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[Antepartal maternal risks for shoulder dystocia. An analysis of 224 744 births spontanous and vaginal and after the 37th week of gestation born in Hessen (2002-2008)]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The pregnant woman should be informed about the statistically proved different maternal risk factors for a shoulder dystocia and a possible paresis of the Plexus brachialis in relation to the fetal birth weight. The sensitivity of 60% of the sonographic estimation of the fetal birth weight is to low and cannot be the only content of an information about this danger for the newborn. PMID: 19856238 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Berle P, Misselwitz B Tags: Z Geburtshilfe Neonatol Source Type: journals

[Paediatric brachial plexus injury--an interdisciplinary challenge to obstetricians, neonatologists and plexus surgeons]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brachial plexus injuries are an interdisciplinary challenge to obstetricians, neonatologists and plexus surgeons. The incidence of brachial plexus injuries is 1-4/1,000 live births, and the incidence of permanent lesions has been estimated to be 1/10,000 live births. Shoulder dystocia is associated with a 75-100-fold increase in plexus injuries. The antenatal (intrauterine) development of brachial plexus injuries is still a matter of controversial debate. The early recognition of antenatal risk factors of shoulder dystocia and its proper management by experienced obstetricians are mandatory; 90% of brachial plexus inju...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Bahm J, Rath W Tags: Z Geburtshilfe Neonatol Source Type: journals

[Prediction of shoulder dystocia--combining foetal weight estimation by ultrasound and maternal risk factors--a solution for the dilemma?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION: The accuracy of the estimation of foetal macrosomia has been improved by combining ultrasonography with prepartal maternal risk factors. PMID: 19856240 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Stein W, Delfy A, Schmidt S Tags: Z Geburtshilfe Neonatol Source Type: journals

[Nausea and vomiting as evolutionary mechanisms of the complex adaptation reaction to pregnancy]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our new and previously existing data support the idea that NVP has been selected for by evolution, as a functional adaptation to vulnerable early pregnancy, which benefits mother and child. This assumption is supported by the correlation of NVP with a better foetal prognosis, the cross-culturally high prevalence and a favorable relation of low biological costs versus high effects. The benefit of NVP could be realised by nutritional change, increased social support, more passive and careful behaviour, earlier recognition of pregnancy and a positive influence on foetal development. To understand the functionality...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Kohl S, Kainer F, Schiefenhövel W Tags: Z Geburtshilfe Neonatol Source Type: journals

The influence of smoking during pregnancy on fetal growth. Considering daily cigarette consumption and the SGA rate according to length of gestation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Our results allow the definition of groups of women who are at higher risk of SGA births. We show that especially older primiparous women (aged >or=31 years) who smoke >10 cigarettes a day are at increased risk of experiencing fetal growth restriction. PMID: 19856242 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Voigt M, Briese V, Jorch G, Henrich W, Schneider KT, Straube S Tags: Z Geburtshilfe Neonatol Source Type: journals

[Effectiveness and safety of atosiban vs. pulsatile administration of fenoterol in the treatment of preterm labour]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Atosiban was comparable in clinical effectiveness and was associated with fewer maternal and fetal adverse effects, so that fenoterol cannot be recommended. Completion of tocolytic therapy 12 hours after arrest of preterm labour is effective and associated with a short mean duration. PMID: 19856243 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Nonnenmacher A, Hopp H, Dudenhausen J Tags: Z Geburtshilfe Neonatol Source Type: journals

Massive labia minor hypertrophy following vulvar edema and abscess in pregnancy--case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A rare case is presented of vulvar edema and abscess with subsequent labia minor hypertrophy in a 26-year-old woman, which developed during two consecutive pregnancies with normal maternal and neonatal outcome. After a first pregnancy, the patient was initially treated conservatively, followed by incision of the abscess. After the second pregnancy, surgical correction of the hypertrophic labia minor was performed. The possible causes, complications and therapeutic options are discussed. PMID: 19856244 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Kulas T, Habek D, Hrgović Z Tags: Z Geburtshilfe Neonatol Source Type: journals

