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This page shows you the latest news and research items in this category.

Codeine Risky for Kids After Certain Surgeries, FDA Says
10 deaths, 3 overdoses reported following removal of tonsils or adenoids Source: HealthDay Related MedlinePlus Pages: Medicines and Children, Pain Relievers (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 21, 2013 Category: Consumer Health News Source Type: news

FDA Warns About Using Codeine After Tonsillectomy
Medicines that contain codeine should not be used for pain relief in kids after a tonsillectomy or adenoidectomy (surgery removing the tonsils or adenoids), because there is a chance of serious side effects or possible death, according to the U.S. Food and Drug Administration (FDA). A new boxed warning addressing the risk of codeine for post-surgery pain management in children will be added to medicines that contain codeine. A boxed warning is the FDA's highest warning level... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

Codeine After Tonsillectomy Dangerous, FDA Warns
Medicines that contain codeine should not be used for pain relief in kids after a tonsillectomy or adenoidectomy (surgery removing the tonsils or adenoids), because there is a chance of serious side effects or possible death, according to the U.S. Food and Drug Administration (FDA). A new boxed warning addressing the risk of codeine for post-surgery pain management in children will be added to medicines that contain codeine. A boxed warning is the FDA's highest warning level... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

FDA drug safety communication: Update of codeine use in children- new Boxed Warning and Contraindication on use after tonsillectomy and/or adenoidectomy
Source: FDA Area: News The FDA has notified the public about new actions being taken to address a known safety concern with codeine use in certain children after tonsillectomy and/or adenoidectomy In August, it had issued an alert, following reports of children who developed serious adverse effects or died after taking codeine for pain relief after these procedures for obstructive sleep apnoea syndrome. These children (aged two to five) had evidence of an inherited ability to convert codeine into life-threatening or fatal amounts of morphine in the body. All children had received doses of codeine that were with...
Source: NeLM - News - February 21, 2013 Category: Drugs & Pharmacology Source Type: news

FDA Warns About Codeine Following Tonsillectomy
(MedPage Today) -- Products that contain codeine should not be used for pain relief in children following tonsillectomy or adenoidectomy because of a possible risk of serious adverse events or death, the FDA said Wednesday. (Source: MedPage Today Pain Management)
Source: MedPage Today Pain Management - February 20, 2013 Category: Anesthesiology Source Type: news

Codeine Use in Certain Children After Tonsillectomy and/or Adenoidectomy: Drug Safety Communication - Risk of Rare, But Life-Threatening Adverse Events or Death
Audience: Pediatricians, Surgery, Consumer [UPDATED 02/20/2013] FDA notified the public about new actions being taken to address a known safety concern with codeine use in certain children after tonsillectomy and/or adenoidectomy (surgery to... (Source: Drugs.com - FDA MedWatch Alerts)
Source: Drugs.com - FDA MedWatch Alerts - February 20, 2013 Category: Drugs & Pharmacology Source Type: news

Comparison of two different adenoidectomy techniques with special emphasize on postoperative nasal mucociliary clearance rates: Coblation technique vs. cold curettage
Abstract: Objective: To compare the cold curettage and coblation techniques for pediatric adenoidectomy by means of intraoperative blood loss, operation time, and pre- and postoperative nasal mucociliary clearance rates.Methods: The study included 60 consecutive patients undergoing adenoidectomy operation upon the diagnosis of adenoid hypertrophy ranging in age 4–8 years (mean age: 5.82±1.25 years). Two groups consist of 30 patients. The two different adenoidectomy techniques were compared by means of intraoperative blood loss, operation duration, preoperative and postoperative nasal mucociliary clearance rate (NMCR) va...
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Mahmut Özkiriş, Seyhan Karaçavuş, Zeliha Kapusuz, Levent Saydam Tags: Research papers Source Type: research

The TIMP-1 expression in germinal centers of hypertrophied adenoids in children
Conclusion: It is difficult to interpret our results. Our findings did not demonstrate changes in TIMP-1 expression according to age. This may indicate that the processes of hyperplasia, hypertrophy and atrophy of adenoid are not influenced by age and support our thesis that adenoid involution is rather the effect of changes in the number of lymphoid follicles that changes in them. However there is a need for further observational studies of TIMPs and MMPs in adenoid tissue. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Marcin Musiatowiwcz, Mariusz Koda, Stanisław Sulkowski Tags: Research papers Source Type: research

