Covishield Side Effects: What's TTS syndrome, symptoms, and danger signs you shouldn't ignore
Covishield TTS: AstraZeneca has acknowledged the potential TTS side effects from its COVID-19 vaccine Covishield, used widely in India. TTS, Thrombosis with Thrombocytopenia Syndrome, is rare but serious, marked by blood clots and low platelet levels. Symptoms include headaches, blurred vision, and chest pain. Dr. Jayadevan emphasizes awareness, stressing early treatment for effective management. AstraZeneca's admission follows reports of TTS linked to adenovirus vector vaccines. (Source: The Economic Times)
Source: The Economic Times - April 30, 2024 Category: Consumer Health News Source Type: news
U.S. FDA approves Pfizer & #039;s BEQVEZ ™ (fidanacogene elaparvovec-dzkt), a one-time gene therapy for adults with Hemophilia B
Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved BEQVEZ™ (fidanacogene elaparvovec-dzkt) for the treatment of adults with moderate to severe hemophilia B who currently use factor IX (FIX) prophylaxis therapy, or have current or historical life-threatening hemorrhage, or have repeated, serious spontaneous bleeding episodes, and do not have neutralizing antibodies to adeno-associated virus serotype Rh74var (AAVRh74var) capsid as detected by an FDA-approved test. (Source: World Pharma News)
Source: World Pharma News - April 26, 2024 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news
Gene therapies that let deaf children hear bring hope —and many questions
The past few months have brought electrifying news that, for the first time, a gene therapy has provided some hearing to children born with mutations that left them deaf. Eli Lilly
announced
this week, for example, that a profoundly deaf boy from Morocco given its treatment as part of a clinical trial in Philadelphia can now hear. And five children in China treated similarly at younger ages gained hearing with some able to verbally communicate without their cochlear implants. Their hearing recovery, first covered by the
press
in October 2023, is described in detail this week in
The Lancet
...
Source: ScienceNOW - January 26, 2024 Category: Science Source Type: news
Next-Level Adeno-Associated Virus (AAV) Production
Take the leap from shake flasks to bioreactors. (Source: The Scientist)
Source: The Scientist - January 2, 2024 Category: Science Tags: The Marketplace Source Type: news
What Causes Conjunctivitis? A Panoply of Pathogens, Study Shows
(MedPage Today) -- Pathogens associated with acute infectious conjunctivitis varied among regions, a cross-sectional study showed.
Among 52 patients from four sites in the U.S. and one in Israel, RNA deep sequencing found human adenovirus species... (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - November 3, 2023 Category: Pediatrics Source Type: news
Africa: Why Some People Got Blood Clots After the Astrazeneca Vaccine - New Clues
[The Conversation Africa] AstraZeneca in partnership with the University of Oxford developed one of the first vaccines against COVID. The vaccine, which used an adenovirus to smuggle instructions into human cells to make antibodies against the novel coronavirus, saved countless lives. But a problem soon emerged. A tiny proportion - about one in 50,000 - of those vaccinated developed blood clots. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 31, 2023 Category: African Health Tags: Africa Coronavirus Health and Medicine Source Type: news
How Many Diphtheria Vaccines are Currently Licensed in the US?
Discussion
Diphtheria is caused by the toxin produced by Corynebacterium diphtheriae. Two other Corynebacterium species (C. ulcerans and C. pseudotuberculosis) may produce diphtheria toxin; both species are zoonotic. Diphtheria is spread by respiratory droplets and also contact with open ulcers or sores. Incubation period is 1-10 days with a usual period of 2-5 days. The bacteria attacks the respiratory tract mucosa causing cellular death which in turn causes a “pseudomembrane” of tissue to build up causing respiratory distress and possible death due to airway obstruction (5-10% for general population but up to...
Source: PediatricEducation.org - September 25, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Gene Therapy Promising for Rare Jaundice Syndrome
(MedPage Today) -- Gene therapy for Crigler-Najjar syndrome appeared promising in patients treated at a higher dose, a phase I/II trial showed.
A single infusion of GNT0003 -- an adeno-associated virus serotype 8 vector carrying a correction... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - August 17, 2023 Category: Gastroenterology Source Type: news
Adenovirus May Trigger Thrombocytopenia, Thrombosis, Case Studies Suggest
(MedPage Today) -- In rare cases, symptomatic human adenovirus infection may trigger a life-threatening prothrombotic anti-platelet factor 4 (PF4) disorder resembling vaccine-induced immune thrombotic thrombocytopenia (VITT), according to a report... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 9, 2023 Category: Cardiology Source Type: news
Monthly News Roundup - June 2023
Elevidys is First Gene Therapy Cleared to Treat Duchenne Muscular Dystrophy
In June, the FDA granted accelerated approval of Elevidys (delandistrogene moxeparvovec-rokl) from Sarepta Therapeutics, Inc. Elevidys is an adeno-associated virus... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 30, 2023 Category: Pharmaceuticals Source Type: news
Controversial Gene Therapy Wins FDA Approval for Duchenne Muscular Dystrophy
(MedPage Today) -- The FDA granted accelerated approval to delandistrogene moxeparvovec (Elevidys), the first gene therapy for Duchenne muscular dystrophy, the agency announced Thursday.
The adeno-associated virus-based gene therapy is a one-time... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 22, 2023 Category: Neurology Source Type: news
Children are catching flu more often now: Medical experts
A lot of children under the age of 15 are getting infected with adenovirus and Covid-19, with some cases leading to complications like pneumonia, doctors said. (Source: The Economic Times)
Source: The Economic Times - April 12, 2023 Category: Consumer Health News Source Type: news
What Causes Parotitis?
Discussion
The salivary glands are important for creating saliva which helps with taste, digestion, oral health, and speech. Salivary gland problems are not that common but can be painful, annoying or herald potential systemic diseases. The parotid gland is the largest salivary gland lying anterior to the ear within the cheek structures. There are 2 lobes (superficial and deep) and the facial nerve runs between them. The salivary duct opens adjacent to the upper second molar. Infections are the most common cause of parotitis with mumps being the most commonly associated infection especially in unimmunized patients.
Patient...
Source: PediatricEducation.org - April 10, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
U.S. Study Backs 'Helper' Virus Theory in Kids' Mystery Hepatitis Cases
(MedPage Today) -- Genotyping results from blood samples of U.S. children with severe acute hepatitis of unknown cause support prior research suggesting that adeno-associated virus 2 (AAV2) along with a "helper" virus may be to blame for last year... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 31, 2023 Category: Gastroenterology Source Type: news