[Smith-Lemli-Opitz syndrome--case report, diagnostics and therapeutic options]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a female patient who was born at 37 weeks of gestation and was both small and light for gestational age who displayed typical signs of SLOS. After the diagnosis had been confirmed, a therapeutic approach with oral substitution of cholesterol and the administration of simvastatin was initiated. In spite of this strategy, the patient died at the age of 12 weeks from the disease. Based on the case presented, we review and discuss current diagnostic and therapeutic options for patients with SLOS. PMID: 19856245 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Oberthür A, Heller R, Vogel M, Körber F, Rahimi G, Hoopmann M, Emmel M, Roth B, Vierzig A Tags: Z Geburtshilfe Neonatol Source Type: journals

Antepartal Maternal Risks for Shoulder Dystocia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The pregnant woman should be informed about the statistically proved different maternal risk factors for a shoulder dystocia and a possible paresis of the Plexus brachialis in relation to the fetal birth weight. The sensitivity of 60% of the sonographic estimation of the fetal birth weight is to low and cannot be the only content of an information about this danger for the newborn. PMID: 19856238 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Berle P, Misselwitz B Tags: Z Geburtshilfe Neonatol Source Type: journals

Paediatric Brachial Plexus Injury - An Interdisciplinary Challenge to Obstetricians, Neonatologists and Plexus Surgeons.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brachial plexus injuries are an interdisciplinary challenge to obstetricians, neonatologists and plexus surgeons. The incidence of brachial plexus injuries is 1-4/1 000 live births, and the incidence of permanent lesions has been estimated to be 1/10 000 live births. Shoulder dystocia is associated with a 75-100-fold increase in plexus injuries. The antenatal (intrauterine) development of brachial plexus injuries is still a matter of controversial debate. The early recognition of antenatal risk factors of shoulder dystocia and its proper management by experienced obstetricians are mandatory; 90% of brachial plexus inju...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Bahm J, Rath W Tags: Z Geburtshilfe Neonatol Source Type: journals

Prediction of Shoulder Dystocia - Combining Foetal Weight Estimation by Ultrasound and Maternal Risk Factors - A Solution for the Dilemma?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION: The accuracy of the estimation of foetal macrosomia has been improved by combining ultrasonography with prepartal maternal risk factors. PMID: 19856240 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Stein W, Delfy A, Schmidt S Tags: Z Geburtshilfe Neonatol Source Type: journals

Nausea and Vomiting as Evolutionary Mechanisms of the Complex Adaptation Reaction to Pregnancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our new and previously existing data support the idea that NVP has been selected for by evolution, as a functional adaptation to vulnerable early pregnancy, which benefits mother and child. This assumption is supported by the correlation of NVP with a better foetal prognosis, the cross-culturally high prevalence and a favorable relation of low biological costs versus high effects. The benefit of NVP could be realised by nutritional change, increased social support, more passive and careful behaviour, earlier recognition of pregnancy and a positive influence on foetal development. To understand the functionality...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Kohl S, Kainer F, Schiefenhövel W Tags: Z Geburtshilfe Neonatol Source Type: journals

The Influence of Smoking during Pregnancy on Fetal Growth.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Our results allow the definition of groups of women who are at higher risk of SGA births. We show that especially older primiparous women (aged >/=31 years) who smoke >10 cigarettes a day are at increased risk of experiencing fetal growth restriction. PMID: 19856242 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Voigt M, Briese V, Jorch G, Henrich W, Schneider KT, Straube S Tags: Z Geburtshilfe Neonatol Source Type: journals

Effectiveness and Safety of Atosiban vs. Pulsatile Administration of Fenoterol in the Treatment of Preterm Labour.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Atosiban was comparable in clinical effectiveness and was associated with fewer maternal and fetal adverse effects, so that fenoterol cannot be recommended. Completion of tocolytic therapy 12 hours after arrest of preterm labour is effective and associated with a short mean duration. PMID: 19856243 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Nonnenmacher A, Hopp H, Dudenhausen J Tags: Z Geburtshilfe Neonatol Source Type: journals

