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Glioblastoma Invasion, Cathepsin B, and the Potential for Both to be Inhibited by Auranofin, an Old Anti-Rheumatoid Arthritis Drugemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1242756© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 5, 2010 Category: Neurosurgery Tags: Review Source Type: journals

Primary Optic Nerve Sheath Meningiomas: A Follow-up Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a follow-up study and treatment modalities based on our classification system.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 5, 2010 Category: Neurosurgery Tags: Original Article Source Type: journals

Poly-Axial Screw Removalemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe here an easy method for poly-axial screw removal. Leaving or placing a small piece of rod, attached firmly by a nut, tightens the head of the poly-axial screw. It can no longer move freely from the distal part of the screw and the screw can be removed by turning it counterclockwise with a big clamp or needle driver, which is available in almost every surgery set.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 5, 2010 Category: Neurosurgery Tags: Technical Note Source Type: journals

Depression and Anxiety in Patients Undergoing Herniated Disc Surgery: Relevant but Underresearched – A Systematic Reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article provides a systematic overview of the literature on the prevalence rates of depression and anxiety in patients undergoing surgery for a herniated disc.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 22, 2010 Category: Neurosurgery Tags: Review Source Type: journals

Lumbar Arachnoiditis and Thecaloscopy: Brief Review and Proposed Treatment Algorithmemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1243201AbstractThe term arachnoiditis describes the inflammation of the meninges and subarachnoid spaces. Lumbar arachnoiditis is characterized by obliterated nerve root sleeves and the adherence of nerve roots to each other in the proximity of the cauda equina, and may be secondary to infectious diseases or tumors, iatrogenic (subsequent to spinal surgery) or idiopathic. It is not very clearly defined epidemiologically or clinically, and various theories regarding its pathophysiology have been proposed; furthermore, its treatment is difficult because there is a lack of evidence-based d...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 14, 2010 Category: Neurosurgery Tags: Review Source Type: journals

Risk Management in the Treatment of Malignant Gliomas with BCNU Wafer Implantsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1242775AbstractImplantation of BCNU wafers (Gliadel) into the resection cavity has demonstrated a survival benefit for patients with newly diagnosed malignant gliomas. The follow-up of two phase III trails has further shown that the number of long-term survivors was significantly increased by BCNU wafer treatment. BCNU wafer implantation may be integrated into current multimodal first line strategies. In the setting of recurrent disease BCNU wafer implantation has also shown a survival benefit and now extends the treatment options in a patient population that typically has undergone ext...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 14, 2010 Category: Neurosurgery Tags: Review Source Type: journals

Malignant Brain Oedema after Radiosurgery of a Medium-sized Vestibular Schwannomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a patient with an unusual malignant brain oedema occurring after gamma knife radiosurgery of a medium-sized vestibular schwannoma.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 14, 2010 Category: Neurosurgery Tags: Case Report Source Type: journals

Surgical Technique and Validation of Outcome Assessment in Sagittal Synostosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1220714Abstract Aim of the study was to evaluate the outcome of children operated for sagittal synostosis, with special attention paid to the postoperative aesthetic result, as seen from the parents’ and the treating medical doctors’ perspective, and to assess the time point for operative correction.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 14, 2010 Category: Neurosurgery Tags: Original Article Source Type: journals

Giant Cell Tumor of the Frontal Bone in an 18-Month-Old Girl: A Case Reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1243200Abstract Giant cell tumors (GCT) are benign, but locally aggressive primary bone neoplasms, that frequently occur in the epiphyses of the long bones. Less than 1% of all GCTs primarily involve the skull where they are preferentially seen in the sphenoid and temporal bones. In the pediatric age group they are exceptionally rare.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - January 14, 2010 Category: Neurosurgery Tags: Case Report Source Type: journals