The role of sinus surgery in children
ConclusionsESS offers a surgical alternative in the treatment of CRS in children with an excellent safety profile. There remains a need for higher level studies addressing the indications of ESS in children. Level of Evidence2a Laryngoscope, 2013 (Source: The Laryngoscope)
Source: The Laryngoscope - January 29, 2013 Category: ENT & OMF Authors: Chadi A. Makary, Hassan H. Ramadan Tags: Allergy/Rhinology Source Type: research

Reversal of pulmonary hypertension in children after adenoidectomy or adenotonsillectomy
Abstract: Introduction: Adenotonsillar hypertrophy is a common condition in pediatric patients with upper respiratory airways complaints, and pulmonary arterial hypertension (PAH) may be one complication of that condition.Objectives: To study the occurrence of PAH (mean pulmonary artery pressure higher than or equal to 25mmHg) in a group of children with adenotonsillar hypertrophy and upper respiratory complaints (snoring or oral breathing), and to verify the pulmonary arterial pressure (PAP) changes after adenotonsillectomy.Study design: Case–control prospective study.Settings: Study conducted at São Lucas Hospital, ap...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Viviane Feller Martha, José da Silva Moreira, Aline Silveira Martha, Flávio José Velho, Renato George Eick, Sandro Cadaval Goncalves Tags: Research papers Source Type: research

Hearing 25 years after surgical treatment of otitis media with effusion in early childhood
Conclusions: Hearing 25 years after surgical treatment of chronic OME is not different from age and gender matched normal hearing. In addition, treatment modality (myringotomy or ventilation tube) has no impact on the long-term hearing level. However, atrophy is associated with a hearing loss in tubed ears, whereas myringosclerosis is associated with a hearing loss in myringotomised ears. The hearing loss associated with pathology is of limited magnitude (up to about 5dB PTA). Even though pathology does occur more frequently and more extensively in tubed ears, the effect on the hearing at the group level is too small to ha...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Mojgan Khodaverdi, Gita Jørgensen, Theis Lange, Sven-Eric Stangerup, Dominika Drozdziewizc, Mirko Tos, Per Bonding, Per Caye-Thomasen Tags: Research papers Source Type: research

Recurrent tube insertion for chronic otitis media with effusion in children over 6 years
Abstract: Objective: The purpose of this study is to identify the clinical characteristics of children above 6 years of age with chronic otitis media with effusion (COME) who have required pressure equalizing tube (PET) insertions.Methods: A retrospective chart review was performed of all children above the age of 6 years, who underwent PET insertion due to chronic OME, between 2000 and 2009 at a tertiary care institution. Children were also divided into those with a single PET and those with ≥2 PET. Comparison of various characteristics between the two groups was undertaken.Results: 290 children were identified as havin...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Cinzia L. Marchica, Jacob Pitaro, Sam J. Daniel Tags: Research papers Source Type: research

CADTH Rapid Response Report: Optimal pain management following tonsillectomy or adenoidectomy for paediatric patients
Source: Canadian Agency for Drugs and Technologies in Health (CADTH) Area: News This Rapid Response Report by the Canadian Agency for Drugs and Technologies in Health (CADTH) reviews the available clinical evidence and evidence-based guidelines regarding optimal pharmaceutical pain management options for paediatric patients following tonsillectomy and/or adenoidectomy. A limited literature search of key resources identified two systematic reviews and five randomised controlled trials. Although a variety of pharmaceutical pain management options were examined, none of the studies identified an optimal pain manag...
Source: NeLM - News - January 14, 2013 Category: Drugs & Pharmacology Source Type: news

Effects of guidelines on adeno-tonsillar surgery on the clinical behaviour of otorhinolaryngologists in Italy
Conclusions: The recommendations first developed in Italy in a 2003 policy document and then resumed in guidelines in 2008, were not implemented by ENT units involved in the survey. The study highlights the fact that the indications for adeno-tonsillar operations are based on the overall clinical presentation (comorbidity) rather than on a single symptom. Guidelines are necessary to give coherent recommendations based on both the findings obtained through randomized controlled trials and the data collected from observational studies. (Source: BMC Ear, Nose and Throat Disorders)
Source: BMC Ear, Nose and Throat Disorders - January 7, 2013 Category: ENT & OMF Authors: Giovanni MottaSergio MottaPasquale CassanoSalvatore ConticelloMassimo FerrettiBruno GallettiAldo GarozzoGennaro LarotondaNicola MansiEmilio MevioGaetano MottaGiuseppe QuarembaAgostino SerraVincenzo TarantinoPaolo TavorminaClaudio ViciniMaurizio VigiliDome Source Type: research