Massive Labia Minor Hypertrophy Following Vulvar Edema and Abscess in Pregnancy - Case Report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A rare case is presented of vulvar edema and abscess with subsequent labia minor hypertrophy in a 26-year-old woman, which developed during two consecutive pregnancies with normal maternal and neonatal outcome. After a first pregnancy, the patient was initially treated conservatively, followed by incision of the abscess. After the second pregnancy, surgical correction of the hypertrophic labia minor was performed. The possible causes, complications and therapeutic options are discussed. PMID: 19856244 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Kulaš T, Habek D, Hrgović Z Tags: Z Geburtshilfe Neonatol Source Type: journals

Smith-Lemli-Opitz Syndrome - Case Report, Diagnostics and Therapeutic Options.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a female patient who was born at 37 weeks of gestation and was both small and light for gestational age who displayed typical signs of SLOS. After the diagnosis had been confirmed, a therapeutic approach with oral substitution of cholesterol and the administration of simvastatin was initiated. In spite of this strategy, the patient died at the age of 12 weeks from the disease. Based on the case presented, we review and discuss current diagnostic and therapeutic options for patients with SLOS. PMID: 19856245 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2009 Category: Perinatology & Neonatology Authors: Oberthür A, Heller R, Vogel M, Körber F, Rahimi G, Hoopmann M, Emmel M, Roth B, Vierzig A Tags: Z Geburtshilfe Neonatol Source Type: journals

[Sudden infant death syndrome (SIDS) caused by ATP-depletion following hyperventilation, tissue-hypoxia and hypermetabolism--a hypothesis]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was based on personal considerations and a selective online literature search. HYPOTHESIS: SIDS is the result of a frequently protracted ATP-depletion. DISCUSSION: Especially in combination, all risk factors for SIDS favour an ATP-deficiency by increasing ATP-catabolism and/or by diminishing ATP-synthesis. Prenatal chronic hypoxaemia and an insufficient supply with nutrients lead to low birth-weight, reduced adipose tissue, elevated haemoglobin F, increased sympathetic activity, hypermetabolism, and diminished hypoxia tolerance in the neonates. Because of reduced adipose tissue, more energy for thermogenesis is ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Deixler E Tags: Z Geburtshilfe Neonatol Source Type: journals

[Regionalisation of preterm births in county districts? Yes we can!]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: It was possible to diagnose preterm labour early enough for prenatal transfer. DISCUSSION: On the strength of past experience it may be assumed that the obstetrician's or institution's willingness to transfer mothers before delivery was the critical factor of the nearly complete regionalization. PMID: 19685405 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Pohlandt F, Artlich A, Freihorst A, Radlow U, Schädel G, Schneider A, Wölfel D Tags: Z Geburtshilfe Neonatol Source Type: journals

[Evaluation of maternal parameters as risk factors for premature birth (individual and combined effects)]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: We have shown that certain combinations of maternal parameters are associated with a high risk of premature deliveries (>10%). The risk table that we present here may assist in predicting premature delivery. PMID: 19685406 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Voigt M, Briese V, Pietzner V, Kirchengast S, Schneider KT, Straube S, Jorch G Tags: Z Geburtshilfe Neonatol Source Type: journals

[Careful planning of the decision-making process in neonatology: ethical orientation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Good decision making in neonatology must be context sensitive. General guidelines can be a helpful resource for carefully developing such a process. By taking the factors described in this paper into consideration, this task will be completed more efficiently. PMID: 19685407 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Wallner J Tags: Z Geburtshilfe Neonatol Source Type: journals

[Therapy for prenatally diagnosed lymphangioma--multimodal procedure and interdisciplinary challenge]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Extensive lymphatic malformations of the Head and Neck challenge treating physicians and affected families. Advancements of prenatal diagnostics and opportunities of peri- and postnatal interventions contribute to an improved survival chance and prognosis. Intensive interdisciplinary cooperation in specialised centers is of outstanding importance for an optimal care of these patients. PMID: 19685408 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Eivazi B, Sierra-Zuleta F, Ermisch S, Hellmeyer L, Schmidt S, Werner JA Tags: Z Geburtshilfe Neonatol Source Type: journals