Implementation of a Critical Incident Reporting System in a Neurosurgical Departmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe the introduction of a mono-institutional critical incident reporting system in a neurosurgical department. Furthermore, we have developed a formula to assess possible counterstrategies.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - December 19, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Long-Term Follow-up of a Non-Infantile Desmoplastic Gangliogliomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1241180© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - December 19, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Isolated Lympho-histiocytic Inflammation of the Gasserian Ganglion Mimicking Trigeminal Schwannomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present an unusual case of a patient with trigeminal pain and hypesthesia suggesting trigeminal schwannoma, where histology demonstrated an inflammatory lesion of the Gasserian ganglion.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - December 8, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Fusiform Aneurysm of the Proximal Anterior Cerebral Artery (A1)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article presents an additional case treated by microsurgical trapping. The aim is to discuss the treatment of these aneurysms based on the aneurysm morphology and the anatomy of the ACA complex.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - December 8, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Extended Extra- and Intracerebral Ulceration and Brain Abscess Following Self-mutilation in an Auto-aggressive 51-year-old Woman: Case Reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present an extraordinary case of an auto-aggressive 51-year-old female suffering from a deeply ulcerated wound on the right frontal skull with consecutive brain abscess, caused manually with needles and forceps over a period of 8 months. The clinical course is presented together with a description of the conservative and surgical regimen and is illustrated with photographs and CT and MRI images.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - December 8, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Radiofrequency Neurotomy for Headache Stemming from the Zygapophysial Joints C2/3 and C3/4email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cen Eur NeurosurgDOI: 10.1055/s-0029-1224159Abstract Headaches are a major socio-economic problem, and reliable and effective treatments may have an important economic impact. While many studies have investigated neck pain stemming from the zygapophysial joint, there is little data on the specific problem of headache from the zygapophysial joint C3/4.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 28, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Endovascular Coiling in 131 Patients with Low Complication Rate Justifies Treating most Unruptured Intracranial Aneurysmsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present the results of endovascular coiling of 131 patients with UIAs from a high volume unit and a risk-benefit analysis based on patient and aneurysm characteristics.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 26, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Haemorrhage from a Radiosurgically Treated Arteriovenous Malformation after its Angiographically Proven Obliteration: a Case Reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present here a patient with an AVM repeatedly treated at our Leksell Gamma Knife unit with radiographically confirmed obliteration of the AVM which subsequently began bleeding. This case demonstrates the possibility of late complications in radiosurgically treated AVMs even after their demonstrable obliteration. Meticulous histological examination was performed, proving patency of the AVM nidus. The risk of haemorrhagic complications of radiosurgically removed AVMs despite angiographic proof of their obliteration is, in our view, a cogent argument for preferring surgical resection if the AVM is accessible and for prolon...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 26, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Contrast Enhancement and Histopathological Findings in Vestibular Schwannomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a case of a large vestibular schwannoma with heterogeneous contrast uptake on MRI. Using neuronavigation, histological samples were obtained during surgery from an area with homogeneous contrast uptake and from a central tumor portion without contrast enhancement on MRI. Intraoperative investigation found no evidence of necrotic tumor, and histopathological examination revealed an active tumor in both sections, with no central necrosis. This finding illustrates the surgical experience that “necrotic tumor areas” on MRI may not be consistent with intraoperative findings. Lack of contrast uptake in pre...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 21, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Formation of Two Consecutive Intrathecal Catheter Tip Granulomas within Nine Monthsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1202359AbstractThe formation of catheter tip granulomas is an increasingly observed serious complication of intrathecally administered medication. This complication, which is frequently associated with neurological disturbances, has previously been attributed to high dosages and high concentrations of intrathecal morphine. Much less commonly, intrathecal hydromorphone and intrathecal baclofen have also been associated with intrathecal granuloma formation. In the current case, we report a patient who developed her first catheter tip granuloma after 20 months of intrathecal morphine. Af...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 19, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Endoscopic Anatomy for Transnasal Transsphenoidal Pituitary Surgery in the Presence of a Persistent Trigeminal Arteryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 207-210DOI: 10.1055/s-0028-1093354Abstract Endoscopic procedures are becoming increasingly important for transnasal transsphenoidal approaches to the skull base and particularly for pituitary surgery. A persistent trigeminal artery (PTA) is rare. Its presence, if it goes unnoticed or if the surgeon is not aware of such a variant, may endanger the success of surgery.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 18, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Erratumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1243182© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  FREE: Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 12, 2009 Category: Neurosurgery Tags: Erratum Source Type: journals

Pulsatility of an Intracavernous Aneurysm Demonstrated by Dynamic 320-detector Row CTA at High Temporal Resolutionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe a patient with an intracavernous aneurysm in whom the area of increased aneurysm pulsatility as demonstrated by high-temporal resolution CTA was identical to the area of aneurysm growth on follow-up. A 35-year-old man presented with headaches and a sixth nerve palsy. CT including dynamic CTA demonstrated a pulsating intracavernous aneurysm. On follow-up one week later, the patient had developed hypesthesia in his V1 and V2 distribution and repeat imaging demonstrated aneurysm growth in the aneurysm part that demonstrated pulsatile movements on dynamic CTA. Stent-assisted coiling of the aneurysm was performed an...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 23, 2009 Category: Neurosurgery Tags: Technical Note Source Type: journals