Kids Younger Than 5 Years at Risk for Repeat AdenoidectomyKids Younger Than 5 Years at Risk for Repeat Adenoidectomy
Data from more than 10,000 children show that a lack of tonsillectomy is also associated with the need for a repeat procedure. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2012 Category: Consumer Health News Tags: Pediatrics News Source Type: news

The laryngeal mask airway for pediatric adenotonsillectomy: Predictors of failure and complications
Abstract: Objectives: We hypothesize that the laryngeal mask airway (LMA) is a safe technique for airway management in pediatric adenotonsillectomy (T&A).Methods: After institutional review board (I.R.B.) approval, we conducted a retrospective review of 1199 medical records of children who underwent T&A from 2002 to 2006 at Doernbecher Children's Hospital, a teaching institution in Portland, OR. There were no significant demographic differences between the LMA (n=451), endotracheal tube (ETT) (n=715), and failed LMA groups (n=33). Outcome variables were LMA failure (LMA replaced with endotracheal tube), and any complicatio...
Source: International Journal of Pediatric Otorhinolaryngology - December 27, 2012 Category: ENT & OMF Authors: Kirk Lalwani, Scott Richins, Inger Aliason, Henry Milczuk, Rongwei Fu Tags: Research papers Source Type: research

Adenoid regrowth in young kids "a real problem"
NEW YORK (Reuters Health) - Children younger than age five who have their adenoids removed without having their tonsils removed are at increased risk of needing repeat adenoidectomy, researchers discovered in a large medical record review. (Source: Modern Medicine)
Source: Modern Medicine - December 21, 2012 Category: Journals (General) Source Type: news

Tonsilloplasty versus tonsillectomy in children with sleep‐disordered breathing: Short‐ and long‐term outcomes
Conclusions:TP is an alternative surgical method for treatment of SDB related to tonsillar hypertrophy with favorable postoperative course and comparable long‐term results. Laryngoscope, 2012 (Source: The Laryngoscope)
Source: The Laryngoscope - December 19, 2012 Category: ENT & OMF Authors: Konstantinos S. Chaidas, Athanasios G. Kaditis, Chariton E. Papadakis, Nikolaos Papandreou, Petros Koltsidopoulos, Charalampos E. Skoulakis Tags: Sleep Medicine Source Type: research

MHRA Drug Safety Update: European safety review of codeine-containing pain relief in children following post-surgical fatalities in ultra-rapid metabolisers
Source: MHRA Area: News The December issue of the MHRA's Drug Safety Update discusses a European review of the safety of medicines containing codeine licensed for pain relief in children (aged 0-18 years), which was started in October 2012. This review was triggered by recent concerns that there is an increased risk of morphine toxicity when certain susceptible children are given codeine for post-operative pain. These concerns follow the reporting of three fatalities, and one life-threatening case of respiratory depression in children given codeine after tonsillectomy or adenoidectomy in the treatment of obstructive sleep...
Source: NeLM - News - December 14, 2012 Category: Drugs & Pharmacology Source Type: news

Effect of Different Depths of Anesthesia on Perioperative Stress Response in Children Undergoing Adenoidectomy and Tonsillectomy.
PMID: 23241353 [PubMed - as supplied by publisher] (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - December 14, 2012 Category: Neuroscience Authors: Yang LQ, Li JJ, Chen SQ, Wang YW Tags: CNS Neurosci Ther Source Type: research

Role of adenoid biofilm in chronic otitis media with effusion in children
This study focused on the value of PCR in detecting pathogens in the adenoid and middle ear specimens although the bacterial culture would be negative. Content Type Journal ArticleCategory OtologyPages 1-9DOI 10.1007/s00405-012-2259-1Authors Magdy Eisa Saafan, Department of Otolaryngology and Head & Neck Surgery, Tanta University Hospitals, 61 Kafr Esam Street El Nadi Square, Tanta, EgyptWesam Salah Ibrahim, Department of Clinical Pathology, Tanta University Hospitals, 61 Kafr Esam Street El Nadi Square, Tanta, EgyptMohamed Osama Tomoum, Department of Otolaryngology and Head & Neck Surgery, Tanta University Hospita...
Source: European Archives of Oto-Rhino-Laryngology - November 25, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research