[Gentamicin intoxication in a preterm infant]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a preterm (gestational age 32+2 weeks) infant with an accidental administration of a ten-fold dose of gentamicin. The baby was treated with a slight increase of fluid intake and monitoring of renal function and gentamicin levels, respectively. A rapid decrease of the gentamicin level (peak level 44.5 mg/L, extrapolated peak level 65 mg/L) was observed. Nephrotoxicity or ototoxicity did not occur. Because of the small number of described cases, a general recommendation for the management of gentamicin intoxication is not possible. The intensity of treatment depends on renal function and gentamicin leve...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Haase R, Lieser U, Butenhoff S, Merkel N Tags: Z Geburtshilfe Neonatol Source Type: journals

[Congress Report: "Recent advances in neonatology" , Würzburg, October 2nd-4th, 2008]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
[Congress Report: "Recent advances in neonatology" , Würzburg, October 2nd-4th, 2008] Z Geburtshilfe Neonatol. 2009 Aug;213(4):164-7 Authors: Kramer BW PMID: 19685410 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - July 31, 2009 Category: Perinatology & Neonatology Authors: Kramer BW Tags: Z Geburtshilfe Neonatol Source Type: journals

Foreword of the Editor-in-Chief.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19536705 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Schmidt S Tags: Z Geburtshilfe Neonatol Source Type: journals

Introduction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19536706 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Schneider H Tags: Z Geburtshilfe Neonatol Source Type: journals

The Role of the Placenta in Intrauterine Growth Restriction (IUGR).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Intrauterine growth restriction (IUGR) represents a reduction from the physiological growth rate. Fetal growth depends from the maternal supply of nutrients through the placenta into the umbilical circulation. Consequently, fetal growth restriction is associated with a reduced nutritional placental supply and this can result from a decrease in utero-placental blood flows as well as a reduced placental transport capacity. In IUGR, the placental supply of amino acids is significantly reduced independently from the severity of growth restriction and from the presence of hypoxia. Moreover, maternal-fetal gradients of gluco...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Cetin I, Antonazzo P Tags: Z Geburtshilfe Neonatol Source Type: journals

Die in-vitro Perfusion der menschlichen Plazenta mit Eryhtrozyten und Xanthine Oxidase als in vitro Simulation von Praeeklampsie.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The results suggest that perfusion with xanthine/xanthine oxidase and free hemoglobin induce changes in gene expression similar to what has been described for the preeclamptic placenta. PMID: 19536708 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Centlow M, Junus K, Nyström H, May K, Larsson I, Olsson MG, Akerström B, Sager R, Schneider H, Hansson SR Tags: Z Geburtshilfe Neonatol Source Type: journals

Studies of Placental Vasculogenesis: a Way to Understand Pregnancy Pathology?*Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Undisturbed development and growth of the fetus depends on an adequate vascular development in the fetomaternal unit. Several steps of vascular adaptation both on fetal and maternal side are necessary and involve uterine vasodilation and remodelling by extravillous trophoblast as well as vasculo- and angiogenesis within the placenta. Ubiquitous (e. g. VEGF, bFGF) as well as pregnancy specific (PlGF, hCG, IGF-II, AFP) angiogenic factors are involved. Consequences of abnormal vascular development have been associated with different pregnancy-related pathologies ranging from miscarriage to intrauterine growth restriction ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Herr F, Baal N, Zygmunt M Tags: Z Geburtshilfe Neonatol Source Type: journals

Angiogenic Factors and Their Role in Pathogenesis and Prediction of Preeclampsia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Angiogenic factors like placental growth factor (PlGF) and its anti-angiogenic antagonists soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng) are closely related to the pathogenesis of preeclampsia and intrauterine growth restriction (IUGR). The discovery and investigation of these angiogenic factors could characterize important pathogenetic mediators of preeclampsia or even the cause for placental dysfunctions. These anti-angiogenic proteins are dramatically elevated in maternal circulation weeks prior to the onset of the syndrome preeclampsia. Since it is known that altered maternal sFlt1, sEng an...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Stepan H, Jank A Tags: Z Geburtshilfe Neonatol Source Type: journals

