronic diarrhea and severe fecal incontinence]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Unclear perianal bleeding may cause diagnostic and therapeutic difficulty, particularly when the bleeding source cannot be detected. In this case record we report on a 64-year-old woman with systemic sclerosis and incomplete CRES(T) syndrome diagnosed more than 10 years ago with no detectable teleangiectasia/angiodysplasia at that time. During the course of the disease the initially incomplete CRES(T) syndrome developed into a complete CREST syndrome with repeated bleeding from teleangiectatic/angiodysplastic lesions of the rectum, stomach/duodenum. In addition, chronic diarrhoea with malabsorption, bacterial overgrowt...
Source: Zeitschrift fur Gastroenterologie - March 31, 2009 Category: Gastroenterology Authors: Allgayer H, Dietrich CF Tags: Z Gastroenterol Source Type: journals