Patient‐recorded outcomes and quality of life in evidence‐based medicine databases on most common ear, throat and nose procedures: a systematic review
ConclusionsSince the introduction of QoL instruments in the 1990s, their use has gradually increased, but validated QoL instruments have been used in only one out of ten RCTs included in EBM databases. Ongoing RCTs consider QoL only slightly more often.© 2012 Blackwell Publishing Ltd (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - November 12, 2012 Category: ENT & OMF Authors: Alakärppä Antti, Alho O.‐P Tags: Review Source Type: research

Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement
We report a patient with dysfibrinogenemia treated with purified fibrinogen concentrate who had discrepant post‐treatment laboratory values. The patient had mild bleeding symptoms and was diagnosed with dysfibrinogenemia based on fibrinogen activity of 51 mg/dl and antigen of 240 mg/dl. He was treated for an adenoidectomy with purified fibrinogen concentrate (RiaSTAP®) at a dose of 70 mg/kg. A discrepancy in post‐treatment fibrinogen activity was observed between the hospital and reference laboratories. Investigation revealed differences in laboratory assay and calibration methods. Fibrinogen concentrate may be ...
Source: Pediatric Blood and Cancer - November 5, 2012 Category: Cancer & Oncology Authors: Emily B. Franzblau, Rowena C. Punzalan, Kenneth D. Friedman, Angshumoy Roy, Ozlem Bilen, Veronica H. Flood Tags: Brief Report Source Type: research

Sleep Apnea in Early Childhood Associated with Preterm Birth but Not Small for Gestational Age: A Population-Based Record Linkage Study
Conclusions:This is the largest study investigating preterm birth and sleep apnea diagnosis and suggests that diagnosis of sleep disordered breathing is more prevalent in children born preterm, but not those who are small for gestational age.Citation:Raynes-Greenow CH; Hadfield RM; Cistulli PA; Bowen J; Allen H; Roberts CL. Sleep apnea in early childhood associated with preterm birth but not small for gestational age: a population-based record linkage study. SLEEP 2012;35(11):1475-1480. (Source: Sleep)
Source: Sleep - October 31, 2012 Category: Sleep Medicine Source Type: research

Tonsil & Adenoid Removal Reduces Asthma
(Ivanhoe Newswire) – Children with asthma who have their tonsils and adenoids (T&A) removed may experience fewer asthma symptoms. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - October 24, 2012 Category: Consumer Health News Source Type: news

Pediatric Asthma Symptoms Reduced By Tonsil And Adenoid Removal
Children with asthma who have their tonsils and adenoids (T&A) removed may experience fewer asthma symptoms. Researchers from Children's Hospital and Research Center in Oakland, California, followed 105 children with asthma (7-21 years) referred for sleep study for suspected sleep apnea. Twenty-four patients with sleep apnea required T&A, of which 11 patients followed through with surgery. Results indicated that asthma scores trended toward improvement with T&A. However, there was no significant increase in the lung function following T&A... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 23, 2012 Category: Consumer Health News Tags: Ear, Nose and Throat Source Type: news

Light microscopic histopathology of adenoid tissue in otitis media with effusion: Is there any relation?
Conclusions: The role of the adenoids in pathogenesis of otitis media with effusion is beyond its histopathologic changes at least in the level of light microscopic findings. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - October 19, 2012 Category: ENT & OMF Authors: Ali Eftekharian, Shahram Sabeti, Mahdi Khajavi, Latif Gachkar, Mahshid Khordechi Tags: Research papers Source Type: research

Adenoidectomy in young children and serum IgG antibodies to pneumococcal surface protein A and choline binding protein A
Conclusions: Adenoidectomy in young children causes a small but detectable impairment in the development of serum IgG antibodies to pneumococcal CbpA. The adenoid seems to have a role in augmenting systemic immunity against pneumococci. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - October 19, 2012 Category: ENT & OMF Authors: Petri S. Mattila, Sari Hammarén-Malmi, Harri Saxen, Tarja Kaijalainen, Helena Käyhty, Jussi Tarkkanen Tags: Research papers Source Type: research