Diagnosis and Treatment of Preeclampsia: Overview of International Recommendations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The new german guidelines for the treatment of hypertensive disorders in pregnancy have some important differentiations. The aim of the new guidelines is to avoid the early premature birth and to reduce the fetal and maternal morbidity and mortality. For the first time there ist the possibility and the recommendation for the prolongation of pregnancy. This means that the treatment of hypertensive disorders should start not before a blood pressure of >/=170/110 mmHg; thus the nutrition of the fetus will not be worsened and the worse perfusion of the placenta will be avoided. Further more the selection of antihyperten...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 31, 2009 Category: Perinatology & Neonatology Authors: Seck K, Fischer T Tags: Z Geburtshilfe Neonatol Source Type: journals

[Preterm and Term Infants with Acute Respiratory Distress Syndrome (ARDS): What is the Role of Surfactant Substitution?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Surfactant inactivation and dysfunction is also a hallmark in newborns with meconium aspiration syndrome (MAS), for which a beneficial effect of exogenous surfactant replacement. i.e., reduction of need for ECMO, could be shown. Although for the majority of the above-mentioned diseases process data from randomised, controlled trials are lacking, it is evident from clinical experience that surfactant replacement which counterbalances surfactant inactivation seems to improve oxygenation and lung function in many babies with ARDS without apparent negative side effects. Thus surfactant treatment seems to be justifi...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Wirbelauer J, Thomas W, Speer CP Tags: Z Geburtshilfe Neonatol Source Type: journals

[History of the German Antenatal Record ("Mutterpass") and its Need for Updating.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The history of the risk catalogue shows that its revision is essential to meet current health science requirements. Likewise, arguments for an evidence-based revision of the items of the risk catalogue are to be found in current literature. PMID: 19319792 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Schling S, Hillemanns P, Groß MM Tags: Z Geburtshilfe Neonatol Source Type: journals

[Increasing Clinical Applications of Stem Cells from Umbilical Cord Blood and Consequences for the Handling of this Biomaterial.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Umbilical cord blood (UCB) of a newborn contains stem cells with a remarkably high differentiation and regeneration potential. They are therefore useful for application in regenerative medicine. In this review current clinical applications are summarised and the necessity for the storage of UCB stem cells is derived and discussed. A Medline search for publications regarding clinical application of UCB stem cells was carried out and other data bases were reviewed. The transplantation of UCB stem cells, a special class of adult stem cells, has not only been established successfully in a variety of haematoblastoses but co...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Jacobs VR, Schneider KT Tags: Z Geburtshilfe Neonatol Source Type: journals

[Unilateral pulmonary agenesis, aplasia and dysplasia.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Unilateral pulmonary anomalies are rare events of unknown etiology and large clinical variability. Neonatal history does not allow for a reliable prognosis. Interdisciplinary mangament includes prenatal diagnostics and obstetrics, genetics, neonatology, pediatric cardiology and surgery as well as pediatric orthopedics. Neonatal history and long-term follow-up in three patients are presented here including a discussion of prenatal diagnostics and the embryo-genetic basics of lung development. In three term neonates the diagnoses of unilateral pulmonary agenesis, aplasia and dysplasia, respectively, were based on angiogr...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Dembinski J, Kroll M, Lewin M, Winkler P Tags: Z Geburtshilfe Neonatol Source Type: journals

[Neonatal seizures caused by lamotrigin withdrawal?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report about a 3-day-old full-term newborn who suffered from series of tonic-clonic and myoclonic seizures. His mother was treated with lamotrigin for epilepsy. It is worthy of note that the drug level of the neonate had already decreas-ed to 37% of the basic level of his mother. At the same time, there was a catabolic metabolic situation and a mild hyponatriaemia. We believe that the neonatal seizures were caused by lamotrigin withdrawal. PMID: 19319795 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Vieker S, Thiel M, Längler A Tags: Z Geburtshilfe Neonatol Source Type: journals

[Biventricular hypertrophic non-obstructive cardiomyopathy as a symptom of transient myeloproliferative disorder in a newborn with down syndrome.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report about a male, term newborn [birth weight 2 810 g (P10), length 49 cm (P30), head circumferance 35 cm (P50), APGAR 7/8/10] with hydrops fetalis. In the follow-up examination a pericardial effusion and increasing biventricular hypertrophic cardiomyopathy were obvious. A chemotherapy with cytarabine was initiated for five days. In further examinations cardiac recovery was observed. To the best of our knowledge this is the first case report of a term newborn with TMD and biventricular hypertrophic cardiomyopathy. PMID: 19319796 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - March 29, 2009 Category: Perinatology & Neonatology Authors: Wacker A, Scheel-Walter HG, Neunhoeffer F Tags: Z Geburtshilfe Neonatol Source Type: journals