Are there False-negative Results of Motor Evoked Potential Monitoring in Brain Surgery?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1225651Abstract The present study explores the causes of occasional postoperative pareses despite unchanged or fully recovered intraoperative motor evoked potentials (MEPs) in supratentorial brain surgeries.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Nonconvulsive Status Epilepticus as a Possible Cause of Coma in Neurosurgical Intensive Careemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1224168AbstractNonconvulsive status epilepticus (NCSE) can occur in comatose patients without clinical signs of seizure activity. We evaluated the occurrence of NCSE in patients who were admitted to our neurosurgical intensive care unit between 1998 and 2000. EEGs were obtained from 158 patients with head trauma, spontaneous bleeding or brain tumour. Patients with clinically apparent seizure activity or no electrophysiological signs of seizure activity were excluded from the study. Epileptiform activity was seen in 28 out of 158 patients. 11/28 of these patients had a Glasgow-Coma-Sca...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Effects of GYKI 52466 on Early Vasospasm in Ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1202357Abstract The pathogenesis and treatment of cerebral vasospasm (CV) after subarachnoid hemorrhage (SAH) remains a matter of discussion. The authors investigated the efficacy of GYKI 52466, a 2,3-benzodiazepine that is a selective and potent α-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) receptor antagonist, in a rat femoral artery vasospasm model.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Completely Ossifiying Pseudomeningocele, a Rare Complication after Spinal Surgeryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report the rare case of an ossified pseudomeningocele following laminectomy. The extradural pseudocyst has completely ossified without an overt communication to the subarachnoid space.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 23, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Decompressive Hemicraniectomy for Space-occupying Cerebral Infarctionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1216362AbstractThe development of a space-occupying hemispheric infarction occurs in a subset of patients with ischaemic cerebrovascular stroke. It is a life-threatening condition with a high mortality rate of up to 80% with medical therapy alone. Previous retrospective and uncontrolled case series have suggested that decompressive hemicraniectomy can significantly reduce mortality to 20–30% compared to conservative treatment. This evidence has now been confirmed by the data of prospective randomised studies. The data also indicate that the reduction of mortality is not accompan...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - October 22, 2009 Category: Neurosurgery Tags: Review Source Type: journals

Confocal Neurolasermicroscopy in Human Brain – Perspectives for Neurosurgery on a Cellular Levelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study we present confocal neurolasermicroscopy as a new method in neurosurgery.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - September 29, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Therapeutic Clues In Spinal Dural Arteriovenous Fistulas – A 30 Year Experience Of 156 Casesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1224195 Spinal dural arteriovenous fistulae (SDAVF) are rare but remain the most common type of spinal vascular malformations. Treatment options for SDAVF include endovascular embolization, microsurgical dissection or a combination of both. But the optimal treatment paradigm has yet to be defined and may well be an individualized interdisciplinary combinatorial approach.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - September 26, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Anterior Cervical Discectomy and Titanium Cage Fusion – 7-year Follow-upemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1220940Abstract The purpose of this study was to prospectively evaluate long-term results after anterior cervical discectomy and titanium cage fusion (ACDF) and titanium cage fusion. Special focus was on the adjacent levels.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - September 1, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Resolution of Trigeminal Neuralgia after Palliative Embolization of a Cerebellopontine Angle Arteriovenous Malformationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 161-163DOI: 10.1055/s-0029-1215567Abstract Trigeminal neuralgia (TN) is a syndrome with debilitating paroxysmal facial pain, one cause of which is thought to be vascular compression of the nerve root entry zone causing ephaptic transmission. Arteriovenous malformations (AVM) have been reported to cause TN, including AVMs in the cerebellopontine (CP) angle. These lesions have been successfully treated with endovascular coiling, ethylene-vinyl alcohol copolymer (Onyx) and surgery for decompression.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstrac...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Exophytic Intramedullary Mature Teratoma of the Conus Medullaris: Case Report and Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 154-160DOI: 10.1055/s-0028-1082062Abstract Intramedullary tumors affect a small but significant portion of patients with spinal tumors. Ependymomas and astrocytomas are the most common entities. The diagnosis of a mature teratoma is extremely rare, although not in the presence of associated developmental abnormalities. The medullary conus is the most common location. Such a case with caudal exophytic growth is presented here and the literature extensively reviewed.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zen...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Metastasis to Pituitary Adenoma: Case Report and Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a rare case of a metastasis to a pituitary adenoma and review 14 cases published in the literature to date. Metastases to pituitary adenomas most commonly present with rapidly progressing chiasm compression syndromes, headaches and oculomotor nerve palsies. The prognosis for this condition is poor. Metastases to pituitary adenomas have to be considered in the differential diagnosis of sellar tumors.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