Children with severe or moderate obstructive sleep apnoea syndrome show a high incidence of persistence after adenotonsillectomy.
Conclusion: Persistent obstructive sleep apnoea syndrome (OSAS) occurs in approximately 20% of normal-weight children after adenotonsillectomy (T&A) and, in nearly 70% of them, it is caused by adenoid regrowth. Patients with severe or moderate OSAS showed a high incidence of persistent disease even after T&A. Allergic disease, severity and large adenoid size are associated with adenoid regrowth and persistent disease. Objectives: To investigate factors contributing to persistent OSAS and adenoid regrowth after T&A in normal-weight children. Methods: This was a prospective, observational study at a single instit...
Source: Acta Oto-Laryngologica - October 16, 2012 Category: ENT & OMF Authors: Tagaya M, Nakata S, Yasuma F, Mitchell RB, Sasaki F, Miyazaki S, Morinaga M, Otake H, Teranishi M, Nakashima T Tags: Acta Otolaryngol Source Type: research

European Medicines Agency to review safety of codeine-containing medicines used post-op for children
Source: European Medicines Agency Area: News The European Medicines Agency (EMA)'s Pharmacovigilance Risk Assessment Committee (PRAC) has started its first safety review of a medicine under the new EU rules on pharmacovigilance. The review will consider the safety of codeine-containing medicines when used for post-operative pain relief in children. It has been initiated at the request of the UK medicines agency on the basis of recent concerns over an increased risk of morphine toxicity when codeine is given in this setting. In particular, a very small number of cases of rare but fatal or life-threatening respi...
Source: NeLM - News - October 8, 2012 Category: Drugs & Pharmacology Source Type: news

Reactive Tonsillar Enlargement Showing Strong 18F-Fdg Uptake During the Follow-Up of Follicular Lymphoma
We report a case of a 40-year-old man with a previous history of a nodal follicular lymphoma, stage IVA, treated with R-CHOP, which showed strong 18F-FDG uptake in the Waldeyer’s tonsillar ring during his follow-up, being considered highly suspicious of relapsed lymphoma. A surgical removal of the palatine tonsils and adenoids was performed, which showed reactive follicular hyperplasia. Furthermore, bone marrow biopsy revealed absence of neoplasia. The patient is still in follow-up with no signs of recurrent lymphoma. This case illustrates that, despite the high sensitivity for the detection of recurrent lymphoma, 18...
Source: Head and Neck Pathology - September 25, 2012 Category: Pathology Tags: Head and Neck Pathology Source Type: research

Antibiotics for otitis media with effusion in children
Source: Cochrane Area: Evidence > Disease Focused Reviews Background Otitis media with effusion (OME) is characterised by an accumulation of fluid in the middle ear behind an intact tympanic membrane, without the symptoms or signs of acute infection. In approximately one in three children with OME, however, a bacterial pathogen is identified in the middle ear fluid. In most cases, OME causes mild hearing impairment of short duration. When experienced in early life and when episodes of (bilateral) OME persist or recur, the associated hearing loss may be significant and have a negative impact on speech development and b...
Source: NeLM - Disease Focused Reviews - September 23, 2012 Category: Internal Medicine Source Type: news

Microdebrider tonsillectomy associated with more intraoperative blood loss than electrocautery
Abstract: Objective: To describe and compare the intraoperative blood loss in children who underwent tonsillectomy and/or adenoidectomy during a transition from using electrocautery to a microdebrider.Methods: Retrospective case series of a single pediatric otolaryngologist at an urban general hospital. Patients aged 2–20 years who had tonsillectomy, adenoidectomy, or adenotonsillectomy over a 12 month period were included. Tonsillectomy was performed by microdebrider or electrocautery and adenoidectomy was performed by microdebrider, curette, or suction electrocautery. Total intraoperative blood loss was measured and co...
Source: International Journal of Pediatric Otorhinolaryngology - September 20, 2012 Category: ENT & OMF Authors: Kyle J. Stansifer, Molly G. Szramowski, Lindsay Barazsu, Farrel J. Buchinsky Tags: Research papers Source Type: research