[Classic maternal phenylketonuria and sonographic evidence of fetal trisomy 21: first description.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Phenylketonuria is the best known pathology of amino acid metabolism. Presented here is the case of a 23-year-old prima gravida with phenylketonuria since birth. After delivery, her child was diagnosed with free trisomy 21. Abnormal sonographic signs such as bilateral hydrothorax, polyhydramnion, and short femura under the 10th percentile could be demonstrated in the ultrasound scan at 33weeks of gestation. Regularly measured maternal phenylalanine levels during the complete pregnancy as well as preconceptionally were always under the embryopathic cutoff point of 1 200 micromoles/L (20 mg/L). An association seems unlik...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Lehnen H, Vinke M, Schwennicke C, Pascheberg U Tags: Z Geburtshilfe Neonatol Source Type: journals

[Pulse Oximetry as an Additive Procedure in Modern Fetal Assessment during Labour.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Fetal pulse oximetry saturation rates can be another helpful marker for fetal well-being in a modern labour ward. Further studies are required to verify whether fetal pulse oximetry saturation rates can improve the specificity of CTG for fetal acidosis. PMID: 19259899 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Schiermeier S, Hatzmann H, Reinhard J Tags: Z Geburtshilfe Neonatol Source Type: journals

[How Satisfied are Women with Maternity Care in Hospital?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Clinical expertise, emotional support and successful communication are the key indicators for quality in maternity care as viewed by postnatal women. These skills need further development if women's satisfaction as well as their willingness to recommend the maternity hospital is to be improved. PMID: 19259900 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Stahl K Tags: Z Geburtshilfe Neonatol Source Type: journals

[Long-term Tococlysis with Beta-2-mimetics - A Retrospective Analysis from One Centre.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The poor prognosis of extremely preterm infants improves rapidly with increasing gestational age, therefore long-term tocolysis should be considered as a therapeutic option in the case of an imminent birth. PMID: 19259901 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Stein W, Jahns B, Hawighorst T, Emons G Tags: Z Geburtshilfe Neonatol Source Type: journals

[Changes in Resistance of the Umbilical Artery, Foetal Movements and Short Time Variation through Clinical Hypnosis - Preliminary Results.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Preliminary results showed that blood flow of the umbilical artery can be improved by hypnosis. Further clinical studies are required to verify this hypothesis. The subjective impression of participants that foetal movements increase at the beginning of the trance seems to be correct. PMID: 19259902 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Reinhard J, Hüsken-Janßen H, Hatzmann H, Schiermeier S Tags: Z Geburtshilfe Neonatol Source Type: journals

[Changes in MR Images in Pre-Eclampsia and Eclampsia.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: These cerebral lesions could be classified as posterior reversible encephalopathy syndrome (PRES) or as reversible leukoencephalopathy syndrome (PLES). Thus, MRI supports differential diagnosis regarding non pregnancy-related cerebral disease and can be helpful for therapy planning in cases of pre-eclampsia. PMID: 19259903 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - February 1, 2009 Category: Perinatology & Neonatology Authors: Hellmeyer L, Iwinska-Zelder J, Gerken L, Kühnert M, Schmidt S Tags: Z Geburtshilfe Neonatol Source Type: journals

Obesity and pregnancy - a risk profile.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Obesity during pregnancy is associated with a range of maternal and fetal adverse outcomes. Pregnancy in obese women therefore calls for close monitoring and careful planning of delivery. Pre-conceptional weight reduction should be considered. PMID: 19085735 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Voigt M, Straube S, Zygmunt M, Krafczyk B, Schneider KT, Briese V Tags: Z Geburtshilfe Neonatol Source Type: journals