First-line Stereotactic Treatment of Thalamic Abscesses: Report of Three Cases and Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report our experience in 3 consecutive cases of thalamic abscess, treated by stereotactic puncture as the first step, followed by histological analysis, external drainage and targeted intrathecal and systemic antibiotic therapy. Deep-seated abscesses seem to behave differently as they are associated with an increased risk of intraventricular rupture and antibiotic resistance, a fact which justifies a more aggressive and immediate surgical treatment. We review the literature on this topic in the last 20 years.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Review Source Type: journals

Perioperative Complication Rate of Lumbar Disc Microsurgery Depending on the Surgeon's Level of Trainingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 137-142DOI: 10.1055/s-0029-1216361Abstract Lumbar disc surgery is one of the procedures performed early in neurosurgical training. Agreement exists concerning the use of microsurgical techniques. With increasing surgical experience the clinical outcome should improve, partly because of a reduction in the complication rate. The aim of this study was to evaluate the correlation between patients’ immediate clinical outcome, the perioperative complication rate and the surgeons’ level of experience.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Assessment of Normal Perisellar Anatomy in 1.5 T T2-weighted MRI and Comparison with the Anatomic Criteria defining Cavernous Sinus Invasion of Pituitary Adenomasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 130-136DOI: 10.1055/s-0029-1216363Abstract The study aimed to evaluate the anatomical relations of sellar and perisellar structures with T2-weighted MRI and to apply criteria for cavernous sinus (CS) invasion by pituitary adenomas to normal sellar anatomy.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

The Hour-glass Model of Corpus Callosum Injuryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 125-129DOI: 10.1055/s-0029-1214384AbstractIn this retrospective study, the authors analyze the frequency, anatomical distribution and the clinical outcome of 44 patients after severe head injury, with and without lesions of the corpus callosum (CC). 44 patients with severe head injury (GCS<9 on admission), who were admitted to the intensive care unit of the Department of Neurosurgery after trauma, underwent early MR-tomography (T1, T2 and FLAIR sequences) in addition to CCT performed on admission. CC lesions were found in about 1/3 of patients with severe head injury. Posterior (splenium) l...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Apoptotic Proteins and Markers of Differentiation in Childhood Pineal Parenchymal Tumors: Relationships and Prognostic Valueemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 115-124DOI: 10.1055/s-0029-1202356AbstractPineal parenchymal tumors (PPTs) in children and adolescents are uncommon and more data on their biological activity and behavior are still needed. The aim of our study was to estimate the expression and prognostic value of some proteins regulating apoptosis and cell cycle as well as being markers of cellular differentiation in PPTs. Tumor specimens obtained from 27 patients who underwent surgical treatment for PPTs were evaluated in immuno-histochemical analysis. The expression of Bcl-2, Bax, p53, NSE (neuron specific enolase), GFAP (glial fibrillary ...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Neuroprotective Effect of Melatonin on Experimental Peripheral Nerve Injury: An Electron Microscopic and Biochemical Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 109-114DOI: 10.1055/s-0029-1220712Abstract Melatonin is an important antioxidant agent with a protective role in the prevention of oxidative stress. We designed an experimental study which focused on the potential neuroprotective effect of melatonin on peripheral nerve injury.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - August 23, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Spinal Neurosurgery with the Head-mounted “Varioscope” Microscopeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a preliminary report on the intra-operative use of a head-mounted microscope (“Varioscope” Leica HM500) in spinal neurosurgery. The Varioscope is a dynamic microscope mounted on a head-set. It weights 297 g and measures 73×120×63 mm (length×width×height). It offers an infinitely variable range of magnification from 3.6× to 7.2×. The working distance ranges from 300 to 600 mm. The field of view varies between 30–144 mm, depending on the selected enlargement factor and the working distance. In addition to the zoom function, the device offers a focus function (automat...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Technical Note Source Type: journals

Frontal Sinus Osteoma Complicated by Extended Intracranial Mucocele and Cerebral Abscess: Neurosurgical Strategy of a Rare Clinical Entityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report here on a second patient with combined frontal sinus osteoma, intracerebral mucocele as well as cerebral abscess. However, in our case, the diagnosis of cerebral abscess was reached prior to surgery, which allowed for a tailored treatment strategy with abscess puncture under neuronavigational guidance and, after 3 weeks of antibiotic therapy with documented abscess shrinkage, osteoma and mucocele resection as well as reconstruction of the eroded dura.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Cen...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Intracranial Trigeminal Nerve Metastasis of a Desmoplastic Neurotropic Melanoma: Case Reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 91-94DOI: 10.1055/s-0028-1082065Abstract Desmoplastic neurotropic mela-noma is a rare and highly malignant variant of melanoma. Solitary nervus trigeminus and Gasserian ganglion metastasis of a neurotropic melanoma has not been previously described in the literature.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