Does Your Child Snore? It May Signal Behavioral Problems
If your toddler snores, don’t ignore it. Loud, constant snoring in 2 to 3-year olds may be connected to behavioral problems, according to a recent study published online in Pediatrics. In the study, 9% of children who snored loudly were more likely to have behavioral issues than those who didn’t snore. “Snoring in children is not normal,” says Richard M. Kravitz, M.D., a specialist in in pediatric sleep disorders at Duke Children’s Hospital and Health Center. “My rule is if your child snores, you have to ask more.” According to Kravitz, snoring in children is caused by a narrowing of the upper airway, most co...
Source: DukeHealth.org: Duke Health Features - September 8, 2012 Category: Pediatrics Tags: Primary Care Services Source Type: news

The effectiveness of tonsillectomy and partial adenoidectomy on obstructive sleep apnea in cleft palate patients
Conclusions:In most cases, tonsillectomy and/or partial adenoidectomy is an effective method for treatment of OSA in repaired cleft palate patients presenting with tonsillar and/or adenoid hypertrophy. However, some cases may need further procedures to relieve airway obstruction due to associated comorbidities. (Source: The Laryngoscope)
Source: The Laryngoscope - September 5, 2012 Category: ENT & OMF Authors: Mosaad Abdel‐Aziz Tags: Pediatrics Source Type: research

Codeine after tonsillectomy can be fatal
Some children who receive typical doses of codeine for pain relief after tonsillectomy or adenoidectomy may suffer life-threatening adverse effects or death, a drug-safety communication from the US Food and Drug Administration (FDA) warns. More >> (Source: Modern Medicine Contemporary Pediatrics)
Source: Modern Medicine Contemporary Pediatrics - August 23, 2012 Category: Pediatrics Source Type: news

Nationwide survey of acromegaly in South Korea
ConclusionsThis Korean acromegaly survey offers a realistic overview of the predominant epidemiological characteristics of acromegaly in Korea. Annual incidence was at a similar level with western countries. Efforts to diagnose and control the disease earlier are recommended.© 2012 Blackwell Publishing Ltd (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - August 21, 2012 Category: Endocrinology Authors: Obin Kwon, Young Duk Song, Seong Yeon Kim, Eun Jig Lee, Tags: Original Article Source Type: research

Is There a Relationship Between Serum Levels of Vitamin A, Vitamin E, Copper and Zinc and Otitis Media with Effusion in Children?
Abstract The aim of this study is to determine whether the serum levels of vitamin A, vitamin E, copper and zinc have a role in the development of otitis media with effusion (OME) in childhood. This prospective study was conducted between February 2010 and February 2011 at a tertiary Otorhinolaryngoloy Clinic. There were 113 subjects and subdivided into three groups. Group 1 consisted of 44 patients who underwent adenoidectomy with ventilation tube placement due to OME. Group 2 consisted of 43 patients underwent adenoidectomy alone and group 3,called control group, included 26 healthy children. Serum values ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - August 20, 2012 Category: ENT & OMF Tags: Indian Journal of Otolaryngology and Head & Neck Surgery Source Type: research

FDA to review risk of rare, but life-threatening adverse events or death associated with codeine use in certain children after tonsillectomy and/or adenoidectomy
Source: FDA Area: News The Food and Drug Administration (FDA) has issued a Drug Safety Communication in the United States to advise that it is reviewing reports of children who developed serious adverse effects or died after taking codeine for pain relief after tonsillectomy and/or adenoidectomy for obstructive sleep apnoea syndrome. Recently, three paediatric deaths and one non-fatal but life-threatening case of respiratory depression were documented in the medical literature. The children (ages two to five) had evidence of an inherited ability to convert codeine into life-threatening or fatal amounts of morph...
Source: NeLM - News - August 16, 2012 Category: Drugs & Pharmacology Source Type: news

FDA Warns of Deaths with Postop Codeine in Children
WASHINGTON (MedPage Today) -- The FDA issued a warning Wednesday of a potentially fatal risk associated with the use of codeine in children following tonsillectomy and adenoidectomy. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - August 15, 2012 Category: Pediatrics Source Type: news

FDA warns of risk of death from codeine use in some children following surgeries
The U.S. Food and Drug Administration today issued a Drug Safety Communication concerning three children who died and one child who experienced a non-fatal but life-threatening case of respiratory depression after taking the pain reliever codeine following surgery to remove tonsils (tonsillectomy) and/or adenoids (adenoidectomy). (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 15, 2012 Category: American Health Source Type: news