Risks of pregnancy and birth, birth presentation, and mode of delivery in relation to the age of primiparous women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Older primiparas have a higher proportion of previous miscarriages and terminations of pregnancy. They more commonly experience pathological presentations and also more frequently require Caesarean section. This means that a delayed first pregnancy - an increasingly common phenomenon in Germany - goes along with an increased likelihood of birth risks, Caesarean sections and peripartal interventions. Older primiparous women constitute a special risk group which may require a more intense level of care. PMID: 19085736 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Voigt M, Rochow N, Zygmunt M, Straube S, Schneider KT, Briese V Tags: Z Geburtshilfe Neonatol Source Type: journals

[Shoulder dystocia - risk factors and indicators.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: A BIP-thoracic diameter difference of greater than 14 mm is able to predict probable difficult courses of birth. This means that, from our point of view, ultrasonography close before delivery is an obligate necessity. PMID: 19085737 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Hitschold T, Grewe J Tags: Z Geburtshilfe Neonatol Source Type: journals

[Frequency of Caesarean Sections amongst Single-Foetus Births following Infertility Treatment: An Investigation by the Hessian Perinatal Registry (HEPE).]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The risks for Caesarean section are increased even for uncomplicated pregnancies when they follow infertility treatment. It can be assumed that, amongst other things, increased safety needs for couples and doctors together with more high-tech intensive care of pregnancies following infertility treatment will be required. In the event of a planned Caesarean section, comprehensive explanation of the risks involved will be necessary. PMID: 19085738 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Kolip P, Misselwitz B, Schmidt S Tags: Z Geburtshilfe Neonatol Source Type: journals

Caesarean Rate and Uterine Rupture: A 15-year Hospital-Based Observational Retrospective Study in Rural Tanzania.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DISCUSSION: The increasing Caesarean rates in rural sub-Saharan Africa might impose an additional hazard of increasing rates of uterine rupture without reducing the rates of maternal mortality and stillbirths. PMID: 19085739 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Stein W, Katundo I, Byengonzi B Tags: Z Geburtshilfe Neonatol Source Type: journals

[Foetal Electrocardiography (ECG) is an Alternative to Doppler Ultrasound Cardiotocogram (CTG) for Antenatal Assessment of Foetal Well-Being - Preliminary Results.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The foetal ECG monitor system may be a good alternative to Doppler ultrasound CTGs. With the perspective to analyse in a beat to beat manner foetal EKG heart rates, this new monitor system should be superior to Doppler ultrasound CTGs, however further larger studies are needed to confirm this hypothesis. PMID: 19085740 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - December 1, 2008 Category: Perinatology & Neonatology Authors: Reinhard J, Hatzmann H, Schiermeier S Tags: Z Geburtshilfe Neonatol Source Type: journals

[Leukemoid reaction in extremely immature preterm infants]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Extremely immature preterm infants rarely present with a leukocytosis exceeding 30,000/microL. The pathogenetic sequence leading to leukemoid reactions in non-malignant diseases remains to be elucidated. Potential triggers for leukemoid reactions in premature infants include prenatal corticosteroids, chorioamnionitis and funisitis or systemic infection. In the two-year period from 2006 to 2007 all infants with a gestational age of less than 26 weeks were screened for leukocytosis. Among our cases, one preterm infant presented with a leukocyte count of 229,300/microL at the age of 48 hours, lasting throughout the first ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2008 Category: Perinatology & Neonatology Authors: Wirbelauer J, Thomas W, Siauw C, Wössner R, Speer CP Tags: Z Geburtshilfe Neonatol Source Type: journals

[Surveillance of nosocomial infections among very low birth weight infants in NEO-KISS: from a voluntary system to a mandatory regulation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The inclusion of many new departments in NEO-KISS shows no influence to the reference data. And also the comparison of infection rates between new and old-departments shows no systematic discrepancy. It follows the unnecessary of separating the data from old-departments and new-departments and the appropriateness of the entire databank to generate the national reference data. PMID: 18956274 [PubMed - in process] (Source: Zeitschrift fur Geburtshilfe und Neonatologie)
Source: Zeitschrift fur Geburtshilfe und Neonatologie - October 1, 2008 Category: Perinatology & Neonatology Authors: Geffers C, Piening B, Schwab F, Gastmeier P Tags: Z Geburtshilfe Neonatol Source Type: journals