A Subarachnoid Haemorrhage Primarily Presenting as Terson's Syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a case of a subarachnoid haemorrhage due to a ruptured basilar artery aneurysm in a 61-year-old woman. She presented with visual deterioration as the only clinical sign, no previous episodes of headache were reported. Fundoscopy showed a bilateral vitreous haemorrhage. A consecutively performed cranial computer tomography demonstrated subarachnoid bleeding. Further diagnostics revealed a basilar artery aneurysm that was successfully treated with coil embolisation. As a scarring of the vitreous bodies developed, they had to be removed. The patient's eyesight improved gradually and no further complications occurre...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Intraventricular Textiloma with Granuloma Formation Following Third Ventricle Colloid Cyst Resection – A Case Reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report the neuroimaging evaluation, including computed tomography (CT), magnetic resonance imaging (MRI) and spectroscopy (H1-MRS), in a case of textiloma developing after the treatment of a third ventricle colloid cyst.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Intracranial Aneurysms in Childhood: Report of 8 Cases and Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 79-85DOI: 10.1055/s-0028-1093353Abstract Subarachnoid haemorrhage (SAH) due to ruptured cerebral aneurysms is a rare diagnosis in childhood and is believed to differ from that in adults with regard to sex, aneurysm size and location, clinical appearance as well as outcome, suggesting that aneurysms in childhood are a distinct entity.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Review Source Type: journals

Acute Subdural Hematoma in the Elderly; Clinical and CT Factors Influencing the Surgical Treatment Decisionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 73-78DOI: 10.1055/s-0029-1224096Abstract Acute subdural hematomas (aSDH) are severe traumatic brain injuries. Older patients have a higher mortality rate. In the present study the computed tomography (CT) and neurological deficits caused by aSDH were used as prognostic factors to define the outcome and surgical treatment indication in older patients.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Sinking Skin Flap Syndrome (SSFS) – Clinical Spectrum and Impact on Rehabilitationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 68-72DOI: 10.1055/s-0028-1093355Abstract“Sinking skin flap syndrome” (SSFS) is defined as a secondary neurological deterioration in the presence of a sinking skin flap in patients with large craniectomies. Although changes in cerebrospinal fluid (CSF) hydrodynamics, cerebral blood flow and brain metabolism have been described as partial aspects of the pathophysiology, a conclusive concept, integrating all contributing factors, is still lacking. Knowledge about the true incidence of this phenomenon is rare. This case series describes the clinical spectrum of SSFS. Since it is to be ...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

A Multimodal Concept in Patients after Severe Aneurysmal Subarachnoid Hemorrhage: Results of a Controlled Single Centre Prospective Randomized Multimodal Phase I/II Trial on Cerebral Vasospasmemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 61-67DOI: 10.1055/s-0028-1087214Abstract Recent publications suggest that a combination of head-shaking and cisternal irrigation might reduce symptomatic cerebral vasospasm after subarachnoid hemorrhage (SAH). The present clinical prospective randomized phase I/II study was initiated in order to analyze the prophylactic effect of intracisternal lysis in combination with kinetic treatment followed by intrathecal nimodipine lavage.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neurochirurgie - Centr...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - May 27, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

A Reminder of the Anatomy of the Recurrent Artery of Heubneremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl Neurochir 2009; 70: 36-38DOI: 10.1055/s-0028-1119379AbstractPrevious accounts of the recurrent artery of Heubner show serious inconsistencies concerning the origins, dimensions and numbers of the artery. In the present study, based on 54 (38 male, 16 female) human autopsy brains the common type of the recurrent artery of Heubner was present bilaterally in 46 cases (85.2%), while in 6 (11.1%) cases it was present only on one side (4 on the right, 2 on the left). Unilateral vessels were seen only in the male autopsy brains. The recurrent artery of Heubner could not be identified in 2 brains (3.7%). Multiple Heubner...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 20, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals

Use of Statins for the Treatment of Spontaneous Intracerebral Hemorrhage: Results of a Pilot Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0028-1082064Abstract Spontaneous intracerebral hemorrhage (ICH) represents the most fatal kind of stroke, and there is still no treatment available that improves the outcome. Statins are cholesterol reducers, and during the last few years many additional effects have been demonstrated that might be neuroprotective. We designed a pilot clinical study in order to evaluate whether the administration of statins is associated with a better outcome.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Zentralblatt fur Neur...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 6, 2009 Category: Neurosurgery Tags: Original Article Source Type: journals