Codeine Use in Certain Children After Tonsillectomy and/or Adenoidectomy: Drug Safety Communication - Risk of Rare, But Life-Threatening Adverse Events or Death
Ultra-rapid metabolizers are more likely to have higher than normal amounts of morphine in their blood after taking codeine. High levels of morphine can result in breathing difficulty, which may be fatal. (Source: FDA MedWatch)
Source: FDA MedWatch - August 15, 2012 Category: American Health Source Type: news

FDA cautions about codeine after tonsillectomy, adenoidectomy [News and Features]
(Source: AAP News)
Source: AAP News - August 15, 2012 Category: Pediatrics Tags: News and Features Source Type: research

Codeine Use in Certain Children After Tonsillectomy and/or Adenoidectomy: Drug Safety Communication - Risk of Rare, But Life-Threatening Adverse Events or Death
Audience: Pediatricians, Surgery, Consumer ISSUE: The FDA is reviewing reports of children who developed serious adverse effects or died after taking codeine for pain relief after tonsillectomy and/or adenoidectomy for obstructive sleep apnea... (Source: Drugs.com - FDA MedWatch Alerts)
Source: Drugs.com - FDA MedWatch Alerts - August 15, 2012 Category: Drugs & Pharmacology Source Type: news

FDA warns of possible fatalities from codeine use in some children after surgical procedures
FDA has issued a Drug Safety Communication concerning three children who died and one child who experienced a nonfatal but life-threatening case of respiratory depression after taking the pain-reliever codeine following tonsillectomy and/or adenoidectomy. (Source: Drug Topics - Pharmacy News)
Source: Drug Topics - Pharmacy News - August 15, 2012 Category: Pharmaceuticals Source Type: news

FDA warns of possible fatalities from codeine use in some children after surgical procedures
FDA has issued a Drug Safety Communication concerning three children who died and one child who experienced a nonfatal but life-threatening case of respiratory depression after taking the pain-reliever codeine following tonsillectomy and/or adenoidectomy. (Source: Modern Medicine)
Source: Modern Medicine - August 15, 2012 Category: Journals (General) Source Type: news

FDA warns of possible fatalities from codeine use in some children after surgical procedures
FDA has issued a Drug Safety Communication concerning three children who died and one child who experienced a nonfatal but life-threatening case of respiratory depression after taking the pain-reliever codeine following tonsillectomy and/or adenoidectomy. (Source: Drug Topics - Top News)
Source: Drug Topics - Top News - August 15, 2012 Category: Drugs & Pharmacology Source Type: news

Validation of a clinical assessment score for pediatric sleep‐disordered breathing
Conclusions:The CAS‐15 proved useful in an office setting and correctly diagnosed 72% of referred children when compared to polysomnography. It correlated well with external measures and demonstrated a good response to clinical change. (Source: The Laryngoscope)
Source: The Laryngoscope - August 13, 2012 Category: ENT & OMF Authors: Nira A. Goldstein, Dimitre G. Stefanov, Katharina D. Graw‐Panzer, Samir A. Fahmy, Sherry Fishkin, Alison Jackson, Jennifer S. Sarhis, Jeremy Weedon Tags: Pediatrics: Triological Society Candidate Thesis Source Type: research

The role of bronchoscopy in the management of patients with severe craniofacial syndromes
Conclusions: Airway anomalies occurred in 70% of children with severe craniofacial syndromes and respiratory symptoms. Bronchoscopy should be performed routinely in this selected group of patients, and the entire airway must be examined. Treatment should be tailored to each individual patient. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - August 1, 2012 Category: Surgery Authors: Juan L. Antón-Pacheco, Carmen Luna Paredes, Antonio Martínez Gimeno, Gloria García Hernández, Rubén Martín de la Vega, Ana Romance García Tags: Original Articles Source Type: research

Utility of preoperative hematologic screening for pediatric adenotonsillectomy.
In conclusion, we found that preoperative hematologic screening identified patients with undiagnosed coagulopathies, and with appropriate treatment our surgeons were able to prevent some bleeding events in these patients. Our finding that patients with a mildly elevated INR had a higher incidence of postoperative hemorrhage warrants further study. PMID: 22930084 [PubMed - in process] (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - August 1, 2012 Category: ENT & OMF Authors: Koshkareva YA, Cohen M, Gaughan JP, Callanan V, Szeremeta W Tags: Ear Nose Throat J Source Type: research